(+)-epicatechin-3-O-gallate multiple interactions EXP 6480464 epicatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA] CTD PMID:7665919 (-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 epigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA] CTD PMID:7665919 (-)-epigallocatechin 3-gallate decreases expression ISO IL1A (Homo sapiens) 6480464 epigallocatechin gallate results in decreased expression of IL1A mRNA CTD PMID:20706672 (-)-epigallocatechin 3-gallate multiple interactions ISO IL1A (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of IL1A mRNA CTD PMID:22079256 (E)-cinnamyl alcohol increases expression ISO IL1A (Homo sapiens) 6480464 cinnamyl alcohol results in increased expression of IL1A mRNA CTD PMID:33715048 (R)-lipoic acid multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Thioctic Acid co-treated with Propylthiouracil] results in increased expression of IL1A mRNA CTD PMID:31068541 (R,R,R)-alpha-tocopherol multiple interactions ISO Il1a (Rattus norvegicus) 6480464 alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A mRNA] and alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A protein] CTD PMID:15025948 (S)-colchicine multiple interactions ISO IL1A (Homo sapiens) 6480464 Colchicine inhibits the reaction [IL1A protein results in increased expression of VCAM1 protein] CTD PMID:11154858 (S)-nicotine multiple interactions ISO IL1A (Homo sapiens) 6480464 Nicotine results in increased expression of and results in increased secretion of IL1A protein CTD PMID:18082304 1,1'-azobis(N,N-dimethylformamide) multiple interactions ISO IL1A (Homo sapiens) 6480464 Diamide inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA] and Diamide inhibits the reaction [IL1A protein results in increased expression of SOD2 protein] CTD PMID:7476933 1,3-benzothiazole-2-thiol increases expression EXP 6480464 captax results in increased expression of IL1A protein CTD PMID:23178550 1,3-benzothiazole-2-thiol increases expression ISO IL1A (Homo sapiens) 6480464 captax results in increased expression of IL1A mRNA CTD PMID:33715048 1,3-dinitrobenzene increases expression ISO Il1a (Rattus norvegicus) 6480464 3-dinitrobenzene results in increased expression of IL1A mRNA CTD PMID:22841810 1,4-dithiothreitol multiple interactions ISO IL1A (Homo sapiens) 6480464 [Dithiothreitol co-treated with IL1A protein] results in increased expression of SOD2 protein and Dithiothreitol promotes the reaction [IL1A protein results in increased expression of SOD2 mRNA] CTD PMID:7476933 1,4-phenylenediamine increases expression EXP 6480464 4-phenylenediamine results in increased expression of IL1A protein CTD PMID:23178550 1-(alpha-Methyl-4-(2-methylpropyl)benzeneacetate)-beta-D-Glucopyranuronic acid increases expression ISO IL1A (Homo sapiens) 6480464 ibuprofen acyl glucuronide results in increased expression of IL1A mRNA CTD PMID:26528891 1-chloro-2,4-dinitrobenzene increases activity EXP 6480464 Dinitrochlorobenzene results in increased activity of IL1A protein CTD PMID:15840424 1-chloro-2,4-dinitrobenzene affects expression EXP 6480464 Dinitrochlorobenzene affects the expression of IL1A mRNA CTD PMID:28219650 1-chloro-2,4-dinitrobenzene affects secretion ISO IL1A (Homo sapiens) 6480464 Dinitrochlorobenzene affects the secretion of IL1A protein CTD PMID:12781210 1-chloro-2,4-dinitrobenzene increases expression ISO IL1A (Homo sapiens) 6480464 Dinitrochlorobenzene results in increased expression of IL1A mRNA CTD PMID:12781210 and PMID:33715048 1-chloro-2,4-dinitrobenzene multiple interactions ISO IL1A (Homo sapiens) 6480464 Dinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA] and Dinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 protein] CTD PMID:7476933 1-chloro-2,4-dinitrobenzene increases expression EXP 6480464 Dinitrochlorobenzene results in increased expression of IL1A mRNA and Dinitrochlorobenzene results in increased expression of IL1A protein CTD PMID:18652873 and PMID:23178550 1-fluoro-2,4-dinitrobenzene increases expression ISO IL1A (Homo sapiens) 6480464 Dinitrofluorobenzene results in increased expression of IL1A mRNA and Dinitrofluorobenzene results in increased expression of IL1A protein CTD PMID:12781210 and PMID:8006454 1-fluoro-2,4-dinitrobenzene affects secretion ISO IL1A (Homo sapiens) 6480464 Dinitrofluorobenzene affects the secretion of IL1A protein CTD PMID:12781210 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO Il1a (Rattus norvegicus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:22940226 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions EXP 6480464 1 more ... CTD PMID:25406165 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO Il1a (Rattus norvegicus) 6480464 guggulu extract inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:22940226 1-nitropyrene increases expression ISO IL1A (Homo sapiens) 6480464 1-nitropyrene results in increased expression of IL1A mRNA CTD PMID:19428942 and PMID:21540303 1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine increases expression ISO IL1A (Homo sapiens) 6480464 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of IL1A mRNA CTD PMID:16386258 1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester increases expression ISO IL1A (Homo sapiens) 6480464 carbetapentane results in increased expression of IL1A mRNA CTD PMID:32816093 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO IL1A (Homo sapiens) 6480464 15-deoxy-delta(12 and 14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA] CTD PMID:14998300 17alpha-ethynylestradiol increases expression ISO Il1a (Rattus norvegicus) 6480464 Ethinyl Estradiol results in increased expression of IL1A protein CTD PMID:25051504 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of IL1A mRNA CTD PMID:24781736 17beta-estradiol multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of IL1A mRNA and Estradiol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1A protein] CTD PMID:21127968 and PMID:32741896 17beta-estradiol increases expression ISO Il1a (Rattus norvegicus) 6480464 Estradiol results in increased expression of IL1A mRNA CTD PMID:32145629 17beta-estradiol multiple interactions ISO IL1A (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of IL1A mRNA more ... CTD PMID:10614622 and PMID:30165855 17beta-estradiol decreases expression ISO IL1A (Homo sapiens) 6480464 Estradiol results in decreased expression of IL1A mRNA CTD PMID:10731640 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of IL1A mRNA CTD PMID:11473722 17beta-estradiol multiple interactions EXP 6480464 daidzein inhibits the reaction [Estradiol results in increased expression of IL1A mRNA] more ... CTD PMID:11473722 and PMID:12079510 17beta-estradiol 3-benzoate multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of IL1A mRNA CTD PMID:32741896 2,2',5,5'-tetrachlorobiphenyl decreases expression ISO IL1A (Homo sapiens) 6480464 2 more ... CTD PMID:36804509 2,2'-bipyridine multiple interactions ISO IL1A (Homo sapiens) 6480464 2 and 2'-Dipyridyl inhibits the reaction [sodium arsenite results in increased expression of IL1A mRNA] CTD PMID:24570342 2,2,2-trichloroethanol increases expression ISO IL1A (Homo sapiens) 6480464 2 more ... CTD PMID:23041168 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO IL1A (Homo sapiens) 6480464 [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of IL1A mRNA CTD PMID:19684285 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Il1a (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of IL1A mRNA CTD PMID:32109520 and PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of IL1A mRNA CTD PMID:24713691 and PMID:27562557 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO IL1A (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of IL1A mRNA CTD PMID:19684285 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO IL1A (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of IL1A mRNA CTD PMID:16039398 2,3-bis(4-hydroxyphenyl)propionitrile multiple interactions ISO Il1a (Rattus norvegicus) 6480464 2 and 3-bis(4-hydroxyphenyl)-propionitrile inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1A protein] CTD PMID:21127968 2,4,6-trinitrobenzenesulfonic acid multiple interactions EXP 6480464 icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1A protein] CTD PMID:23596210 2,4,6-trinitrobenzenesulfonic acid increases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in increased expression of IL1A protein CTD PMID:23596210 2,4,6-trinitrobenzenesulfonic acid increases expression ISO IL1A (Homo sapiens) 6480464 Trinitrobenzenesulfonic Acid results in increased expression of IL1A mRNA CTD PMID:12781210 2,4-dinitrotoluene affects expression ISO Il1a (Rattus norvegicus) 6480464 2 and 4-dinitrotoluene affects the expression of IL1A mRNA CTD PMID:21346803 2,6-di-tert-butyl-4-methylphenol multiple interactions EXP 6480464 Butylated Hydroxytoluene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA] CTD PMID:8435107 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions ISO IL1A (Homo sapiens) 6480464 Verapamil inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA] CTD PMID:15613243 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine increases expression ISO IL1A (Homo sapiens) 6480464 Platelet Activating Factor results in increased expression of IL1A mRNA CTD PMID:16386258 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO Il1a (Rattus norvegicus) 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA] and IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA] CTD PMID:17109745 2-amino-2-deoxy-D-glucopyranose increases expression ISO Il1a (Rattus norvegicus) 6480464 Glucosamine results in increased expression of IL1A mRNA CTD PMID:17109745 2-hydroxypropanoic acid increases secretion ISO IL1A (Homo sapiens) 6480464 Lactic Acid results in increased secretion of IL1A protein CTD PMID:23999410 2-hydroxypropanoic acid affects expression ISO IL1A (Homo sapiens) 6480464 Lactic Acid affects the expression of IL1A mRNA CTD PMID:30851411 2-hydroxypropanoic acid increases expression EXP 6480464 Lactic Acid results in increased expression of IL1A protein CTD PMID:23178550 2-methoxy-17beta-estradiol multiple interactions ISO Il1a (Rattus norvegicus) 6480464 2-Methoxyestradiol inhibits the reaction [testosterone enanthate results in increased expression of IL1A protein] CTD PMID:30154949 2-palmitoylglycerol increases expression ISO IL1A (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of IL1A mRNA CTD PMID:37199045 2-tert-butylhydroquinone increases expression ISO IL1A (Homo sapiens) 6480464 2-tert-butylhydroquinone results in increased expression of IL1A mRNA CTD PMID:30806763 2-trans,6-trans,10-trans-geranylgeranyl diphosphate multiple interactions ISO IL1A (Homo sapiens) 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]] and geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]] CTD PMID:15728660 2-trans,6-trans,10-trans-geranylgeranyl diphosphate multiple interactions ISO Il1a (Rattus norvegicus) 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]] and geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]] CTD PMID:15705589 22-Hydroxycholesterol increases expression ISO IL1A (Homo sapiens) 6480464 22-hydroxycholesterol results in increased expression of IL1A mRNA CTD PMID:19426978 3,3',4,4',5-pentachlorobiphenyl increases expression ISO IL1A (Homo sapiens) 6480464 3 more ... CTD PMID:26519613 more ... 3,3',4,4',5-pentachlorobiphenyl affects expression EXP 6480464 3 more ... CTD PMID:37080397 3,3',4,4'-tetrachlorobiphenyl increases expression ISO IL1A (Homo sapiens) 6480464 3 more ... CTD PMID:26519613 3,3',5-triiodo-L-thyronine increases expression ISO IL1A (Homo sapiens) 6480464 Triiodothyronine results in increased expression of IL1A mRNA CTD PMID:32816093 3-acetyldeoxynivalenol multiple interactions EXP 6480464 3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL1A protein more ... CTD PMID:35413383 3-acetyldeoxynivalenol increases expression EXP 6480464 3-acetyldeoxynivalenol results in increased expression of IL1A mRNA CTD PMID:35413383 3-methylcholanthrene increases expression ISO IL1A (Homo sapiens) 6480464 Methylcholanthrene results in increased expression of IL1A mRNA CTD PMID:14993811 3-phenylprop-2-enal increases expression ISO IL1A (Homo sapiens) 6480464 cinnamaldehyde results in increased expression of IL1A mRNA CTD PMID:25290854 more ... 3-phenylprop-2-enal increases expression EXP 6480464 cinnamaldehyde results in increased expression of IL1A mRNA CTD PMID:28219650 3H-1,2-dithiole-3-thione decreases expression ISO Il1a (Rattus norvegicus) 6480464 1 and 2-dithiol-3-thione results in decreased expression of IL1A mRNA CTD PMID:19162173 4-(ethoxymethylene)-2-phenyloxazol-5-one multiple interactions EXP 6480464 Clofibrate inhibits the reaction [Oxazolone results in increased expression of IL1A protein] CTD PMID:11851881 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression ISO IL1A (Homo sapiens) 6480464 Oxazolone results in increased expression of IL1A mRNA CTD PMID:12781210 and PMID:33715048 4-(ethoxymethylene)-2-phenyloxazol-5-one affects secretion ISO IL1A (Homo sapiens) 6480464 Oxazolone affects the secretion of IL1A protein CTD PMID:12781210 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression EXP 6480464 Oxazolone results in increased expression of IL1A protein CTD PMID:11851881 and PMID:18652873 4-hydroxynon-2-enal decreases expression EXP 6480464 4-hydroxy-2-nonenal results in decreased expression of IL1A mRNA CTD PMID:19191707 4-hydroxyphenyl retinamide decreases expression EXP 6480464 Fenretinide results in decreased expression of IL1A mRNA CTD PMID:16467112 4-nitrobenzyl bromide increases expression ISO IL1A (Homo sapiens) 6480464 4-nitrobenzyl bromide results in increased expression of IL1A mRNA CTD PMID:33715048 4-octylphenol increases expression ISO IL1A (Homo sapiens) 6480464 4-octylphenol results in increased expression of IL1A protein CTD PMID:37207816 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL1A protein] and 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL1A mRNA] CTD PMID:35413383 4-tert-butylphenol multiple interactions ISO IL1A (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [butylphen results in increased expression of IL1A protein] more ... CTD PMID:28836394 4-tert-butylphenol increases expression ISO IL1A (Homo sapiens) 6480464 butylphen results in increased expression of IL1A protein CTD PMID:28836394 5-fluorouracil multiple interactions EXP 6480464 [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1A protein CTD PMID:31651976 6-propyl-2-thiouracil multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [isoquercitrin analog co-treated with Propylthiouracil] results in increased expression of IL1A mRNA and [Thioctic Acid co-treated with Propylthiouracil] results in increased expression of IL1A mRNA CTD PMID:31068541 7,12-dimethyltetraphene multiple interactions EXP 6480464 [9 more ... CTD PMID:35364107 and PMID:37352108 8-Br-cAMP multiple interactions ISO IL1A (Homo sapiens) 6480464 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]] CTD PMID:11230753 8-Br-cAMP increases expression ISO IL1A (Homo sapiens) 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IL1A mRNA CTD PMID:22079614 acetylsalicylic acid multiple interactions ISO IL1A (Homo sapiens) 6480464 [Aspirin co-treated with IL1A] results in increased expression of TNF mRNA more ... CTD PMID:14742690 acetylsalicylic acid increases expression ISO IL1A (Homo sapiens) 6480464 Aspirin results in increased expression of IL1A mRNA CTD PMID:32816093 acrylamide decreases expression ISO Il1a (Rattus norvegicus) 6480464 Acrylamide results in decreased expression of IL1A mRNA CTD PMID:28959563 actinomycin D multiple interactions ISO Il1a (Rattus norvegicus) 6480464 Dactinomycin inhibits the reaction [IL1A protein results in increased expression of FOS mRNA] CTD PMID:7564102 acyclovir increases expression ISO IL1A (Homo sapiens) 6480464 Acyclovir results in increased expression of IL1A mRNA CTD PMID:32816093 afimoxifene decreases expression ISO IL1A (Homo sapiens) 6480464 afimoxifene results in decreased expression of IL1A mRNA CTD PMID:23373633 aflatoxin B1 increases expression ISO Il1a (Rattus norvegicus) 6480464 Aflatoxin B1 results in increased expression of IL1A mRNA CTD PMID:33354967 albendazole multiple interactions ISO IL1A (Homo sapiens) 6480464 [Ivermectin co-treated with Albendazole] results in increased expression of IL1A protein CTD PMID:16861626 albuterol decreases expression ISO IL1A (Homo sapiens) 6480464 Albuterol results in decreased expression of IL1A mRNA CTD PMID:32816093 aldehydo-D-glucosamine multiple interactions ISO Il1a (Rattus norvegicus) 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA] and IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA] CTD PMID:17109745 aldehydo-D-glucosamine increases expression ISO Il1a (Rattus norvegicus) 6480464 Glucosamine results in increased expression of IL1A mRNA CTD PMID:17109745 all-trans-retinoic acid multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide more ... CTD PMID:17214633 and PMID:19362101 all-trans-retinoic acid increases expression ISO IL1A (Homo sapiens) 6480464 Tretinoin results in increased expression of IL1A mRNA CTD PMID:33167477 all-trans-retinoic acid multiple interactions EXP 6480464 Tretinoin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA] CTD PMID:8435107 all-trans-retinoic acid affects activity ISO Il1a (Rattus norvegicus) 6480464 Tretinoin affects the activity of IL1A protein CTD PMID:16847438 alpha-hexylcinnamaldehyde increases expression EXP 6480464 hexyl cinnamic aldehyde results in increased expression of IL1A protein CTD PMID:23178550 aluminium oxide increases expression ISO IL1A (Homo sapiens) 6480464 Aluminum Oxide results in increased expression of IL1A mRNA CTD PMID:15183442 amikacin decreases expression ISO IL1A (Homo sapiens) 6480464 Amikacin results in decreased expression of IL1A mRNA CTD PMID:32816093 amiodarone multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to Amiodarone CTD PMID:19362101 amiodarone increases expression ISO IL1A (Homo sapiens) 6480464 Amiodarone results in increased expression of IL1A mRNA CTD PMID:19774075 ammonium chloride affects expression ISO Il1a (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of IL1A mRNA CTD PMID:16483693 amodiaquine decreases expression ISO IL1A (Homo sapiens) 6480464 Amodiaquine results in decreased expression of IL1A mRNA CTD PMID:32816093 amphibole asbestos increases expression ISO IL1A (Homo sapiens) 6480464 Asbestos and Amphibole results in increased expression of IL1A protein CTD PMID:20855422 aniline increases expression ISO Il1a (Rattus norvegicus) 6480464 aniline results in increased expression of IL1A mRNA and aniline results in increased expression of IL1A protein CTD PMID:15694462 and PMID:18420242 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO IL1A (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [IL1A protein results in increased expression of CXCL10 mRNA] more ... CTD PMID:12832416 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO Il1a (Rattus norvegicus) 6480464 pyrazolanthrone inhibits the reaction [Soot results in increased secretion of IL1A protein] CTD PMID:19782127 anthracene-1,8,9-triol increases expression EXP 6480464 Anthralin results in increased expression of IL1A mRNA and Anthralin results in increased expression of IL1A protein CTD PMID:7665919 and PMID:8435107 anthracene-1,8,9-triol multiple interactions EXP 6480464 Plant Extracts inhibits the reaction [Anthralin results in increased expression of IL1A mRNA] and Plant Extracts inhibits the reaction [Anthralin results in increased expression of IL1A protein] CTD PMID:7665919 arachidonic acid multiple interactions EXP 6480464 [IL1A protein co-treated with Arachidonic Acid] results in increased abundance of Dinoprostone CTD PMID:11351503 aripiprazole multiple interactions ISO IL1A (Homo sapiens) 6480464 [Aripiprazole co-treated with Ozone] results in increased expression of IL1A mRNA CTD PMID:31476115 arsane increases expression ISO IL1A (Homo sapiens) 6480464 Arsenic results in increased expression of IL1A mRNA CTD PMID:19945496 and PMID:33736254 arsane multiple interactions ISO Il1a (Rattus norvegicus) 6480464 4 more ... CTD PMID:35993674 arsane multiple interactions ISO IL1A (Homo sapiens) 6480464 [Palmitic Acid co-treated with Arsenic] results in increased expression of IL1A mRNA CTD PMID:33736254 arsane decreases expression ISO IL1A (Homo sapiens) 6480464 Arsenic results in decreased expression of IL1A mRNA CTD PMID:16835338 arsenic atom increases expression ISO IL1A (Homo sapiens) 6480464 Arsenic results in increased expression of IL1A mRNA CTD PMID:19945496 and PMID:33736254 arsenic atom multiple interactions ISO Il1a (Rattus norvegicus) 6480464 4 more ... CTD PMID:35993674 arsenic atom multiple interactions ISO IL1A (Homo sapiens) 6480464 [Palmitic Acid co-treated with Arsenic] results in increased expression of IL1A mRNA CTD PMID:33736254 arsenic atom decreases expression ISO IL1A (Homo sapiens) 6480464 Arsenic results in decreased expression of IL1A mRNA CTD PMID:16835338 arsenite(3-) decreases expression ISO IL1A (Homo sapiens) 6480464 arsenite results in decreased expression of IL1A mRNA CTD PMID:16085347 arsenite(3-) multiple interactions ISO IL1A (Homo sapiens) 6480464 caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL1A mRNA] CTD PMID:16085347 arsenous acid decreases expression ISO IL1A (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of IL1A mRNA CTD PMID:17530438 arsenous acid increases expression ISO Il1a (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased expression of IL1A protein CTD PMID:33173984 arsenous acid multiple interactions ISO Il1a (Rattus norvegicus) 6480464 trans-sodium crocetinate inhibits the reaction [Arsenic Trioxide results in increased expression of IL1A protein] CTD PMID:33173984 arsenous acid affects expression ISO Il1a (Rattus norvegicus) 6480464 Arsenic Trioxide affects the expression of IL1A mRNA CTD PMID:31734849 arsenous acid increases expression ISO IL1A (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of IL1A mRNA CTD PMID:22521957 and PMID:31734849 asbestos decreases expression ISO IL1A (Homo sapiens) 6480464 Asbestos results in decreased expression of IL1A mRNA CTD PMID:22398240 asbestos increases expression ISO IL1A (Homo sapiens) 6480464 Asbestos results in increased expression of IL1A mRNA CTD PMID:22398240 ATP multiple interactions EXP 6480464 (N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2 more ... CTD PMID:26068648 azathioprine multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to Azathioprine CTD PMID:19362101 BAPTA multiple interactions EXP 6480464 1 more ... CTD PMID:9221826 benzalkonium chloride increases expression ISO IL1A (Homo sapiens) 6480464 Benzalkonium Compounds results in increased expression of IL1A mRNA and Benzalkonium Compounds results in increased expression of IL1A protein CTD PMID:12781210 more ... benzalkonium chloride increases expression EXP 6480464 Benzalkonium Compounds results in increased expression of IL1A protein CTD PMID:30517752 benzalkonium chloride multiple interactions EXP 6480464 [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1A protein CTD PMID:31158415 benzalkonium chloride increases secretion ISO IL1A (Homo sapiens) 6480464 Benzalkonium Compounds results in increased secretion of IL1A protein CTD PMID:12781210 benzatropine decreases expression ISO IL1A (Homo sapiens) 6480464 Benztropine results in decreased expression of IL1A mRNA CTD PMID:32816093 benzbromarone multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone CTD PMID:19362101 benzene affects expression ISO IL1A (Homo sapiens) 6480464 Benzene affects the expression of IL1A mRNA CTD PMID:21147609 benzene decreases response to substance EXP 6480464 IL1A protein results in decreased susceptibility to Benzene CTD PMID:1868253 benzene multiple interactions EXP 6480464 Benzene inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein] and Indomethacin inhibits the reaction [Benzene inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein]] CTD PMID:1868253 benzene decreases cleavage EXP 6480464 Benzene results in decreased cleavage of IL1A protein CTD PMID:9118901 benzene increases expression ISO Il1a (Rattus norvegicus) 6480464 Benzene results in increased expression of IL1A protein CTD PMID:15902427 benzene affects response to substance ISO IL1A (Homo sapiens) 6480464 IL1A gene SNP affects the susceptibility to Benzene CTD PMID:16230423 benzo[a]pyrene multiple interactions ISO IL1A (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Benzo(a)pyrene results in increased expression of IL1A mRNA] more ... CTD PMID:19152381 and PMID:20464547 benzo[a]pyrene increases expression ISO IL1A (Homo sapiens) 152975620 benzo[a]pyrene increases expression of IL1A mRNA in lung epithelial cell RGD benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of IL1A mRNA CTD PMID:32417428 benzo[a]pyrene increases expression ISO IL1A (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of IL1A mRNA CTD PMID:16002475 more ... benzo[a]pyrene diol epoxide I decreases expression ISO IL1A (Homo sapiens) 6480464 7 more ... CTD PMID:20018196 benzoates increases expression EXP 6480464 Benzoates results in increased expression of IL1A protein CTD PMID:23178550 benzocaine increases activity EXP 6480464 Benzocaine results in increased activity of IL1A protein CTD PMID:15840424 benzoic acid increases expression ISO IL1A (Homo sapiens) 6480464 Benzoic Acid results in increased expression of IL1A mRNA CTD PMID:12781210 benzoic acid increases secretion ISO IL1A (Homo sapiens) 6480464 Benzoic Acid results in increased secretion of IL1A protein CTD PMID:12781210 Benzoyl peroxide increases expression EXP 6480464 Benzoyl Peroxide results in increased expression of IL1A mRNA and Benzoyl Peroxide results in increased expression of IL1A protein CTD PMID:10753220 more ... Benzoyl peroxide multiple interactions EXP 6480464 Plant Extracts inhibits the reaction [Benzoyl Peroxide results in increased expression of IL1A mRNA] more ... CTD PMID:10753220 and PMID:7665919 Benzoyl peroxide increases expression ISO IL1A (Homo sapiens) 6480464 Benzoyl Peroxide results in increased expression of IL1A mRNA CTD PMID:11522381 benzyl alcohol increases expression ISO IL1A (Homo sapiens) 6480464 Benzyl Alcohol results in increased expression of IL1A protein CTD PMID:19878710 benzylpenicillin multiple interactions EXP 6480464 [Penicillin G co-treated with Erythromycin] results in increased expression of IL1A mRNA CTD PMID:27503388 benzylpenicillin increases expression EXP 6480464 Penicillin G results in increased expression of IL1A mRNA CTD PMID:27503388 beta-D-glucosamine multiple interactions ISO Il1a (Rattus norvegicus) 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA] and IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA] CTD PMID:17109745 beta-D-glucosamine increases expression ISO Il1a (Rattus norvegicus) 6480464 Glucosamine results in increased expression of IL1A mRNA CTD PMID:17109745 beta-naphthoflavone increases expression ISO IL1A (Homo sapiens) 6480464 beta-Naphthoflavone results in increased expression of IL1A mRNA CTD PMID:32151702 and PMID:8156173 beta-naphthoflavone multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA CTD PMID:21295105 biperiden increases expression ISO IL1A (Homo sapiens) 6480464 Biperiden results in increased expression of IL1A mRNA CTD PMID:32816093 bis(2-chloroethyl) sulfide increases expression ISO IL1A (Homo sapiens) 6480464 Mustard Gas results in increased expression of IL1A protein CTD PMID:8603935 bis(2-chloroethyl) sulfide increases expression ISO Il1a (Rattus norvegicus) 6480464 Mustard Gas results in increased expression of IL1A protein CTD PMID:18852015 bis(2-chloroethyl) sulfide affects expression ISO Il1a (Rattus norvegicus) 6480464 Mustard Gas affects the expression of IL1A mRNA CTD PMID:15651846 bis(2-chloroethyl) sulfide increases expression EXP 6480464 Mustard Gas results in increased expression of IL1A protein CTD PMID:11428647 bisphenol A affects expression ISO IL1A (Homo sapiens) 6480464 bisphenol A affects the expression of IL1A mRNA CTD PMID:20170705 bisphenol A increases methylation ISO Il1a (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of IL1A gene CTD PMID:28505145 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of IL1A mRNA and bisphenol A results in increased expression of IL1A protein CTD PMID:28500084 bisphenol A multiple interactions EXP 6480464 [Streptozocin co-treated with bisphenol A] results in increased expression of IL1A mRNA CTD PMID:24781736 bisphenol A affects expression ISO Il1a (Rattus norvegicus) 6480464 bisphenol A affects the expression of IL1A mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO IL1A (Homo sapiens) 6480464 bisphenol A inhibits the reaction [IL1A protein promotes the reaction [[RELA protein binds to NFKB1 protein] which binds to CCL2 promoter]] more ... CTD PMID:10614622 bleomycin A2 increases expression EXP 6480464 Bleomycin results in increased expression of IL1A protein CTD PMID:29175452 bleomycin A2 multiple interactions ISO IL1A (Homo sapiens) 6480464 IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein] more ... CTD PMID:8317554 bromfenac increases expression ISO IL1A (Homo sapiens) 6480464 bromfenac results in increased expression of IL1A mRNA CTD PMID:32816093 bromoacetate decreases expression ISO IL1A (Homo sapiens) 6480464 bromoacetate results in decreased expression of IL1A mRNA CTD PMID:19753638 bromoacetate increases expression ISO IL1A (Homo sapiens) 6480464 bromoacetate results in increased expression of IL1A mRNA CTD PMID:19753638 butan-1-ol multiple interactions ISO IL1A (Homo sapiens) 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of IL1A mRNA CTD PMID:29432896 butanal increases expression ISO IL1A (Homo sapiens) 6480464 butyraldehyde results in increased expression of IL1A mRNA CTD PMID:26079696 butylated hydroxyanisole multiple interactions EXP 6480464 Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]] and Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]] CTD PMID:18691550 cadmium atom multiple interactions ISO IL1A (Homo sapiens) 6480464 Cadmium results in increased expression of and results in increased secretion of IL1A protein CTD PMID:18082304 cadmium atom affects expression EXP 6480464 Cadmium affects the expression of IL1A mRNA CTD PMID:26363317 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL1A mRNA and Cadmium inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA] CTD PMID:26363317 and PMID:33359024 cadmium atom increases expression ISO Il1a (Rattus norvegicus) 6480464 Cadmium results in increased expression of IL1A mRNA CTD PMID:24828341 cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL1A mRNA more ... CTD PMID:33359024 and PMID:7536360 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of IL1A mRNA CTD PMID:25528414 and PMID:7536360 cadmium dichloride increases expression ISO IL1A (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of IL1A protein CTD PMID:26138014 cadmium dichloride multiple interactions ISO IL1A (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL1A protein] CTD PMID:26138014 cadmium dichloride multiple interactions ISO Il1a (Rattus norvegicus) 6480464 lipopolysaccharide and Escherichia coli O111 B4 promotes the reaction [Cadmium Chloride results in increased secretion of IL1A protein] CTD PMID:7536360 cadmium dichloride increases secretion ISO Il1a (Rattus norvegicus) 6480464 Cadmium Chloride results in increased secretion of IL1A protein CTD PMID:7536360 cadmium dichloride increases expression ISO Il1a (Rattus norvegicus) 6480464 Cadmium Chloride results in increased expression of IL1A mRNA CTD PMID:25446329 cadmium dichloride increases secretion EXP 6480464 Cadmium Chloride results in increased secretion of IL1A protein CTD PMID:7536360 cadmium selenide multiple interactions ISO IL1A (Homo sapiens) 6480464 [cadmium selenide co-treated with zinc sulfide] results in increased expression of IL1A mRNA CTD PMID:22342292 cadmium sulfate increases expression ISO IL1A (Homo sapiens) 6480464 cadmium sulfate results in increased expression of IL1A mRNA CTD PMID:12064557 and PMID:14676411 Calcimycin increases expression EXP 6480464 Calcimycin results in increased expression of IL1A mRNA CTD PMID:8435107 calcitriol decreases expression EXP 6480464 Calcitriol results in decreased expression of IL1A protein CTD PMID:2525134 Calphostin C multiple interactions ISO IL1A (Homo sapiens) 6480464 calphostin C inhibits the reaction [IL1A protein results in increased secretion of IL6 protein] CTD PMID:16532021 cannabidiol increases expression ISO IL1A (Homo sapiens) 6480464 Cannabidiol results in increased expression of IL1A mRNA CTD PMID:33244087 and PMID:36519830 cannabidiol multiple interactions EXP 6480464 [Plant Extracts results in increased abundance of Cannabidiol] which results in increased expression of IL1A mRNA CTD PMID:32400224 capsaicin multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in decreased expression of IL1A protein] more ... CTD PMID:22150557 capsaicin decreases expression ISO Il1a (Rattus norvegicus) 6480464 Capsaicin results in decreased expression of IL1A protein CTD PMID:22150557 carazolol multiple interactions ISO IL1A (Homo sapiens) 6480464 carazolol promotes the reaction [[Particulate Matter co-treated with n-hexane] results in increased expression of IL1A mRNA] CTD PMID:30503853 carbon nanotube increases expression ISO IL1A (Homo sapiens) 6480464 Nanotubes more ... CTD PMID:20800606 more ... carbon nanotube increases expression EXP 6480464 Nanotubes more ... CTD PMID:25510677 and PMID:25554681 carbon nanotube decreases expression ISO IL1A (Homo sapiens) 6480464 Nanotubes and Carbon results in decreased expression of IL1A mRNA CTD PMID:25102311 carbonyl cyanide p-trifluoromethoxyphenylhydrazone decreases expression ISO IL1A (Homo sapiens) 6480464 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of IL1A mRNA CTD PMID:16039398 carrageenan multiple interactions EXP 6480464 Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein] more ... CTD PMID:12182845 carrageenan decreases expression EXP 6480464 Carrageenan results in decreased expression of IL1A protein CTD PMID:12182845 carteolol increases expression ISO IL1A (Homo sapiens) 6480464 Carteolol results in increased expression of IL1A mRNA CTD PMID:37120125 ceric oxide increases expression ISO Il1a (Rattus norvegicus) 6480464 ceric oxide results in increased expression of IL1A mRNA CTD PMID:29463257 cetylpyridinium increases expression ISO IL1A (Homo sapiens) 6480464 Cetylpyridinium results in increased expression of IL1A protein CTD PMID:25290854 CGP 52608 multiple interactions ISO IL1A (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to IL1A gene] CTD PMID:28238834 chlorobenzene increases expression EXP 6480464 chlorobenzene results in increased expression of IL1A protein CTD PMID:23178550 chlorogenic acid decreases expression ISO IL1A (Homo sapiens) 6480464 Chlorogenic Acid results in decreased expression of IL1A mRNA CTD PMID:20706672 chloropicrin affects expression ISO IL1A (Homo sapiens) 6480464 chloropicrin affects the expression of IL1A mRNA CTD PMID:26352163 chloroquine increases expression ISO IL1A (Homo sapiens) 6480464 Chloroquine results in increased expression of IL1A CTD PMID:15139008 chloroquine multiple interactions EXP 6480464 Chloroquine inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased secretion of IL1A protein] CTD PMID:22341560 chlorothalonil increases expression ISO IL1A (Homo sapiens) 6480464 tetrachloroisophthalonitrile metabolite results in increased expression of IL1A mRNA CTD PMID:32289622 chlorpromazine multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to Chlorpromazine CTD PMID:19362101 choline multiple interactions EXP 6480464 [Dietary Fats co-treated with Choline deficiency] results in increased expression of IL1A protein and PANX1 gene mutant form inhibits the reaction [[Dietary Fats co-treated with Choline deficiency] results in increased expression of IL1A protein] CTD PMID:29246445 cinnamyl alcohol increases expression ISO IL1A (Homo sapiens) 6480464 cinnamyl alcohol results in increased expression of IL1A mRNA CTD PMID:33715048 ciprofloxacin multiple interactions ISO IL1A (Homo sapiens) 6480464 Ciprofloxacin inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide] and wortmannin inhibits the reaction [Ciprofloxacin inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]] CTD PMID:16968468 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of IL1A mRNA and Cisplatin results in increased expression of IL1A protein CTD PMID:20844023 and PMID:26546572 cisplatin multiple interactions EXP 6480464 Cisplatin inhibits the reaction [[9 more ... CTD PMID:37352108 citral increases expression EXP 6480464 citral results in increased expression of IL1A protein CTD PMID:23178550 clarithromycin multiple interactions ISO IL1A (Homo sapiens) 6480464 [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide more ... CTD PMID:19362101 clarithromycin multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to Clarithromycin CTD PMID:19362101 clavulanic acid increases expression ISO IL1A (Homo sapiens) 6480464 Clavulanic Acid results in increased expression of IL1A mRNA CTD PMID:32816093 clobetasol decreases secretion EXP 6480464 Clobetasol results in decreased secretion of IL1A protein CTD PMID:15086553 clofibrate multiple interactions EXP 6480464 Clofibrate inhibits the reaction [Oxazolone results in increased expression of IL1A protein] and Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A protein] CTD PMID:11851881 clomipramine multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to Clomipramine CTD PMID:19362101 clonidine multiple interactions ISO Il1a (Rattus norvegicus) 6480464 BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein]] and Clonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein] CTD PMID:16192389 clonidine (amino form) multiple interactions ISO Il1a (Rattus norvegicus) 6480464 BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein]] and Clonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein] CTD PMID:16192389 clonidine (imino form) multiple interactions ISO Il1a (Rattus norvegicus) 6480464 BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein]] and Clonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein] CTD PMID:16192389 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of IL1A protein CTD PMID:23178550 cocaine affects expression ISO Il1a (Rattus norvegicus) 6480464 Cocaine affects the expression of IL1A mRNA CTD PMID:20187946 copper atom multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Iron co-treated with Diethylnitrosamine co-treated with Copper] results in increased expression of IL1A mRNA CTD PMID:20302851 copper atom multiple interactions ISO IL1A (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of IL1A mRNA and [Disulfiram binds to Copper] which results in increased expression of IL1A mRNA CTD PMID:24690739 and PMID:30911355 copper atom increases secretion ISO Il1a (Rattus norvegicus) 6480464 Copper results in increased secretion of IL1A protein CTD PMID:19635393 copper atom increases secretion EXP 6480464 Copper results in increased secretion of IL1A protein CTD PMID:19635393 copper(0) multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Iron co-treated with Diethylnitrosamine co-treated with Copper] results in increased expression of IL1A mRNA CTD PMID:20302851 copper(0) multiple interactions ISO IL1A (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of IL1A mRNA and [Disulfiram binds to Copper] which results in increased expression of IL1A mRNA CTD PMID:24690739 and PMID:30911355 copper(0) increases secretion ISO Il1a (Rattus norvegicus) 6480464 Copper results in increased secretion of IL1A protein CTD PMID:19635393 copper(0) increases secretion EXP 6480464 Copper results in increased secretion of IL1A protein CTD PMID:19635393 copper(II) chloride increases secretion ISO IL1A (Homo sapiens) 6480464 cupric chloride results in increased secretion of IL1A protein CTD PMID:22954531 corn oil increases secretion ISO Il1a (Rattus norvegicus) 6480464 Corn Oil results in increased secretion of IL1A protein CTD PMID:33263755 cortisol decreases expression ISO IL1A (Homo sapiens) 6480464 Hydrocortisone results in decreased expression of IL1A mRNA CTD PMID:21980503 cortisol multiple interactions ISO IL1A (Homo sapiens) 6480464 Hydrocortisone inhibits the reaction [IL1A protein results in increased activity of MMP9 protein] more ... CTD PMID:18722610 crocidolite asbestos increases expression ISO IL1A (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased expression of IL1A mRNA CTD PMID:24160326 and PMID:25757056 crocidolite asbestos increases expression EXP 6480464 Asbestos and Crocidolite results in increased expression of IL1A protein CTD PMID:29279043 crocidolite asbestos increases expression ISO Il1a (Rattus norvegicus) 6480464 Asbestos and Crocidolite results in increased expression of IL1A mRNA CTD PMID:7539275 crocidolite asbestos multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Asbestos more ... CTD PMID:7539275 and PMID:9400719 CU-O LINKAGE multiple interactions ISO IL1A (Homo sapiens) 6480464 cupric oxide results in increased expression of and results in increased secretion of IL1A protein CTD PMID:22954531 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [IL1A protein results in increased expression of TNFSF11 protein] CTD PMID:18719352 curcumin multiple interactions ISO Il1a (Rattus norvegicus) 6480464 Curcumin inhibits the reaction [Soot results in increased secretion of IL1A protein] CTD PMID:19782127 cycloheximide multiple interactions ISO IL1A (Homo sapiens) 6480464 [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of IL1A mRNA CTD PMID:19684285 cycloheximide increases expression ISO IL1A (Homo sapiens) 6480464 Cycloheximide results in increased expression of IL1A mRNA CTD PMID:19684285 cyclophosphamide increases expression EXP 6480464 Cyclophosphamide results in increased expression of IL1A mRNA CTD PMID:15331540 cyclophosphamide multiple interactions EXP 6480464 [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1A protein CTD PMID:31651976 cyclophosphamide increases expression ISO Il1a (Rattus norvegicus) 6480464 Cyclophosphamide results in increased expression of IL1A protein CTD PMID:18848347 cyclophosphamide affects response to substance ISO IL1A (Homo sapiens) 6480464 IL1A promoter polymorphism affects the susceptibility to Cyclophosphamide CTD PMID:16636934 cyclosporin A decreases expression ISO Il1a (Rattus norvegicus) 6480464 Cyclosporine results in decreased expression of IL1A protein CTD PMID:25051504 cytochalasin D multiple interactions EXP 6480464 Cytochalasin D inhibits the reaction [Quartz results in increased import of IL1A protein] and Cytochalasin D promotes the reaction [Quartz results in increased secretion of IL1A protein] CTD PMID:36840754 daidzein multiple interactions EXP 6480464 daidzein inhibits the reaction [Estradiol results in increased expression of IL1A mRNA] CTD PMID:11473722 delta-tocotrienol increases expression EXP 6480464 tocotrienol and delta results in increased expression of IL1A mRNA CTD PMID:22185406 demeclocycline multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to Demeclocycline CTD PMID:19362101 deoxynivalenol increases expression ISO Il1a (Rattus norvegicus) 6480464 deoxynivalenol results in increased expression of IL1A mRNA CTD PMID:32738333 deoxynivalenol multiple interactions EXP 6480464 Fatty Acids more ... CTD PMID:15681167 and PMID:16009389 deoxynivalenol increases expression EXP 6480464 deoxynivalenol results in increased expression of IL1A mRNA CTD PMID:15371230 more ... desferrioxamine B multiple interactions ISO IL1A (Homo sapiens) 6480464 Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA] CTD PMID:21703343 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]] more ... CTD PMID:12182845 more ... dexamethasone multiple interactions ISO IL1A (Homo sapiens) 6480464 Dexamethasone inhibits the reaction [IL1A protein results in increased expression of PTGS1 mRNA] more ... CTD PMID:15167967 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of IL1A mRNA CTD PMID:22185406 dextran sulfate multiple interactions EXP 6480464 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester inhibits the reaction [Dextran Sulfate results in increased expression of IL1A protein] more ... CTD PMID:25472953 more ... dextran sulfate increases expression EXP 6480464 Dextran Sulfate results in increased expression of IL1A mRNA and Dextran Sulfate results in increased expression of IL1A protein CTD PMID:23894361 more ... diarsenic trioxide decreases expression ISO IL1A (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of IL1A mRNA CTD PMID:17530438 diarsenic trioxide multiple interactions ISO Il1a (Rattus norvegicus) 6480464 trans-sodium crocetinate inhibits the reaction [Arsenic Trioxide results in increased expression of IL1A protein] CTD PMID:33173984 diarsenic trioxide increases expression ISO Il1a (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased expression of IL1A protein CTD PMID:33173984 diarsenic trioxide affects expression ISO Il1a (Rattus norvegicus) 6480464 Arsenic Trioxide affects the expression of IL1A mRNA CTD PMID:31734849 diarsenic trioxide increases expression ISO IL1A (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of IL1A mRNA CTD PMID:22521957 and PMID:31734849 dichloromethane multiple interactions ISO IL1A (Homo sapiens) 6480464 [Particulate Matter co-treated with Methylene Chloride] results in increased expression of IL1A mRNA CTD PMID:30503853 diclofenac multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to Diclofenac CTD PMID:19362101 diclofenac increases expression ISO IL1A (Homo sapiens) 6480464 Diclofenac results in increased expression of IL1A mRNA CTD PMID:32816093 Didecyldimethylammonium increases expression ISO IL1A (Homo sapiens) 6480464 didecyldimethylammonium results in increased expression of IL1A mRNA CTD PMID:32763356 diethyl maleate multiple interactions ISO IL1A (Homo sapiens) 6480464 diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA] and diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 protein] CTD PMID:7476933 diethylamine increases activity EXP 6480464 diethylamine results in increased activity of IL1A protein CTD PMID:15840424 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of IL1A mRNA and Diethylstilbestrol results in increased expression of IL1A protein CTD PMID:15171707 and PMID:15794588 dimethyl sulfoxide multiple interactions ISO IL1A (Homo sapiens) 6480464 Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA] CTD PMID:21878375 dimethylarsinous acid increases expression ISO IL1A (Homo sapiens) 6480464 dimethylarsinous acid results in increased expression of IL1A mRNA CTD PMID:23487506 dimethylarsinous acid decreases expression ISO IL1A (Homo sapiens) 6480464 dimethylarsinous acid results in decreased expression of IL1A mRNA CTD PMID:19945496 dioxygen increases expression ISO IL1A (Homo sapiens) 6480464 Oxygen results in increased expression of IL1A mRNA and Oxygen results in increased expression of IL1A protein CTD PMID:24024155 dioxygen multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of and results in increased secretion of IL1A protein] and [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of and results in increased secretion of IL1A protein CTD PMID:33729688 dioxygen decreases expression ISO IL1A (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of IL1A protein CTD PMID:8702551 dioxygen multiple interactions ISO IL1A (Homo sapiens) 6480464 Oxygen deficiency inhibits the reaction [TNF protein results in increased expression of IL1A protein] more ... CTD PMID:24024155 and PMID:8702551 disulfiram multiple interactions ISO IL1A (Homo sapiens) 6480464 [Disulfiram binds to Copper] which results in increased expression of IL1A mRNA CTD PMID:24690739 dodecane multiple interactions ISO IL1A (Homo sapiens) 6480464 n-dodecane results in increased expression of and results in increased secretion of IL1A protein CTD PMID:19720135 doxorubicin multiple interactions ISO IL1A (Homo sapiens) 6480464 IL1A protein promotes the reaction [Doxorubicin results in increased expression of CAT protein] more ... CTD PMID:8317554 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of IL1A protein CTD PMID:35667395 doxorubicin decreases expression ISO IL1A (Homo sapiens) 6480464 Doxorubicin results in decreased expression of IL1A mRNA CTD PMID:29803840 edaravone multiple interactions EXP 6480464 Edaravone inhibits the reaction [Thioacetamide results in increased expression of IL1A mRNA] CTD PMID:36343683 enalapril multiple interactions ISO IL1A (Homo sapiens) 6480464 Enalapril inhibits the reaction [IL1A protein results in increased expression of VEGFA mRNA] and Enalapril inhibits the reaction [IL1A protein results in increased expression of VEGFA protein] CTD PMID:17299153 endosulfan increases expression ISO Il1a (Rattus norvegicus) 6480464 Endosulfan results in increased expression of IL1A mRNA CTD PMID:29391264 enilconazole increases expression EXP 6480464 enilconazole results in increased expression of IL1A mRNA CTD PMID:32814239 entacapone increases expression ISO IL1A (Homo sapiens) 6480464 entacapone results in increased expression of IL1A mRNA CTD PMID:32816093 entinostat increases expression ISO IL1A (Homo sapiens) 6480464 entinostat results in increased expression of IL1A mRNA CTD PMID:27188386 erlotinib hydrochloride multiple interactions ISO IL1A (Homo sapiens) 6480464 [Erlotinib Hydrochloride results in decreased susceptibility to Erlotinib Hydrochloride] which results in increased expression of IL1A mRNA CTD PMID:27738319 erythromycin A increases expression EXP 6480464 Erythromycin results in increased expression of IL1A mRNA CTD PMID:27503388 erythromycin A multiple interactions EXP 6480464 [Penicillin G co-treated with Erythromycin] results in increased expression of IL1A mRNA CTD PMID:27503388 esmolol increases expression ISO IL1A (Homo sapiens) 6480464 esmolol results in increased expression of IL1A mRNA CTD PMID:32816093 estriol decreases expression ISO IL1A (Homo sapiens) 6480464 Estriol results in decreased expression of IL1A mRNA CTD PMID:10731640 estrone 3-sulfate decreases expression ISO IL1A (Homo sapiens) 6480464 estrone sulfate results in decreased expression of IL1A mRNA CTD PMID:10731640 ethambutol increases expression ISO IL1A (Homo sapiens) 6480464 Ethambutol results in increased expression of IL1A mRNA CTD PMID:32816093 ethanol increases expression EXP 6480464 Ethanol results in increased expression of IL1A mRNA and Ethanol results in increased expression of IL1A protein CTD PMID:28843478 more ... ethanol multiple interactions EXP 6480464 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1A mRNA]] more ... CTD PMID:34192554 and PMID:34405320 ethanol increases expression ISO Il1a (Rattus norvegicus) 6480464 Ethanol results in increased expression of IL1A mRNA CTD PMID:35227807 ethanol decreases expression ISO IL1A (Homo sapiens) 6480464 Ethanol results in decreased expression of IL1A mRNA CTD PMID:28964808 ethanol multiple interactions ISO IL1A (Homo sapiens) 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of IL1A mRNA more ... CTD PMID:28964808 more ... ethidium multiple interactions EXP 6480464 Ethidium inhibits the reaction [sodium arsenate results in increased expression of IL1A protein] and Ethidium inhibits the reaction [tributyltin results in increased expression of IL1A protein] CTD PMID:10571731 and PMID:8875956 ethionamide increases expression ISO Il1a (Rattus norvegicus) 6480464 Ethionamide results in increased expression of IL1A protein CTD PMID:25051504 ethylene glycol dimethacrylate increases expression EXP 6480464 ethylene dimethacrylate results in increased expression of IL1A protein CTD PMID:23178550 etodolac increases expression ISO IL1A (Homo sapiens) 6480464 Etodolac results in increased expression of IL1A mRNA CTD PMID:32816093 eugenol increases expression ISO IL1A (Homo sapiens) 6480464 Eugenol results in increased expression of IL1A mRNA CTD PMID:30806763 and PMID:33715048 farnesol increases expression ISO IL1A (Homo sapiens) 6480464 Farnesol results in increased expression of IL1A mRNA CTD PMID:30806763 ferroheme b increases expression EXP 6480464 Heme metabolite results in increased expression of IL1A mRNA CTD PMID:19191707 ferulic acid multiple interactions EXP 6480464 ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL1A mRNA] CTD PMID:31054998 Fexofenadine hydrochloride multiple interactions EXP 6480464 [fexofenadine co-treated with Dietary Fats co-treated with APOE gene mutant form] results in decreased expression of IL1A protein CTD PMID:25020133 Fexofenadine hydrochloride decreases expression ISO IL1A (Homo sapiens) 6480464 fexofenadine results in decreased expression of IL1A mRNA CTD PMID:32816093 flucloxacillin increases secretion ISO IL1A (Homo sapiens) 6480464 Floxacillin results in increased secretion of IL1A protein CTD PMID:28444390 fludrocortisone decreases expression ISO IL1A (Homo sapiens) 6480464 Fludrocortisone results in decreased expression of IL1A mRNA CTD PMID:32816093 flufenamic acid multiple interactions ISO IL1A (Homo sapiens) 6480464 Flufenamic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein] CTD PMID:10866999 fluocinolone acetonide multiple interactions EXP 6480464 Fluocinolone Acetonide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA] CTD PMID:8435107 folic acid multiple interactions ISO IL1A (Homo sapiens) 6480464 [Folic Acid affects the susceptibility to Pemetrexed] which affects the expression of IL1A mRNA and [Folic Acid deficiency co-treated with Methotrexate] results in increased expression of IL1A mRNA CTD PMID:22975265 and PMID:24657277 formaldehyde multiple interactions ISO IL1A (Homo sapiens) 6480464 Formaldehyde results in increased expression of and results in increased secretion of IL1A protein CTD PMID:18082304 fulvestrant multiple interactions ISO IL1A (Homo sapiens) 6480464 fulvestrant inhibits the reaction [bisphenol A inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]] more ... CTD PMID:10614622 fumonisin B1 increases expression EXP 6480464 fumonisin B1 results in increased expression of IL1A mRNA CTD PMID:17080400 furan decreases expression EXP 6480464 furan results in decreased expression of IL1A mRNA CTD PMID:20194422 gadodiamide hydrate increases expression ISO Il1a (Rattus norvegicus) 6480464 gadodiamide results in increased expression of IL1A protein CTD PMID:20938346 gadolinium trichloride multiple interactions ISO Il1a (Rattus norvegicus) 6480464 gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A mRNA] and gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A protein] CTD PMID:15025948 gamma-hexachlorocyclohexane multiple interactions ISO Il1a (Rattus norvegicus) 6480464 alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A mRNA] more ... CTD PMID:15025948 gamma-hexachlorocyclohexane increases expression ISO Il1a (Rattus norvegicus) 6480464 Hexachlorocyclohexane results in increased expression of IL1A mRNA and Hexachlorocyclohexane results in increased expression of IL1A protein CTD PMID:15025948 gemcitabine decreases expression ISO IL1A (Homo sapiens) 6480464 Gemcitabine results in decreased expression of IL1A protein CTD PMID:20531411 genistein multiple interactions EXP 6480464 Genistein inhibits the reaction [Estradiol results in increased expression of IL1A mRNA] CTD PMID:11473722 genistein decreases expression ISO IL1A (Homo sapiens) 6480464 Genistein results in decreased expression of IL1A mRNA CTD PMID:20706672 gentamycin decreases expression ISO Il1a (Rattus norvegicus) 6480464 Gentamicins results in decreased expression of IL1A protein CTD PMID:25051504 gentamycin increases expression ISO Il1a (Rattus norvegicus) 6480464 Gentamicins results in increased expression of IL1A mRNA CTD PMID:33387578 geranial increases expression EXP 6480464 citral results in increased expression of IL1A protein CTD PMID:23178550 geraniol increases expression ISO IL1A (Homo sapiens) 6480464 geraniol results in increased expression of IL1A protein CTD PMID:19878710 glyoxal increases expression ISO IL1A (Homo sapiens) 6480464 Glyoxal results in increased expression of IL1A mRNA CTD PMID:33715048 Goe 6976 multiple interactions ISO IL1A (Homo sapiens) 6480464 Go 6976 inhibits the reaction [IL1A protein results in increased secretion of IL6 protein] CTD PMID:16532021 gold atom multiple interactions EXP 6480464 [Gold co-treated with Silicon Dioxide] results in increased secretion of IL1A protein CTD PMID:22155353 gold atom decreases expression ISO IL1A (Homo sapiens) 6480464 Gold analog results in decreased expression of IL1A mRNA CTD PMID:36057382 gold atom increases secretion EXP 6480464 Gold results in increased secretion of IL1A protein CTD PMID:22155353 gold(0) multiple interactions EXP 6480464 [Gold co-treated with Silicon Dioxide] results in increased secretion of IL1A protein CTD PMID:22155353 gold(0) decreases expression ISO IL1A (Homo sapiens) 6480464 Gold analog results in decreased expression of IL1A mRNA CTD PMID:36057382 gold(0) increases secretion EXP 6480464 Gold results in increased secretion of IL1A protein CTD PMID:22155353 griseofulvin multiple interactions ISO IL1A (Homo sapiens) 6480464 Griseofulvin inhibits the reaction [IL1A protein results in increased expression of VCAM1 protein] CTD PMID:11367519 heme b increases expression EXP 6480464 Heme metabolite results in increased expression of IL1A mRNA CTD PMID:19191707 hesperetin multiple interactions ISO IL1A (Homo sapiens) 6480464 hesperetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein] CTD PMID:24707119 hexadecane multiple interactions ISO IL1A (Homo sapiens) 6480464 n-hexadecane results in increased expression of and results in increased secretion of IL1A protein CTD PMID:19720135 hexadecanoic acid multiple interactions ISO IL1A (Homo sapiens) 6480464 [Palmitic Acid co-treated with Arsenic] results in increased expression of IL1A mRNA more ... CTD PMID:30547786 and PMID:33736254 Hexadimethrine bromide multiple interactions ISO Il1a (Rattus norvegicus) 6480464 Hexadimethrine Bromide inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of IL1A mRNA] CTD PMID:32157350 hexane multiple interactions ISO IL1A (Homo sapiens) 6480464 [Particulate Matter co-treated with n-hexane] results in increased expression of IL1A mRNA and carazolol promotes the reaction [[Particulate Matter co-treated with n-hexane] results in increased expression of IL1A mRNA] CTD PMID:30503853 hydrogen peroxide increases expression ISO IL1A (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of IL1A mRNA and Hydrogen Peroxide results in increased expression of IL1A protein CTD PMID:11378323 more ... hydrogen peroxide multiple interactions ISO IL1A (Homo sapiens) 6480464 gentian root extract inhibits the reaction [Hydrogen Peroxide results in increased expression of IL1A protein] CTD PMID:37894611 hydrogen peroxide decreases expression ISO IL1A (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased expression of IL1A mRNA CTD PMID:26339600 hydroquinone multiple interactions EXP 6480464 hydroquinone inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein] CTD PMID:1868253 hydroquinone multiple interactions ISO IL1A (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of IL1A protein] more ... CTD PMID:28836394 hydroquinone increases expression ISO IL1A (Homo sapiens) 6480464 hydroquinone results in increased expression of IL1A mRNA and hydroquinone results in increased expression of IL1A protein CTD PMID:28836394 and PMID:31256213 hydroquinone decreases cleavage EXP 6480464 hydroquinone results in decreased cleavage of IL1A protein CTD PMID:8548860 and PMID:9118901 ibuprofen multiple interactions ISO IL1A (Homo sapiens) 6480464 Ibuprofen inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein] CTD PMID:11230753 ibuprofen increases expression ISO IL1A (Homo sapiens) 6480464 Ibuprofen results in increased expression of IL1A mRNA CTD PMID:17070997 imidurea increases expression EXP 6480464 imidazolidinyl urea results in increased expression of IL1A protein CTD PMID:23178550 imiquimod increases expression EXP 6480464 Imiquimod results in increased expression of IL1A mRNA CTD PMID:31054998 imiquimod multiple interactions EXP 6480464 ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL1A mRNA] CTD PMID:31054998 indometacin increases expression ISO Il1a (Rattus norvegicus) 6480464 Indomethacin results in increased expression of IL1A protein CTD PMID:25051504 indometacin multiple interactions EXP 6480464 Indomethacin inhibits the reaction [Benzene inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein]] CTD PMID:1868253 indometacin multiple interactions ISO IL1A (Homo sapiens) 6480464 Indomethacin inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein] CTD PMID:11230753 ionomycin multiple interactions ISO IL1A (Homo sapiens) 6480464 [Ionomycin co-treated with IL1A protein] results in decreased secretion of IL4 protein more ... CTD PMID:10820229 iron atom multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Iron co-treated with Diethylnitrosamine co-treated with Copper] results in increased expression of IL1A mRNA and [Iron co-treated with Diethylnitrosamine] results in increased expression of IL1A mRNA CTD PMID:20302851 iron(0) multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Iron co-treated with Diethylnitrosamine co-treated with Copper] results in increased expression of IL1A mRNA and [Iron co-treated with Diethylnitrosamine] results in increased expression of IL1A mRNA CTD PMID:20302851 iron(III) citrate decreases expression ISO IL1A (Homo sapiens) 6480464 ferric citrate results in decreased expression of IL1A mRNA CTD PMID:29959986 isoeugenol increases expression EXP 6480464 isoeugenol results in increased expression of IL1A protein CTD PMID:23178550 isoniazide increases secretion ISO IL1A (Homo sapiens) 6480464 Isoniazid results in increased secretion of IL1A protein CTD PMID:28444390 isoniazide increases expression ISO IL1A (Homo sapiens) 6480464 Isoniazid results in increased expression of IL1A mRNA CTD PMID:32816093 isoprenaline decreases expression ISO IL1A (Homo sapiens) 6480464 Isoproterenol results in decreased expression of IL1A mRNA CTD PMID:24286936 and PMID:32816093 isoprenaline increases expression ISO Il1a (Rattus norvegicus) 6480464 Isoproterenol results in increased expression of IL1A mRNA CTD PMID:24286936 isoprenaline decreases expression ISO Il1a (Rattus norvegicus) 6480464 Isoproterenol results in decreased expression of IL1A mRNA CTD PMID:24286936 isoprenaline increases expression ISO IL1A (Homo sapiens) 6480464 Isoproterenol results in increased expression of IL1A mRNA CTD PMID:24286936 isotretinoin decreases secretion ISO Il1a (Rattus norvegicus) 6480464 Isotretinoin results in decreased secretion of IL1A protein CTD PMID:15972972 ivermectin multiple interactions ISO IL1A (Homo sapiens) 6480464 [Ivermectin co-treated with Albendazole] results in increased expression of IL1A protein CTD PMID:16861626 ketoconazole increases expression ISO IL1A (Homo sapiens) 6480464 Ketoconazole results in increased expression of IL1A mRNA CTD PMID:32816093 kojic acid multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with kojic acid] results in decreased expression of IL1A mRNA CTD PMID:18544905 L-1,4-dithiothreitol multiple interactions ISO IL1A (Homo sapiens) 6480464 [Dithiothreitol co-treated with IL1A protein] results in increased expression of SOD2 protein and Dithiothreitol promotes the reaction [IL1A protein results in increased expression of SOD2 mRNA] CTD PMID:7476933 lead nitrate multiple interactions EXP 6480464 [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in decreased expression of CYP7A1 mRNA] more ... CTD PMID:22293356 lead nitrate increases expression EXP 6480464 lead nitrate results in increased expression of IL1A mRNA CTD PMID:22293356 lenalidomide multiple interactions EXP 6480464 lenalidomide inhibits the reaction [SOD1 gene mutant form results in increased expression of IL1A mRNA] CTD PMID:16510725 leupeptin multiple interactions ISO IL1A (Homo sapiens) 6480464 leupeptin inhibits the reaction [Particulate Matter results in increased secretion of IL1A protein] CTD PMID:21818627 levofloxacin increases expression ISO IL1A (Homo sapiens) 6480464 Levofloxacin results in increased expression of IL1A mRNA CTD PMID:32816093 Licochalcone B decreases expression ISO IL1A (Homo sapiens) 6480464 licochalcone B results in decreased expression of IL1A mRNA CTD PMID:33647349 limonene affects expression ISO IL1A (Homo sapiens) 6480464 Limonene affects the expression of IL1A protein CTD PMID:19878710 lipoic acid multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Thioctic Acid co-treated with Propylthiouracil] results in increased expression of IL1A mRNA CTD PMID:31068541 lipopolysaccharide multiple interactions ISO IL1A (Homo sapiens) 6480464 15-deoxyprostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein] more ... CTD PMID:10866999 more ... lipopolysaccharide affects secretion EXP 6480464 Lipopolysaccharides affects the secretion of IL1A protein CTD PMID:30301768 lipopolysaccharide decreases expression ISO IL1A (Homo sapiens) 6480464 Lipopolysaccharides results in decreased expression of IL1A mRNA CTD PMID:28964808 lipopolysaccharide increases secretion ISO Il1a (Rattus norvegicus) 6480464 Lipopolysaccharides results in increased secretion of IL1A protein CTD PMID:21127968 and PMID:21504754 lipopolysaccharide increases expression ISO Il1a (Rattus norvegicus) 6480464 Lipopolysaccharides results in increased expression of IL1A protein CTD PMID:21362633 lipopolysaccharide increases secretion ISO IL1A (Homo sapiens) 6480464 Lipopolysaccharides results in increased secretion of IL1A protein CTD PMID:20005085 and PMID:32800949 lipopolysaccharide increases expression ISO IL1A (Homo sapiens) 6480464 Lipopolysaccharides results in increased expression of IL1A mRNA and Lipopolysaccharides results in increased expression of IL1A protein CTD PMID:10866999 more ... lipopolysaccharide multiple interactions ISO Il1a (Rattus norvegicus) 6480464 2 more ... CTD PMID:16192389 more ... lipopolysaccharide increases secretion EXP 6480464 Lipopolysaccharides results in increased secretion of IL1A protein CTD PMID:26582142 and PMID:32800949 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of IL1A mRNA and Lipopolysaccharides results in increased expression of IL1A protein CTD PMID:15371095 more ... lipopolysaccharide increases cleavage EXP 6480464 Lipopolysaccharides results in increased cleavage of IL1A protein CTD PMID:1868253 lipopolysaccharide multiple interactions EXP 6480464 (+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA] more ... CTD PMID:15804595 more ... losartan multiple interactions ISO IL1A (Homo sapiens) 6480464 Losartan inhibits the reaction [IL1A protein results in increased expression of VEGFA mRNA] and Losartan inhibits the reaction [IL1A protein results in increased expression of VEGFA protein] CTD PMID:17299153 losartan decreases expression ISO Il1a (Rattus norvegicus) 6480464 Losartan results in decreased expression of IL1A protein CTD PMID:23875703 LY294002 multiple interactions ISO IL1A (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IL1A protein results in increased expression of BDKRB1 protein] CTD PMID:29775649 m-xylene increases expression ISO Il1a (Rattus norvegicus) 6480464 3-xylene results in increased expression of IL1A protein CTD PMID:12717741 and PMID:15902427 malathion increases expression ISO IL1A (Homo sapiens) 6480464 Malathion results in increased expression of IL1A mRNA CTD PMID:37047231 manganese(II) chloride increases expression ISO Il1a (Rattus norvegicus) 6480464 manganese chloride results in increased expression of IL1A mRNA CTD PMID:25219578 mangiferin decreases expression EXP 6480464 mangiferin results in decreased expression of IL1A mRNA CTD PMID:15135318 mebendazole increases expression ISO IL1A (Homo sapiens) 6480464 Mebendazole results in increased expression of IL1A mRNA CTD PMID:32816093 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Dextran Sulfate results in increased expression of IL1A protein] and Melatonin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA] CTD PMID:21461237 and PMID:36265525 melatonin decreases expression EXP 6480464 Melatonin results in decreased expression of IL1A mRNA CTD PMID:21461237 menadione multiple interactions ISO Il1a (Rattus norvegicus) 6480464 Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of IL1A mRNA] and Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of IL1A protein] CTD PMID:19265712 menadione multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to Vitamin K 3 CTD PMID:19362101 menadione increases secretion ISO Il1a (Rattus norvegicus) 6480464 Vitamin K 3 results in increased secretion of IL1A protein CTD PMID:19265712 menadione increases expression ISO Il1a (Rattus norvegicus) 6480464 Vitamin K 3 results in increased expression of IL1A mRNA CTD PMID:19265712 mephedrone affects expression ISO Il1a (Rattus norvegicus) 6480464 mephedrone affects the expression of IL1A protein CTD PMID:34742947 mercaptoethanol multiple interactions ISO IL1A (Homo sapiens) 6480464 [Mercaptoethanol co-treated with IL1A protein] results in increased expression of SOD2 protein and Mercaptoethanol promotes the reaction [IL1A protein results in increased expression of SOD2 mRNA] CTD PMID:7476933 mercury dichloride increases expression EXP 6480464 Mercuric Chloride results in increased expression of IL1A protein CTD PMID:21984480 mesalamine multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased activity of NFE2L2 protein more ... CTD PMID:27818126 metam multiple interactions EXP 6480464 methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA] CTD PMID:15933225 metaproterenol decreases expression ISO IL1A (Homo sapiens) 6480464 Metaproterenol results in decreased expression of IL1A mRNA CTD PMID:32816093 methadone increases expression ISO Il1a (Rattus norvegicus) 6480464 Methadone results in increased expression of IL1A protein CTD PMID:20178837 methamphetamine multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Methamphetamine co-treated with SCH 23390] results in increased expression of IL1A mRNA and GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1A mRNA] CTD PMID:19564919 and PMID:36914120 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of IL1A mRNA CTD PMID:36914120 methamphetamine increases expression ISO Il1a (Rattus norvegicus) 6480464 Methamphetamine results in increased expression of IL1A mRNA CTD PMID:19564919 and PMID:36914120 methapyrilene increases expression ISO Il1a (Rattus norvegicus) 6480464 Methapyrilene results in increased expression of IL1A protein CTD PMID:25051504 methotrexate decreases expression ISO IL1A (Homo sapiens) 6480464 Methotrexate results in decreased expression of IL1A mRNA CTD PMID:17400583 methotrexate multiple interactions EXP 6480464 [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1A protein CTD PMID:31651976 methotrexate multiple interactions ISO IL1A (Homo sapiens) 6480464 [Folic Acid deficiency co-treated with Methotrexate] results in increased expression of IL1A mRNA CTD PMID:24657277 methotrexate increases expression ISO IL1A (Homo sapiens) 6480464 Methotrexate results in increased expression of IL1A mRNA CTD PMID:17379860 more ... methoxyacetic acid increases expression ISO Il1a (Rattus norvegicus) 6480464 methoxyacetic acid results in increased expression of IL1A mRNA CTD PMID:28238932 methyl methacrylate increases expression EXP 6480464 Methylmethacrylate results in increased expression of IL1A protein CTD PMID:23178550 methyl salicylate increases expression EXP 6480464 methyl salicylate results in increased expression of IL1A protein CTD PMID:23178550 methylisothiazolinone increases expression ISO IL1A (Homo sapiens) 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of IL1A mRNA CTD PMID:30806763 and PMID:31629900 metoprolol increases expression ISO IL1A (Homo sapiens) 6480464 Metoprolol results in increased expression of IL1A mRNA CTD PMID:17467819 metoprolol increases secretion ISO IL1A (Homo sapiens) 6480464 Metoprolol results in increased secretion of IL1A protein CTD PMID:17467819 mevalonic acid multiple interactions ISO IL1A (Homo sapiens) 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]] CTD PMID:15728660 mevalonic acid multiple interactions ISO Il1a (Rattus norvegicus) 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]] more ... CTD PMID:15705589 mexiletine multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to Mexiletine CTD PMID:19362101 Mezerein increases expression EXP 6480464 mezerein results in increased expression of IL1A mRNA and mezerein results in increased expression of IL1A protein CTD PMID:7665919 and PMID:8435107 Mezerein multiple interactions EXP 6480464 Plant Extracts inhibits the reaction [mezerein results in increased expression of IL1A mRNA] and Plant Extracts inhibits the reaction [mezerein results in increased expression of IL1A protein] CTD PMID:7665919 microcystin-LR increases expression EXP 6480464 cyanoginosin LR results in increased expression of IL1A mRNA CTD PMID:37342990 mifepristone multiple interactions ISO IL1A (Homo sapiens) 6480464 Mifepristone inhibits the reaction [Hydrocortisone inhibits the reaction [IL1A protein results in increased activity of MMP9 protein]] CTD PMID:18722610 mitomycin C increases expression ISO IL1A (Homo sapiens) 6480464 Mitomycin results in increased expression of IL1A mRNA CTD PMID:34624459 MJN110 multiple interactions EXP 6480464 ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL1A protein]] and MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL1A protein] CTD PMID:30301768 Mofezolac (TN) multiple interactions ISO IL1A (Homo sapiens) 6480464 mofezolac inhibits the reaction [IL1A protein results in increased abundance of Dinoprostone] CTD PMID:15167967 mono(2-ethylhexyl) phthalate increases expression ISO Il1a (Rattus norvegicus) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of IL1A mRNA CTD PMID:16809437 monocrotaline decreases expression ISO Il1a (Rattus norvegicus) 6480464 Monocrotaline results in decreased expression of IL1A protein CTD PMID:25051504 morphine multiple interactions EXP 6480464 Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein] more ... CTD PMID:12182845 morphine decreases expression EXP 6480464 Morphine results in decreased expression of IL1A protein CTD PMID:12182845 muramyl dipeptide increases response to substance EXP 6480464 IL1A protein results in increased susceptibility to Acetylmuramyl-Alanyl-Isoglutamine CTD PMID:19897531 N(gamma)-nitro-L-arginine methyl ester multiple interactions EXP 6480464 NG-Nitroarginine Methyl Ester inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of IL1A mRNA] CTD PMID:32142722 N,N-diethyl-m-toluamide multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL1A protein and [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IL1A mRNA CTD PMID:28659758 N,N-diethyl-m-toluamide multiple interactions EXP 6480464 [Pyridostigmine Bromide co-treated with DEET] results in increased secretion of IL1A protein CTD PMID:30339781 N-acetyl-L-cysteine multiple interactions ISO IL1A (Homo sapiens) 6480464 [Acetylcysteine co-treated with IL1A protein] results in increased expression of SOD2 protein more ... CTD PMID:24570342 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO IL1A (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein] and benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein] CTD PMID:11230753 and PMID:15728660 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of IL1A mRNA CTD PMID:20061341 N-ethylmaleimide multiple interactions ISO IL1A (Homo sapiens) 6480464 Ethylmaleimide inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA] and Ethylmaleimide inhibits the reaction [IL1A protein results in increased expression of SOD2 protein] CTD PMID:7476933 N-nitrosodiethylamine increases expression ISO Il1a (Rattus norvegicus) 6480464 Diethylnitrosamine results in increased expression of IL1A protein CTD PMID:25051504 N-nitrosodiethylamine multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with kojic acid] results in decreased expression of IL1A mRNA more ... CTD PMID:18544905 more ... N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of IL1A protein CTD PMID:18691550 N-nitrosodiethylamine multiple interactions EXP 6480464 Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]] more ... CTD PMID:18691550 N-nitrosodimethylamine multiple interactions EXP 6480464 CSF3 protein affects the reaction [Dimethylnitrosamine affects the expression of IL1A mRNA] CTD PMID:17869372 N-nitrosodimethylamine affects expression EXP 6480464 Dimethylnitrosamine affects the expression of IL1A mRNA CTD PMID:17869372 N-tosyl-L-phenylalanyl chloromethyl ketone multiple interactions ISO IL1A (Homo sapiens) 6480464 Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA] and Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1A protein results in increased expression of SOD2 protein] CTD PMID:7476933 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to Ranitidine CTD PMID:19362101 naloxone multiple interactions EXP 6480464 Naloxone inhibits the reaction [Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]] and Naloxone inhibits the reaction [Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]] CTD PMID:12182845 naproxen multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in decreased expression of IL1A protein] and Naproxen inhibits the reaction [Capsaicin results in decreased expression of IL1A protein] CTD PMID:22150557 nebivolol decreases expression ISO IL1A (Homo sapiens) 6480464 Nebivolol results in decreased expression of IL1A mRNA CTD PMID:17467819 nefazodone multiple interactions ISO IL1A (Homo sapiens) 6480464 [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to nefazodone CTD PMID:19362101 nefazodone decreases expression ISO IL1A (Homo sapiens) 6480464 nefazodone results in decreased expression of IL1A mRNA CTD PMID:32816093 nefazodone multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to nefazodone CTD PMID:19362101 neocuproine multiple interactions EXP 6480464 neocuproine inhibits the reaction [lipopolysaccharide and E coli O55-B5 results in increased expression of IL1A protein] CTD PMID:23604539 neoechinulin A decreases expression EXP 6480464 neoechinulin A results in decreased expression of IL1A mRNA CTD PMID:19818335 nickel atom increases expression ISO IL1A (Homo sapiens) 6480464 Nickel results in increased expression of IL1A mRNA CTD PMID:23195993 nickel dichloride increases expression ISO IL1A (Homo sapiens) 6480464 nickel chloride results in increased expression of IL1A mRNA CTD PMID:11378323 and PMID:17312168 nickel dichloride decreases expression EXP 6480464 nickel chloride results in decreased expression of IL1A protein CTD PMID:23178550 nickel dichloride multiple interactions ISO IL1A (Homo sapiens) 6480464 [nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of IL1A protein CTD PMID:18437699 nickel sulfate multiple interactions ISO IL1A (Homo sapiens) 6480464 IL1A protein affects the reaction [nickel sulfate results in increased secretion of CCL20 protein] and IL1A protein affects the reaction [nickel sulfate results in increased secretion of CXCL8 protein] CTD PMID:15679580 nickel sulfate increases secretion ISO IL1A (Homo sapiens) 6480464 nickel sulfate results in increased secretion of IL1A protein CTD PMID:15679580 nicotine multiple interactions ISO IL1A (Homo sapiens) 6480464 Nicotine results in increased expression of and results in increased secretion of IL1A protein CTD PMID:18082304 nimesulide multiple interactions ISO IL1A (Homo sapiens) 6480464 [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to nimesulide CTD PMID:19362101 nitric oxide multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide more ... CTD PMID:16968468 nitric oxide multiple interactions ISO Il1a (Rattus norvegicus) 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]] more ... CTD PMID:15705589 nitric oxide increases abundance ISO Il1a (Rattus norvegicus) 6480464 IL1A results in increased abundance of Nitric Oxide CTD PMID:15705589 nitrofen increases expression ISO Il1a (Rattus norvegicus) 6480464 nitrofen results in increased expression of IL1A mRNA CTD PMID:33484710 nitrososulfamethoxazole increases secretion ISO IL1A (Homo sapiens) 6480464 4-nitrososulfamethoxazole results in increased secretion of IL1A protein CTD PMID:28444390 nonane increases expression ISO Il1a (Rattus norvegicus) 6480464 nonane results in increased expression of IL1A protein CTD PMID:15451557 nonanoic acid increases expression EXP 6480464 pelargonic acid results in increased expression of IL1A mRNA CTD PMID:18652873 Nonidet P-40 decreases expression ISO IL1A (Homo sapiens) 6480464 Nonidet P-40 results in decreased expression of IL1A mRNA CTD PMID:26552463 Nonylphenol multiple interactions ISO IL1A (Homo sapiens) 6480464 fulvestrant inhibits the reaction [nonylphenol inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]] more ... CTD PMID:10614622 nortriptyline multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to Nortriptyline CTD PMID:19362101 notoginsenoside R1 multiple interactions EXP 6480464 notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL1A mRNA] CTD PMID:25472953 NS-398 multiple interactions ISO IL1A (Homo sapiens) 6480464 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]] more ... CTD PMID:11230753 and PMID:15167967 ochratoxin A increases expression ISO IL1A (Homo sapiens) 6480464 ochratoxin A results in increased expression of IL1A mRNA CTD PMID:28286205 octenidine increases expression ISO IL1A (Homo sapiens) 6480464 octenidine results in increased expression of IL1A mRNA CTD PMID:30240708 oleic acid multiple interactions ISO IL1A (Homo sapiens) 6480464 [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of IL1A mRNA and [Palmitic Acid co-treated with Oleic Acid] affects the expression of IL1A mRNA CTD PMID:30547786 orciprenaline decreases expression ISO IL1A (Homo sapiens) 6480464 Metaproterenol results in decreased expression of IL1A mRNA CTD PMID:32816093 Osajin decreases expression ISO IL1A (Homo sapiens) 6480464 osajin results in decreased expression of IL1A mRNA CTD PMID:20706672 oxaliplatin multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of IL1A mRNA CTD PMID:25729387 ozone increases expression EXP 6480464 Ozone results in increased expression of IL1A mRNA CTD PMID:17575079 ozone decreases expression EXP 6480464 Ozone results in decreased expression of IL1A protein CTD PMID:28533327 ozone multiple interactions ISO IL1A (Homo sapiens) 6480464 [[Air Pollutants results in increased abundance of Ozone] which co-treated with IL1A protein] results in decreased phosphorylation of MTOR mRNA more ... CTD PMID:21043989 more ... ozone increases expression ISO IL1A (Homo sapiens) 6480464 Ozone results in increased expression of IL1A mRNA CTD PMID:31476115 ozone multiple interactions EXP 6480464 [LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of IL1A protein CTD PMID:27472835 ozone multiple interactions ISO Il1a (Rattus norvegicus) 6480464 TNF protein promotes the reaction [Ozone results in increased expression of IL1A mRNA] CTD PMID:12377989 ozone increases expression ISO Il1a (Rattus norvegicus) 6480464 Ozone results in increased expression of IL1A mRNA CTD PMID:12377989 and PMID:28623178 paliperidone palmitate increases expression ISO IL1A (Homo sapiens) 6480464 Paliperidone Palmitate results in increased expression of IL1A mRNA CTD PMID:32816093 paracetamol multiple interactions EXP 6480464 IFNG protein promotes the reaction [Acetaminophen results in increased expression of IL1A mRNA] more ... CTD PMID:11826401 more ... paracetamol increases expression ISO Il1a (Rattus norvegicus) 6480464 Acetaminophen results in increased expression of IL1A mRNA CTD PMID:33387578 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of IL1A mRNA CTD PMID:11826401 more ... paracetamol multiple interactions ISO Il1a (Rattus norvegicus) 6480464 Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of IL1A mRNA] and Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of IL1A protein] CTD PMID:19265712 paraquat increases expression ISO IL1A (Homo sapiens) 6480464 Paraquat results in increased expression of IL1A mRNA CTD PMID:20883675 more ... paraquat multiple interactions EXP 6480464 [Resveratrol co-treated with Tetracyclines] inhibits the reaction [Paraquat results in increased expression of IL1A protein] CTD PMID:28090784 paraquat multiple interactions ISO IL1A (Homo sapiens) 6480464 IL1A protein promotes the reaction [Paraquat results in increased expression of CAT protein] more ... CTD PMID:8317554 paraquat increases expression EXP 6480464 Paraquat results in increased expression of IL1A mRNA and Paraquat results in increased expression of IL1A protein CTD PMID:22938100 more ... paricalcitol multiple interactions EXP 6480464 [Phosphorus co-treated with paricalcitol] results in increased expression of IL1A mRNA CTD PMID:17715259 parthenolide decreases expression ISO IL1A (Homo sapiens) 6480464 parthenolide results in decreased expression of IL1A mRNA CTD PMID:16921510 pemetrexed multiple interactions ISO IL1A (Homo sapiens) 6480464 [Folic Acid affects the susceptibility to Pemetrexed] which affects the expression of IL1A mRNA CTD PMID:22975265 penbutolol increases expression ISO IL1A (Homo sapiens) 6480464 Penbutolol results in increased expression of IL1A mRNA CTD PMID:32816093 pentane-2,3-dione increases expression ISO Il1a (Rattus norvegicus) 6480464 2 and 3-pentanedione results in increased expression of IL1A mRNA CTD PMID:25710175 peptidoglycan increases expression ISO IL1A (Homo sapiens) 6480464 Peptidoglycan results in increased expression of IL1A mRNA CTD PMID:15860229 perfluorododecanoic acid decreases expression ISO Il1a (Rattus norvegicus) 6480464 perfluorododecanoic acid results in decreased expression of IL1A mRNA CTD PMID:19397962 perfluorooctane-1-sulfonic acid decreases expression ISO IL1A (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of IL1A mRNA CTD PMID:32790152 perfluorooctanoic acid decreases expression ISO IL1A (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of IL1A mRNA CTD PMID:32790152 permethrin multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL1A protein and [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IL1A mRNA CTD PMID:28659758 permethrin decreases expression ISO IL1A (Homo sapiens) 6480464 Permethrin results in decreased expression of IL1A mRNA CTD PMID:37047231 phenethyl caffeate multiple interactions ISO IL1A (Homo sapiens) 6480464 caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL1A mRNA] CTD PMID:16085347 phenethyl isothiocyanate multiple interactions EXP 6480464 phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA] CTD PMID:20423518 phenobarbital increases expression ISO Il1a (Rattus norvegicus) 6480464 Phenobarbital results in increased expression of IL1A protein CTD PMID:25051504 phenobarbital decreases expression ISO Il1a (Rattus norvegicus) 6480464 Phenobarbital results in decreased expression of IL1A mRNA CTD PMID:19162173 phenol increases secretion ISO IL1A (Homo sapiens) 6480464 Phenol results in increased secretion of IL1A protein CTD PMID:16522979 phenol multiple interactions ISO IL1A (Homo sapiens) 6480464 IL1A protein affects the reaction [Phenol results in increased expression of CXCL8 protein] CTD PMID:8006454 phenol increases expression ISO IL1A (Homo sapiens) 6480464 Phenol results in increased expression of IL1A mRNA and Phenol results in increased expression of IL1A protein CTD PMID:8006454 phloretin multiple interactions ISO IL1A (Homo sapiens) 6480464 Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein] CTD PMID:24707119 phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 5 more ... CTD PMID:11851881 more ... phorbol 13-acetate 12-myristate increases expression ISO IL1A (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA CTD PMID:21045076 and PMID:8702551 phorbol 13-acetate 12-myristate increases expression EXP 6480464 Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA and Tetradecanoylphorbol Acetate results in increased expression of IL1A protein CTD PMID:11851881 more ... phorbol 13-acetate 12-myristate multiple interactions ISO IL1A (Homo sapiens) 6480464 [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1A mRNA more ... CTD PMID:21045076 more ... phosphorus atom multiple interactions EXP 6480464 [Phosphorus co-treated with paricalcitol] results in increased expression of IL1A mRNA CTD PMID:17715259 phosphorus(.) multiple interactions EXP 6480464 [Phosphorus co-treated with paricalcitol] results in increased expression of IL1A mRNA CTD PMID:17715259 phthalic anhydride increases activity EXP 6480464 phthalic anhydride results in increased activity of IL1A protein CTD PMID:15840424 pimecrolimus increases secretion EXP 6480464 pimecrolimus results in increased secretion of IL1A protein CTD PMID:15086553 pioglitazone increases expression ISO IL1A (Homo sapiens) 6480464 Pioglitazone results in increased expression of IL1A mRNA CTD PMID:32816093 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of IL1A protein CTD PMID:20131406 polycyclic arene increases expression ISO IL1A (Homo sapiens) 152975620 polycyclic arene increases expression of IL1A mRNA in lung epithelial cell RGD polymyxin B2 multiple interactions ISO IL1A (Homo sapiens) 6480464 Polymyxin B inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA] CTD PMID:21703343 potassium chromate multiple interactions ISO IL1A (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of IL1A mRNA CTD PMID:22079256 potassium chromate decreases expression ISO IL1A (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of IL1A mRNA CTD PMID:22079256 potassium dichromate increases secretion ISO IL1A (Homo sapiens) 6480464 Potassium Dichromate results in increased secretion of IL1A protein CTD PMID:20619327 potassium dichromate increases expression ISO IL1A (Homo sapiens) 6480464 Potassium Dichromate results in increased expression of IL1A mRNA CTD PMID:20619327 potassium hydroxide multiple interactions ISO IL1A (Homo sapiens) 6480464 potassium hydroxide results in increased expression of and results in increased secretion of IL1A protein CTD PMID:21469165 pregnenolone 16alpha-carbonitrile decreases expression ISO Il1a (Rattus norvegicus) 6480464 Pregnenolone Carbonitrile results in decreased expression of IL1A mRNA CTD PMID:19162173 primaquine decreases expression ISO IL1A (Homo sapiens) 6480464 Primaquine results in decreased expression of IL1A mRNA CTD PMID:32816093 primidone increases expression ISO IL1A (Homo sapiens) 6480464 Primidone results in increased expression of IL1A mRNA CTD PMID:32816093 probenecid multiple interactions EXP 6480464 1 more ... CTD PMID:25406165 procyclidine increases expression ISO IL1A (Homo sapiens) 6480464 Procyclidine results in increased expression of IL1A mRNA CTD PMID:32816093 promethazine increases expression ISO IL1A (Homo sapiens) 6480464 Promethazine results in increased expression of IL1A mRNA CTD PMID:32816093 propamocarb multiple interactions EXP 6480464 propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL1A mRNA] and propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL1A protein] CTD PMID:34426332 propan-2-ol decreases expression EXP 6480464 2-Propanol results in decreased expression of IL1A protein CTD PMID:23178550 prostaglandin E2 increases abundance EXP 6480464 IL1A protein results in increased abundance of Dinoprostone CTD PMID:8218930 prostaglandin E2 multiple interactions ISO IL1A (Homo sapiens) 6480464 mofezolac inhibits the reaction [IL1A protein results in increased abundance of Dinoprostone] and N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [IL1A protein results in increased abundance of Dinoprostone] CTD PMID:15167967 prostaglandin E2 multiple interactions EXP 6480464 [IL1A protein co-treated with Arachidonic Acid] results in increased abundance of Dinoprostone CTD PMID:11351503 prostaglandin E2 increases abundance ISO IL1A (Homo sapiens) 6480464 IL1A protein results in increased abundance of Dinoprostone CTD PMID:15167967 and PMID:21513769 prostaglandin E2 increases secretion ISO Il1a (Rattus norvegicus) 6480464 IL1A protein results in increased secretion of Dinoprostone CTD PMID:16169897 prostaglandin F2alpha increases abundance ISO IL1A (Homo sapiens) 6480464 IL1A protein results in increased abundance of Dinoprost CTD PMID:21513769 prostaglandin I2 increases abundance ISO IL1A (Homo sapiens) 6480464 IL1A protein results in increased abundance of Epoprostenol CTD PMID:21513769 pterostilbene multiple interactions EXP 6480464 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1A mRNA]] and pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1A mRNA] CTD PMID:34405320 pterostilbene multiple interactions ISO IL1A (Homo sapiens) 6480464 NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of IL1A protein]] and pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of IL1A protein] CTD PMID:34474091 puerarin decreases expression ISO IL1A (Homo sapiens) 6480464 puerarin results in decreased expression of IL1A mRNA CTD PMID:20706672 Pyridostigmine bromide multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL1A protein and [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IL1A mRNA CTD PMID:28659758 Pyridostigmine bromide multiple interactions EXP 6480464 [Pyridostigmine Bromide co-treated with DEET] results in increased secretion of IL1A protein CTD PMID:30339781 quartz increases import EXP 6480464 Quartz results in increased import of IL1A protein CTD PMID:36840754 quartz increases expression EXP 6480464 Quartz results in increased expression of IL1A mRNA CTD PMID:36840754 quartz multiple interactions EXP 6480464 Cytochalasin D inhibits the reaction [Quartz results in increased import of IL1A protein] more ... CTD PMID:36840754 quercetin decreases expression ISO IL1A (Homo sapiens) 6480464 Quercetin results in decreased expression of IL1A mRNA CTD PMID:23727915 quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of IL1A mRNA CTD PMID:22185406 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA] CTD PMID:22185406 quercetin multiple interactions ISO IL1A (Homo sapiens) 6480464 Quercetin inhibits the reaction [IL1A protein results in increased expression of PRKCQ protein modified form] more ... CTD PMID:16532021 and PMID:17929310 quercetin 3-O-beta-D-glucofuranoside multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [isoquercitrin analog co-treated with Propylthiouracil] results in increased expression of IL1A mRNA and [isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA CTD PMID:21295105 and PMID:31068541 quercetin 3-O-beta-D-glucopyranoside multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [isoquercitrin analog co-treated with Propylthiouracil] results in increased expression of IL1A mRNA and [isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA CTD PMID:21295105 and PMID:31068541 quinacrine multiple interactions EXP 6480464 Quinacrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA] CTD PMID:8435107 quinine multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to Quinine CTD PMID:19362101 rac-lactic acid increases expression EXP 6480464 Lactic Acid results in increased expression of IL1A protein CTD PMID:23178550 rac-lactic acid affects expression ISO IL1A (Homo sapiens) 6480464 Lactic Acid affects the expression of IL1A mRNA CTD PMID:30851411 rac-lactic acid increases secretion ISO IL1A (Homo sapiens) 6480464 Lactic Acid results in increased secretion of IL1A protein CTD PMID:23999410 ranitidine multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to Ranitidine CTD PMID:19362101 resorcinol increases expression ISO IL1A (Homo sapiens) 6480464 resorcinol results in increased expression of IL1A mRNA CTD PMID:30806763 resveratrol decreases expression ISO IL1A (Homo sapiens) 6480464 resveratrol results in decreased expression of IL1A mRNA CTD PMID:20706672 and PMID:22933405 resveratrol multiple interactions EXP 6480464 [Resveratrol co-treated with Tetracyclines] inhibits the reaction [Paraquat results in increased expression of IL1A protein] CTD PMID:28090784 resveratrol decreases expression EXP 6480464 resveratrol analog results in decreased expression of IL1A mRNA CTD PMID:15652768 resveratrol multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with resveratrol] results in increased activity of NFE2L2 protein more ... CTD PMID:17929310 more ... Riluzole multiple interactions ISO IL1A (Homo sapiens) 6480464 [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to Riluzole CTD PMID:19362101 rofecoxib affects expression ISO IL1A (Homo sapiens) 6480464 rofecoxib affects the expression of IL1A mRNA CTD PMID:17070997 rofecoxib decreases expression ISO IL1A (Homo sapiens) 6480464 rofecoxib results in decreased expression of IL1A mRNA CTD PMID:32816093 Roridin A increases expression EXP 6480464 roridin A results in increased expression of IL1A mRNA CTD PMID:17483119 Roridin A multiple interactions EXP 6480464 [lipopolysaccharide and Escherichia coli O111 B4 co-treated with roridin A] affects the expression of IL1A mRNA CTD PMID:17483119 rotenone multiple interactions EXP 6480464 Rotenone inhibits the reaction [sodium arsenate results in increased expression of IL1A protein] and Rotenone inhibits the reaction [tributyltin results in increased expression of IL1A protein] CTD PMID:10571731 and PMID:8875956 rotenone increases expression ISO IL1A (Homo sapiens) 6480464 Rotenone results in increased expression of IL1A mRNA CTD PMID:32949572 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO IL1A (Homo sapiens) 6480464 [S-(1 more ... CTD PMID:35811015 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP 6480464 [zomepirac co-treated with Buthionine Sulfoximine co-treated with tri-o-cresyl phosphate] results in increased expression of IL1A mRNA and LY6G protein affects the reaction [[zomepirac co-treated with Buthionine Sulfoximine co-treated with tri-o-cresyl phosphate] results in increased expression of IL1A mRNA] CTD PMID:29154782 salicylic acid increases expression EXP 6480464 Salicylic Acid results in increased expression of IL1A protein CTD PMID:23178550 SB 203580 multiple interactions ISO IL1A (Homo sapiens) 6480464 SB 203580 inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein] more ... CTD PMID:14742690 more ... SB-202190 multiple interactions ISO IL1A (Homo sapiens) 152975620 SB-202190 inhibits the reaction [benzo[a]pyrene and polycyclic arene increases expression of IL1A mRNA in lung epithelial cell] RGD SCH 23390 multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Methamphetamine co-treated with SCH 23390] results in increased expression of IL1A mRNA CTD PMID:19564919 SCH 23390 increases expression ISO Il1a (Rattus norvegicus) 6480464 SCH 23390 results in increased expression of IL1A mRNA CTD PMID:19564919 scopolamine decreases response to substance EXP 6480464 IL1A protein results in decreased susceptibility to Scopolamine CTD PMID:8003924 serpentine asbestos increases expression EXP 6480464 Asbestos and Serpentine results in increased expression of IL1A protein CTD PMID:17200189 serpentine asbestos multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Asbestos and Serpentine co-treated with Lipopolysaccharides] results in increased expression of IL1A mRNA CTD PMID:9400719 serpentine asbestos increases expression ISO IL1A (Homo sapiens) 6480464 Asbestos and Serpentine results in increased expression of IL1A mRNA CTD PMID:24160326 silibinin multiple interactions ISO IL1A (Homo sapiens) 6480464 Silybin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein] CTD PMID:33839235 silicon dioxide multiple interactions EXP 6480464 [Chromium Alloys co-treated with titanium alloy (TiAl6V4) co-treated with titanium nitride co-treated with Silicon Dioxide] results in increased expression of IL1A protein more ... CTD PMID:12168658 and PMID:22155353 silicon dioxide multiple interactions ISO IL1A (Homo sapiens) 6480464 CXCL16 mRNA promotes the reaction [Silicon Dioxide results in increased expression of and results in increased secretion of IL1A protein] more ... CTD PMID:32316988 and PMID:34653535 silicon dioxide increases secretion ISO IL1A (Homo sapiens) 6480464 Silicon Dioxide results in increased secretion of IL1A protein CTD PMID:32316988 silicon dioxide increases secretion EXP 6480464 Silicon Dioxide results in increased secretion of IL1A protein CTD PMID:29484482 silicon dioxide increases expression ISO IL1A (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of IL1A mRNA and Silicon Dioxide results in increased expression of IL1A mRNA CTD PMID:19428942 more ... silver atom affects expression ISO IL1A (Homo sapiens) 6480464 Silver affects the expression of IL1A mRNA CTD PMID:22342292 silver atom multiple interactions ISO IL1A (Homo sapiens) 6480464 Silver promotes the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA] CTD PMID:26968431 silver atom increases expression ISO IL1A (Homo sapiens) 6480464 Silver results in increased expression of IL1A mRNA CTD PMID:26968431 silver(0) affects expression ISO IL1A (Homo sapiens) 6480464 Silver affects the expression of IL1A mRNA CTD PMID:22342292 silver(0) multiple interactions ISO IL1A (Homo sapiens) 6480464 Silver promotes the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA] CTD PMID:26968431 silver(0) increases expression ISO IL1A (Homo sapiens) 6480464 Silver results in increased expression of IL1A mRNA CTD PMID:26968431 simvastatin multiple interactions ISO IL1A (Homo sapiens) 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]] more ... CTD PMID:15728660 simvastatin multiple interactions ISO Il1a (Rattus norvegicus) 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]] more ... CTD PMID:15705589 sodium arsenate multiple interactions EXP 6480464 Ethidium inhibits the reaction [sodium arsenate results in increased expression of IL1A protein] and Rotenone inhibits the reaction [sodium arsenate results in increased expression of IL1A protein] CTD PMID:10571731 sodium arsenate increases expression EXP 6480464 sodium arsenate results in increased expression of IL1A protein CTD PMID:10571731 sodium arsenite multiple interactions ISO IL1A (Homo sapiens) 6480464 2 more ... CTD PMID:24570342 sodium arsenite multiple interactions EXP 6480464 [sodium arsenite co-treated with 9 more ... CTD PMID:35364107 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of IL1A mRNA and sodium arsenite results in increased expression of IL1A protein CTD PMID:35364107 and PMID:37682722 sodium arsenite multiple interactions ISO Il1a (Rattus norvegicus) 6480464 4 more ... CTD PMID:35993674 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of IL1A mRNA CTD PMID:21911445 sodium arsenite increases expression ISO IL1A (Homo sapiens) 6480464 sodium arsenite results in increased expression of IL1A mRNA CTD PMID:20886546 more ... sodium arsenite decreases expression ISO IL1A (Homo sapiens) 6480464 sodium arsenite results in decreased expression of IL1A mRNA CTD PMID:12679051 sodium chloride increases expression ISO IL1A (Homo sapiens) 6480464 Sodium Chloride results in increased expression of IL1A mRNA CTD PMID:11378323 sodium dichromate increases expression ISO Il1a (Rattus norvegicus) 6480464 sodium bichromate results in increased expression of IL1A protein CTD PMID:22011396 sodium dodecyl sulfate multiple interactions ISO IL1A (Homo sapiens) 6480464 IL1A protein affects the reaction [Sodium Dodecyl Sulfate results in increased secretion of CCL20 protein] more ... CTD PMID:15679580 and PMID:21469165 sodium dodecyl sulfate decreases expression ISO IL1A (Homo sapiens) 6480464 Sodium Dodecyl Sulfate results in decreased expression of IL1A protein CTD PMID:19878710 sodium dodecyl sulfate increases expression ISO IL1A (Homo sapiens) 6480464 Sodium Dodecyl Sulfate results in increased expression of IL1A mRNA and Sodium Dodecyl Sulfate results in increased expression of IL1A protein CTD PMID:11378323 more ... sodium dodecyl sulfate increases secretion ISO IL1A (Homo sapiens) 6480464 Sodium Dodecyl Sulfate results in increased secretion of IL1A protein CTD PMID:12781210 and PMID:15679580 sodium fluoride increases expression ISO Il1a (Rattus norvegicus) 6480464 Sodium Fluoride results in increased expression of IL1A protein CTD PMID:37121298 sodium perchlorate increases expression ISO Il1a (Rattus norvegicus) 6480464 sodium perchlorate results in increased expression of IL1A mRNA CTD PMID:29139221 streptozocin multiple interactions EXP 6480464 [Streptozocin co-treated with bisphenol A] results in increased expression of IL1A mRNA more ... CTD PMID:24781736 sulindac multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Sulindac co-treated with lipopolysaccharide and E coli O55-B5] affects the expression of IL1A mRNA CTD PMID:20371263 sumatriptan multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in decreased expression of IL1A protein] and Sumatriptan inhibits the reaction [Capsaicin results in decreased expression of IL1A protein] CTD PMID:22150557 T-2 toxin decreases methylation ISO Il1a (Rattus norvegicus) 6480464 T-2 Toxin results in decreased methylation of IL1A promoter CTD PMID:31279042 T-2 toxin increases expression ISO Il1a (Rattus norvegicus) 6480464 T-2 Toxin results in increased expression of IL1A mRNA CTD PMID:31279042 T-2 toxin increases expression EXP 6480464 T-2 Toxin results in increased expression of IL1A mRNA CTD PMID:21112371 and PMID:36775139 telithromycin multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to telithromycin CTD PMID:19362101 terameprocol multiple interactions EXP 6480464 terameprocol affects the reaction [Lipopolysaccharides results in increased expression of IL1A protein] CTD PMID:19133137 testosterone affects expression EXP 6480464 Testosterone affects the expression of IL1A protein CTD PMID:20403060 testosterone multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of IL1A mRNA CTD PMID:32741896 testosterone enanthate increases expression ISO Il1a (Rattus norvegicus) 6480464 testosterone enanthate results in increased expression of IL1A protein CTD PMID:30154949 testosterone enanthate multiple interactions ISO Il1a (Rattus norvegicus) 6480464 2-Methoxyestradiol inhibits the reaction [testosterone enanthate results in increased expression of IL1A protein] CTD PMID:30154949 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of IL1A mRNA and Carbon Tetrachloride results in increased expression of IL1A protein CTD PMID:18395288 more ... tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of IL1A mRNA CTD PMID:31919559 tetrachloromethane increases activity ISO Il1a (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased activity of IL1A protein CTD PMID:25858767 tetrachloromethane increases expression ISO Il1a (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of IL1A protein CTD PMID:17904177 tetrachloromethane multiple interactions EXP 6480464 CD44 protein affects the reaction [Carbon Tetrachloride results in increased expression of IL1A mRNA] more ... CTD PMID:18395288 more ... tetracyclines multiple interactions EXP 6480464 [Resveratrol co-treated with Tetracyclines] inhibits the reaction [Paraquat results in increased expression of IL1A protein] CTD PMID:28090784 tetradecane multiple interactions ISO IL1A (Homo sapiens) 6480464 n-tetradecane results in increased expression of and results in increased secretion of IL1A protein CTD PMID:19720135 Tetramethylthiourea multiple interactions ISO Il1a (Rattus norvegicus) 6480464 tetramethylthiourea inhibits the reaction [Asbestos and Crocidolite results in increased expression of IL1A mRNA] CTD PMID:7539275 tetraphene increases expression ISO IL1A (Homo sapiens) 6480464 benz(a)anthracene results in increased expression of IL1A mRNA CTD PMID:8156173 tetrathiomolybdate(2-) multiple interactions EXP 6480464 tetrathiomolybdate inhibits the reaction [lipopolysaccharide and E coli O55-B5 results in increased secretion of IL1A protein] CTD PMID:21724870 thioacetamide increases expression ISO Il1a (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of IL1A mRNA and Thioacetamide results in increased expression of IL1A protein CTD PMID:25051504 and PMID:34492290 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of IL1A mRNA CTD PMID:36343683 thioacetamide multiple interactions EXP 6480464 Edaravone inhibits the reaction [Thioacetamide results in increased expression of IL1A mRNA] CTD PMID:36343683 thiostrepton decreases expression ISO IL1A (Homo sapiens) 6480464 Thiostrepton results in decreased expression of IL1A mRNA CTD PMID:22321511 thiram increases expression ISO IL1A (Homo sapiens) 6480464 Thiram results in increased expression of IL1A mRNA CTD PMID:33715048 tienilic acid increases expression ISO IL1A (Homo sapiens) 6480464 Ticrynafen results in increased expression of IL1A mRNA CTD PMID:32816093 titanium dioxide affects expression ISO IL1A (Homo sapiens) 6480464 titanium dioxide affects the expression of IL1A mRNA CTD PMID:19695317 and PMID:22342292 TMC-120A decreases expression EXP 6480464 TMC 120A results in decreased expression of IL1A mRNA CTD PMID:19818335 Tolmetin glucuronide increases expression ISO IL1A (Homo sapiens) 6480464 tolmetin glucuronide results in increased expression of IL1A mRNA CTD PMID:26528891 toluene 2,4-diisocyanate multiple interactions EXP 6480464 IL1A protein affects the reaction [Toluene 2 more ... CTD PMID:16210060 toluene 2,4-diisocyanate increases secretion ISO IL1A (Homo sapiens) 6480464 Toluene 2 and 4-Diisocyanate results in increased secretion of IL1A protein CTD PMID:1699434 topotecan multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of IL1A mRNA CTD PMID:25729387 topotecan increases expression ISO Il1a (Rattus norvegicus) 6480464 Topotecan results in increased expression of IL1A mRNA CTD PMID:25729387 toremifene multiple interactions EXP 6480464 Toremifene inhibits the reaction [Estradiol results in increased expression of IL1A mRNA] and Toremifene inhibits the reaction [Estradiol results in increased expression of IL1A protein] CTD PMID:12079510 trans-isoeugenol increases expression EXP 6480464 isoeugenol results in increased expression of IL1A protein CTD PMID:23178550 trazodone increases expression ISO IL1A (Homo sapiens) 6480464 Trazodone results in increased expression of IL1A mRNA CTD PMID:32816093 tremolite asbestos increases expression EXP 6480464 tremolite results in increased expression of IL1A mRNA CTD PMID:29279043 tributylstannane multiple interactions EXP 6480464 1 more ... CTD PMID:8875956 and PMID:9221826 tributylstannane increases expression EXP 6480464 tributyltin results in increased expression of IL1A protein CTD PMID:8875956 and PMID:9221826 trichloroethene increases methylation ISO Il1a (Rattus norvegicus) 6480464 Trichloroethylene results in increased methylation of IL1A gene CTD PMID:27618143 trichloroethene decreases expression ISO Il1a (Rattus norvegicus) 6480464 Trichloroethylene results in decreased expression of IL1A mRNA CTD PMID:33387578 trichostatin A decreases expression ISO IL1A (Homo sapiens) 6480464 trichostatin A results in decreased expression of IL1A mRNA CTD PMID:24935251 trichostatin A increases expression ISO IL1A (Homo sapiens) 6480464 trichostatin A results in increased expression of IL1A mRNA CTD PMID:24935251 triclosan decreases expression EXP 6480464 Triclosan results in decreased expression of IL1A protein CTD PMID:26048654 tridecane multiple interactions ISO IL1A (Homo sapiens) 6480464 tridecane results in increased expression of and results in increased secretion of IL1A protein CTD PMID:19720135 Trihexyphenidyl increases expression ISO IL1A (Homo sapiens) 6480464 Trihexyphenidyl results in increased expression of IL1A mRNA CTD PMID:32816093 trimethyltin increases expression EXP 6480464 trimethyltin results in increased expression of IL1A mRNA CTD PMID:20833246 more ... triptonide increases expression EXP 6480464 triptonide results in increased expression of IL1A mRNA CTD PMID:33045310 Triton X-100 increases secretion ISO IL1A (Homo sapiens) 6480464 Octoxynol results in increased secretion of IL1A protein CTD PMID:23999410 troglitazone decreases expression ISO IL1A (Homo sapiens) 6480464 troglitazone results in decreased expression of IL1A mRNA CTD PMID:19631733 troglitazone increases expression ISO IL1A (Homo sapiens) 6480464 Troglitazone results in increased expression of IL1A mRNA CTD PMID:32816093 trovafloxacin multiple interactions ISO IL1A (Homo sapiens) 6480464 [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide more ... CTD PMID:19362101 trovafloxacin increases expression EXP 6480464 trovafloxacin results in increased expression of IL1A mRNA CTD PMID:35537566 trovafloxacin multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin CTD PMID:19362101 urethane multiple interactions ISO IL1A (Homo sapiens) 6480464 Urethane results in increased expression of and results in increased secretion of IL1A protein CTD PMID:18082304 usnic acid multiple interactions ISO IL1A (Homo sapiens) 6480464 [usnic acid co-treated with Lipopolysaccharides] results in decreased expression of IL1A mRNA CTD PMID:22777745 vadimezan increases expression ISO Il1a (Rattus norvegicus) 6480464 vadimezan results in increased expression of IL1A protein CTD PMID:16944150 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of IL1A mRNA CTD PMID:17292431 valproic acid decreases expression ISO IL1A (Homo sapiens) 6480464 Valproic Acid results in decreased expression of IL1A mRNA CTD PMID:32816093 valproic acid increases expression ISO IL1A (Homo sapiens) 6480464 Valproic Acid results in increased expression of IL1A mRNA CTD PMID:28001369 valproic acid affects expression ISO IL1A (Homo sapiens) 6480464 Valproic Acid affects the expression of IL1A mRNA CTD PMID:25979313 vanadium atom increases expression ISO Il1a (Rattus norvegicus) 6480464 Vanadium results in increased expression of IL1A mRNA CTD PMID:15159208 vanadium(0) increases expression ISO Il1a (Rattus norvegicus) 6480464 Vanadium results in increased expression of IL1A mRNA CTD PMID:15159208 vanadyl sulfate increases expression ISO IL1A (Homo sapiens) 6480464 vanadyl sulfate results in increased expression of IL1A mRNA CTD PMID:16330358 verapamil multiple interactions ISO IL1A (Homo sapiens) 6480464 Verapamil inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA] CTD PMID:15613243 vinclozolin increases expression ISO Il1a (Rattus norvegicus) 6480464 vinclozolin results in increased expression of IL1A mRNA CTD PMID:18629315 vorinostat increases expression ISO IL1A (Homo sapiens) 6480464 vorinostat results in increased expression of IL1A mRNA CTD PMID:18769122 vorinostat multiple interactions ISO IL1A (Homo sapiens) 6480464 ELF3 protein inhibits the reaction [Vorinostat inhibits the reaction [IL1A protein results in decreased expression of COL2A1 mRNA]] more ... CTD PMID:34250664 wortmannin multiple interactions ISO IL1A (Homo sapiens) 6480464 wortmannin inhibits the reaction [Ciprofloxacin inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]] CTD PMID:16968468 Y-27632 multiple interactions ISO Il1a (Rattus norvegicus) 6480464 Y 27632 inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]] and Y 27632 inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]] CTD PMID:15705589 Z-Val-Phe-H affects localization ISO IL1A (Homo sapiens) 6480464 calpain inhibitor III affects the localization of IL1A protein CTD PMID:24024155 zidovudine increases expression ISO IL1A (Homo sapiens) 6480464 Zidovudine results in increased expression of IL1A protein CTD PMID:7979221 zinc atom increases expression ISO Il1a (Rattus norvegicus) 6480464 Zinc results in increased expression of IL1A mRNA CTD PMID:15159208 zinc atom multiple interactions ISO IL1A (Homo sapiens) 6480464 Zinc promotes the reaction [IL1A protein results in increased expression of MT2A mRNA] CTD PMID:1502195 zinc atom increases uptake ISO IL1A (Homo sapiens) 6480464 IL1A protein results in increased uptake of Zinc CTD PMID:1502195 zinc atom affects metabolic processing ISO IL1A (Homo sapiens) 6480464 IL1A protein affects the metabolism of Zinc CTD PMID:2458983 zinc atom multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [IL1A protein co-treated with Zinc deficiency] results in increased expression of NOS2 protein more ... CTD PMID:12514266 more ... zinc atom increases abundance ISO IL1A (Homo sapiens) 6480464 IL1A protein results in increased abundance of Zinc CTD PMID:9278552 zinc dichloride increases expression EXP 6480464 zinc chloride results in increased expression of IL1A protein CTD PMID:18509044 zinc dichloride multiple interactions EXP 6480464 N-(oxo-5 more ... CTD PMID:18509044 zinc oxide affects expression ISO Il1a (Rattus norvegicus) 6480464 Zinc Oxide affects the expression of IL1A protein CTD PMID:33205376 zinc sulfate multiple interactions ISO IL1A (Homo sapiens) 6480464 IL1A protein promotes the reaction [Zinc Sulfate results in increased expression of MT1G mRNA] more ... CTD PMID:22722935 zinc sulfate decreases expression ISO IL1A (Homo sapiens) 6480464 Zinc Sulfate results in decreased expression of IL1A mRNA CTD PMID:22722935 zinc(0) increases expression ISO Il1a (Rattus norvegicus) 6480464 Zinc results in increased expression of IL1A mRNA CTD PMID:15159208 zinc(0) increases abundance ISO IL1A (Homo sapiens) 6480464 IL1A protein results in increased abundance of Zinc CTD PMID:9278552 zinc(0) multiple interactions ISO Il1a (Rattus norvegicus) 6480464 [IL1A protein co-treated with Zinc deficiency] results in increased expression of NOS2 protein more ... CTD PMID:12514266 more ... zinc(0) affects metabolic processing ISO IL1A (Homo sapiens) 6480464 IL1A protein affects the metabolism of Zinc CTD PMID:2458983 zinc(0) increases uptake ISO IL1A (Homo sapiens) 6480464 IL1A protein results in increased uptake of Zinc CTD PMID:1502195 zinc(0) multiple interactions ISO IL1A (Homo sapiens) 6480464 Zinc promotes the reaction [IL1A protein results in increased expression of MT2A mRNA] CTD PMID:1502195 zomepirac multiple interactions EXP 6480464 [zomepirac co-treated with Buthionine Sulfoximine co-treated with tri-o-cresyl phosphate] results in increased expression of IL1A mRNA and LY6G protein affects the reaction [[zomepirac co-treated with Buthionine Sulfoximine co-treated with tri-o-cresyl phosphate] results in increased expression of IL1A mRNA] CTD PMID:29154782 zomepirac increases expression ISO IL1A (Homo sapiens) 6480464 zomepirac metabolite results in increased expression of IL1A CTD PMID:29154782