Ahi1 (Abelson helper integration site 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ahi1 (Abelson helper integration site 1) Rattus norvegicus
Analyze
Symbol: Ahi1
Name: Abelson helper integration site 1
RGD ID: 1303040
Description: Predicted to have identical protein binding activity. Involved in several processes, including embryonic brain development; negative regulation of glucose import; and response to food. Localizes to cytoplasm. Human ortholog(s) of this gene implicated in Joubert syndrome 3; Joubert syndrome 4; and autism spectrum disorder. Orthologous to human AHI1 (Abelson helper integration site 1); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; 3,3',5,5'-tetrabromobisphenol A; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: abelson helper integration site 1 protein homolog; Ahi-1; jouberin; jouberin-like; LOC103690149
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2115,768,047 - 15,886,744 (+)NCBI
Rnor_6.0 Ensembl116,478,127 - 16,601,769 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0116,478,127 - 16,601,769 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0118,952,969 - 19,086,123 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0119,111,106 - 19,149,884 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4116,332,801 - 16,454,055 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1116,332,862 - 16,454,114 (+)NCBI
Celera114,188,321 - 14,307,100 (+)NCBICelera
Cytogenetic Map1p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular protein localization  (ISO,ISS)
central nervous system development  (ISO,ISS)
cilium assembly  (ISO,ISS)
cloaca development  (ISO,ISS)
embryonic brain development  (IEP)
eye photoreceptor cell development  (ISO)
heart looping  (ISO,ISS)
hindbrain development  (ISO,ISS)
Kupffer's vesicle development  (ISS)
left/right axis specification  (ISS)
morphogenesis of a polarized epithelium  (ISO,ISS)
negative regulation of apoptotic process  (ISO,ISS)
negative regulation of glucose import  (IMP)
non-motile cilium assembly  (ISO)
otic vesicle development  (ISO,ISS)
photoreceptor cell outer segment organization  (ISO,ISS)
positive regulation of gene expression  (ISO)
positive regulation of growth  (ISO)
positive regulation of neuron projection development  (ISO)
positive regulation of polarized epithelial cell differentiation  (ISO,ISS)
positive regulation of receptor internalization  (ISO,ISS)
positive regulation of transcription by RNA polymerase II  (ISO,ISS)
pronephric duct morphogenesis  (ISS)
pronephric nephron tubule morphogenesis  (ISO,ISS)
protein localization to organelle  (ISO)
regulation of behavior  (ISO,ISS)
regulation of protein secretion  (ISO)
response to food  (IEP)
retina development in camera-type eye  (ISO)
retina layer formation  (ISO,ISS)
retinal cone cell development  (ISO)
retinal rod cell development  (ISO)
specification of axis polarity  (ISO,ISS)
spinal cord development  (IEP)
transmembrane receptor protein tyrosine kinase signaling pathway  (ISO,ISS)
vesicle targeting  (ISO)
vesicle-mediated transport  (ISO,ISS)

Cellular Component

Molecular Function

References

References - curated
1. Alvarez Retuerto AI, etal., Hum Mol Genet. 2008 Dec 15;17(24):3887-96. doi: 10.1093/hmg/ddn291. Epub 2008 Sep 9.
2. Chafai-Elalaoui S, etal., J Med Case Rep. 2015 Nov 5;9:254. doi: 10.1186/s13256-015-0732-3.
3. Dixon-Salazar T, etal., Am J Hum Genet 2004 Dec;75(6):979-87. Epub 2004 Oct 04.
4. Ferland RJ, etal., Nat Genet. 2004 Sep;36(9):1008-13. Epub 2004 Aug 22.
5. Han SB, etal., Biochem Biophys Res Commun. 2009 Dec 18;390(3):535-40. doi: 10.1016/j.bbrc.2009.09.133. Epub 2009 Oct 9.
6. Kroes HY, etal., Eur J Med Genet. 2008 Jan-Feb;51(1):24-34. Epub 2007 Oct 6.
7. Lancaster MA, etal., Nat Med. 2011 Jun;17(6):726-31. doi: 10.1038/nm.2380. Epub 2011 May 29.
8. MGD data from the GO Consortium
9. OMIM Disease Annotation Pipeline
10. Parisi MA, etal., J Med Genet. 2006 Apr;43(4):334-9. Epub 2005 Sep 9.
11. Prior MJ, etal., Metabolism. 2010 Jul;59(7):1057-64. doi: 10.1016/j.metabol.2009.11.002. Epub 2009 Dec 31.
12. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. RGD automated import pipeline for gene-chemical interactions
14. RGD comprehensive gene curation
15. Tory K, etal., J Am Soc Nephrol. 2007 May;18(5):1566-75. Epub 2007 Apr 4.
16. Valente EM, etal., Ann Neurol. 2006 Mar;59(3):527-34.
17. Weng L, etal., J Neurosci. 2013 May 8;33(19):8172-84. doi: 10.1523/JNEUROSCI.0119-13.2013.
18. Zaki MS, etal., Neurology. 2008 Feb 12;70(7):556-65. doi: 10.1212/01.wnl.0000277644.12087.fd.
Additional References at PubMed
PMID:12186888   PMID:18633336   PMID:18636121   PMID:18936234   PMID:19625297   PMID:19718039   PMID:20081859   PMID:20592197   PMID:20956301   PMID:21959375   PMID:22179047   PMID:23532844  
PMID:29899041  


Genomics

Comparative Map Data
Ahi1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2115,768,047 - 15,886,744 (+)NCBI
Rnor_6.0 Ensembl116,478,127 - 16,601,769 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0116,478,127 - 16,601,769 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0118,952,969 - 19,086,123 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0119,111,106 - 19,149,884 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4116,332,801 - 16,454,055 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1116,332,862 - 16,454,114 (+)NCBI
Celera114,188,321 - 14,307,100 (+)NCBICelera
Cytogenetic Map1p12NCBI
AHI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6135,283,407 - 135,498,434 (-)EnsemblGRCh38hg38GRCh38
GRCh386135,283,532 - 135,497,771 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376135,604,670 - 135,818,878 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366135,646,817 - 135,860,576 (-)NCBINCBI36hg18NCBI36
Build 346135,646,817 - 135,860,576NCBI
Celera6136,345,472 - 136,559,269 (-)NCBI
Cytogenetic Map6q23.3NCBI
HuRef6133,169,009 - 133,382,975 (-)NCBIHuRef
CHM1_16135,867,357 - 136,081,325 (-)NCBICHM1_1
Ahi1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391020,827,274 - 20,956,328 (+)NCBIGRCm39mm39
GRCm39 Ensembl1020,828,446 - 20,956,328 (+)Ensembl
GRCm381020,952,232 - 21,080,429 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1020,952,547 - 21,080,429 (+)EnsemblGRCm38mm10GRCm38
MGSCv371020,672,391 - 20,800,235 (+)NCBIGRCm37mm9NCBIm37
MGSCv361020,642,080 - 20,769,845 (+)NCBImm8
Celera1020,846,024 - 20,981,336 (+)NCBICelera
Cytogenetic Map10A3NCBI
cM Map109.75NCBI
Ahi1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554391,276,760 - 1,474,202 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554391,277,185 - 1,460,296 (+)NCBIChiLan1.0ChiLan1.0
AHI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16137,149,457 - 137,366,731 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6137,156,237 - 137,361,232 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06133,055,026 - 133,273,591 (-)NCBIMhudiblu_PPA_v0panPan3
AHI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1127,966,101 - 28,199,163 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl127,998,874 - 28,198,351 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha128,845,716 - 29,079,414 (-)NCBI
ROS_Cfam_1.0128,122,122 - 28,354,873 (-)NCBI
UMICH_Zoey_3.1128,008,276 - 28,240,745 (-)NCBI
UNSW_CanFamBas_1.0127,888,338 - 28,120,623 (-)NCBI
UU_Cfam_GSD_1.0128,198,308 - 28,432,026 (-)NCBI
Ahi1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946123,101,413 - 123,278,028 (-)NCBI
SpeTri2.0NW_0049365602,881,631 - 3,057,256 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AHI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl128,566,266 - 28,760,468 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1128,566,279 - 28,760,471 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2132,048,945 - 32,243,734 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AHI1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11337,918,902 - 38,138,838 (+)NCBI
ChlSab1.1 Ensembl1337,924,440 - 38,139,366 (+)Ensembl
Vero_WHO_p1.0NW_02366604010,124,102 - 10,342,579 (+)NCBI
Ahi1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248862,189,753 - 2,403,174 (+)NCBI

Position Markers
D1Rat148  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,760,582 - 15,760,793 (+)MAPPER
Rnor_6.0116,470,664 - 16,470,874NCBIRnor6.0
Rnor_5.0118,951,160 - 18,951,370UniSTSRnor5.0
RGSC_v3.4116,325,338 - 16,325,548UniSTSRGSC3.4
RGSC_v3.4116,325,337 - 16,325,548RGDRGSC3.4
RGSC_v3.1116,325,400 - 16,325,610RGD
Celera114,180,858 - 14,181,068UniSTS
RH 3.4 Map1165.0RGD
RH 3.4 Map1165.0UniSTS
RH 2.0 Map186.6RGD
SHRSP x BN Map112.5699RGD
FHH x ACI Map114.85RGD
Cytogenetic Map1p12UniSTS
RH131918  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,891,833 - 15,892,037 (+)MAPPER
Rnor_6.0117,630,287 - 17,630,490NCBIRnor6.0
Rnor_6.0116,607,096 - 16,607,299NCBIRnor6.0
Rnor_5.0119,154,974 - 19,155,177UniSTSRnor5.0
Rnor_5.0119,085,724 - 19,085,927UniSTSRnor5.0
RGSC_v3.4116,459,142 - 16,459,345UniSTSRGSC3.4
Celera114,312,190 - 14,312,393UniSTS
RH 3.4 Map1148.81UniSTS
Cytogenetic Map1p12UniSTS
RH143155  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,890,892 - 15,891,036 (+)MAPPER
Rnor_6.0117,629,346 - 17,629,489NCBIRnor6.0
Rnor_6.0116,606,155 - 16,606,298NCBIRnor6.0
Rnor_5.0119,154,033 - 19,154,176UniSTSRnor5.0
Rnor_5.0119,084,783 - 19,084,926UniSTSRnor5.0
RGSC_v3.4116,458,201 - 16,458,344UniSTSRGSC3.4
Celera114,311,249 - 14,311,392UniSTS
RH 3.4 Map1164.8UniSTS
Cytogenetic Map1p12UniSTS
AW531129  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,842,604 - 15,842,780 (+)MAPPER
Rnor_6.0116,557,631 - 16,557,806NCBIRnor6.0
Rnor_5.0119,036,259 - 19,036,434UniSTSRnor5.0
RGSC_v3.4116,410,059 - 16,410,234UniSTSRGSC3.4
Celera114,263,104 - 14,263,279UniSTS
RH 3.4 Map1165.12UniSTS
Cytogenetic Map1p12UniSTS
BE121279  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,879,013 - 15,879,217 (+)MAPPER
Rnor_6.0117,617,467 - 17,617,670NCBIRnor6.0
Rnor_6.0116,594,039 - 16,594,242NCBIRnor6.0
Rnor_5.0119,142,154 - 19,142,357UniSTSRnor5.0
Rnor_5.0119,072,667 - 19,072,870UniSTSRnor5.0
RGSC_v3.4116,446,322 - 16,446,525UniSTSRGSC3.4
Celera114,299,370 - 14,299,573UniSTS
RH 3.4 Map1165.41UniSTS
Cytogenetic Map1p12UniSTS
RH137467  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,882,699 - 15,882,883 (+)MAPPER
Rnor_6.0117,621,153 - 17,621,336NCBIRnor6.0
Rnor_6.0116,597,725 - 16,597,908NCBIRnor6.0
Rnor_5.0119,076,353 - 19,076,536UniSTSRnor5.0
Rnor_5.0119,145,840 - 19,146,023UniSTSRnor5.0
RGSC_v3.4116,450,008 - 16,450,191UniSTSRGSC3.4
Celera114,303,056 - 14,303,239UniSTS
Cytogenetic Map1p12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1124368159Rat
2298546Neuinf4Neuroinflammation QTL 45.1nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1128468970Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1134993530Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1134993530Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)1134993530Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1164407321Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)125439343579402Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)125439343579402Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)125439343579402Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)125439386904217Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1186804543724576Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1457869349578693Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15655769122614963Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1565577285706974Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11131448975844121Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)11131448983657083Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11131448983657083Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11131448983657083Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11131448983657083Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11131448983657083Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11131448983657083Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11131448983657083Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)11131465834993348Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11249343957493439Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11362925158629251Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)11603307820130904Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11614314349547474Rat
5684999Bss102Bone structure and strength QTL 1025.50.00000072tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11614314349547474Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:79
Count of miRNA genes:65
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000019076
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 10 20 4 16 4 74 31 41 10
Low 3 33 37 37 3 37 8 11 4 1 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000019076   ⟹   ENSRNOP00000019077
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl116,478,127 - 16,601,769 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000075461   ⟹   ENSRNOP00000067868
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl117,602,281 - 17,625,197 (+)Ensembl
RefSeq Acc Id: NM_001002277   ⟹   NP_001002277
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2115,768,047 - 15,886,744 (+)NCBI
Rnor_6.0116,478,127 - 16,601,769 (+)NCBI
Rnor_5.0119,111,106 - 19,149,884 (+)NCBI
RGSC_v3.4116,332,801 - 16,454,055 (+)RGD
Celera114,188,321 - 14,307,100 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001002277 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAM94632 (Get FASTA)   NCBI Sequence Viewer  
  AAT66919 (Get FASTA)   NCBI Sequence Viewer  
  Q6DTM3 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001002277   ⟸   NM_001002277
- Sequence:
RefSeq Acc Id: ENSRNOP00000019077   ⟸   ENSRNOT00000019076
RefSeq Acc Id: ENSRNOP00000067868   ⟸   ENSRNOT00000075461
Protein Domains
SH3   WD_REPEATS_REGION

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303040 AgrOrtholog
Ensembl Genes ENSRNOG00000013969 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000046617 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000019077 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000067868 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019076 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000075461 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AHI1_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:308923 UniProtKB/Swiss-Prot
NCBI Gene 308923 ENTREZGENE
Pfam SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ahi1 PhenoGen
PRINTS SH3DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt AHI1_RAT UniProtKB/Swiss-Prot
  F1M9F9_RAT UniProtKB/TrEMBL
  M0RE04_RAT UniProtKB/TrEMBL
  Q6DTM3 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Ahi1  Abelson helper integration site 1  LOC103690149  jouberin-like  Data Merged 737654 PROVISIONAL
2014-08-25 LOC103690149  jouberin-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-02-14 Ahi1  Abelson helper integration site 1      Symbol and Name status set to provisional 70820 PROVISIONAL