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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:23527
Term: cytochalasin B
Definition: An organic heterotricyclic compound, that is a mycotoxin which is cell permeable an an inhibitor of cytoplasmic division by blocking the formation of contractile microfilaments.
Chemical ID: MESH:D003571
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bmultiple interactionsISORGD:7309816480464CTDCytochalasin B inhibits the reaction [[Alum Compounds co-treated with K-12 lipopolysaccharide] results in increased secretion of IL1B protein modified form] Cytochalasin B inhibits the reaction [Asbestos Crocidolite promotes the reaction [IL1B protein results in increased abundance of Nitric Oxide]] Cytochalasin B inhibits the reaction [Asbestos Serpentine promotes the reaction [IL1B protein results in increased abundance of Nitric Oxide]]

PMID:17404311 PMID:9698594
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