GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | increases expression | ISO | Il1b (Mus musculus) | 6480464 | CTD | 3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of IL1B mRNA; 3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of IL1B protein | PMID:30825315 PMID:37544346 | Il1b | increases secretion | ISO | Il1b (Mus musculus) | 6480464 | CTD | 3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased secretion of IL1B protein | PMID:38104874 | Il1b | multiple interactions | ISO | Il1b (Mus musculus) | 6480464 | CTD | [NFE2L2 gene mutant form results in increased susceptibility to 3,5-diethoxycarbonyl-1,4-dihydrocollidine] which results in increased expression of IL1B protein; cucurbitacin B inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased secretion of IL1B protein]; fuzheng huayu inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of IL1B mRNA]; fuzheng huayu inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of IL1B protein]; NFE2L2 gene mutant form promotes the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of IL1B mRNA]; Ursodeoxycholic Acid inhibits the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased secretion of IL1B protein] | PMID:30825315 PMID:37544346 PMID:38104874 | | ||||||||||||||||||||||
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