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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:34288
Term: 2-hydroxyethyl methacrylate
Definition: An enoate ester that is the monomethacryloyl derivative of ethylene glycol.
Chemical ID: MESH:C005044
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bmultiple interactionsISOIl1b (Mus musculus)6480464CTD2-oxothiazolidine-4-carboxylic acid inhibits the reaction [hydroxyethyl methacrylate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; Buthionine Sulfoximine promotes the reaction [hydroxyethyl methacrylate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; hydroxyethyl methacrylate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; hydroxyethyl methacrylate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; hydroxyethyl methacrylate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; hydroxyethyl methacrylate promotes the reaction [triethylene glycol dimethacrylate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; triethylene glycol dimethacrylate promotes the reaction [hydroxyethyl methacrylate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]PMID:23182953 PMID:28188892
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