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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:131358
Term: BAY 60-6583
Definition: A member of the class of cyanopyridines that is 6-amino-3,5-dicyano-4-(4-hydroxyphenyl)-2-sulfanylpyridine in which the hydroxy and sulfanyl hydrogens are replaced by cyclopropylmethyl and carboxamidomethyl groups respectively.
Chemical ID: MESH:C518875
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bdecreases expressionISOIl1b (Mus musculus)6480464CTDBAY 60-6583 results in decreased expression of IL1B mRNAPMID:35143882
Il1bmultiple interactionsISOIl1b (Mus musculus)6480464CTDBAY 60-6583 inhibits the reaction [Ethanol results in increased expression of IL1B mRNA]; BAY 60-6583 inhibits the reaction [Ethanol results in increased expression of IL1B protein]PMID:35143882
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