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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:2430
Term: aconitine
Definition: A diterpenoid that is 20-ethyl-3alpha,13,15alpha-trihydroxy-1alpha,6alpha,16beta-trimethoxy-4-(methoxymethyl)aconitane-8,14alpha-diol having acetate and benzoate groups at the 8- and 14-positions respectively.
Chemical ID: MESH:D000157
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bincreases expressionEXP 6480464CTDAconitine results in increased expression of IL1B proteinPMID:33236894
Il1bmultiple interactionsEXP 6480464CTDNLRP3 protein affects the reaction [Aconitine results in increased expression of IL1B protein]; NOD1 protein affects the reaction [Aconitine results in increased expression of IL1B protein]; NOD2 protein affects the reaction [Aconitine results in increased expression of IL1B protein]PMID:33236894
Il1bincreases expressionISOIl1b (Mus musculus)6480464CTDAconitine results in increased expression of IL1B proteinPMID:33236894
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