Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:15600
Term: (+)-catechin
Definition: The (+)-enantiomer of catechin and a polyphenolic antioxidant plant metabolite.
Chemical ID: MESH:D002392
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bmultiple interactionsEXP 6480464CTDCatechin inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]PMID:35337893
Il1bdecreases expressionISOIl1b (Mus musculus)6480464CTDCatechin results in decreased expression of IL1B proteinPMID:34581093
Il1bmultiple interactionsISOIL1B (Homo sapiens)6480464CTD[epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Catechin analog inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Catechin inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; Catechin inhibits the reaction [Glucose results in increased expression of IL1B protein]; Catechin inhibits the reaction [S100B protein results in increased expression of IL1B mRNA]PMID:17103373 PMID:19557821 PMID:26187476
Go Back to source page   Continue to Ontology report