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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2179
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atp7a
Name: ATPase copper transporting alpha
Acc ID: CHEBI:44485
Term: N-ethylmaleimide
Definition: A member of the class of maleimides that is the N-ethyl derivative of maleimide.
Chemical ID: MESH:D005033
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atp7aincreases glutathionylationISORGD:102166480464CTDEthylmaleimide results in increased glutathionylation of ATP7A protein

PMID:20566629
Atp7amultiple interactionsISORGD:102166480464CTDDithiothreitol inhibits the reaction [Ethylmaleimide results in increased glutathionylation of ATP7A protein]

PMID:20566629
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