GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | increases secretion | EXP | | 6480464 | CTD | Ammonia results in increased secretion of IL1B protein | PMID:23284918 | Il1b | multiple interactions | EXP | | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Ammonia results in increased secretion of IL1B protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Ammonia results in increased secretion of IL1B protein]; Resveratrol inhibits the reaction [Ammonia results in increased secretion of IL1B protein] | PMID:23284918 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | IL1B protein inhibits the reaction [Ammonia results in decreased expression of AQP4 mRNA]; IL1B protein promotes the reaction [Ammonia results in decreased expression of GFAP mRNA]; IL1B protein promotes the reaction [Ammonia results in increased expression of HMOX1 mRNA]; IL1B protein promotes the reaction [Ammonia results in increased expression of NOS2 mRNA] | PMID:20217200 | | ||||||||||||||||||||||
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