Ahi1 (Abelson helper integration site 1) - Rat Genome Database

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Gene: Ahi1 (Abelson helper integration site 1) Rattus norvegicus
Analyze
Symbol: Ahi1
Name: Abelson helper integration site 1
RGD ID: 1303040
Description: Predicted to enable identical protein binding activity. Involved in several processes, including embryonic brain development; negative regulation of glucose import; and response to food. Predicted to be located in adherens junction; microtubule organizing center; and photoreceptor cell cilium. Predicted to be part of MKS complex. Predicted to be active in ciliary basal body. Human ortholog(s) of this gene implicated in Joubert syndrome 3; Joubert syndrome 4; and autism spectrum disorder. Orthologous to human AHI1 (Abelson helper integration site 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: abelson helper integration site 1 protein homolog; Ahi-1; jouberin; jouberin-like; LOC103690149
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8117,580,859 - 17,711,775 (+)NCBIGRCr8
mRatBN7.2115,762,485 - 15,891,213 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl115,762,462 - 15,891,041 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx115,516,117 - 15,645,446 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0121,518,001 - 21,647,337 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0115,742,325 - 15,871,051 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0116,478,127 - 16,601,769 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl116,478,127 - 16,601,769 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0118,952,969 - 19,086,123 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0119,111,106 - 19,149,884 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4116,332,801 - 16,454,055 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1116,332,862 - 16,454,114 (+)NCBI
Celera114,188,321 - 14,307,100 (+)NCBICelera
Cytogenetic Map1p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Association of common variants in the Joubert syndrome gene (AHI1) with autism. Alvarez Retuerto AI, etal., Hum Mol Genet. 2008 Dec 15;17(24):3887-96. doi: 10.1093/hmg/ddn291. Epub 2008 Sep 9.
2. A homozygous AHI1 gene mutation (p.Thr304AsnfsX6) in a consanguineous Moroccan family with Joubert syndrome: a case report. Chafai-Elalaoui S, etal., J Med Case Rep. 2015 Nov 5;9:254. doi: 10.1186/s13256-015-0732-3.
3. Mutations in the AHI1 gene, encoding jouberin, cause Joubert syndrome with cortical polymicrogyria. Dixon-Salazar T, etal., Am J Hum Genet 2004 Dec;75(6):979-87. Epub 2004 Oct 04.
4. Abnormal cerebellar development and axonal decussation due to mutations in AHI1 in Joubert syndrome. Ferland RJ, etal., Nat Genet. 2004 Sep;36(9):1008-13. Epub 2004 Aug 22.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Regulation of AHI1 expression in adult rat brain: Implication in hypothalamic feeding control. Han SB, etal., Biochem Biophys Res Commun. 2009 Dec 18;390(3):535-40. doi: 10.1016/j.bbrc.2009.09.133. Epub 2009 Oct 9.
7. DNA analysis of AHI1, NPHP1 and CYCLIN D1 in Joubert syndrome patients from the Netherlands. Kroes HY, etal., Eur J Med Genet. 2008 Jan-Feb;51(1):24-34. Epub 2007 Oct 6.
8. Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome. Lancaster MA, etal., Nat Med. 2011 Jun;17(6):726-31. doi: 10.1038/nm.2380. Epub 2011 May 29.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. AHI1 mutations cause both retinal dystrophy and renal cystic disease in Joubert syndrome. Parisi MA, etal., J Med Genet. 2006 Apr;43(4):334-9. Epub 2005 Sep 9.
12. The characterization of Abelson helper integration site-1 in skeletal muscle and its links to the metabolic syndrome. Prior MJ, etal., Metabolism. 2010 Jul;59(7):1057-64. doi: 10.1016/j.metabol.2009.11.002. Epub 2009 Dec 31.
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. High NPHP1 and NPHP6 mutation rate in patients with Joubert syndrome and nephronophthisis: potential epistatic effect of NPHP6 and AHI1 mutations in patients with NPHP1 mutations. Tory K, etal., J Am Soc Nephrol. 2007 May;18(5):1566-75. Epub 2007 Apr 4.
17. AHI1 gene mutations cause specific forms of Joubert syndrome-related disorders. Valente EM, etal., Ann Neurol. 2006 Mar;59(3):527-34.
18. Loss of Ahi1 affects early development by impairing BM88/Cend1-mediated neuronal differentiation. Weng L, etal., J Neurosci. 2013 May 8;33(19):8172-84. doi: 10.1523/JNEUROSCI.0119-13.2013.
19. The molar tooth sign: a new Joubert syndrome and related cerebellar disorders classification system tested in Egyptian families. Zaki MS, etal., Neurology. 2008 Feb 12;70(7):556-65. doi: 10.1212/01.wnl.0000277644.12087.fd.
Additional References at PubMed
PMID:12186888   PMID:18633336   PMID:18636121   PMID:18936234   PMID:19625297   PMID:19718039   PMID:20081859   PMID:20592197   PMID:20956301   PMID:21959375   PMID:22179047   PMID:23532844  
PMID:29899041  


Genomics

Comparative Map Data
Ahi1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8117,580,859 - 17,711,775 (+)NCBIGRCr8
mRatBN7.2115,762,485 - 15,891,213 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl115,762,462 - 15,891,041 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx115,516,117 - 15,645,446 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0121,518,001 - 21,647,337 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0115,742,325 - 15,871,051 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0116,478,127 - 16,601,769 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl116,478,127 - 16,601,769 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0118,952,969 - 19,086,123 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0119,111,106 - 19,149,884 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4116,332,801 - 16,454,055 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1116,332,862 - 16,454,114 (+)NCBI
Celera114,188,321 - 14,307,100 (+)NCBICelera
Cytogenetic Map1p12NCBI
AHI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386135,283,532 - 135,497,740 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6135,283,407 - 135,498,434 (-)EnsemblGRCh38hg38GRCh38
GRCh376135,604,670 - 135,818,878 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366135,646,817 - 135,860,576 (-)NCBINCBI36Build 36hg18NCBI36
Build 346135,646,817 - 135,860,576NCBI
Celera6136,345,472 - 136,559,269 (-)NCBICelera
Cytogenetic Map6q23.3NCBI
HuRef6133,169,009 - 133,382,975 (-)NCBIHuRef
CHM1_16135,867,357 - 136,081,325 (-)NCBICHM1_1
T2T-CHM13v2.06136,471,820 - 136,685,994 (-)NCBIT2T-CHM13v2.0
Ahi1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391020,827,274 - 20,956,328 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1020,828,446 - 20,956,328 (+)EnsemblGRCm39 Ensembl
GRCm381020,952,232 - 21,080,429 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1020,952,547 - 21,080,429 (+)EnsemblGRCm38mm10GRCm38
MGSCv371020,672,391 - 20,800,235 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361020,642,080 - 20,769,845 (+)NCBIMGSCv36mm8
Celera1020,846,024 - 20,981,336 (+)NCBICelera
Cytogenetic Map10A3NCBI
cM Map1016.0NCBI
Ahi1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554391,276,760 - 1,474,202 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554391,277,185 - 1,460,296 (+)NCBIChiLan1.0ChiLan1.0
AHI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25155,261,308 - 155,484,081 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16153,166,815 - 153,379,460 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06133,055,026 - 133,273,591 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16137,149,457 - 137,366,731 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6137,156,237 - 137,361,232 (-)Ensemblpanpan1.1panPan2
AHI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1127,966,101 - 28,199,163 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl127,998,874 - 28,198,351 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha128,845,716 - 29,079,414 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0128,122,122 - 28,354,873 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl128,154,194 - 28,354,314 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1128,008,276 - 28,240,745 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0127,888,338 - 28,120,623 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0128,198,308 - 28,432,026 (-)NCBIUU_Cfam_GSD_1.0
Ahi1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946123,101,413 - 123,278,028 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365602,881,977 - 3,038,725 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365602,881,631 - 3,057,256 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AHI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl128,566,266 - 28,760,468 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1128,566,279 - 28,760,471 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2132,048,945 - 32,243,734 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AHI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11337,918,902 - 38,138,838 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1337,924,440 - 38,139,366 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604010,124,102 - 10,342,579 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ahi1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248862,189,655 - 2,397,364 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248862,189,753 - 2,403,174 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ahi1
333 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:79
Count of miRNA genes:65
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000019076
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)150910843284926Rat
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1124744506Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1132356093Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11543162149361612Rat
2298546Neuinf4Neuroinflammation QTL 45.1nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1128736750Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11543162149361612Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)11148148232355910Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1132356093Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1592587724697545Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)11532110019121980Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1224439043433040Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1132356093Rat

Markers in Region
D1Rat148  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,760,582 - 15,760,793 (+)MAPPERmRatBN7.2
Rnor_6.0116,470,664 - 16,470,874NCBIRnor6.0
Rnor_5.0118,951,160 - 18,951,370UniSTSRnor5.0
RGSC_v3.4116,325,338 - 16,325,548UniSTSRGSC3.4
RGSC_v3.4116,325,337 - 16,325,548RGDRGSC3.4
RGSC_v3.1116,325,400 - 16,325,610RGD
Celera114,180,858 - 14,181,068UniSTS
RH 3.4 Map1165.0RGD
RH 3.4 Map1165.0UniSTS
RH 2.0 Map186.6RGD
SHRSP x BN Map112.5699RGD
FHH x ACI Map114.85RGD
Cytogenetic Map1p12UniSTS
RH131918  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,891,833 - 15,892,037 (+)MAPPERmRatBN7.2
Rnor_6.0116,607,096 - 16,607,299NCBIRnor6.0
Rnor_6.0117,630,287 - 17,630,490NCBIRnor6.0
Rnor_5.0119,154,974 - 19,155,177UniSTSRnor5.0
Rnor_5.0119,085,724 - 19,085,927UniSTSRnor5.0
RGSC_v3.4116,459,142 - 16,459,345UniSTSRGSC3.4
Celera114,312,190 - 14,312,393UniSTS
RH 3.4 Map1148.81UniSTS
Cytogenetic Map1p12UniSTS
RH143155  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,890,892 - 15,891,036 (+)MAPPERmRatBN7.2
Rnor_6.0116,606,155 - 16,606,298NCBIRnor6.0
Rnor_6.0117,629,346 - 17,629,489NCBIRnor6.0
Rnor_5.0119,154,033 - 19,154,176UniSTSRnor5.0
Rnor_5.0119,084,783 - 19,084,926UniSTSRnor5.0
RGSC_v3.4116,458,201 - 16,458,344UniSTSRGSC3.4
Celera114,311,249 - 14,311,392UniSTS
RH 3.4 Map1164.8UniSTS
Cytogenetic Map1p12UniSTS
AW531129  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,842,604 - 15,842,780 (+)MAPPERmRatBN7.2
Rnor_6.0116,557,631 - 16,557,806NCBIRnor6.0
Rnor_5.0119,036,259 - 19,036,434UniSTSRnor5.0
RGSC_v3.4116,410,059 - 16,410,234UniSTSRGSC3.4
Celera114,263,104 - 14,263,279UniSTS
RH 3.4 Map1165.12UniSTS
Cytogenetic Map1p12UniSTS
BE121279  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,879,013 - 15,879,217 (+)MAPPERmRatBN7.2
Rnor_6.0117,617,467 - 17,617,670NCBIRnor6.0
Rnor_6.0116,594,039 - 16,594,242NCBIRnor6.0
Rnor_5.0119,142,154 - 19,142,357UniSTSRnor5.0
Rnor_5.0119,072,667 - 19,072,870UniSTSRnor5.0
RGSC_v3.4116,446,322 - 16,446,525UniSTSRGSC3.4
Celera114,299,370 - 14,299,573UniSTS
RH 3.4 Map1165.41UniSTS
Cytogenetic Map1p12UniSTS
RH137467  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,882,699 - 15,882,883 (+)MAPPERmRatBN7.2
Rnor_6.0116,597,725 - 16,597,908NCBIRnor6.0
Rnor_6.0117,621,153 - 17,621,336NCBIRnor6.0
Rnor_5.0119,145,840 - 19,146,023UniSTSRnor5.0
Rnor_5.0119,076,353 - 19,076,536UniSTSRnor5.0
RGSC_v3.4116,450,008 - 16,450,191UniSTSRGSC3.4
Celera114,303,056 - 14,303,239UniSTS
Cytogenetic Map1p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001002277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AH011785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY647140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000019076   ⟹   ENSRNOP00000019077
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl115,762,462 - 15,886,927 (+)Ensembl
Rnor_6.0 Ensembl116,478,127 - 16,601,769 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000075461   ⟹   ENSRNOP00000067868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl117,602,281 - 17,625,197 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095156   ⟹   ENSRNOP00000086069
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl115,762,462 - 15,891,041 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097444   ⟹   ENSRNOP00000080424
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl115,762,462 - 15,891,041 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097948   ⟹   ENSRNOP00000096340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl115,762,462 - 15,869,659 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100225   ⟹   ENSRNOP00000090824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl115,762,462 - 15,891,041 (+)Ensembl
RefSeq Acc Id: NM_001002277   ⟹   NP_001002277
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,582,031 - 17,710,755 (+)NCBI
mRatBN7.2115,762,485 - 15,891,213 (+)NCBI
Rnor_6.0116,478,127 - 16,601,769 (+)NCBI
Rnor_5.0119,111,106 - 19,149,884 (+)NCBI
RGSC_v3.4116,332,801 - 16,454,055 (+)RGD
Celera114,188,321 - 14,307,100 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063263007   ⟹   XP_063119077
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,581,411 - 17,707,593 (+)NCBI
RefSeq Acc Id: XM_063263009   ⟹   XP_063119079
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,581,882 - 17,707,593 (+)NCBI
RefSeq Acc Id: XM_063263011   ⟹   XP_063119081
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,581,882 - 17,711,775 (+)NCBI
RefSeq Acc Id: XM_063263018   ⟹   XP_063119088
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,580,859 - 17,711,775 (+)NCBI
RefSeq Acc Id: XM_063263023   ⟹   XP_063119093
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,581,411 - 17,711,775 (+)NCBI
RefSeq Acc Id: XM_063263025   ⟹   XP_063119095
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,581,882 - 17,711,775 (+)NCBI
RefSeq Acc Id: XM_063263027   ⟹   XP_063119097
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,581,411 - 17,706,286 (+)NCBI
RefSeq Acc Id: XM_063263028   ⟹   XP_063119098
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,581,411 - 17,683,400 (+)NCBI
RefSeq Acc Id: XM_063263029   ⟹   XP_063119099
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,599,366 - 17,707,593 (+)NCBI
RefSeq Acc Id: XM_063263033   ⟹   XP_063119103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,632,623 - 17,711,775 (+)NCBI
RefSeq Acc Id: XR_010052942
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,581,411 - 17,639,578 (+)NCBI
RefSeq Acc Id: NP_001002277   ⟸   NM_001002277
- UniProtKB: Q6DTM3 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019077   ⟸   ENSRNOT00000019076
Ensembl Acc Id: ENSRNOP00000067868   ⟸   ENSRNOT00000075461
Ensembl Acc Id: ENSRNOP00000080424   ⟸   ENSRNOT00000097444
Ensembl Acc Id: ENSRNOP00000090824   ⟸   ENSRNOT00000100225
Ensembl Acc Id: ENSRNOP00000096340   ⟸   ENSRNOT00000097948
Ensembl Acc Id: ENSRNOP00000086069   ⟸   ENSRNOT00000095156
RefSeq Acc Id: XP_063119088   ⟸   XM_063263018
- Peptide Label: isoform X2
- UniProtKB: Q6DTM3 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063119093   ⟸   XM_063263023
- Peptide Label: isoform X3
- UniProtKB: Q6DTM3 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063119077   ⟸   XM_063263007
- Peptide Label: isoform X1
- UniProtKB: F1M9F9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119097   ⟸   XM_063263027
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A5B3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119098   ⟸   XM_063263028
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AF27 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119081   ⟸   XM_063263011
- Peptide Label: isoform X2
- UniProtKB: Q6DTM3 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063119095   ⟸   XM_063263025
- Peptide Label: isoform X3
- UniProtKB: Q6DTM3 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063119079   ⟸   XM_063263009
- Peptide Label: isoform X1
- UniProtKB: F1M9F9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119099   ⟸   XM_063263029
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063119103   ⟸   XM_063263033
- Peptide Label: isoform X7
Protein Domains
SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RE04-F1-model_v2 AlphaFold M0RE04 1-141 view protein structure
AF-Q6DTM3-F1-model_v2 AlphaFold Q6DTM3 1-1047 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303040 AgrOrtholog
BioCyc Gene G2FUF-62184 BioCyc
Ensembl Genes ENSRNOG00000013969 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000046617 Ensembl
Ensembl Transcript ENSRNOT00000019076.7 UniProtKB/TrEMBL
  ENSRNOT00000095156.1 UniProtKB/TrEMBL
  ENSRNOT00000097444.1 UniProtKB/TrEMBL
  ENSRNOT00000097948.1 UniProtKB/TrEMBL
  ENSRNOT00000100225.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AHI1_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cilium-Associated_Jouberin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:308923 UniProtKB/Swiss-Prot
NCBI Gene 308923 ENTREZGENE
PANTHER JOUBERIN UniProtKB/Swiss-Prot
  JOUBERIN UniProtKB/Swiss-Prot
  JOUBERIN UniProtKB/TrEMBL
  JOUBERIN UniProtKB/TrEMBL
Pfam SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ahi1 PhenoGen
PRINTS SH3DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013969 RatGTEx
  ENSRNOG00000046617 RatGTEx
SMART SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZQ93_RAT UniProtKB/TrEMBL
  A0A8I6A5B3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AF27 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AT56_RAT UniProtKB/TrEMBL
  AHI1_RAT UniProtKB/Swiss-Prot
  F1M9F9 ENTREZGENE, UniProtKB/TrEMBL
  Q6DTM3 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Ahi1  Abelson helper integration site 1  LOC103690149  jouberin-like  Data merged from RGD:9410822 737654 PROVISIONAL
2014-08-25 LOC103690149  jouberin-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-02-14 Ahi1  Abelson helper integration site 1      Symbol and Name status set to provisional 70820 PROVISIONAL