GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | decreases expression | ISO | Il1b (Mus musculus) | 6480464 | CTD | Sodium Selenite results in decreased expression of IL1B mRNA | PMID:25187657 | Il1b | increases expression | ISO | Il1b (Mus musculus) | 6480464 | CTD | Sodium Selenite results in increased expression of IL1B protein | PMID:10871427 | Il1b | multiple interactions | ISO | Il1b (Mus musculus) | 6480464 | CTD | N-TUTCA2 gene mutant form promotes the reaction [Sodium Selenite deficiency results in increased expression of IL1B mRNA]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] | PMID:18789669 PMID:25187657 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | IL1B protein promotes the reaction [Sodium Selenite results in increased expression of and results in increased activity of GPX4 protein]; IL1B protein promotes the reaction [Sodium Selenite results in increased expression of GPX4 mRNA] | PMID:14642406 | | ||||||||||||||||||||||
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