GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | decreases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | alpha-naphthoflavone results in decreased expression of IL1B mRNA | PMID:22262711 | Il1b | increases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | alpha-naphthoflavone results in increased expression of IL1B mRNA | PMID:22262711 | Il1b | multiple interactions | ISO | Il1b (Mus musculus) | 6480464 | CTD | alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA] | PMID:27393915 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | alpha-naphthoflavone analog inhibits the reaction [IL1B protein results in increased expression of SAA1 mRNA]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1B protein] | PMID:14993811 PMID:15019843 PMID:18617548 PMID:21127131 PMID:22262711 | | ||||||||||||||||||||||
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