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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:15930
Term: atrazine
Definition: A diamino-1,3,5-triazine that is 1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6 while one of hydrogens of each amino group is replaced respectively by an ethyl and a propan-2-yl group.
Chemical ID: MESH:D001280
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bincreases expressionEXP 6480464CTDAtrazine results in increased expression of IL1B proteinPMID:34624533
Il1bincreases expressionISOIl1b (Mus musculus)6480464CTDAtrazine results in increased expression of IL1B mRNA; Atrazine results in increased expression of IL1B proteinPMID:26256823 PMID:36216167
Il1bincreases secretionISOIl1b (Mus musculus)6480464CTDAtrazine results in increased secretion of IL1B proteinPMID:34624533
Il1bmultiple interactionsISOIl1b (Mus musculus)6480464CTDLycopene inhibits the reaction [Atrazine results in increased expression of IL1B mRNA]PMID:36216167
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