Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	2891
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Il1b
Name:	interleukin 1 beta

Acc ID:	CHEBI:4021
Term:	Cyclopamine
Definition:	A piperidine that has formula C27H41NO2.
Chemical ID:	MESH:C000541

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Il1b	decreases expression	ISO	IL1B (Homo sapiens)	6480464	CTD	cyclopamine results in decreased expression of IL1B mRNA	PMID:30578886

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.