IL1B (interleukin 1 beta) - Rat Genome Database

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Gene: IL1B (interleukin 1 beta) Canis lupus familiaris
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Symbol: IL1B
Name: interleukin 1 beta
RGD ID: 12192059
Description: ENCODES a protein that exhibits cytokine activity (ortholog); integrin binding (ortholog); INVOLVED IN acute inflammatory response (ortholog); astrocyte activation (ortholog); cellular response to antibiotic (ortholog); PARTICIPATES IN interleukin-1 signaling pathway; interleukin-12 signaling pathway; interleukin-23 signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); acute kidney failure (ortholog); Acute Lung Injury (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog); secretory granule (ortholog); INTERACTS WITH nimesulide; ochratoxin A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: IL-1; IL-1 beta; interleukin-1 beta; interleukin-1 beta proprotein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11737,019,329 - 37,033,388 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1737,019,329 - 37,024,458 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1736,788,618 - 36,793,136 (-)NCBI
ROS_Cfam_1.01737,794,784 - 37,800,390 (-)NCBI
UMICH_Zoey_3.11736,930,880 - 36,935,397 (-)NCBI
UNSW_CanFamBas_1.01736,987,147 - 36,991,665 (-)NCBI
UU_Cfam_GSD_1.01737,201,034 - 37,205,552 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (ISO)
acute kidney failure  (ISO)
Acute Lung Injury  (ISO)
Acute Necrotizing Pancreatitis  (ISO)
adenocarcinoma  (ISO)
adult respiratory distress syndrome  (ISO)
agranulocytosis  (ISO)
AIDS Dementia Complex  (ISO)
Albuminuria  (ISO)
Alcoholic Liver Diseases  (ISO)
allergic conjunctivitis  (ISO)
allergic disease  (ISO)
allergic rhinitis  (ISO)
Alport syndrome  (ISO)
Alzheimer's disease  (ISO)
anemia  (ISO)
Animal Disease Models  (ISO)
Anorexia  (ISO)
anthracosis  (ISO)
anthrax disease  (ISO)
anti-basement membrane glomerulonephritis  (ISO)
antisynthetase syndrome  (ISO)
Arsenic Poisoning  (ISO)
arteriosclerosis  (ISO)
asbestosis  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
atopic dermatitis  (ISO)
atrophic gastritis  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
bacterial pneumonia  (ISO)
Behcet's disease  (ISO)
brain infarction  (ISO)
Brain Injuries  (ISO)
Brain Injuries, Traumatic  (ISO)
brain ischemia  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
Bronchial Hyperreactivity  (ISO)
bronchiectasis  (ISO)
bronchiolitis  (ISO)
Bronchopulmonary Dysplasia  (ISO)
Burns  (ISO)
Burns, Chemical  (ISO)
Cachexia  (ISO)
calcinosis  (ISO)
Cardiomegaly  (ISO)
cardiomyopathy  (ISO)
Cardiotoxicity  (ISO)
cervical cancer  (ISO)
cervix uteri carcinoma in situ  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
cholesteatoma  (ISO)
chronic kidney disease  (ISO)
chronic myeloid leukemia  (ISO)
chronic obstructive pulmonary disease  (ISO)
chronic progressive external ophthalmoplegia  (ISO)
cochlear disease  (ISO)
Cognitive Dysfunction  (ISO)
colitis  (ISO)
Colonic Neoplasms  (ISO)
common cold  (ISO)
congestive heart failure  (ISO)
Contrast-Induced Nephropathy  (ISO)
coronary artery disease  (ISO)
Coronary Disease  (ISO)
COVID-19  (ISO)
crescentic glomerulonephritis  (ISO)
cutaneous leishmaniasis  (ISO)
cystic fibrosis  (ISO)
cystitis  (ISO)
dental caries  (ISO)
dermatomyositis  (ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
disease of cellular proliferation  (ISO)
Drug Hypersensitivity Syndrome  (ISO)
Drug-Induced Agranulocytosis  (ISO)
Drug-Induced Immune Thrombocytopenia  (ISO)
dry eye syndrome  (ISO)
Eales Disease  (ISO)
Edema  (ISO)
encephalitis  (ISO)
end stage renal disease  (ISO)
endophthalmitis  (ISO)
Endotoxemia  (ISO)
Entamoebiasis  (ISO)
Enterocolitis  (ISO)
epididymitis  (ISO)
epilepsy  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Neuritis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Melanoma  (ISO)
Experimental Pancreatitis, Chronic  (ISO)
extrahepatic cholestasis  (ISO)
extrinsic allergic alveolitis  (ISO)
Eye Burns  (ISO)
eye disease  (ISO)
familial Mediterranean fever  (ISO)
fatty liver disease  (ISO)
Febrile Seizures  (ISO)
Fever  (ISO)
Fibrosis  (ISO)
focal segmental glomerulosclerosis  (ISO)
Gallbladder Neoplasms  (ISO)
gastric adenocarcinoma  (ISO)
gastric dilatation  (ISO)
gastric ulcer  (ISO)
Genetic Predisposition to Disease  (ISO)
glioblastoma  (ISO)
glomerulonephritis  (ISO)
glomerulosclerosis  (ISO)
gout  (ISO)
Gram-Negative Bacterial Infections  (ISO)
Graves' disease  (ISO)
Heart Injuries  (ISO)
heart valve disease  (ISO)
Heat Stroke  (ISO)
Helicobacter Infections  (ISO)
hemolytic-uremic syndrome  (ISO)
Hemorrhagic Shock  (ISO)
hepatitis C  (ISO)
hepatocellular carcinoma  (ISO)
hereditary diffuse gastric cancer  (ISO)
herpes simplex virus keratitis  (ISO)
HIV Wasting Syndrome  (ISO)
Human Influenza  (ISO)
hydronephrosis  (ISO)
Hyperalgesia  (ISO)
Hypercholesterolemia  (ISO)
Hyperemia  (ISO)
hyperglycemia  (ISO)
hyperhomocysteinemia  (ISO)
hypertension  (ISO)
hypoglycemia  (ISO)
hypolipoproteinemia  (ISO)
Hypotension  (ISO)
Hypoxia-Ischemia, Brain  (ISO)
IgA glomerulonephritis  (ISO)
Inflammation  (ISO)
Insulin Resistance  (ISO)
Invasive Pulmonary Aspergillosis  (ISO)
Kawasaki disease  (ISO)
Kearns-Sayre syndrome  (ISO)
keratoconus  (ISO)
kidney failure  (ISO)
Kidney Reperfusion Injury  (ISO)
learning disability  (ISO)
Leber hereditary optic neuropathy  (ISO)
leptospirosis  (ISO)
Lethargy  (ISO)
Leukocytosis  (ISO)
Liver Reperfusion Injury  (ISO)
lung disease  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
Lung Reperfusion Injury  (ISO)
lupus nephritis  (ISO)
Lyme Neuroborreliosis  (ISO)
lymphopenia  (ISO)
Manganese Poisoning  (ISO)
MELAS syndrome  (ISO)
membranoproliferative glomerulonephritis  (ISO)
membranous glomerulonephritis  (ISO)
Memory Disorders  (ISO)
mental depression  (ISO)
MERRF Syndrome  (ISO)
middle cerebral artery infarction  (ISO)
Middle East respiratory syndrome  (ISO)
mitochondrial myopathy  (ISO)
mucositis  (ISO)
multiple myeloma  (ISO)
Multiple Organ Failure  (ISO)
multiple sclerosis  (ISO)
muscular disease  (ISO)
myelodysplastic syndrome  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
Necrosis  (ISO)
Neoplasm Invasiveness  (ISO)
nephrosis  (ISO)
nephrotic syndrome  (ISO)
neutropenia  (ISO)
Neutropenic Enterocolitis  (ISO)
non-alcoholic fatty liver disease  (ISO)
obesity  (ISO)
obstructive sleep apnea  (ISO)
osteoarthritis  (ISO)
osteoporosis  (ISO)
otitis media  (ISO)
Otitis Media with Effusion  (ISO)
pancreatic cancer  (ISO)
Pancreatic Cyst  (ISO)
pancreatitis  (ISO)
PAPA syndrome  (ISO)
paracoccidioidomycosis  (ISO)
Parkinson's disease  (ISO)
Parkinsonism  (ISO)
peptic ulcer disease  (ISO)
perinatal necrotizing enterocolitis  (ISO)
periodontitis  (ISO)
Peripheral Nerve Injuries  (ISO)
plague  (ISO)
pleural tuberculosis  (ISO)
pleurisy  (ISO)
pneumonia  (ISO)
polymyositis  (ISO)
polyneuropathy  (ISO)
portal hypertension  (ISO)
Postmenopausal Osteoporosis  (ISO)
Postoperative Cognitive Dysfunction  (ISO)
Presenile and Senile Dementia  (ISO)
Pseudomonas Aeruginosa Keratitis  (ISO)
Pseudomonas Infections  (ISO)
psoriasis  (ISO)
pulmonary edema  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
pulmonary tuberculosis  (ISO)
Radiation Injuries, Experimental  (ISO)
Reperfusion Injury  (ISO)
respiratory allergy  (ISO)
Retina Reperfusion Injury  (ISO)
retinal vein occlusion  (ISO)
retinitis  (ISO)
retinopathy of prematurity  (ISO)
rheumatoid arthritis  (ISO)
rhinitis  (ISO)
Rhinosinusitis  (ISO)
schizophrenia  (ISO)
sciatic neuropathy  (ISO)
Sepsis  (ISO)
severe acute respiratory syndrome  (ISO)
shigellosis  (ISO)
silicosis  (ISO)
sinusitis  (ISO)
skin disease  (ISO)
sleep disorder  (ISO)
Small-For-Size Syndrome  (ISO)
Spinal Cord Injuries  (ISO)
Spontaneous Abortions  (ISO)
Staphylococcal Pneumonia  (ISO)
status asthmaticus  (ISO)
status epilepticus  (ISO)
stomach cancer  (ISO)
Stomach Neoplasms  (ISO)
Stroke  (ISO)
Subarachnoid Hemorrhage  (ISO)
Systemic Inflammatory Response Syndrome  (ISO)
systemic lupus erythematosus  (ISO)
systemic scleroderma  (ISO)
thalassemia  (ISO)
thrombocytopenia  (ISO)
thrombocytosis  (ISO)
Thyroid Neoplasms  (ISO)
toxic shock syndrome  (ISO)
transient cerebral ischemia  (ISO)
Transplant Rejection  (ISO)
trigeminal neuralgia  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
ureteral obstruction  (ISO)
urinary bladder cancer  (ISO)
urinary tract infection  (ISO)
urticaria  (ISO)
uveitis  (ISO)
varicocele  (ISO)
vascular dementia  (ISO)
Venous Thrombosis  (ISO)
Ventilator-Induced Lung Injury  (ISO)
viral pneumonia  (ISO)
visceral leishmaniasis  (ISO)
visual epilepsy  (ISO)
Vulvar Vestibulitis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
nimesulide  (EXP)
ochratoxin A  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acute inflammatory response  (ISO)
astrocyte activation  (ISO)
cellular response to antibiotic  (ISO)
cellular response to drug  (ISO)
cellular response to fatty acid  (ISO)
cellular response to glucose stimulus  (ISO)
cellular response to lipid  (ISO)
cellular response to lipopolysaccharide  (IBA,ISO)
cellular response to mechanical stimulus  (IEA)
cellular response to organic cyclic compound  (IEA)
cellular response to organic substance  (ISO)
chronic inflammatory response to antigenic stimulus  (ISO)
cytokine-mediated signaling pathway  (IBA)
ectopic germ cell programmed cell death  (ISO)
extrinsic apoptotic signaling pathway in absence of ligand  (ISO)
fever generation  (IEA,ISO)
hyaluronan biosynthetic process  (IEA)
immune response  (IEA)
inflammatory response  (IBA)
interleukin-1-mediated signaling pathway  (IEA)
learning or memory  (ISO)
leukocyte migration  (ISO)
lipopolysaccharide-mediated signaling pathway  (IEA)
MAPK cascade  (IEA)
memory  (ISO)
monocyte aggregation  (IEA)
negative regulation of adiponectin secretion  (ISO)
negative regulation of branching morphogenesis of a nerve  (ISO)
negative regulation of cell population proliferation  (IEA)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (IEA)
negative regulation of gap junction assembly  (IEA)
negative regulation of gene expression  (ISO)
negative regulation of glucose transmembrane transport  (ISO)
negative regulation of glutamate secretion  (ISO)
negative regulation of insulin receptor signaling pathway  (ISO)
negative regulation of lipid catabolic process  (IEA)
negative regulation of lipid metabolic process  (ISO)
negative regulation of MAP kinase activity  (ISO)
negative regulation of neural precursor cell proliferation  (ISO)
negative regulation of neurogenesis  (ISO)
negative regulation of neuron differentiation  (ISO)
negative regulation of synaptic transmission  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
neutrophil chemotaxis  (ISO)
obsolete activation of MAPK activity  (IEA)
ovulation  (ISO)
positive regulation of angiogenesis  (IEA)
positive regulation of apoptotic process  (ISO)
positive regulation of astrocyte differentiation  (ISO)
positive regulation of calcidiol 1-monooxygenase activity  (IEA)
positive regulation of cell death  (ISO)
positive regulation of cell division  (IEA)
positive regulation of cell migration  (IEA)
positive regulation of cell population proliferation  (ISO)
positive regulation of chemokine production  (ISO)
positive regulation of complement activation  (IEA)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of DNA-binding transcription factor activity  (ISO)
positive regulation of epithelial to mesenchymal transition  (IEA)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of fever generation  (ISO)
positive regulation of gene expression  (IBA,ISO)
positive regulation of glial cell differentiation  (ISO)
positive regulation of glial cell proliferation  (IEA)
positive regulation of granulocyte macrophage colony-stimulating factor production  (IEA)
positive regulation of heterotypic cell-cell adhesion  (IEA)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (ISO)
positive regulation of immature T cell proliferation in thymus  (IBA,ISO)
positive regulation of inflammatory response  (IEA)
positive regulation of interferon-gamma production  (IEA,ISS)
positive regulation of interleukin-2 production  (IEA)
positive regulation of interleukin-6 production  (IEA,ISO)
positive regulation of interleukin-8 production  (IEA)
positive regulation of JNK cascade  (ISO)
positive regulation of JUN kinase activity  (ISO)
positive regulation of lipid catabolic process  (ISO)
positive regulation of membrane protein ectodomain proteolysis  (IEA)
positive regulation of mitotic nuclear division  (IEA)
positive regulation of monocyte chemotactic protein-1 production  (IEA)
positive regulation of myosin light chain kinase activity  (IEA)
positive regulation of neuron apoptotic process  (ISO)
positive regulation of neutrophil chemotaxis  (ISO)
positive regulation of NF-kappaB transcription factor activity  (IEA,ISO)
positive regulation of NIK/NF-kappaB signaling  (IEA)
positive regulation of nitric oxide biosynthetic process  (IEA)
positive regulation of p38MAPK cascade  (ISO)
positive regulation of phagocytosis  (IEA)
positive regulation of prostaglandin biosynthetic process  (IEA)
positive regulation of prostaglandin secretion  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of RNA biosynthetic process  (ISO)
positive regulation of stress-activated MAPK cascade  (ISO)
positive regulation of T cell proliferation  (IEA)
positive regulation of T-helper 1 cell cytokine production  (IEA,ISS)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription, DNA-templated  (IEA)
positive regulation of vascular endothelial growth factor production  (IEA)
protein kinase B signaling  (IEA)
regulation of defense response to virus by host  (ISO)
regulation of ERK1 and ERK2 cascade  (IEA)
regulation of establishment of endothelial barrier  (IEA)
regulation of I-kappaB kinase/NF-kappaB signaling  (IEA)
regulation of insulin secretion  (IEA)
regulation of neurogenesis  (ISO)
regulation of nitric-oxide synthase activity  (IBA,IEA)
response to ATP  (ISO)
response to carbohydrate  (ISO)
response to dexamethasone  (ISO)
response to drug  (ISO)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to gamma radiation  (ISO)
response to glucocorticoid  (ISO)
response to heat  (ISO)
response to hypoxia  (ISO)
response to immobilization stress  (ISO)
response to interleukin-1  (ISO)
response to L-ascorbic acid  (ISO)
response to lipopolysaccharide  (ISO)
response to morphine  (ISO)
response to nutrient  (ISO)
response to organic cyclic compound  (ISO)
response to organonitrogen compound  (ISO)
response to ozone  (ISO)
response to peptide hormone  (ISO)
response to stilbenoid  (ISO)
response to vitamin D  (ISO)
sequestering of triglyceride  (IEA)
signal transduction  (IEA)
social behavior  (ISO)
vascular endothelial growth factor production  (IEA,ISS)
wound healing  (ISO)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:16022989   PMID:16893658   PMID:17573384   PMID:18343681   PMID:19008121   PMID:22483380   PMID:23978557   PMID:24464937   PMID:26239893   PMID:26549149   PMID:26824356   PMID:27851800  


Genomics

Comparative Map Data
IL1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11737,019,329 - 37,033,388 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1737,019,329 - 37,024,458 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1736,788,618 - 36,793,136 (-)NCBI
ROS_Cfam_1.01737,794,784 - 37,800,390 (-)NCBI
UMICH_Zoey_3.11736,930,880 - 36,935,397 (-)NCBI
UNSW_CanFamBas_1.01736,987,147 - 36,991,665 (-)NCBI
UU_Cfam_GSD_1.01737,201,034 - 37,205,552 (-)NCBI
IL1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2112,829,751 - 112,836,816 (-)EnsemblGRCh38hg38GRCh38
GRCh382112,829,751 - 112,836,843 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372113,587,328 - 113,594,356 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,303,808 - 113,310,827 (-)NCBINCBI36hg18NCBI36
Build 342113,303,567 - 113,310,587NCBI
Celera2106,972,536 - 106,979,555 (-)NCBI
Cytogenetic Map2q14.1NCBI
HuRef2106,041,964 - 106,048,983 (-)NCBIHuRef
CHM1_12113,591,491 - 113,598,510 (-)NCBICHM1_1
Il1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392129,206,490 - 129,213,059 (-)NCBIGRCm39mm39
GRCm39 Ensembl2129,206,490 - 129,213,059 (-)Ensembl
GRCm382129,364,569 - 129,371,164 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2129,364,570 - 129,371,139 (-)EnsemblGRCm38mm10GRCm38
MGSCv372129,190,315 - 129,196,856 (-)NCBIGRCm37mm9NCBIm37
MGSCv362129,056,020 - 129,062,561 (-)NCBImm8
Celera2130,592,096 - 130,598,637 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.97NCBI
Il1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23116,577,005 - 116,583,386 (-)NCBI
Rnor_6.0 Ensembl3121,876,263 - 121,882,726 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.03121,876,256 - 121,882,637 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03128,133,929 - 128,140,354 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43116,964,422 - 116,970,867 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13116,869,999 - 116,876,460 (-)NCBI
Celera3115,403,045 - 115,409,735 (-)NCBICelera
RH 3.4 Map31000.1RGD
Cytogenetic Map3q36NCBI
Il1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554701,486,967 - 1,491,947 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554701,486,936 - 1,491,888 (+)NCBIChiLan1.0ChiLan1.0
IL1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A113,846,299 - 113,853,424 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A113,846,306 - 113,853,424 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A89,216,313 - 89,223,358 (+)NCBIMhudiblu_PPA_v0panPan3
Il1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629282,357,182 - 82,363,416 (-)NCBI
SpeTri2.0NW_0049367831,251,678 - 1,256,807 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC110258578
(Sus scrofa - pig)
No map positions available.
IL1B
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11415,844,628 - 15,852,652 (-)NCBI
ChlSab1.1 Ensembl1415,844,672 - 15,850,729 (-)Ensembl
Vero_WHO_p1.0NW_0236660803,810,298 - 3,839,365 (+)NCBI
Il1b
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474912,852,128 - 12,858,478 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 7 3 6 3 1 2 8 6 1
Below cutoff 5 5 15 3 3 5 3 9 4 5

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001037971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005630074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022404323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038690464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF322077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF322078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF349533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ251036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ923807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU074770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU249360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF477323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z70047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000011613   ⟹   ENSCAFP00000010762
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1737,019,329 - 37,024,176 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000067445   ⟹   ENSCAFP00000053594
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1737,019,472 - 37,024,458 (-)Ensembl
RefSeq Acc Id: NM_001037971   ⟹   NP_001033060
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11737,019,472 - 37,023,990 (-)NCBI
Dog10K_Boxer_Tasha1736,788,618 - 36,793,136 (-)NCBI
ROS_Cfam_1.01737,795,368 - 37,799,886 (-)NCBI
UMICH_Zoey_3.11736,930,880 - 36,935,397 (-)NCBI
UNSW_CanFamBas_1.01736,987,147 - 36,991,665 (-)NCBI
UU_Cfam_GSD_1.01737,201,034 - 37,205,552 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005630074   ⟹   XP_005630131
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11737,019,329 - 37,025,790 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022404323   ⟹   XP_022260031
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11737,019,329 - 37,033,388 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038690464   ⟹   XP_038546392
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01737,794,784 - 37,800,390 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_005630131   ⟸   XM_005630074
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001033060   ⟸   NM_001037971
- UniProtKB: Q2VCE2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022260031   ⟸   XM_022404323
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCAFP00000010762   ⟸   ENSCAFT00000011613
RefSeq Acc Id: ENSCAFP00000053594   ⟸   ENSCAFT00000067445
RefSeq Acc Id: XP_038546392   ⟸   XM_038690464
- Peptide Label: isoform X1
Protein Domains
IL1_propep


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007249 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000010762 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFP00000053594 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000011613 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFT00000067445 UniProtKB/TrEMBL
InterPro IL-1_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_propep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1/FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:403974 UniProtKB/TrEMBL
NCBI Gene IL1B ENTREZGENE
PANTHER PTHR10078 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10078:SF30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1_propep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS INTERLEUKIN1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE INTERLEUKIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50353 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A5K1UN28_CANLF UniProtKB/TrEMBL
  A7UJ07_CANLF UniProtKB/TrEMBL
  IL1B_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
  Q2VCE2 ENTREZGENE, UniProtKB/TrEMBL
  Q9GK42_CANLF UniProtKB/TrEMBL
  Q9GK43_CANLF UniProtKB/TrEMBL
UniProt Secondary F1PTU3 UniProtKB/TrEMBL
  Q006K6 UniProtKB/Swiss-Prot
VGNC ID VGNC:41957 ENTREZGENE