IL1B (interleukin 1 beta) - Rat Genome Database

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Gene: IL1B (interleukin 1 beta) Homo sapiens
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Symbol: IL1B
Name: interleukin 1 beta
RGD ID: 730981
HGNC Page HGNC
Description: Enables cytokine activity; integrin binding activity; and protein domain specific binding activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of nitrogen compound metabolic process; and regulation of signal transduction. Acts upstream of or within cellular response to organic substance and cellular response to xenobiotic stimulus. Located in extracellular space. Implicated in several diseases, including autoimmune disease (multiple); blood platelet disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Biomarker of several diseases, including artery disease (multiple); autoimmune disease (multiple); bronchial disease (multiple); lung disease (multiple); and nose disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: catabolin; IL-1; IL-1 beta; IL1-BETA; IL1beta; IL1F2; interleukin 1, beta; interleukin 1beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in cytokine storm inflammatory response.
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2112,829,751 - 112,836,816 (-)EnsemblGRCh38hg38GRCh38
GRCh382112,829,751 - 112,836,843 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372113,587,328 - 113,594,356 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,303,808 - 113,310,827 (-)NCBINCBI36hg18NCBI36
Build 342113,303,567 - 113,310,587NCBI
Celera2106,972,536 - 106,979,555 (-)NCBI
Cytogenetic Map2q14.1NCBI
HuRef2106,041,964 - 106,048,983 (-)NCBIHuRef
CHM1_12113,591,491 - 113,598,510 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model