The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
[picropodophyllin results in decreased activity of IGF1R protein] inhibits the reaction [Cadmium Chloride results in decreased activity of FOXO3 protein]; [picropodophyllin results in decreased activity of IGF1R protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of FOXO3 protein]
[picropodophyllin co-treated with IGF1 protein] results in increased expression of TNF mRNA; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of IL1B mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of IL6 mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of TLR4 mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of TNF mRNA]; picropodophyllin inhibits the reaction [IGF1 protein results in decreased expression of TLR4 mRNA]; picropodophyllin inhibits the reaction [IGF1 protein results in increased expression of IL1B mRNA]; picropodophyllin promotes the reaction [IGF1 protein results in increased expression of IL6 mRNA]
picropodophyllin results in decreased activity of IGF1R protein [picropodophyllin results in decreased activity of IGF1R protein] inhibits the reaction [Cadmium Chloride results in decreased activity of FOXO3 protein]; [picropodophyllin results in decreased activity of IGF1R protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of FOXO3 protein] picropodophyllin binds to and results in decreased activity of IGF1R protein
[picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of IL1B mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA; picropodophyllin inhibits the reaction [IGF1 protein results in increased expression of IL1B mRNA]
[picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of IL6 mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] results in increased expression of IL6 mRNA; picropodophyllin promotes the reaction [IGF1 protein results in increased expression of IL6 mRNA] picropodophyllin results in increased expression of IL6 mRNA
picropodophyllin inhibits the reaction [[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Hexachlorobenzene] results in increased activity of MMP2 protein]
[picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of TLR4 mRNA]; picropodophyllin inhibits the reaction [IGF1 protein results in decreased expression of TLR4 mRNA]
[picropodophyllin co-treated with IGF1 protein] results in increased expression of TNF mRNA; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of TNF mRNA]