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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:77131
Term: sinapic acid
Definition: A monohydroxycinnamic acid that is cinnamic acid in which the phenyl hydrogens at positions 3, 4, and 5 are replaced by methoxy, hydroxy, and methoxy groups, respectively.
Chemical ID: MESH:C073734
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bmultiple interactionsEXP 6480464CTD2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [sinapinic acid inhibits the reaction [Cisplatin results in increased expression of IL1B protein]]; sinapinic acid inhibits the reaction [Cisplatin results in increased expression of IL1B protein]; sinapinic acid inhibits the reaction [lead acetate results in increased expression of IL1B mRNA]; sinapinic acid inhibits the reaction [Methotrexate results in increased expression of IL1B protein]PMID:32742113 PMID:33720507 PMID:37471654
Il1bmultiple interactionsISOIl1b (Mus musculus)6480464CTDsinapinic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]PMID:18841975
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