IL1B (interleukin 1 beta) - Rat Genome Database

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Gene: IL1B (interleukin 1 beta) Homo sapiens
Symbol: IL1B
Name: interleukin 1 beta
RGD ID: 730981
HGNC Page HGNC:5992
Description: Enables cytokine activity; integrin binding activity; and protein domain specific binding activity. Involved in several processes, including positive regulation of cellular biosynthetic process; regulation of signal transduction; and response to bacterium. Acts upstream of or within cellular response to organic substance; cellular response to xenobiotic stimulus; and positive regulation of interleukin-6 production. Located in extracellular region. Is active in extracellular space. Implicated in several diseases, including autoimmune disease (multiple); blood platelet disease (multiple); cervix disease (multiple); eye disease (multiple); and lung disease (multiple). Biomarker of several diseases, including artery disease (multiple); autoimmune disease (multiple); bronchial disease (multiple); lung disease (multiple); and nose disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: catabolin; IL-1; IL-1 beta; IL1-BETA; IL1beta; IL1F2; interleukin 1, beta; interleukin 1beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in cytokine storm inflammatory response.
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382112,829,751 - 112,836,779 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2112,829,751 - 112,836,816 (-)EnsemblGRCh38hg38GRCh38
GRCh372113,587,328 - 113,594,356 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,303,808 - 113,310,827 (-)NCBINCBI36Build 36hg18NCBI36
Build 342113,303,567 - 113,310,587NCBI
Celera2106,972,536 - 106,979,555 (-)NCBICelera
Cytogenetic Map2q14.1NCBI
HuRef2106,041,964 - 106,048,983 (-)NCBIHuRef
CHM1_12113,591,491 - 113,598,510 (-)NCBICHM1_1
T2T-CHM13v2.02113,256,242 - 113,263,270 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)