GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | decreases expression | EXP | | 6480464 | CTD | Sulindac results in decreased expression of IL1B protein | PMID:15123337 | Il1b | increases expression | EXP | | 6480464 | CTD | Sulindac results in increased expression of IL1B | PMID:24136188 | Il1b | decreases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Sulindac results in decreased expression of IL1B mRNA | PMID:10328874 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | [Sulindac co-treated with epigallocatechin gallate] results in decreased expression of IL1B mRNA; Sulindac inhibits the reaction [IL1B protein results in increased abundance of Hyaluronic Acid]; Sulindac inhibits the reaction [IL1B protein results in increased expression of CCL5 mRNA] | PMID:11318944 PMID:12628509 PMID:16159934 | |
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