Il1a (interleukin 1 alpha) - Rat Genome Database

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Gene: Il1a (interleukin 1 alpha) Rattus norvegicus
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Symbol: Il1a
Name: interleukin 1 alpha
RGD ID: 2890
Description: Predicted to enable copper ion binding activity; cytokine activity; and interleukin-1 receptor binding activity. Involved in several processes, including keratinization; negative regulation of establishment of Sertoli cell barrier; and positive regulation of intracellular signal transduction. Located in several cellular components, including cell surface; cytosol; and extracellular space. Used to study interstitial lung disease. Biomarker of several diseases, including endometritis; lung disease (multiple); urinary tract infection; uveitis; and varicocele. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Schnitzler syndrome; autoimmune disease (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to human IL1A (interleukin 1 alpha); PARTICIPATES IN interleukin-1 signaling pathway; apoptotic cell death pathway; cytokine mediated signaling pathway; INTERACTS WITH (R)-lipoic acid; (R)-mevalonic acid; (R,R,R)-alpha-tocopherol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: IL-1 alpha; IL-1F1; interleukin-1 alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23116,526,601 - 116,537,055 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3116,526,604 - 116,536,822 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3120,424,348 - 120,434,552 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.03129,019,955 - 129,030,165 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.03126,680,432 - 126,690,642 (-)NCBIRnor_WKY
Rnor_6.03121,824,712 - 121,836,122 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3121,825,412 - 121,836,086 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03128,180,475 - 128,190,980 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43116,913,612 - 116,924,114 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13116,819,184 - 116,829,687 (-)NCBI
Celera3115,352,857 - 115,362,929 (-)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (ISO)
acute myeloid leukemia  (ISO)
allergic bronchopulmonary aspergillosis  (ISO)
allergic contact dermatitis  (ISO)
Alzheimer's disease  (ISO)
amnestic disorder  (ISO)
Anorexia  (IEP)
anthracosis  (ISO)
Arsenic Poisoning  (ISO)
aspiration pneumonia  (IEP)
asthma  (ISO)
autoimmune thrombocytopenic purpura  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
beta thalassemia  (ISO)
Brain Injuries  (IEP,ISO)
brain ischemia  (ISO)
Burns  (ISO)
cardiomyopathy  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chemical Burns  (ISO)
cholestasis  (IEP)
cholesteatoma  (ISO)
cholesteatoma of middle ear  (ISO)
chorioamnionitis  (ISO)
chronic progressive external ophthalmoplegia  (ISO)
common cold  (ISO)
corneal edema  (ISO)
Craniocerebral Trauma  (ISO)
Creutzfeldt-Jakob disease  (ISO)
cystic fibrosis  (ISO)
dermatomyositis  (ISO)
diabetic retinopathy  (ISO)
diarrhea  (ISO)
Disease Progression  (ISO)
Drug-Induced Immune Thrombocytopenia  (ISO)
Drug-induced Neutropenia  (ISO)
end stage renal disease  (ISO)
endometritis  (IEP)
Endotoxemia  (IEP,ISO)
Enterocolitis  (IEP)
Experimental Arthritis  (IDA,IEP)
Experimental Diabetes Mellitus  (IEP)
Experimental Leukemia  (ISO)
Experimental Melanoma  (ISO)
extrinsic allergic alveolitis  (ISO)
Fabry disease  (ISO)
Femoral Fractures  (IEP)
Fetal Growth Retardation  (ISO)
Fever  (ISO)
glomerulonephritis  (ISO)
graft-versus-host disease  (ISO)
Graves ophthalmopathy  (ISO)
head and neck squamous cell carcinoma  (ISO)
Heat Stroke  (IEP,ISO)
hemolytic-uremic syndrome  (ISO)
Hemorrhage  (IEP)
Hemorrhagic Shock  (IEP)
HIV Wasting Syndrome  (ISO)
Human Influenza  (ISO)
Hyperalgesia  (ISO)
hyperglycemia  (ISO)
Hypotension  (ISO)
IgA glomerulonephritis  (ISO)
Inflammation  (ISO)
interstitial lung disease  (IMP,ISO)
Invasive Pulmonary Aspergillosis  (ISO)
iridocyclitis  (ISO)
juvenile rheumatoid arthritis  (ISO)
Kearns-Sayre syndrome  (ISO)
keratoconus  (ISO)
Knee Osteoarthritis  (IEP,ISO)
Leber hereditary optic neuropathy  (ISO)
Liver Reperfusion Injury  (IDA,IEP)
lung disease  (ISO)
lung non-small cell carcinoma  (ISO)
malignant mesothelioma  (ISO)
MELAS syndrome  (ISO)
MERRF Syndrome  (ISO)
mesenchymal chondrosarcoma  (ISO)
Middle East respiratory syndrome  (ISO)
mitochondrial myopathy  (ISO)
multiple myeloma  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (IEP,ISO)
Nasal Polyps  (ISO)
non-alcoholic fatty liver disease  (ISO)
Oral Lichen Planus  (ISO)
osteoarthritis  (ISO)
osteoporosis  (ISO)
otitis media  (IEP)
pancreatic cancer  (ISO)
Perennial Allergic Rhinitis  (ISO)
periodontitis  (ISO)
pneumonia  (IEP)
Poisoning  (ISO)
polymyositis  (ISO)
pulmonary fibrosis  (IEP,ISO)
pulmonary tuberculosis  (ISO)
Radiation Injuries  (IEP)
Radiation Pneumonitis  (ISO)
Reperfusion Injury  (ISO)
respiratory allergy  (ISO)
Retina Reperfusion Injury  (IEP)
rheumatoid arthritis  (ISO)
Schnitzler syndrome  (ISO)
Sclerosis  (ISO)
severe acute respiratory syndrome  (ISO)
skin disease  (ISO)
Skin Neoplasms  (ISO)
tick infestation  (ISO)
type 1 diabetes mellitus  (ISO)
urinary tract infection  (IEP,ISO)
uveitis  (IEP)
varicocele  (IEP)
Venous Thrombosis  (IEP)
vitiligo  (ISO)
Wounds and Injuries  (IEP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-epicatechin-3-O-gallate  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(E)-cinnamyl alcohol  (ISO)
(R)-lipoic acid  (EXP)
(R)-mevalonic acid  (EXP,ISO)
(R,R,R)-alpha-tocopherol  (EXP)
(S)-colchicine  (ISO)
(S)-nicotine  (ISO)
1,1'-azobis(N,N-dimethylformamide)  (ISO)
1,3-benzothiazole-2-thiol  (ISO)
1,3-dinitrobenzene  (EXP)
1,4-dithiothreitol  (ISO)
1,4-phenylenediamine  (ISO)
1-(alpha-Methyl-4-(2-methylpropyl)benzeneacetate)-beta-D-Glucopyranuronic acid  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP,ISO)
1-nitropyrene  (ISO)
1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine  (ISO)
1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2'-bipyridine  (ISO)
2,2,2-trichloroethanol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-bis(4-hydroxyphenyl)propionitrile  (EXP)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-hydroxypropanoic acid  (ISO)
2-methoxy-17beta-estradiol  (EXP)
2-tert-butylhydroquinone  (ISO)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (EXP,ISO)
22-Hydroxycholesterol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3-acetyldeoxynivalenol  (ISO)
3-methylcholanthrene  (ISO)
3-phenylprop-2-enal  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nitrobenzyl bromide  (ISO)
4-phenylbutyric acid  (ISO)
4-tert-butylphenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
8-Br-cAMP  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (EXP)
actinomycin D  (EXP)
acyclovir  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP)
albendazole  (ISO)
albuterol  (ISO)
aldehydo-D-glucosamine  (EXP)
all-trans-retinoic acid  (EXP,ISO)
alpha-hexylcinnamaldehyde  (ISO)
aluminium oxide  (ISO)
amikacin  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP)
amodiaquine  (ISO)
amphibole asbestos  (ISO)
aniline  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
anthracene-1,8,9-triol  (ISO)
arachidonic acid  (ISO)
aripiprazole  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
asbestos  (ISO)
ATP  (ISO)
azathioprine  (ISO)
BAPTA  (ISO)
benzalkonium chloride  (ISO)
benzatropine  (ISO)
benzbromarone  (ISO)
benzene  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzoates  (ISO)
benzocaine  (ISO)
benzoic acid  (ISO)
Benzoyl peroxide  (ISO)
benzyl alcohol  (ISO)
benzylpenicillin  (ISO)
beta-D-glucosamine  (EXP)
beta-naphthoflavone  (EXP,ISO)
biperiden  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (ISO)
bromfenac  (ISO)
bromoacetate  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
butylated hydroxyanisole  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium selenide  (ISO)
cadmium sulfate  (ISO)
Calcimycin  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
capsaicin  (EXP)
carazolol  (ISO)
carbon nanotube  (ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
carrageenan  (ISO)
ceric oxide  (EXP)
cetylpyridinium  (ISO)
CGP 52608  (ISO)
chlorobenzene  (ISO)
chlorogenic acid  (ISO)
chloropicrin  (ISO)
chloroquine  (ISO)
chlorothalonil  (ISO)
chlorpromazine  (ISO)
choline  (ISO)
cinnamyl alcohol  (ISO)
ciprofloxacin  (ISO)
cisplatin  (ISO)
citral  (ISO)
clarithromycin  (EXP,ISO)
clavulanic acid  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
clomipramine  (ISO)
clonidine  (EXP)
clonidine (amino form)  (EXP)
clonidine (imino form)  (EXP)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
cortisol  (ISO)
crocidolite asbestos  (EXP,ISO)
CU-O LINKAGE  (ISO)
curcumin  (EXP,ISO)
cycloheximide  (ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (EXP)
daidzein  (ISO)
delta-tocotrienol  (ISO)
demeclocycline  (ISO)
deoxynivalenol  (EXP,ISO)
desferrioxamine B  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (EXP,ISO)
dichloromethane  (ISO)
diclofenac  (ISO)
Didecyldimethylammonium  (ISO)
diethyl maleate  (ISO)
diethylamine  (ISO)
diethylstilbestrol  (ISO)
dimethyl sulfoxide  (ISO)
dimethylarsinous acid  (ISO)
dioxygen  (EXP,ISO)
disulfiram  (ISO)
dodecane  (ISO)
doxorubicin  (ISO)
enalapril  (ISO)
endosulfan  (EXP)
enilconazole  (ISO)
entacapone  (ISO)
entinostat  (ISO)
erlotinib hydrochloride  (ISO)
erythromycin A  (ISO)
esmolol  (ISO)
estriol  (ISO)
estrone 3-sulfate  (ISO)
ethambutol  (ISO)
ethanol  (EXP,ISO)
ethidium  (ISO)
ethionamide  (EXP)
ethylene glycol dimethacrylate  (ISO)
etodolac  (ISO)
eugenol  (ISO)
farnesol  (ISO)
ferroheme b  (ISO)
ferulic acid  (ISO)
Fexofenadine hydrochloride  (ISO)
flucloxacillin  (ISO)
fludrocortisone  (ISO)
flufenamic acid  (ISO)
fluocinolone acetonide  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
fumonisin B1  (ISO)
furan  (ISO)
gadodiamide hydrate  (EXP)
gadolinium trichloride  (EXP)
gamma-hexachlorocyclohexane  (EXP)
genistein  (ISO)
gentamycin  (EXP)
geranial  (ISO)
geraniol  (ISO)
glyoxal  (ISO)
Goe 6976  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
griseofulvin  (ISO)
heme b  (ISO)
hesperetin  (ISO)
hexadecane  (ISO)
hexadecanoic acid  (ISO)
Hexadimethrine bromide  (EXP)
hexane  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
ibuprofen  (ISO)
imidurea  (ISO)
imiquimod  (ISO)
indometacin  (EXP,ISO)
ionomycin  (ISO)
iron atom  (EXP)
iron(0)  (EXP)
iron(III) citrate  (ISO)
isoeugenol  (ISO)
isoniazide  (ISO)
isoprenaline  (EXP,ISO)
isotretinoin  (EXP)
ivermectin  (ISO)
ketoconazole  (ISO)
kojic acid  (EXP)
L-1,4-dithiothreitol  (ISO)
lead nitrate  (ISO)
lenalidomide  (ISO)
leupeptin  (ISO)
levofloxacin  (ISO)
Licochalcone B  (ISO)
limonene  (ISO)
lipoic acid  (EXP)
lipopolysaccharide  (EXP,ISO)
losartan  (EXP,ISO)
LY294002  (ISO)
m-xylene  (EXP)
manganese(II) chloride  (EXP)
mangiferin  (ISO)
mebendazole  (ISO)
melatonin  (ISO)
menadione  (EXP,ISO)
mephedrone  (EXP)
mercaptoethanol  (ISO)
mercury dichloride  (ISO)
mesalamine  (ISO)
metam  (ISO)
metaproterenol  (ISO)
methadone  (EXP)
methamphetamine  (EXP)
methapyrilene  (EXP)
methotrexate  (ISO)
methoxyacetic acid  (EXP)
methyl methacrylate  (ISO)
methyl salicylate  (ISO)
methylisothiazolinone  (ISO)
metoprolol  (ISO)
mexiletine  (ISO)
Mezerein  (ISO)
mifepristone  (ISO)
mitomycin C  (ISO)
Mofezolac (TN)  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
monocrotaline  (EXP)
morphine  (ISO)
muramyl dipeptide  (ISO)
N(gamma)-nitro-L-arginine methyl ester  (ISO)
N,N-diethyl-m-toluamide  (EXP,ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-ethylmaleimide  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
N-tosyl-L-phenylalanyl chloromethyl ketone  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
naloxone  (ISO)
naproxen  (EXP)
nebivolol  (ISO)
nefazodone  (EXP,ISO)
neocuproine  (ISO)
neoechinulin A  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
nimesulide  (ISO)
nitric oxide  (EXP,ISO)
nitrofen  (EXP)
nitrososulfamethoxazole  (ISO)
nonane  (EXP)
nonanoic acid  (ISO)
Nonidet P-40  (ISO)
Nonylphenol  (ISO)
nortriptyline  (ISO)
notoginsenoside R1  (ISO)
NS-398  (ISO)
ochratoxin A  (ISO)
octenidine  (ISO)
oleic acid  (ISO)
orciprenaline  (ISO)
Osajin  (ISO)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paliperidone palmitate  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
paricalcitol  (ISO)
parthenolide  (ISO)
pemetrexed  (ISO)
penbutolol  (ISO)
pentane-2,3-dione  (EXP)
peptidoglycan  (ISO)
perfluorododecanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenethyl caffeate  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP)
phenol  (ISO)
phloretin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphorus atom  (ISO)
phosphorus(.)  (ISO)
phthalic anhydride  (ISO)
pimecrolimus  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
polycyclic arene  (ISO)
polymyxin B2  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
potassium hydroxide  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
primaquine  (ISO)
primidone  (ISO)
probenecid  (ISO)
procyclidine  (ISO)
promethazine  (ISO)
propan-2-ol  (ISO)
prostaglandin E2  (EXP,ISO)
prostaglandin F2alpha  (ISO)
prostaglandin I2  (ISO)
pterostilbene  (ISO)
puerarin  (ISO)
Pyridostigmine bromide  (EXP,ISO)
quercetin  (ISO)
quercetin 3-O-beta-D-glucofuranoside  (EXP)
quercetin 3-O-beta-D-glucopyranoside  (EXP)
quinacrine  (ISO)
quinine  (ISO)
rac-lactic acid  (ISO)
ranitidine  (EXP)
resorcinol  (ISO)
resveratrol  (ISO)
Riluzole  (ISO)
rofecoxib  (ISO)
Roridin A  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
salicylic acid  (ISO)
SB 203580  (ISO)
SB-202190  (ISO)
SCH 23390  (EXP)
scopolamine  (ISO)
serpentine asbestos  (EXP,ISO)
silibinin  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP,ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
sodium dodecyl sulfate  (ISO)
sodium perchlorate  (EXP)
streptozocin  (ISO)
sulindac  (EXP)
sumatriptan  (EXP)
T-2 toxin  (EXP,ISO)
telithromycin  (EXP)
terameprocol  (ISO)
testosterone  (EXP,ISO)
testosterone enanthate  (EXP)
tetrachloromethane  (EXP,ISO)
tetracyclines  (ISO)
tetradecane  (ISO)
Tetramethylthiourea  (EXP)
tetraphene  (ISO)
tetrathiomolybdate(2-)  (ISO)
thioacetamide  (EXP)
thiostrepton  (ISO)
thiram  (ISO)
tienilic acid  (ISO)
titanium dioxide  (ISO)
Tolmetin glucuronide  (ISO)
toluene 2,4-diisocyanate  (ISO)
topotecan  (EXP)
toremifene  (ISO)
trans-isoeugenol  (ISO)
trazodone  (ISO)
tremolite asbestos  (ISO)
tributylstannane  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
tridecane  (ISO)
Trihexyphenidyl  (ISO)
trimethyltin  (ISO)
triptonide  (ISO)
Triton X-100  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP,ISO)
urethane  (ISO)
usnic acid  (ISO)
vadimezan  (EXP)
valproic acid  (ISO)
vanadium atom  (EXP)
vanadium(0)  (EXP)
vanadyl sulfate  (ISO)
verapamil  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
wortmannin  (ISO)
Y-27632  (EXP)
Z-Val-Phe-H  (ISO)
zidovudine  (ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (ISO)
zinc oxide  (EXP)
zinc sulfate  (ISO)
zinc(0)  (EXP,ISO)
zomepirac  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acute inflammatory response  (IEP)
cellular response to heat  (IEA,ISO,ISS)
cellular response to lipopolysaccharide  (IBA)
connective tissue replacement involved in inflammatory response wound healing  (IEA,ISO)
cytokine-mediated signaling pathway  (IBA,IEA,ISO)
ectopic germ cell programmed cell death  (IEA,ISO)
extrinsic apoptotic signaling pathway in absence of ligand  (IEA,ISO)
fever generation  (IEA)
heart development  (IEP)
immune response  (IEA)
inflammatory response  (IBA,ISO)
interleukin-1-mediated signaling pathway  (ISO)
intracellular sodium ion homeostasis  (IEA,ISO)
keratinization  (IDA)
negative regulation of cell population proliferation  (IEA,ISO)
negative regulation of establishment of Sertoli cell barrier  (IDA)
positive regulation of angiogenesis  (IEA,ISO)
positive regulation of cell division  (IEA)
positive regulation of cytokine production  (IEA,ISO)
positive regulation of ERK1 and ERK2 cascade  (IDA)
positive regulation of gene expression  (IBA,ISO)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (IDA)
positive regulation of immature T cell proliferation in thymus  (IBA)
positive regulation of interleukin-2 production  (IEA,IMP,ISO)
positive regulation of interleukin-6 production  (IMP,ISO)
positive regulation of JNK cascade  (IDA)
positive regulation of mitotic nuclear division  (IEA,ISO)
positive regulation of monocyte chemotactic protein-1 production  (ISO)
positive regulation of neutrophil extravasation  (ISO)
positive regulation of neutrophil migration  (IMP)
positive regulation of prostaglandin secretion  (IDA)
positive regulation of protein secretion  (IEA,ISO)
positive regulation of steroid biosynthetic process  (IDA)
positive regulation of stress-activated MAPK cascade  (IDA)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
positive regulation of tumor necrosis factor production  (IMP)
positive regulation of vascular endothelial growth factor production  (IEA,ISO)
regulation of actin cytoskeleton organization  (IDA)
regulation of nitric-oxide synthase activity  (IBA)
regulation of sensory perception of pain  (IDA)
response to copper ion  (IEA,ISO,ISS)
response to gamma radiation  (IEP)
response to heat  (IEP)
response to hypoxia  (IEP)
response to L-ascorbic acid  (IEP)
response to lipopolysaccharide  (IEP)
response to organic cyclic compound  (IEP)
response to organic substance  (IEP)
response to organonitrogen compound  (IEP)
response to ozone  (IEP)
signal transduction  (IEA,ISO)
spermatogenesis  (IEP)
wound healing  (IEP)

Cellular Component
cell surface  (IDA)
cytoplasm  (ISO)
cytosol  (IDA,IEA,ISO,ISS)
extracellular space  (IBA,IDA,IEA,ISO,ISS)
nucleus  (IEA)
plasma membrane  (IDA)

Molecular Function

References

References - curated
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140. Rhinovirus regulation of IL-1 receptor antagonist in vivo and in vitro: a potential mechanism of symptom resolution. Yoon HJ, etal., J Immunol. 1999 Jun 15;162(12):7461-9.
141. Interleukin-1 alpha, interleukin-1 beta, and tumor necrosis factor gene expression in endotoxin-induced uveitis. Yoshida M, etal., Invest Ophthalmol Vis Sci. 1994 Mar;35(3):1107-13.
142. Gene expression profile related to inflammation in rat model of traumatic deep vein thrombosis. Zhang CQ, etal., Chin J Traumatol. 2007 Aug;10(4):206-12.
143. Zhonghua wai ke za zhi [Chinese journal of surgery] Zhao D and Yang BX, Zhonghua Wai Ke Za Zhi. 2009 Mar 1;47(5):373-6.
144. Activated protein C improves pial microcirculation in experimental endotoxemia in rats. Zhou J, etal., Microvasc Res. 2012 May;83(3):276-80. doi: 10.1016/j.mvr.2012.03.003. Epub 2012 Mar 9.
Additional References at PubMed
PMID:1739124   PMID:2989698   PMID:3493774   PMID:9564845   PMID:10432220   PMID:11536012   PMID:12534936   PMID:12598651   PMID:12746488   PMID:12785009   PMID:12878449   PMID:14643175  
PMID:15025948   PMID:15032628   PMID:15063785   PMID:15154090   PMID:15467353   PMID:15784728   PMID:15990800   PMID:16083355   PMID:16825798   PMID:16905534   PMID:17117141   PMID:19341730  
PMID:19567205   PMID:19666510   PMID:20529813   PMID:21148126   PMID:21191089   PMID:21595923   PMID:22634325   PMID:23123184   PMID:23395675   PMID:23817958   PMID:24253784   PMID:24338227  
PMID:24338258   PMID:24644058   PMID:26002466   PMID:26899371   PMID:32920036   PMID:33106949   PMID:33107399   PMID:34047944  


Genomics

Comparative Map Data
Il1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23116,526,601 - 116,537,055 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3116,526,604 - 116,536,822 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3120,424,348 - 120,434,552 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.03129,019,955 - 129,030,165 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.03126,680,432 - 126,690,642 (-)NCBIRnor_WKY
Rnor_6.03121,824,712 - 121,836,122 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3121,825,412 - 121,836,086 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03128,180,475 - 128,190,980 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43116,913,612 - 116,924,114 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13116,819,184 - 116,829,687 (-)NCBI
Celera3115,352,857 - 115,362,929 (-)NCBICelera
Cytogenetic Map3q36NCBI
IL1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382112,773,925 - 112,784,493 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2112,773,925 - 112,784,493 (-)EnsemblGRCh38hg38GRCh38
GRCh372113,531,502 - 113,542,070 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,247,963 - 113,259,442 (-)NCBINCBI36Build 36hg18NCBI36
Build 342113,247,723 - 113,259,202NCBI
Celera2106,917,026 - 106,928,133 (-)NCBICelera
Cytogenetic Map2q14.1NCBI
HuRef2105,986,068 - 105,997,547 (-)NCBIHuRef
CHM1_12113,535,646 - 113,546,806 (-)NCBICHM1_1
T2T-CHM13v2.02113,200,569 - 113,210,953 (-)NCBIT2T-CHM13v2.0
Il1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392129,141,530 - 129,151,892 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2129,141,530 - 129,151,892 (-)EnsemblGRCm39 Ensembl
GRCm382129,299,609 - 129,310,186 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2129,299,610 - 129,309,972 (-)EnsemblGRCm38mm10GRCm38
MGSCv372129,125,346 - 129,135,708 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362128,991,051 - 129,001,413 (-)NCBIMGSCv36mm8
Celera2130,527,298 - 130,537,642 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.9NCBI
Il1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554701,527,674 - 1,538,466 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554701,527,710 - 1,538,418 (+)NCBIChiLan1.0ChiLan1.0
IL1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A113,784,854 - 113,795,801 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A113,784,854 - 113,795,801 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A89,273,482 - 89,284,421 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
IL1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11736,969,581 - 36,979,445 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1736,970,573 - 36,979,435 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1736,739,697 - 36,748,565 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01737,745,380 - 37,755,259 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1737,746,372 - 37,755,235 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11736,881,972 - 36,890,833 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01736,938,236 - 36,947,096 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01737,152,126 - 37,160,990 (-)NCBIUU_Cfam_GSD_1.0
Il1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629282,315,498 - 82,324,623 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367831,210,809 - 1,218,315 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049367831,210,715 - 1,218,315 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl343,718,368 - 43,731,119 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1343,718,320 - 43,731,668 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2345,452,989 - 45,466,307 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap3q12-q13NCBI
IL1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11415,789,710 - 15,801,938 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1415,789,013 - 15,796,611 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660803,883,451 - 3,894,101 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474912,795,946 - 12,805,154 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474912,795,967 - 12,805,658 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Il1a
60 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:778
Count of miRNA genes:262
Interacting mature miRNAs:326
Transcripts:ENSRNOT00000006113, ENSRNOT00000006126
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)3115638168135181505Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3115638168135181505Rat

Markers in Region
D3Kyo4   No map positions available.
RH129736  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23116,526,606 - 116,526,773 (+)MAPPERmRatBN7.2
Rnor_6.03121,824,715 - 121,824,881NCBIRnor6.0
Rnor_5.03128,190,811 - 128,190,977UniSTSRnor5.0
RGSC_v3.43116,913,615 - 116,913,781UniSTSRGSC3.4
Celera3115,352,860 - 115,353,026UniSTS
RH 3.4 Map3996.9UniSTS
Cytogenetic Map3q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 6 6 6 8
Low 3 11 46 31 18 31 13 10 3
Below cutoff 23 3 2 1 2 6 6 33 5 20 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000006113   ⟹   ENSRNOP00000006113
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3116,526,604 - 116,536,822 (-)Ensembl
Rnor_6.0 Ensembl3121,825,412 - 121,836,086 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000006126   ⟹   ENSRNOP00000006126
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3116,526,604 - 116,536,822 (-)Ensembl
Rnor_6.0 Ensembl3121,825,832 - 121,835,360 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000080818   ⟹   ENSRNOP00000071252
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3116,526,604 - 116,534,436 (-)Ensembl
Rnor_6.0 Ensembl3121,825,835 - 121,835,360 (-)Ensembl
RefSeq Acc Id: NM_017019   ⟹   NP_058715
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23116,526,604 - 116,536,822 (-)NCBI
Rnor_6.03121,824,712 - 121,836,122 (-)NCBI
Rnor_5.03128,180,475 - 128,190,980 (+)NCBI
RGSC_v3.43116,913,612 - 116,924,114 (-)RGD
Celera3115,352,857 - 115,362,929 (-)RGD
Sequence:
RefSeq Acc Id: XM_039104244   ⟹   XP_038960172
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23116,526,601 - 116,536,708 (-)NCBI
RefSeq Acc Id: XM_039104245   ⟹   XP_038960173
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23116,526,601 - 116,537,055 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_058715   ⟸   NM_017019
- UniProtKB: Q546R9 (UniProtKB/Swiss-Prot),   P16598 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006126   ⟸   ENSRNOT00000006126
RefSeq Acc Id: ENSRNOP00000006113   ⟸   ENSRNOT00000006113
RefSeq Acc Id: ENSRNOP00000071252   ⟸   ENSRNOT00000080818
RefSeq Acc Id: XP_038960173   ⟸   XM_039104245
- Peptide Label: isoform X2
- UniProtKB: F1MAF9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960172   ⟸   XM_039104244
- Peptide Label: isoform X1
- UniProtKB: Q546R9 (UniProtKB/Swiss-Prot)
Protein Domains
IL1_propep

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P16598-F1-model_v2 AlphaFold P16598 1-270 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692424
Promoter ID:EPDNEW_R2947
Type:single initiation site
Name:Il1a_1
Description:interleukin 1 alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03121,836,122 - 121,836,182EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2890 AgrOrtholog
BioCyc Gene G2FUF-47911 BioCyc
Ensembl Genes ENSRNOG00000004575 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000006113 ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOP00000006126 ENTREZGENE
  ENSRNOP00000006126.7 UniProtKB/TrEMBL
  ENSRNOP00000071252.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006113 ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOT00000006126 ENTREZGENE
  ENSRNOT00000006126.8 UniProtKB/TrEMBL
  ENSRNOT00000080818.2 UniProtKB/TrEMBL
InterPro IL-1_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_propep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1/FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24493 UniProtKB/Swiss-Prot
NCBI Gene 24493 ENTREZGENE
PANTHER PTHR10078 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10078:SF33 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1_propep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Il1a PhenoGen
PRINTS INTERLEUKIN1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INTRLEUKIN1A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE INTERLEUKIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50353 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K003_RAT UniProtKB/TrEMBL
  F1LQB1_RAT UniProtKB/TrEMBL
  F1MAF9 ENTREZGENE
  IL1A_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q546R9 ENTREZGENE
  Q9ESW2_RAT UniProtKB/TrEMBL
UniProt Secondary F1MAF9 UniProtKB/TrEMBL
  Q546R9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Il1a  Interleukin 1 alpha      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in tesis 729411
gene_protein may be posttranslationally modified in the testis to create alternate isoforms 729411