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Gene: Il1b (interleukin 1 beta) Rattus norvegicus
Symbol: Il1b
Name: interleukin 1 beta
RGD ID: 2891
Description: Exhibits cytokine activity. Involved in several processes, including positive regulation of intracellular signal transduction; regulation of nervous system development; and response to monosaccharide. Localizes to extracellular space. Used to study several diseases, including artery disease (multiple); brain disease (multiple); glomerulonephritis (multiple); interstitial lung disease (multiple); and kidney failure (multiple). Biomarker of several diseases, including artery disease (multiple); auditory system disease (multiple); brain disease (multiple); kidney failure (multiple); and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); blood platelet disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Orthologous to human IL1B (interleukin 1 beta); PARTICIPATES IN pro-inflammatory cytokine mediated pathway; interleukin-1 signaling pathway; interleukin-12 signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-pilocarpine; (+)-Tetrandrine.
Type: protein-coding
Also known as: IL-1 beta; IL-1F2; interleukin-1 beta
Homo sapiens (human) : IL1B (interleukin 1 beta)  HGNC  Alliance
Mus musculus (house mouse) : Il1b (interleukin 1 beta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il1b (interleukin 1 beta)
Pan paniscus (bonobo/pygmy chimpanzee) : IL1B (interleukin 1 beta)
Canis lupus familiaris (dog) : IL1B (interleukin 1 beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il1b (interleukin 1 beta)
Sus scrofa (pig) : LOC110258578 (interleukin-1 beta-like)
Chlorocebus sabaeus (African green monkey) : IL1B (interleukin 1 beta)
Heterocephalus glaber (naked mole-rat) : Il1b (interleukin 1 beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03121,876,256 - 121,882,637 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3121,876,263 - 121,882,726 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03128,133,929 - 128,140,354 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43116,964,422 - 116,970,867 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13116,869,999 - 116,876,460 (-)NCBI
Celera3115,403,045 - 115,409,735 (-)NCBICelera
Cytogenetic Map3q36NCBI
RH 3.4 Map31000.1RGD
JBrowse: View Region in Genome Browser (JBrowse)