GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | multiple interactions | EXP | | 6480464 | CTD | Luteolin inhibits the reaction [[IL1B protein co-treated with IFNG protein] affects the localization of and results in increased activity of NFKB1 protein]; Luteolin inhibits the reaction [[IL1B protein co-treated with IFNG protein] affects the localization of and results in increased activity of RELA protein]; Luteolin inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in decreased secretion of INS1 protein]; Luteolin inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; Luteolin inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased degradation of NFKBIA protein]; Luteolin inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Luteolin inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; Luteolin inhibits the reaction [bisphenol A results in decreased expression of IL1B protein]; Luteolin inhibits the reaction [cobaltous chloride results in increased expression of IL1B protein]; Luteolin inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B protein]; Luteolin inhibits the reaction [lipoteichoic acid results in increased expression of IL1B] | PMID:18090225 PMID:20685402 PMID:25450234 PMID:31091348 PMID:31362009 | Il1b | decreases expression | ISO | Il1b (Mus musculus) | 6480464 | CTD | Luteolin results in decreased expression of IL1B protein | PMID:37563784 | Il1b | decreases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Luteolin results in decreased expression of IL1B mRNA | PMID:34699766 | Il1b | multiple interactions | ISO | Il1b (Mus musculus) | 6480464 | CTD | Luteolin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Luteolin inhibits the reaction [Rotenone results in increased secretion of IL1B protein] | PMID:30207190 PMID:37390879 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Luteolin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; Luteolin inhibits the reaction [chromium hexavalent ion results in increased secretion of IL1B protein]; Luteolin inhibits the reaction [decabromobiphenyl ether results in increased expression of IL1B protein]; Luteolin inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; Luteolin inhibits the reaction [Glucose results in increased expression of IL1B protein]; Luteolin inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein]; Luteolin inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]; Luteolin inhibits the reaction [Irinotecan results in increased expression of IL1B mRNA]; Luteolin inhibits the reaction [Irinotecan results in increased secretion of IL1B protein]; Luteolin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1B protein]; Luteolin inhibits the reaction [nickel chloride results in increased expression of IL1B protein] | PMID:18946510 PMID:19557821 PMID:24134915 PMID:25448439 PMID:30016632 PMID:33675858 PMID:34217685 PMID:34699766 | | ||||||||||||||||||||||
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