Atp7a Rat 1,1'-azobis(N,N-dimethylformamide) multiple interactions ISO RGD:10216 6480464 Diamide promotes the reaction [CLU protein binds to ATP7A protein] CTD PMID:21242307 Atp7a Rat 1,1-dichloroethene increases expression ISO RGD:10215 6480464 vinylidene chloride results in increased expression of ATP7A mRNA CTD PMID:26682919 Atp7a Rat 1,2-dimethylhydrazine multiple interactions EXP 6480464 [APC protein affects the susceptibility to 1,2-Dimethylhydrazine] which results in increased expression of ATP7A mRNA CTD PMID:27840820 Atp7a Rat 1,2-dimethylhydrazine multiple interactions ISO RGD:10215 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP7A mRNA CTD PMID:22206623 Atp7a Rat 1,4-dithiothreitol multiple interactions ISO RGD:10216 6480464 Dithiothreitol inhibits the reaction [Ethylmaleimide results in increased glutathionylation of ATP7A protein] CTD PMID:20566629 Atp7a Rat 17alpha-ethynylestradiol multiple interactions ISO RGD:10215 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ATP7A mRNA CTD PMID:17942748 Atp7a Rat 17alpha-ethynylestradiol decreases expression ISO RGD:10215 6480464 Ethinyl Estradiol results in decreased expression of ATP7A mRNA; Ethinyl Estradiol results in decreased expression more ... CTD PMID:27690074 Atp7a Rat 17alpha-ethynylestradiol increases expression ISO RGD:10215 6480464 Ethinyl Estradiol results in increased expression of ATP7A mRNA CTD PMID:17942748 Atp7a Rat 2,2,2-tetramine increases expression EXP 6480464 Trientine results in increased expression of ATP7A mRNA; Trientine results in increased expression of ATP7A more ... CTD PMID:24927960 Atp7a Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10215 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ATP7A mRNA CTD PMID:17942748 Atp7a Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of ATP7A mRNA CTD PMID:32109520 Atp7a Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10215 6480464 Tetrachlorodibenzodioxin affects the expression of ATP7A mRNA CTD PMID:21570461 Atp7a Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:10215 6480464 Tetrachlorodibenzodioxin results in decreased expression of ATP7A mRNA CTD PMID:19770486|PMID:33956508 Atp7a Rat 2-hydroxypropanoic acid decreases expression ISO RGD:10216 6480464 Lactic Acid results in decreased expression of ATP7A mRNA CTD PMID:30851411 Atp7a Rat 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:10215 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of ATP7A mRNA CTD PMID:20188158|PMID:26251327 Atp7a Rat 4,4'-sulfonyldiphenol decreases methylation ISO RGD:10215 6480464 bisphenol S results in decreased methylation of ATP7A exon CTD PMID:33297965 Atp7a Rat 4-hydroxy-TEMPO multiple interactions ISO RGD:10215 6480464 tempol inhibits the reaction [ATP7A mutant form inhibits the reaction [AGT protein results in increased more ... CTD PMID:18768397 Atp7a Rat 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions ISO RGD:10216 6480464 Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein] CTD PMID:25337692 Atp7a Rat 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions ISO RGD:10215 6480464 Omeprazole inhibits the reaction [Copper affects the localization of ATP7A protein]; Omeprazole inhibits the reaction more ... CTD PMID:25337692 Atp7a Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of ATP7A mRNA CTD PMID:22504374 Atp7a Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of ATP7A mRNA CTD PMID:31881176 Atp7a Rat acetylcholine multiple interactions ISO RGD:10215 6480464 ATP7A mutant form inhibits the reaction [AGT protein results in increased susceptibility to Acetylcholine]; tempol more ... CTD PMID:18768397 Atp7a Rat aflatoxin B1 decreases methylation ISO RGD:10216 6480464 Aflatoxin B1 results in decreased methylation of ATP7A gene CTD PMID:27153756 Atp7a Rat Aflatoxin B2 alpha increases methylation ISO RGD:10216 6480464 aflatoxin B2 results in increased methylation of ATP7A intron CTD PMID:30157460 Atp7a Rat all-trans-retinoic acid increases expression ISO RGD:10216 6480464 Tretinoin results in increased expression of ATP7A mRNA CTD PMID:16012519|PMID:21934132 Atp7a Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of ATP7A mRNA CTD PMID:16483693 Atp7a Rat aristolochic acid A decreases expression ISO RGD:10216 6480464 aristolochic acid I results in decreased expression of ATP7A mRNA CTD PMID:33212167 Atp7a Rat arsenous acid decreases expression ISO RGD:10215 6480464 Arsenic Trioxide results in decreased expression of ATP7A mRNA CTD PMID:35676786 Atp7a Rat ATP multiple interactions ISO RGD:10216 6480464 [Copper co-treated with Adenosine Triphosphate] results in increased phosphorylation of ATP7A protein CTD PMID:20964302 Atp7a Rat atrazine decreases expression ISO RGD:10216 6480464 Atrazine results in decreased expression of ATP7A mRNA CTD PMID:22378314 Atp7a Rat Azoxymethane multiple interactions ISO RGD:10215 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ATP7A more ... CTD PMID:29950665 Atp7a Rat bathocuproine disulfonic acid multiple interactions ISO RGD:10216 6480464 [Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7A protein]; bathocuproine more ... CTD PMID:11092760|PMID:21242307 Atp7a Rat benzo[a]pyrene increases expression ISO RGD:10215 6480464 Benzo(a)pyrene results in increased expression of ATP7A mRNA CTD PMID:20504355|PMID:22228805 Atp7a Rat benzo[a]pyrene increases methylation ISO RGD:10216 6480464 Benzo(a)pyrene results in increased methylation of ATP7A exon CTD PMID:27901495 Atp7a Rat benzo[a]pyrene affects methylation ISO RGD:10216 6480464 Benzo(a)pyrene affects the methylation of ATP7A promoter CTD PMID:27901495 Atp7a Rat benzo[e]pyrene affects methylation ISO RGD:10216 6480464 benzo(e)pyrene affects the methylation of ATP7A intron CTD PMID:30157460 Atp7a Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of ATP7A mRNA CTD PMID:25181051 Atp7a Rat bisphenol A increases expression ISO RGD:10216 6480464 bisphenol A results in increased expression of ATP7A mRNA CTD PMID:29275510 Atp7a Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ATP7A mRNA CTD PMID:30816183|PMID:34947998 Atp7a Rat bisphenol A decreases expression ISO RGD:10215 6480464 bisphenol A results in decreased expression of ATP7A mRNA; bisphenol A results in decreased expression more ... CTD PMID:27690074 Atp7a Rat brefeldin A multiple interactions ISO RGD:10216 6480464 Brefeldin A inhibits the reaction [ATP7A protein affects the localization of Doxorubicin] CTD PMID:17510416 Atp7a Rat butanal decreases expression ISO RGD:10216 6480464 butyraldehyde results in decreased expression of ATP7A mRNA CTD PMID:26079696 Atp7a Rat cadmium atom decreases expression ISO RGD:10216 6480464 Cadmium results in decreased expression of ATP7A mRNA CTD PMID:24376830 Atp7a Rat cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of ATP7A mRNA; Cadmium results in increased expression of ATP7A more ... CTD PMID:32879253 Atp7a Rat cadmium dichloride decreases expression ISO RGD:10215 6480464 Cadmium Chloride results in decreased expression of ATP7A mRNA CTD PMID:24982889 Atp7a Rat cadmium dichloride decreases expression ISO RGD:10216 6480464 Cadmium Chloride results in decreased expression of ATP7A mRNA CTD PMID:38568856 Atp7a Rat carboplatin affects localization ISO RGD:10216 6480464 Carboplatin affects the localization of ATP7A protein CTD PMID:24150977 Atp7a Rat carboplatin multiple interactions ISO RGD:10216 6480464 [MIR495 mRNA results in decreased expression of ATP7A protein] which results in increased susceptibility to more ... CTD PMID:24038379|PMID:24150977 Atp7a Rat chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of ATP7A mRNA CTD PMID:23125180 Atp7a Rat chromium(6+) decreases expression ISO RGD:10216 6480464 chromium hexavalent ion results in decreased expression of ATP7A mRNA CTD PMID:30690063 Atp7a Rat cisplatin decreases response to substance ISO RGD:10215 6480464 ATP7A protein results in decreased susceptibility to Cisplatin CTD PMID:16170571 Atp7a Rat cisplatin decreases expression ISO RGD:10216 6480464 Cisplatin results in decreased expression of ATP7A mRNA CTD PMID:38462020 Atp7a Rat cisplatin decreases expression ISO RGD:10215 6480464 Cisplatin results in decreased expression of ATP7A CTD PMID:38462020 Atp7a Rat cisplatin affects localization ISO RGD:10216 6480464 Cisplatin affects the localization of ATP7A protein CTD PMID:24150977 Atp7a Rat cisplatin multiple interactions ISO RGD:10216 6480464 [ATOX1 protein binds to Cisplatin] promotes the reaction [ATP7A protein binds to and results in more ... CTD PMID:23751120|PMID:24038379|PMID:24150977 Atp7a Rat cisplatin affects response to substance ISO RGD:10216 6480464 ATP7A protein affects the susceptibility to Cisplatin CTD PMID:17609664 Atp7a Rat cisplatin decreases response to substance ISO RGD:10216 6480464 ATP7A protein results in decreased susceptibility to Cisplatin CTD PMID:17510416|PMID:25801007 Atp7a Rat cisplatin increases response to substance ISO RGD:10216 6480464 ATP7A mutant form results in increased susceptibility to Cisplatin CTD PMID:22304828 Atp7a Rat cisplatin increases expression ISO RGD:10215 6480464 Cisplatin results in increased expression of ATP7A mRNA CTD PMID:21151649 Atp7a Rat cobalt dichloride increases expression ISO RGD:10216 6480464 cobaltous chloride results in increased expression of ATP7A mRNA CTD PMID:24614111 Atp7a Rat cobalt dichloride multiple interactions EXP 6480464 Plicamycin inhibits the reaction [cobaltous chloride results in increased expression of ATP7A mRNA] CTD PMID:23814049 Atp7a Rat cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of ATP7A mRNA CTD PMID:23814049 Atp7a Rat copper atom affects metabolic processing ISO RGD:10216 6480464 ATP7A protein affects the metabolism of Copper CTD PMID:16890543 Atp7a Rat copper atom affects localization ISO RGD:10216 6480464 Copper affects the localization of ATP7A protein CTD PMID:20964302|PMID:23423674 Atp7a Rat copper atom decreases abundance ISO RGD:10215 6480464 ATP7A gene mutant form results in decreased abundance of Copper; ATP7A protein mutant form results more ... CTD PMID:21336677|PMID:23776592|PMID:25247420 Atp7a Rat copper atom increases transport EXP 6480464 ATP7A protein results in increased transport of Copper CTD PMID:24614235 Atp7a Rat copper atom affects localization EXP 6480464 Copper affects the localization of ATP7A protein CTD PMID:20671235|PMID:24614235 Atp7a Rat copper atom decreases export EXP 6480464 ATP7A mutant form results in decreased export of Copper CTD PMID:24316150 Atp7a Rat copper atom affects export ISO RGD:10215 6480464 ATP7A protein affects the export of Copper CTD PMID:21409224 Atp7a Rat copper atom increases export ISO RGD:10216 6480464 ATP7A protein results in increased export of Copper CTD PMID:16397091|PMID:17975309|PMID:18779306 Atp7a Rat copper atom increases abundance ISO RGD:10216 6480464 ATP7A gene mutant form results in increased abundance of Copper CTD PMID:15923132 Atp7a Rat copper atom decreases abundance ISO RGD:10216 6480464 ATP7A gene mutant form results in decreased abundance of Copper; ATP7A protein mutant form results more ... CTD PMID:11350187|PMID:14985339|PMID:15923132|PMID:24522273 Atp7a Rat copper atom multiple interactions ISO RGD:10215 6480464 [ATP7A gene mutant form co-treated with Iron deficiency] results in increased uptake of Copper; [ATP7A more ... CTD PMID:15467011|PMID:19351718|PMID:22089129|PMID:23776592|PMID:25337692 Atp7a Rat copper atom increases abundance ISO RGD:10215 6480464 ATP7A gene mutant form results in increased abundance of Copper CTD PMID:15467011 Atp7a Rat copper atom affects localization ISO RGD:10215 6480464 ATP7A gene mutant form affects the localization of Copper; Copper affects the localization of ATP7A more ... CTD PMID:17483305|PMID:20671235|PMID:22089129|PMID:25337692 Atp7a Rat copper atom increases transport ISO RGD:10216 6480464 ATP7A protein results in increased transport of Copper CTD PMID:21667063 Atp7a Rat copper atom increases expression EXP 6480464 Copper results in increased expression of ATP7A mRNA CTD PMID:15591161 Atp7a Rat copper atom multiple interactions EXP 6480464 [Iron deficiency results in increased expression of ATP7A] which results in increased abundance of Copper; more ... CTD PMID:16741141|PMID:24174620 Atp7a Rat copper atom increases secretion EXP 6480464 ATP7A protein results in increased secretion of Copper CTD PMID:16741141 Atp7a Rat copper atom affects transport ISO RGD:10216 6480464 ATP7A protein affects the transport of Copper CTD PMID:17109627 Atp7a Rat copper atom affects binding ISO RGD:10216 6480464 ATP7A protein binds to Copper; Copper binds to ATP7A protein CTD PMID:16873374|PMID:22577880 Atp7a Rat copper atom multiple interactions ISO RGD:10216 6480464 [ATP7A protein affects the oxidation of SCO1 protein] which affects the abundance of Copper; [COMMD1 more ... CTD PMID:10841766|PMID:17009961|PMID:17109627|PMID:19205902|PMID:19576997|PMID:20964302|PMID:20971185|PMID:21034850|PMID:21188142|PMID:21646353|PMID:21667063|PMID:23345593|PMID:23423674|PMID:32278528 Atp7a Rat copper(0) affects metabolic processing ISO RGD:10216 6480464 ATP7A protein affects the metabolism of Copper CTD PMID:16890543 Atp7a Rat copper(0) affects localization ISO RGD:10216 6480464 Copper affects the localization of ATP7A protein CTD PMID:20964302|PMID:23423674 Atp7a Rat copper(0) decreases abundance ISO RGD:10215 6480464 ATP7A gene mutant form results in decreased abundance of Copper; ATP7A protein mutant form results more ... CTD PMID:21336677|PMID:23776592|PMID:25247420 Atp7a Rat copper(0) increases transport EXP 6480464 ATP7A protein results in increased transport of Copper CTD PMID:24614235 Atp7a Rat copper(0) affects localization EXP 6480464 Copper affects the localization of ATP7A protein CTD PMID:20671235|PMID:24614235 Atp7a Rat copper(0) decreases export EXP 6480464 ATP7A mutant form results in decreased export of Copper CTD PMID:24316150 Atp7a Rat copper(0) affects export ISO RGD:10215 6480464 ATP7A protein affects the export of Copper CTD PMID:21409224 Atp7a Rat copper(0) increases export ISO RGD:10216 6480464 ATP7A protein results in increased export of Copper CTD PMID:16397091|PMID:17975309|PMID:18779306 Atp7a Rat copper(0) increases abundance ISO RGD:10216 6480464 ATP7A gene mutant form results in increased abundance of Copper CTD PMID:15923132 Atp7a Rat copper(0) decreases abundance ISO RGD:10216 6480464 ATP7A gene mutant form results in decreased abundance of Copper; ATP7A protein mutant form results more ... CTD PMID:11350187|PMID:14985339|PMID:15923132|PMID:24522273 Atp7a Rat copper(0) multiple interactions ISO RGD:10215 6480464 [ATP7A gene mutant form co-treated with Iron deficiency] results in increased uptake of Copper; [ATP7A more ... CTD PMID:15467011|PMID:19351718|PMID:22089129|PMID:23776592|PMID:25337692 Atp7a Rat copper(0) increases abundance ISO RGD:10215 6480464 ATP7A gene mutant form results in increased abundance of Copper CTD PMID:15467011 Atp7a Rat copper(0) affects localization ISO RGD:10215 6480464 ATP7A gene mutant form affects the localization of Copper; Copper affects the localization of ATP7A more ... CTD PMID:17483305|PMID:20671235|PMID:22089129|PMID:25337692 Atp7a Rat copper(0) increases transport ISO RGD:10216 6480464 ATP7A protein results in increased transport of Copper CTD PMID:21667063 Atp7a Rat copper(0) increases expression EXP 6480464 Copper results in increased expression of ATP7A mRNA CTD PMID:15591161 Atp7a Rat copper(0) multiple interactions EXP 6480464 [Iron deficiency results in increased expression of ATP7A] which results in increased abundance of Copper; more ... CTD PMID:16741141|PMID:24174620 Atp7a Rat copper(0) increases secretion EXP 6480464 ATP7A protein results in increased secretion of Copper CTD PMID:16741141 Atp7a Rat copper(0) affects transport ISO RGD:10216 6480464 ATP7A protein affects the transport of Copper CTD PMID:17109627 Atp7a Rat copper(0) affects binding ISO RGD:10216 6480464 ATP7A protein binds to Copper; Copper binds to ATP7A protein CTD PMID:16873374|PMID:22577880 Atp7a Rat copper(0) multiple interactions ISO RGD:10216 6480464 [ATP7A protein affects the oxidation of SCO1 protein] which affects the abundance of Copper; [COMMD1 more ... CTD PMID:10841766|PMID:17009961|PMID:17109627|PMID:19205902|PMID:19576997|PMID:20964302|PMID:20971185|PMID:21034850|PMID:21188142|PMID:21646353|PMID:21667063|PMID:23345593|PMID:23423674|PMID:32278528 Atp7a Rat copper(II) chloride increases transport ISO RGD:10216 6480464 ATP7A protein results in increased transport of cupric chloride CTD PMID:17009961 Atp7a Rat copper(II) chloride multiple interactions ISO RGD:10215 6480464 Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein] CTD PMID:25337692 Atp7a Rat copper(II) chloride affects localization ISO RGD:10215 6480464 cupric chloride affects the localization of ATP7A protein CTD PMID:16317117|PMID:25337692 Atp7a Rat copper(II) chloride decreases glutathionylation ISO RGD:10216 6480464 cupric chloride results in decreased glutathionylation of ATP7A protein CTD PMID:20566629 Atp7a Rat copper(II) chloride multiple interactions ISO RGD:10216 6480464 ATP7A protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper]; more ... CTD PMID:11092760|PMID:21242307|PMID:32278528 Atp7a Rat copper(II) chloride increases expression EXP 6480464 cupric chloride results in increased expression of ATP7A protein CTD PMID:23174565 Atp7a Rat copper(II) chloride multiple interactions EXP 6480464 cupric chloride inhibits the reaction [Cycloheximide results in decreased expression of ATP7A protein]; cupric chloride more ... CTD PMID:23174565 Atp7a Rat copper(II) sulfate increases expression ISO RGD:10216 6480464 Copper Sulfate results in increased expression of ATP7A protein CTD PMID:24815816 Atp7a Rat CU-O LINKAGE increases expression ISO RGD:10216 6480464 cupric oxide analog results in increased expression of ATP7A mRNA; cupric oxide analog results in more ... CTD PMID:24815816 Atp7a Rat cycloheximide decreases expression EXP 6480464 Cycloheximide results in decreased expression of ATP7A protein CTD PMID:23174565 Atp7a Rat cycloheximide multiple interactions EXP 6480464 cupric chloride inhibits the reaction [Cycloheximide results in decreased expression of ATP7A protein] CTD PMID:23174565 Atp7a Rat cyclosporin A decreases expression ISO RGD:10215 6480464 Cyclosporine results in decreased expression of ATP7A mRNA CTD PMID:19770486 Atp7a Rat cyclosporin A decreases expression ISO RGD:10216 6480464 Cyclosporine results in decreased expression of ATP7A mRNA CTD PMID:25562108 Atp7a Rat D-penicillamine multiple interactions ISO RGD:10216 6480464 [Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7A protein] CTD PMID:21242307 Atp7a Rat decabromodiphenyl ether decreases expression EXP 6480464 decabromobiphenyl ether results in decreased expression of ATP7A mRNA CTD PMID:23914054 Atp7a Rat desferrioxamine B increases expression EXP 6480464 Deferoxamine results in increased expression of ATP7A mRNA CTD PMID:23174565 Atp7a Rat desferrioxamine B multiple interactions EXP 6480464 cupric chloride promotes the reaction [Deferoxamine results in increased expression of ATP7A mRNA]; Deferoxamine promotes more ... CTD PMID:23174565 Atp7a Rat dextran sulfate multiple interactions ISO RGD:10215 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ATP7A more ... CTD PMID:29950665 Atp7a Rat diarsenic trioxide decreases expression ISO RGD:10215 6480464 Arsenic Trioxide results in decreased expression of ATP7A mRNA CTD PMID:35676786 Atp7a Rat Dibutyl phosphate affects expression ISO RGD:10216 6480464 di-n-butylphosphoric acid affects the expression of ATP7A mRNA CTD PMID:37042841 Atp7a Rat dibutyl phthalate increases expression ISO RGD:10215 6480464 Dibutyl Phthalate results in increased expression of ATP7A mRNA CTD PMID:21266533 Atp7a Rat dioxygen increases expression ISO RGD:10215 6480464 Oxygen deficiency results in increased expression of ATP7A mRNA; Oxygen deficiency results in increased expression more ... CTD PMID:19351718|PMID:24614111 Atp7a Rat dioxygen increases expression ISO RGD:10216 6480464 Oxygen deficiency results in increased expression of ATP7A mRNA CTD PMID:24614111 Atp7a Rat dioxygen affects localization ISO RGD:10215 6480464 Oxygen deficiency affects the localization of ATP7A protein CTD PMID:19351718 Atp7a Rat dioxygen multiple interactions ISO RGD:10215 6480464 tetrathiomolybdate inhibits the reaction [Oxygen deficiency affects the localization of ATP7A protein] CTD PMID:19351718 Atp7a Rat dorsomorphin multiple interactions ISO RGD:10216 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... CTD PMID:27188386 Atp7a Rat doxorubicin affects localization ISO RGD:10216 6480464 ATP7A protein affects the localization of Doxorubicin CTD PMID:17510416 Atp7a Rat doxorubicin decreases response to substance ISO RGD:10216 6480464 ATP7A protein results in decreased susceptibility to Doxorubicin CTD PMID:17510416 Atp7a Rat doxorubicin multiple interactions ISO RGD:10216 6480464 Brefeldin A inhibits the reaction [ATP7A protein affects the localization of Doxorubicin]; Monensin inhibits the more ... CTD PMID:17510416 Atp7a Rat doxorubicin increases export ISO RGD:10216 6480464 ATP7A protein results in increased export of Doxorubicin CTD PMID:17510416 Atp7a Rat entinostat decreases expression ISO RGD:10216 6480464 entinostat results in decreased expression of ATP7A mRNA CTD PMID:26272509 Atp7a Rat entinostat multiple interactions ISO RGD:10216 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... CTD PMID:27188386 Atp7a Rat ethyl methanesulfonate increases expression ISO RGD:10216 6480464 Ethyl Methanesulfonate results in increased expression of ATP7A mRNA CTD PMID:23649840 Atp7a Rat etoposide decreases response to substance ISO RGD:10216 6480464 ATP7A protein results in decreased susceptibility to Etoposide CTD PMID:17510416 Atp7a Rat folic acid multiple interactions ISO RGD:10215 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP7A mRNA CTD PMID:22206623 Atp7a Rat FR900359 affects phosphorylation ISO RGD:10216 6480464 FR900359 affects the phosphorylation of ATP7A protein CTD PMID:37730182 Atp7a Rat hexadecanoic acid increases phosphorylation ISO RGD:10216 6480464 Palmitic Acid results in increased phosphorylation of ATP7A protein CTD PMID:28073184 Atp7a Rat hydrogen peroxide multiple interactions ISO RGD:10216 6480464 ATP7A protein promotes the reaction [Paraquat results in increased chemical synthesis of Hydrogen Peroxide]; Hydrogen more ... CTD PMID:21242307|PMID:29058724 Atp7a Rat irinotecan decreases response to substance ISO RGD:10216 6480464 ATP7A protein results in decreased susceptibility to Irinotecan CTD PMID:17510416 Atp7a Rat irinotecan increases export ISO RGD:10216 6480464 ATP7A protein results in increased export of Irinotecan CTD PMID:17510416 Atp7a Rat iron atom increases expression EXP 6480464 Iron deficiency results in increased expression of ATP7A; Iron deficiency results in increased expression of more ... CTD PMID:16629162|PMID:21852364|PMID:23174565|PMID:23814049|PMID:24089420|PMID:24174620 Atp7a Rat iron atom affects metabolic processing ISO RGD:10215 6480464 ATP7A protein mutant form affects the metabolism of Iron CTD PMID:25247420 Atp7a Rat iron atom increases expression ISO RGD:10215 6480464 Iron deficiency results in increased expression of ATP7A mRNA CTD PMID:23776592|PMID:24089420 Atp7a Rat iron atom increases response to substance ISO RGD:10215 6480464 ATP7A gene mutant form results in increased susceptibility to Iron deficiency CTD PMID:23776592 Atp7a Rat iron atom affects transport EXP 6480464 ATP7A mutant form affects the transport of Iron CTD PMID:24174620 Atp7a Rat iron atom multiple interactions EXP 6480464 [Iron deficiency results in increased expression of ATP7A] which results in increased abundance of Copper CTD PMID:24174620 Atp7a Rat iron atom decreases oxidation ISO RGD:10215 6480464 ATP7A gene mutant form results in decreased oxidation of Iron CTD PMID:23776592 Atp7a Rat iron atom multiple interactions ISO RGD:10215 6480464 [ATP7A gene mutant form co-treated with Iron deficiency] results in increased uptake of Copper; [ATP7A more ... CTD PMID:23776592 Atp7a Rat iron(0) increases expression EXP 6480464 Iron deficiency results in increased expression of ATP7A; Iron deficiency results in increased expression of more ... CTD PMID:16629162|PMID:21852364|PMID:23174565|PMID:23814049|PMID:24089420|PMID:24174620 Atp7a Rat iron(0) affects metabolic processing ISO RGD:10215 6480464 ATP7A protein mutant form affects the metabolism of Iron CTD PMID:25247420 Atp7a Rat iron(0) multiple interactions ISO RGD:10215 6480464 [ATP7A gene mutant form co-treated with Iron deficiency] results in increased uptake of Copper; [ATP7A more ... CTD PMID:23776592 Atp7a Rat iron(0) affects transport EXP 6480464 ATP7A mutant form affects the transport of Iron CTD PMID:24174620 Atp7a Rat iron(0) decreases oxidation ISO RGD:10215 6480464 ATP7A gene mutant form results in decreased oxidation of Iron CTD PMID:23776592 Atp7a Rat iron(0) multiple interactions EXP 6480464 [Iron deficiency results in increased expression of ATP7A] which results in increased abundance of Copper CTD PMID:24174620 Atp7a Rat iron(0) increases expression ISO RGD:10215 6480464 Iron deficiency results in increased expression of ATP7A mRNA CTD PMID:23776592|PMID:24089420 Atp7a Rat iron(0) increases response to substance ISO RGD:10215 6480464 ATP7A gene mutant form results in increased susceptibility to Iron deficiency CTD PMID:23776592 Atp7a Rat ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of ATP7A mRNA CTD PMID:20080153 Atp7a Rat L-1,4-dithiothreitol multiple interactions ISO RGD:10216 6480464 Dithiothreitol inhibits the reaction [Ethylmaleimide results in increased glutathionylation of ATP7A protein] CTD PMID:20566629 Atp7a Rat lead diacetate multiple interactions EXP 6480464 ATP7A protein modified form inhibits the reaction [lead acetate binds to HSPA5 protein] CTD PMID:10702365 Atp7a Rat lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of ATP7A mRNA; lead acetate results in decreased expression more ... CTD PMID:24316150 Atp7a Rat lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of ATP7A mRNA CTD PMID:25579025 Atp7a Rat lipopolysaccharide increases expression ISO RGD:10215 6480464 Lipopolysaccharides results in increased expression of ATP7A mRNA CTD PMID:22369063 Atp7a Rat manganese atom affects localization EXP 6480464 Manganese affects the localization of ATP7A protein CTD PMID:24614235 Atp7a Rat manganese atom decreases expression EXP 6480464 Manganese results in decreased expression of ATP7A mRNA; Manganese results in decreased expression of ATP7A more ... CTD PMID:24614235 Atp7a Rat manganese(0) affects localization EXP 6480464 Manganese affects the localization of ATP7A protein CTD PMID:24614235 Atp7a Rat manganese(0) decreases expression EXP 6480464 Manganese results in decreased expression of ATP7A mRNA; Manganese results in decreased expression of ATP7A more ... CTD PMID:24614235 Atp7a Rat manganese(II) chloride affects localization EXP 6480464 manganese chloride affects the localization of ATP7A protein CTD PMID:24614235 Atp7a Rat manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of ATP7A mRNA; manganese chloride results in decreased expression more ... CTD PMID:24614235 Atp7a Rat melanins multiple interactions ISO RGD:10216 6480464 [TYR protein co-treated with ATP7A protein] results in increased abundance of Melanins CTD PMID:11092760 Atp7a Rat methapyrilene affects methylation ISO RGD:10216 6480464 Methapyrilene affects the methylation of ATP7A intron CTD PMID:30157460 Atp7a Rat methimazole increases expression EXP 6480464 Methimazole results in increased expression of ATP7A mRNA CTD PMID:22504374 Atp7a Rat methyl methanesulfonate increases expression ISO RGD:10216 6480464 Methyl Methanesulfonate results in increased expression of ATP7A mRNA CTD PMID:23649840 Atp7a Rat methylmercury chloride decreases expression ISO RGD:10216 6480464 methylmercuric chloride results in decreased expression of ATP7A mRNA CTD PMID:28001369 Atp7a Rat mithramycin multiple interactions EXP 6480464 Plicamycin inhibits the reaction [cobaltous chloride results in increased expression of ATP7A mRNA] CTD PMID:23814049 Atp7a Rat mithramycin decreases expression EXP 6480464 Plicamycin results in decreased expression of ATP7A mRNA CTD PMID:23814049 Atp7a Rat mitoxantrone decreases response to substance ISO RGD:10216 6480464 ATP7A protein results in decreased susceptibility to Mitoxantrone CTD PMID:17510416 Atp7a Rat monensin A multiple interactions ISO RGD:10216 6480464 Monensin inhibits the reaction [ATP7A protein affects the localization of Doxorubicin] CTD PMID:17510416 Atp7a Rat N-ethylmaleimide increases glutathionylation ISO RGD:10216 6480464 Ethylmaleimide results in increased glutathionylation of ATP7A protein CTD PMID:20566629 Atp7a Rat N-ethylmaleimide multiple interactions ISO RGD:10216 6480464 Dithiothreitol inhibits the reaction [Ethylmaleimide results in increased glutathionylation of ATP7A protein] CTD PMID:20566629 Atp7a Rat neocuproine multiple interactions ISO RGD:10215 6480464 neocuproine inhibits the reaction [ATP7A protein mutant form promotes the reaction [lipopolysaccharide, E coli O55-B5 more ... CTD PMID:23604539 Atp7a Rat nitrofen decreases expression EXP 6480464 nitrofen results in decreased expression of ATP7A mRNA; nitrofen results in decreased expression of ATP7A more ... CTD PMID:25319798 Atp7a Rat omeprazole multiple interactions ISO RGD:10216 6480464 Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein] CTD PMID:25337692 Atp7a Rat omeprazole multiple interactions ISO RGD:10215 6480464 Omeprazole inhibits the reaction [Copper affects the localization of ATP7A protein]; Omeprazole inhibits the reaction more ... CTD PMID:25337692 Atp7a Rat oxaliplatin multiple interactions ISO RGD:10216 6480464 [MIR495 mRNA results in decreased expression of ATP7A protein] which results in increased susceptibility to more ... CTD PMID:24038379 Atp7a Rat oxaliplatin decreases response to substance ISO RGD:10216 6480464 ATP7A protein results in decreased susceptibility to oxaliplatin CTD PMID:25801007 Atp7a Rat oxaliplatin affects response to substance ISO RGD:10216 6480464 ATP7A protein affects the susceptibility to oxaliplatin CTD PMID:16773204|PMID:17609664 Atp7a Rat oxaliplatin increases expression ISO RGD:10216 6480464 oxaliplatin results in increased expression of ATP7A mRNA CTD PMID:16773204 Atp7a Rat paclitaxel decreases response to substance ISO RGD:10216 6480464 ATP7A protein results in decreased susceptibility to Paclitaxel CTD PMID:17510416 Atp7a Rat paclitaxel increases expression ISO RGD:10216 6480464 Paclitaxel results in increased expression of ATP7A mRNA CTD PMID:20737486 Atp7a Rat paracetamol affects expression ISO RGD:10215 6480464 Acetaminophen affects the expression of ATP7A mRNA CTD PMID:17562736 Atp7a Rat paraquat multiple interactions ISO RGD:10216 6480464 ATP7A protein promotes the reaction [Paraquat results in increased chemical synthesis of Hydrogen Peroxide] CTD PMID:29058724 Atp7a Rat paraquat increases expression ISO RGD:10216 6480464 Paraquat results in increased expression of ATP7A mRNA CTD PMID:34097952 Atp7a Rat paraquat increases response to substance ISO RGD:10216 6480464 ATP7A protein results in increased susceptibility to Paraquat CTD PMID:29058724 Atp7a Rat phorbol 13-acetate 12-myristate increases expression ISO RGD:10216 6480464 Tetradecanoylphorbol Acetate results in increased expression of ATP7A protein CTD PMID:19205902 Atp7a Rat phorbol 13-acetate 12-myristate multiple interactions ISO RGD:10216 6480464 [Tetradecanoylphorbol Acetate results in increased expression of ATP7A protein] which results in increased export of more ... CTD PMID:19205902 Atp7a Rat pirinixic acid multiple interactions ISO RGD:10215 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... CTD PMID:19710929 Atp7a Rat pirinixic acid decreases expression ISO RGD:10215 6480464 pirinixic acid results in decreased expression of ATP7A mRNA CTD PMID:20813756 Atp7a Rat platinum increases uptake ISO RGD:10215 6480464 ATP7A protein results in increased uptake of Platinum CTD PMID:16170571 Atp7a Rat platinum(0) increases uptake ISO RGD:10215 6480464 ATP7A protein results in increased uptake of Platinum CTD PMID:16170571 Atp7a Rat potassium chromate decreases expression ISO RGD:10216 6480464 potassium chromate(VI) results in decreased expression of ATP7A mRNA CTD PMID:22714537 Atp7a Rat pyrrolidine dithiocarbamate decreases expression ISO RGD:10216 6480464 pyrrolidine dithiocarbamic acid results in decreased expression of ATP7A CTD PMID:25070243 Atp7a Rat quercetin decreases expression ISO RGD:10216 6480464 Quercetin results in decreased expression of ATP7A mRNA CTD PMID:21632981 Atp7a Rat rac-lactic acid decreases expression ISO RGD:10216 6480464 Lactic Acid results in decreased expression of ATP7A mRNA CTD PMID:30851411 Atp7a Rat resveratrol multiple interactions ISO RGD:10216 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of ATP7A mRNA CTD PMID:23557933 Atp7a Rat satraplatin decreases response to substance ISO RGD:10215 6480464 ATP7A protein results in decreased susceptibility to satraplatin metabolite CTD PMID:16170571 Atp7a Rat SB 431542 multiple interactions ISO RGD:10216 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... CTD PMID:27188386 Atp7a Rat silicon dioxide decreases expression ISO RGD:10216 6480464 Silicon Dioxide analog results in decreased expression of ATP7A mRNA CTD PMID:25895662 Atp7a Rat silicon dioxide increases expression ISO RGD:10215 6480464 Silicon Dioxide results in increased expression of ATP7A mRNA CTD PMID:38403151 Atp7a Rat silver atom affects localization ISO RGD:10215 6480464 Silver affects the localization of ATP7A protein CTD PMID:16317117 Atp7a Rat silver atom decreases expression ISO RGD:10215 6480464 Silver results in decreased expression of ATP7A mRNA CTD PMID:27131904 Atp7a Rat silver atom affects binding ISO RGD:10216 6480464 Silver binds to ATP7A protein CTD PMID:10841766|PMID:21646353 Atp7a Rat silver monochloride affects localization ISO RGD:10215 6480464 silver chloride affects the localization of ATP7A protein CTD PMID:16317117 Atp7a Rat silver(0) affects localization ISO RGD:10215 6480464 Silver affects the localization of ATP7A protein CTD PMID:16317117 Atp7a Rat silver(0) decreases expression ISO RGD:10215 6480464 Silver results in decreased expression of ATP7A mRNA CTD PMID:27131904 Atp7a Rat silver(0) affects binding ISO RGD:10216 6480464 Silver binds to ATP7A protein CTD PMID:10841766|PMID:21646353 Atp7a Rat sodium arsenate increases expression ISO RGD:10215 6480464 sodium arsenate results in increased expression of ATP7A mRNA CTD PMID:21795629 Atp7a Rat sodium arsenite increases expression ISO RGD:10216 6480464 sodium arsenite results in increased expression of ATP7A mRNA CTD PMID:38568856 Atp7a Rat sodium arsenite decreases expression ISO RGD:10215 6480464 sodium arsenite results in decreased expression of ATP7A mRNA CTD PMID:37682722 Atp7a Rat streptozocin multiple interactions ISO RGD:10215 6480464 ATP7A gene mutant form promotes the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; more ... CTD PMID:23884884 Atp7a Rat streptozocin decreases expression ISO RGD:10215 6480464 Streptozocin results in decreased expression of ATP7A protein CTD PMID:23884884 Atp7a Rat succimer multiple interactions ISO RGD:10215 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of ATP7A mRNA CTD PMID:26378955 Atp7a Rat superoxide increases abundance ISO RGD:10215 6480464 ATP7A mutant form results in increased abundance of Superoxides CTD PMID:18768397 Atp7a Rat superoxide multiple interactions ISO RGD:10215 6480464 [ATP7A protein results in increased activity of SOD3 protein] which results in decreased chemical synthesis more ... CTD PMID:18768397|PMID:23884884 Atp7a Rat tetrachloromethane increases expression ISO RGD:10215 6480464 Carbon Tetrachloride results in increased expression of ATP7A mRNA CTD PMID:27339419 Atp7a Rat tetrathiomolybdate(2-) multiple interactions ISO RGD:10215 6480464 tetrathiomolybdate inhibits the reaction [Oxygen deficiency affects the localization of ATP7A protein] CTD PMID:19351718 Atp7a Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of ATP7A mRNA CTD PMID:23411599 Atp7a Rat titanium dioxide decreases expression ISO RGD:10215 6480464 titanium dioxide results in decreased expression of ATP7A mRNA CTD PMID:29264374 Atp7a Rat titanium dioxide multiple interactions ISO RGD:10215 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ATP7A more ... CTD PMID:29950665 Atp7a Rat trichostatin A increases expression ISO RGD:10216 6480464 trichostatin A results in increased expression of ATP7A mRNA CTD PMID:28542535 Atp7a Rat troglitazone decreases expression ISO RGD:10215 6480464 troglitazone results in decreased expression of ATP7A mRNA CTD PMID:28973697 Atp7a Rat tungsten increases expression ISO RGD:10215 6480464 Tungsten results in increased expression of ATP7A mRNA CTD PMID:30912803 Atp7a Rat valproic acid increases expression ISO RGD:10216 6480464 Valproic Acid results in increased expression of ATP7A mRNA CTD PMID:19101580|PMID:29154799 Atp7a Rat valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of ATP7A mRNA CTD PMID:29427782 Atp7a Rat valproic acid decreases expression ISO RGD:10215 6480464 Valproic Acid results in decreased expression of ATP7A mRNA CTD PMID:20546886 Atp7a Rat valproic acid increases methylation ISO RGD:10216 6480464 Valproic Acid results in increased methylation of ATP7A gene CTD PMID:29154799 Atp7a Rat vincristine decreases response to substance ISO RGD:10216 6480464 ATP7A protein results in decreased susceptibility to Vincristine CTD PMID:17510416