Irf9 (interferon regulatory factor 9)

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Gene: Irf9 (interferon regulatory factor 9) Rattus norvegicus

Analyze

Symbol:

Irf9

Name:

interferon regulatory factor 9

RGD ID:

1308766

Description:

Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in immune system process and type I interferon production. Predicted to localize to cytosol and nucleus. Human ortholog(s) of this gene implicated in immunodeficiency 65. Orthologous to human IRF9 (interferon regulatory factor 9); PARTICIPATES IN type II interferon signaling pathway; hepatitis C pathway; influenza A pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

interferon dependent positive acting transcription factor 3 gamma; Isgf3g; LOC305896

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	15	34,282,936 - 34,288,981 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	34,282,936 - 34,288,138 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	38,172,683 - 38,179,176 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	33,739,755 - 33,744,958 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	15	33,755,454 - 33,760,657 (+)	NCBI
Celera	15	28,671,799 - 28,677,002 (+)	NCBI		Celera
Cytogenetic Map	15	p13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

immunodeficiency 65 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4-dinitrotoluene (EXP)

2-methylcholine (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,3',5,5'-tetrabromobisphenol A (EXP)

3,4-methylenedioxymethamphetamine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4-amino-2,6-dinitrotoluene (EXP)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acetylsalicylic acid (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bucladesine (ISO)

cadmium dichloride (EXP)

carbon nanotube (ISO)

clofibrate (ISO)

cocaine (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

diethyl maleate (EXP)

dorsomorphin (ISO)

elemental selenium (ISO)

ellagic acid (ISO)

Enterolactone (ISO)

enzyme inhibitor (ISO)

ethyl methanesulfonate (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

gentamycin (EXP)

geraniol (ISO)

indometacin (ISO)

linuron (ISO)

lipopolysaccharide (ISO)

medroxyprogesterone acetate (ISO)

methapyrilene (EXP,ISO)

nickel atom (ISO)

ozone (ISO)

paracetamol (ISO)

pentachlorophenol (ISO)

phenylmercury acetate (ISO)

phenytoin (EXP)

poly(I:C) (ISO)

propiconazole (ISO)

resveratrol (ISO)

rotenone (EXP)

Salinomycin (ISO)

SB 431542 (ISO)

selenium atom (ISO)

serpentine asbestos (ISO)

silicon dioxide (ISO)

succimer (ISO)

sunitinib (ISO)

tamibarotene (ISO)

tamoxifen (ISO)

tert-butyl hydroperoxide (ISO)

testosterone enanthate (ISO)

tetrachloromethane (EXP,ISO)

titanium dioxide (ISO)

tofacitinib (ISO)

valproic acid (ISO)

vancomycin (ISO)

vitamin E (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

immune system process (IBA)

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

cytosol (IEA,ISO)

nucleus (IBA)

Molecular Function

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA,ISO)

sequence-specific double-stranded DNA binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

hepatitis C pathway (IEA)

influenza A pathway (IEA)

Jak-Stat signaling pathway (IEA)

measles pathway (IEA)

type II interferon signaling pathway (ISO)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA data from the GO Consortium
3.	MGD data from the GO Consortium
4.	Pipeline to import KEGG annotations from KEGG into RGD
5.	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6.	RGD automated data pipeline
7.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15800576	PMID:24882218	PMID:25150882	PMID:25319116	PMID:29480757

Genomics

Comparative Map Data

Irf9
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	15	34,282,936 - 34,288,981 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	34,282,936 - 34,288,138 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	38,172,683 - 38,179,176 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	33,739,755 - 33,744,958 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	15	33,755,454 - 33,760,657 (+)	NCBI
Celera	15	28,671,799 - 28,677,002 (+)	NCBI		Celera
Cytogenetic Map	15	p13	NCBI

IRF9
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	14	24,161,265 - 24,166,565 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	14	24,161,265 - 24,166,565 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	14	24,630,422 - 24,635,774 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	23,700,262 - 23,705,614 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	14	23,700,363 - 23,705,612	NCBI
Celera	14	4,494,890 - 4,500,242 (+)	NCBI
Cytogenetic Map	14	q12	NCBI
HuRef	14	4,745,386 - 4,750,738 (+)	NCBI		HuRef
CHM1_1	14	24,629,072 - 24,634,424 (+)	NCBI		CHM1_1

Irf9
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	55,841,442 - 55,847,487 (+)	NCBI	GRCm39		mm39
GRCm38	14	55,603,985 - 55,610,030 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	55,603,571 - 55,610,030 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	56,222,822 - 56,228,867 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	14	54,558,650 - 54,564,101 (+)	NCBI			mm8
Celera	14	53,409,045 - 53,415,090 (+)	NCBI		Celera
Cytogenetic Map	14	C3	NCBI
cM Map	14	28.19	NCBI

Irf9
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	36,234,077 - 36,239,500 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	36,233,633 - 36,239,916 (-)	NCBI	ChiLan1.0	ChiLan1.0

IRF9
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	14	23,061,994 - 23,067,824 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	23,061,990 - 23,067,824 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	14	4,937,068 - 4,942,870 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

IRF9
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	4,152,146 - 4,157,201 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Irf9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936722	380,193 - 385,887 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IRF9
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	75,126,609 - 75,139,639 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	75,133,800 - 75,139,641 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	80,405,098 - 80,410,938 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IRF9
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	1,146,116 - 1,151,622 (+)	NCBI
ChlSab1.1 Ensembl	24	1,146,618 - 1,151,546 (+)	Ensembl

Irf9
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624820	8,369,830 - 8,376,593 (-)	NCBI

Position Markers

RH130362

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	15	34,288,056 - 34,288,265	NCBI	Rnor6.0
Rnor_5.0	15	38,178,251 - 38,178,460	UniSTS	Rnor5.0
RGSC_v3.4	15	33,744,875 - 33,745,084	UniSTS	RGSC3.4
Celera	15	28,676,919 - 28,677,128	UniSTS
Cytogenetic Map	15	p13	UniSTS
RH 3.4 Map	15	260.91	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
9589149	Insul29	Insulin level QTL 29	9.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	15	1	37708474	Rat
8552920	Pigfal8	Plasma insulin-like growth factor 1 level QTL 8	3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	15	1	37708474	Rat
8694361	Abfw6	Abdominal fat weight QTL 6	10.2	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	15	1	37708474	Rat
731170	Pur3	Proteinuria QTL 3	2.3	0.0005	urine protein amount (VT:0005160)	urine protein excretion rate (CMO:0000759)	15	1	42844179	Rat
1641887	Alcrsp14	Alcohol response QTL 14			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	15	1	43521446	Rat
2298549	Neuinf12	Neuroinflammation QTL 12	3.5		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	15	1	62301382	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2327877	53535766	Rat
10401805	Kidm51	Kidney mass QTL 51			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	15	3881131	48881131	Rat
1582251	Gluco24	Glucose level QTL 24	3.2	0.0008	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	15	10719191	55719191	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	15492360	72568189	Rat
9590272	Scort14	Serum corticosterone level QTL 14	2.78	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	15	16980907	61980907	Rat
8694427	Bw163	Body weight QTL 163	4.82	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	15	16980907	61980907	Rat
2300167	Bmd63	Bone mineral density QTL 63	5.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	15	17249641	62249641	Rat
2300173	Bmd62	Bone mineral density QTL 62	12.8	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	15	17249641	62249641	Rat
2293688	Bss29	Bone structure and strength QTL 29	5.31	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	15	17249641	62249641	Rat
1331729	Rf42	Renal function QTL 42	3.071		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	15	18093208	81255430	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	18513913	88036354	Rat
631550	Bw7	Body weight QTL 7	3.6		body mass (VT:0001259)	body weight (CMO:0000012)	15	21021342	41082727	Rat
2324620	Coatc3	Coat color QTL 3			coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	15	21021342	52831189	Rat
10755503	Bp391	Blood pressure QTL 391	2.37		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	15	23778969	46825072	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	26381041	106550657	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	26381041	106550657	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	26381041	106550657	Rat
10054130	Srcrt8	Stress Responsive Cort QTL 8	2.18	0.0085	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	15	28709741	73709741	Rat
1582214	Stl21	Serum triglyceride level QTL 21	3.1	0.022	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	15	33219101	89640841	Rat
1582227	Gluco30	Glucose level QTL 30	3.6	0.0003	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	15	33219101	89640841	Rat
1582228	Epfw3	Epididymal fat weight QTL 3	4.1	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	33219101	89640841	Rat
1582242	Gluco28	Glucose level QTL 28	3.3	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	15	33219101	89640841	Rat
1582244	Bw79	Body weight QTL 79	4	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	33219101	89640841	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	44
Count of miRNA genes:	40
Interacting mature miRNAs:	44
Transcripts:	ENSRNOT00000026364
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	36	50	35	19	35	2	3	71	33	34	11	2
Low		7	7	6		6	6	8	3	2	7		6
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001012041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006251974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006251975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770679	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AABR07072457	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01083058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC079454	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474049	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000026364 ⟹ ENSRNOP00000026364

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	15	34,282,936 - 34,288,138 (+)	Ensembl

RefSeq Acc Id:

NM_001012041 ⟹ NP_001012041

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	15	34,282,936 - 34,288,139 (+)	NCBI
Rnor_5.0	15	38,172,683 - 38,179,176 (+)	NCBI
RGSC_v3.4	15	33,739,755 - 33,744,958 (+)	RGD
Celera	15	28,671,799 - 28,677,002 (+)	RGD

Sequence:

show sequence

GGTACATCCTCGGTCGCTCAGGATGGCCACAGGCAAAGCACGCTGTACCCGAAAGCTCCGGAAC
TGGATAGTGGAACAGGTGGAAAGTGGGCAGTTCCCAGGGGTGTGCTGGGACGACGCAGCCAAGA
CCATGTTCCGGATTCCCTGGAAGCACGCAGGCAAGCAAGACTTCCGAGAAGACCAGGATGCTGC
CATATTCAAGGCCTGGGCACTGTTTAAGGAAAAGCACAAAGACGGGGACATAGGAAACCCTGCT
GTCTGGAAGACTCGCCTACGCTGTGCCCTCAACAAGAGTTCCGAATTTGAGGAGGTTCCCGAGA
GAGGCCGGATGGATGTTGCAGAACCCTACAAAGTATATCGAATACTGCCAGCAGGAACCCTCCC
CACCCAACCAAGAAACCAGAAATCGCCATTCAAGCGAAGTATCAGTTCTGTGTCACCTGAGAGG
GGAGAGTGTAAGGAAAATGGGATTGTAAGCCACTCAGACAGCGGCAGCAATGTCTGTGGTGGTG
GCAGCAACGGTGGCGGCAGCAGTGACAGCTGTGGCAGCACCAGCAGCTCTGAGCTAGAGGAAGG
AGCTGGCACAACTGAAGCCACCGTTCAAGAGGACCCAGTGTTCATGGAGAATCCGCTTCCTCCG
AACTCAGACTACTCGCTGCTGCTCACCTTCATCTATGGCGGGCGCGTGGTGCATGAGATCCAGG
TGCACAGCCTAGACTGTCGGCTTGTGGCTGAGCCCTCAGACCCGGAGAGCAGCATGGTGCAGCA
GGTGGTGTTTCCCAGACCTGACCCACTGGAGCCCACCCAGAGCCTGCTGAATCAGCTCGAGAGA
GGCATCCTGGTGGCCAGCAATTCCAGAGGCCTCTTTGTTCAGCGCCTCTGCCCCATCCCCATCT
CCTGGAACGCACCCGAGGCCCCACCTGGGCCTGGGCCTCATCTGCTGCCCAGCAATAAGTGTGT
GGAGCTCTTCAGTACCACATACTTCTGTAGAGATTTGGCCCAGTACTTCCAGGGCCAGGGACCT
CTACCCAAGTACCAAGCAACACTGCATTTCTGGGACAGGAGTCCTAGCTCTAGCTATACCCAAG
AGAATCTTATCACGGTGCGGATGGAGCAGGCCTTTGCCCGAAATTTACTAGAGAAGATTCCAGA
AGAGGAGAAAGCTGCCTTGTTCCTGGTACAGCACACAGAGCACCAACCTGCCACTCTCGCACTC
TGATCCTCGGGTCCCCGTTGAAATAGACTTGTTCTCCACACCGTTGGTCTGCCTGCTTTCGTGA
TGATTCTTATCACTGTGGGCTTTCCAATGTGGCCAAGAGAAAGTGCAAGGATAACTTTTATCTT
CAAAAACTATTCTGAGAGCCAGACTCGTTGGTGGATATTCATAATCTCAGCACTGGATTATGAG
TTCAAGGACAACCTGGGGGAGACTTCTATTTCCTTTTTCTAAAGCTATATCTTCTTTCATTTCT
AAGAAACTGGAAAGTTCCAAAGGGTGTGATCTCAGAGGAAATTTTGCTATCCTCCCAATCCCTA
ACTCTAAACCTAAGCTGTATGTATGTGTGTATGTATATATATAAATATATATTTCCCCCCTCAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006251974 ⟹ XP_006252036

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	15	34,282,964 - 34,288,981 (+)	NCBI
Rnor_5.0	15	38,172,683 - 38,179,176 (+)	NCBI

Sequence:

show sequence

CAGTTCTGCAGGGGGACCAACTGGAAGCACTGAGAGGGGGCTGGTGAGGGCTCCCCAGGGCCCT
GGGCTACAGGGAGAGTCAGGCTGGTGAATCTGAAAATAGGTTTGGCCTGAGTGAGAAACTGATA
CTGGGCCTGTGGGCAGGGCAGGAGGGGGAGGGACTGCTGCCAACTAGACTGTTGAGGAAGGCCC
TTTGTGGGCCTCAGTTAACCTTTGTTTTTCTTGCCTCTGGCCCTGCCCACTTCTGCTTCAGCTC
CACCCTTGCCCCCAGCTGCCCCACCTACCCCACTAGCAACAGGGGAATGGTAGTGAGATGGTTG
GTCGGCTGGGGAGATAGATGCCTTAACTGCCAATGTCCACTCTGCAGATGCCTGGGATCTAAAC
AGTCTGATACAAGGAACAGGTCATTGAGGGGATTCTCCCAAGTAACACATCTGAAACACTTCGA
CTTACTAAGACCAATGTCCGTGGTTCCCTTTCAGGATGGCCACAGGCAAAGCACGCTGTACCCG
AAAGCTCCGGAACTGGATAGTGGAACAGGTGGAAAGTGGGCAGTTCCCAGGGGTGTGCTGGGAC
GACGCAGCCAAGACCATGTTCCGGATTCCCTGGAAGCACGCAGGCAAGCAAGACTTCCGAGAAG
ACCAGGATGCTGCCATATTCAAGGCCTGGGCACTGTTTAAGGAAAAGCACAAAGACGGGGACAT
AGGAAACCCTGCTGTCTGGAAGACTCGCCTACGCTGTGCCCTCAACAAGAGTTCCGAATTTGAG
GAGGTTCCCGAGAGAGGCCGGATGGATGTTGCAGAACCCTACAAAGTATATCGAATACTGCCAG
CAGGAACCCTCCCCACCCAACCAAGAAACCAGAAATCGCCATTCAAGCGAAGTATCAGTTCTGT
GTCACCTGAGAGGGGAGAGTGTAAGGAAAATGGGATTGTAAGCCACTCAGACAGCGGCAGCAAT
GTCTGTGGTGGTGGCAGCAACGGTGGCGGCAGCAGTGACAGCTGTGGCAGCACCAGCAGCTCTG
AGCTAGAGGAAGGAGCTGGCACAACTGAAGCCACCGTTCAAGAGGACCCAGTGTTCATGGAGAA
TCCGCTTCCTCCGAACTCAGACTACTCGCTGCTGCTCACCTTCATCTATGGCGGGCGCGTGGTG
CATGAGATCCAGGTGCACAGCCTAGACTGTCGGCTTGTGGCTGAGCCCTCAGACCCGGAGAGCA
GCATGGTGCAGCAGGTGGTGTTTCCCAGACCTGACCCACTGGAGCCCACCCAGAGCCTGCTGAA
TCAGCTCGAGAGAGGCATCCTGGTGGCCAGCAATTCCAGAGGCCTCTTTGTTCAGCGCCTCTGC
CCCATCCCCATCTCCTGGAACGCACCCGAGGCCCCACCTGGGCCTGGGCCTCATCTGCTGCCCA
GCAATAAGTGTGTGGAGCTCTTCAGTACCACATACTTCTGTAGAGATTTGGCCCAGTACTTCCA
GGGCCAGGGACCTCTACCCAAGTACCAAGCAACACTGCATTTCTGGGACAGGAGTCCTAGCTCT
AGCCATACCCAAGAGAATCTTATCACGGTGCGGATGGAGCAGGCCTTTGCCCGAAATTTACTAG
AGAAGATTCCAGAAGAGGAGAAAGCTGCCTTGTTCCTGGTACAGCACACAGAGCACCAACCTGC
CACTCTCGCACTCTGATCCTCGGGTCCCCGTTGAAATAGACTTGTTCTCCACACCGTTGGTCTG
CCTGCTTTCGTGATGATTCTTATCACTGTGGGCTTTCCAATGTGGCCAAGAGAAAGTGCAAGGA
TAACTTTTATCTTCAAAAACTATTCTGAGAGCCAGACTCGTTGGTGGATATTCATAATCTCAGC
ACTGGATTATGAGTTCAAGGACAACCTGGGGGAGACTTCTATTTCCTTTTTCTAAAGCTATATC
TTCTTTCATTTCTAAGAAACTGGAAAGTTCCAAAGGGTGTGATCTCAGAGGAAATTTTGCTATC
CTCCCAATCCCTAACTCTAAACCTAAGCTGTATGTATGTGTGTATGTATATATATAAATATATA
TTTCCCCCCTCAGTTCTCACTAGAATAAAATAAAATTTAGCTGGGTGAGGTAGTACACACTCGG
CACATAGGAGTGTATGTGCAGAGGCAGGAAGATTGTGAGTTCAAATTCAAGGCCAGCCTTGGTG
ATACTGTCTGTCTCCAAACAGTAAATAAAAGCTTACTAAGAGAGAGAGATCAGGATCTGATTCG
TTAGGAGAGGGTGGCAGGGGTTAAGATGGAGACCAAGGTACCCAGTATCTGGGTTCTCTGTCAC
ATGGTGTTTCTGGGCCTAGCCAGAGTGCCATAGTCTCTAACCCATGGTGATTTCTCCTGCCCTA
GCCTCCTGAGTGTTGGGGTTCTGGGTGTACACCACTATGCCTGGCCGTACCCCCATGTCTCCCT
CCCTTTACTCTTTTTTCCAGTTGACCTTCCCGCCCCCCTTTTTTTTTCAGACTTGACCTGGTAC
TTCGAGGGTAAGGGGCCCCCACCCAAGTTACAGGCAACTGAGATTGGATTGGGGTCAACCTCTA
AGACAGGCACTGTTGCCTACAGGCAGACAGCACTATAGCCACAAGGCGGTTTGAATGAGATTAG
CCTCCATAGGCTCATATGTGAATTCTTGGTCCTCAGTGGACCCACCTGGGAAAGGTCAGGAGGT
GTGGCGTTGGATGAGGTGTGTCAGTCACTAGCCATGGGCTTTGAGGTTTCCCTGCTAGCACACT
CTCTGTGTCTCGTGCTTGTAAATCAGATGTAAGCTCTCAACCCCAGTACCATTCCTGGCTGCCT
GCCTGCTGCTGTGTTCACTGCCGTTTTGGTCACGGACTCTAAGCCTTTAGAAATGTGAGCCCCA
AATTAAACTTTGTCATTCCTAA

hide sequence

RefSeq Acc Id:

XM_006251975 ⟹ XP_006252037

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	15	34,283,566 - 34,288,981 (+)	NCBI
Rnor_5.0	15	38,172,683 - 38,179,176 (+)	NCBI

Sequence:

show sequence

CCTGGTGGTCAGAGGTTAGCAGGAGTTTCCCAAGTTGTTGGCTCTCCCTGGGCATGGTGTCACT
TATCCCTGATCCCAGCATTTCAGAAGCAGGATGGCCACAGGCAAAGCACGCTGTACCCGAAAGC
TCCGGAACTGGATAGTGGAACAGGTGGAAAGTGGGCAGTTCCCAGGGGTGTGCTGGGACGACGC
AGCCAAGACCATGTTCCGGATTCCCTGGAAGCACGCAGGCAAGCAAGACTTCCGAGAAGACCAG
GATGCTGCCATATTCAAGGCCTGGGCACTGTTTAAGGAAAAGCACAAAGACGGGGACATAGGAA
ACCCTGCTGTCTGGAAGACTCGCCTACGCTGTGCCCTCAACAAGAGTTCCGAATTTGAGGAGGT
TCCCGAGAGAGGCCGGATGGATGTTGCAGAACCCTACAAAGTATATCGAATACTGCCAGCAGGA
ACCCTCCCCACCCAACCAAGAAACCAGAAATCGCCATTCAAGCGAAGTATCAGTTCTGTGTCAC
CTGAGAGGGGAGAGTGTAAGGAAAATGGGATTGTAAGCCACTCAGACAGCGGCAGCAATGTCTG
TGGTGGTGGCAGCAACGGTGGCGGCAGCAGTGACAGCTGTGGCAGCACCAGCAGCTCTGAGCTA
GAGGAAGGAGCTGGCACAACTGAAGCCACCGTTCAAGAGGACCCAGTGTTCATGGAGAATCCGC
TTCCTCCGAACTCAGACTACTCGCTGCTGCTCACCTTCATCTATGGCGGGCGCGTGGTGCATGA
GATCCAGGTGCACAGCCTAGACTGTCGGCTTGTGGCTGAGCCCTCAGACCCGGAGAGCAGCATG
GTGCAGCAGGTGGTGTTTCCCAGACCTGACCCACTGGAGCCCACCCAGAGCCTGCTGAATCAGC
TCGAGAGAGGCATCCTGGTGGCCAGCAATTCCAGAGGCCTCTTTGTTCAGCGCCTCTGCCCCAT
CCCCATCTCCTGGAACGCACCCGAGGCCCCACCTGGGCCTGGGCCTCATCTGCTGCCCAGCAAT
AAGTGTGTGGAGCTCTTCAGTACCACATACTTCTGTAGAGATTTGGCCCAGTACTTCCAGGGCC
AGGGACCTCTACCCAAGTACCAAGCAACACTGCATTTCTGGGACAGGAGTCCTAGCTCTAGCCA
TACCCAAGAGAATCTTATCACGGTGCGGATGGAGCAGGCCTTTGCCCGAAATTTACTAGAGAAG
ATTCCAGAAGAGGAGAAAGCTGCCTTGTTCCTGGTACAGCACACAGAGCACCAACCTGCCACTC
TCGCACTCTGATCCTCGGGTCCCCGTTGAAATAGACTTGTTCTCCACACCGTTGGTCTGCCTGC
TTTCGTGATGATTCTTATCACTGTGGGCTTTCCAATGTGGCCAAGAGAAAGTGCAAGGATAACT
TTTATCTTCAAAAACTATTCTGAGAGCCAGACTCGTTGGTGGATATTCATAATCTCAGCACTGG
ATTATGAGTTCAAGGACAACCTGGGGGAGACTTCTATTTCCTTTTTCTAAAGCTATATCTTCTT
TCATTTCTAAGAAACTGGAAAGTTCCAAAGGGTGTGATCTCAGAGGAAATTTTGCTATCCTCCC
AATCCCTAACTCTAAACCTAAGCTGTATGTATGTGTGTATGTATATATATAAATATATATTTCC
CCCCTCAGTTCTCACTAGAATAAAATAAAATTTAGCTGGGTGAGGTAGTACACACTCGGCACAT
AGGAGTGTATGTGCAGAGGCAGGAAGATTGTGAGTTCAAATTCAAGGCCAGCCTTGGTGATACT
GTCTGTCTCCAAACAGTAAATAAAAGCTTACTAAGAGAGAGAGATCAGGATCTGATTCGTTAGG
AGAGGGTGGCAGGGGTTAAGATGGAGACCAAGGTACCCAGTATCTGGGTTCTCTGTCACATGGT
GTTTCTGGGCCTAGCCAGAGTGCCATAGTCTCTAACCCATGGTGATTTCTCCTGCCCTAGCCTC
CTGAGTGTTGGGGTTCTGGGTGTACACCACTATGCCTGGCCGTACCCCCATGTCTCCCTCCCTT
TACTCTTTTTTCCAGTTGACCTTCCCGCCCCCCTTTTTTTTTCAGACTTGACCTGGTACTTCGA
GGGTAAGGGGCCCCCACCCAAGTTACAGGCAACTGAGATTGGATTGGGGTCAACCTCTAAGACA
GGCACTGTTGCCTACAGGCAGACAGCACTATAGCCACAAGGCGGTTTGAATGAGATTAGCCTCC
ATAGGCTCATATGTGAATTCTTGGTCCTCAGTGGACCCACCTGGGAAAGGTCAGGAGGTGTGGC
GTTGGATGAGGTGTGTCAGTCACTAGCCATGGGCTTTGAGGTTTCCCTGCTAGCACACTCTCTG
TGTCTCGTGCTTGTAAATCAGATGTAAGCTCTCAACCCCAGTACCATTCCTGGCTGCCTGCCTG
CTGCTGTGTTCACTGCCGTTTTGGTCACGGACTCTAAGCCTTTAGAAATGTGAGCCCCAAATTA
AACTTTGTCATTCCTAA

hide sequence

RefSeq Acc Id:

XM_008770679 ⟹ XP_008768901

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	15	34,283,446 - 34,288,981 (+)	NCBI

Sequence:

show sequence

GTGTGATAACTTGGAATTTTAGAAAGAAATTTTAAGAATTAGTTTCTACCTCGGAGAATGCTGC
TAGAGAGAAAAGAACATGGAAGGGTCTTCAGGGAAGGGCCTTTGCATGAAGTTGGCCCTGGTGG
TCAGAGGATGGCCACAGGCAAAGCACGCTGTACCCGAAAGCTCCGGAACTGGATAGTGGAACAG
GTGGAAAGTGGGCAGTTCCCAGGGGTGTGCTGGGACGACGCAGCCAAGACCATGTTCCGGATTC
CCTGGAAGCACGCAGGCAAGCAAGACTTCCGAGAAGACCAGGATGCTGCCATATTCAAGGCCTG
GGCACTGTTTAAGGAAAAGCACAAAGACGGGGACATAGGAAACCCTGCTGTCTGGAAGACTCGC
CTACGCTGTGCCCTCAACAAGAGTTCCGAATTTGAGGAGGTTCCCGAGAGAGGCCGGATGGATG
TTGCAGAACCCTACAAAGTATATCGAATACTGCCAGCAGGAACCCTCCCCACCCAACCAAGAAA
CCAGAAATCGCCATTCAAGCGAAGTATCAGTTCTGTGTCACCTGAGAGGGGAGAGTGTAAGGAA
AATGGGATTGTAAGCCACTCAGACAGCGGCAGCAATGTCTGTGGTGGTGGCAGCAACGGTGGCG
GCAGCAGTGACAGCTGTGGCAGCACCAGCAGCTCTGAGCTAGAGGAAGGAGCTGGCACAACTGA
AGCCACCGTTCAAGAGGACCCAGTGTTCATGGAGAATCCGCTTCCTCCGAACTCAGACTACTCG
CTGCTGCTCACCTTCATCTATGGCGGGCGCGTGGTGCATGAGATCCAGGTGCACAGCCTAGACT
GTCGGCTTGTGGCTGAGCCCTCAGACCCGGAGAGCAGCATGGTGCAGCAGGTGGTGTTTCCCAG
ACCTGACCCACTGGAGCCCACCCAGAGCCTGCTGAATCAGCTCGAGAGAGGCATCCTGGTGGCC
AGCAATTCCAGAGGCCTCTTTGTTCAGCGCCTCTGCCCCATCCCCATCTCCTGGAACGCACCCG
AGGCCCCACCTGGGCCTGGGCCTCATCTGCTGCCCAGCAATAAGTGTGTGGAGCTCTTCAGTAC
CACATACTTCTGTAGAGATTTGGCCCAGTACTTCCAGGGCCAGGGACCTCTACCCAAGTACCAA
GCAACACTGCATTTCTGGGACAGGAGTCCTAGCTCTAGCCATACCCAAGAGAATCTTATCACGG
TGCGGATGGAGCAGGCCTTTGCCCGAAATTTACTAGAGAAGATTCCAGAAGAGGAGAAAGCTGC
CTTGTTCCTGGTACAGCACACAGAGCACCAACCTGCCACTCTCGCACTCTGATCCTCGGGTCCC
CGTTGAAATAGACTTGTTCTCCACACCGTTGGTCTGCCTGCTTTCGTGATGATTCTTATCACTG
TGGGCTTTCCAATGTGGCCAAGAGAAAGTGCAAGGATAACTTTTATCTTCAAAAACTATTCTGA
GAGCCAGACTCGTTGGTGGATATTCATAATCTCAGCACTGGATTATGAGTTCAAGGACAACCTG
GGGGAGACTTCTATTTCCTTTTTCTAAAGCTATATCTTCTTTCATTTCTAAGAAACTGGAAAGT
TCCAAAGGGTGTGATCTCAGAGGAAATTTTGCTATCCTCCCAATCCCTAACTCTAAACCTAAGC
TGTATGTATGTGTGTATGTATATATATAAATATATATTTCCCCCCTCAGTTCTCACTAGAATAA
AATAAAATTTAGCTGGGTGAGGTAGTACACACTCGGCACATAGGAGTGTATGTGCAGAGGCAGG
AAGATTGTGAGTTCAAATTCAAGGCCAGCCTTGGTGATACTGTCTGTCTCCAAACAGTAAATAA
AAGCTTACTAAGAGAGAGAGATCAGGATCTGATTCGTTAGGAGAGGGTGGCAGGGGTTAAGATG
GAGACCAAGGTACCCAGTATCTGGGTTCTCTGTCACATGGTGTTTCTGGGCCTAGCCAGAGTGC
CATAGTCTCTAACCCATGGTGATTTCTCCTGCCCTAGCCTCCTGAGTGTTGGGGTTCTGGGTGT
ACACCACTATGCCTGGCCGTACCCCCATGTCTCCCTCCCTTTACTCTTTTTTCCAGTTGACCTT
CCCGCCCCCCTTTTTTTTTCAGACTTGACCTGGTACTTCGAGGGTAAGGGGCCCCCACCCAAGT
TACAGGCAACTGAGATTGGATTGGGGTCAACCTCTAAGACAGGCACTGTTGCCTACAGGCAGAC
AGCACTATAGCCACAAGGCGGTTTGAATGAGATTAGCCTCCATAGGCTCATATGTGAATTCTTG
GTCCTCAGTGGACCCACCTGGGAAAGGTCAGGAGGTGTGGCGTTGGATGAGGTGTGTCAGTCAC
TAGCCATGGGCTTTGAGGTTTCCCTGCTAGCACACTCTCTGTGTCTCGTGCTTGTAAATCAGAT
GTAAGCTCTCAACCCCAGTACCATTCCTGGCTGCCTGCCTGCTGCTGTGTTCACTGCCGTTTTG
GTCACGGACTCTAAGCCTTTAGAAATGTGAGCCCCAAATTAAACTTTGTCATTCCTAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001012041	(Get FASTA)	NCBI Sequence Viewer
	XP_006252036	(Get FASTA)	NCBI Sequence Viewer
	XP_006252037	(Get FASTA)	NCBI Sequence Viewer
	XP_008768901	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79454	(Get FASTA)	NCBI Sequence Viewer
	EDM14250	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001012041 ⟸ NM_001012041

- UniProtKB:

Q68FP4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MATGKARCTRKLRNWIVEQVESGQFPGVCWDDAAKTMFRIPWKHAGKQDFREDQDAAIFKAWAL
FKEKHKDGDIGNPAVWKTRLRCALNKSSEFEEVPERGRMDVAEPYKVYRILPAGTLPTQPRNQK
SPFKRSISSVSPERGECKENGIVSHSDSGSNVCGGGSNGGGSSDSCGSTSSSELEEGAGTTEAT
VQEDPVFMENPLPPNSDYSLLLTFIYGGRVVHEIQVHSLDCRLVAEPSDPESSMVQQVVFPRPD
PLEPTQSLLNQLERGILVASNSRGLFVQRLCPIPISWNAPEAPPGPGPHLLPSNKCVELFSTTY
FCRDLAQYFQGQGPLPKYQATLHFWDRSPSSSYTQENLITVRMEQAFARNLLEKIPEEEKAALF
LVQHTEHQPATLAL

hide sequence

RefSeq Acc Id:	XP_006252036 ⟸ XM_006251974
- Peptide Label:	isoform X2
- UniProtKB:	G3V8J4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MATGKARCTRKLRNWIVEQVESGQFPGVCWDDAAKTMFRIPWKHAGKQDFREDQDAAIFKAWAL FKEKHKDGDIGNPAVWKTRLRCALNKSSEFEEVPERGRMDVAEPYKVYRILPAGTLPTQPRNQK SPFKRSISSVSPERGECKENGIVSHSDSGSNVCGGGSNGGGSSDSCGSTSSSELEEGAGTTEAT VQEDPVFMENPLPPNSDYSLLLTFIYGGRVVHEIQVHSLDCRLVAEPSDPESSMVQQVVFPRPD PLEPTQSLLNQLERGILVASNSRGLFVQRLCPIPISWNAPEAPPGPGPHLLPSNKCVELFSTTY FCRDLAQYFQGQGPLPKYQATLHFWDRSPSSSHTQENLITVRMEQAFARNLLEKIPEEEKAALF LVQHTEHQPATLAL hide sequence

RefSeq Acc Id:	XP_006252037 ⟸ XM_006251975
- Peptide Label:	isoform X2
- UniProtKB:	G3V8J4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MATGKARCTRKLRNWIVEQVESGQFPGVCWDDAAKTMFRIPWKHAGKQDFREDQDAAIFKAWAL FKEKHKDGDIGNPAVWKTRLRCALNKSSEFEEVPERGRMDVAEPYKVYRILPAGTLPTQPRNQK SPFKRSISSVSPERGECKENGIVSHSDSGSNVCGGGSNGGGSSDSCGSTSSSELEEGAGTTEAT VQEDPVFMENPLPPNSDYSLLLTFIYGGRVVHEIQVHSLDCRLVAEPSDPESSMVQQVVFPRPD PLEPTQSLLNQLERGILVASNSRGLFVQRLCPIPISWNAPEAPPGPGPHLLPSNKCVELFSTTY FCRDLAQYFQGQGPLPKYQATLHFWDRSPSSSHTQENLITVRMEQAFARNLLEKIPEEEKAALF LVQHTEHQPATLAL hide sequence

RefSeq Acc Id:

XP_008768901 ⟸ XM_008770679

- Peptide Label:

isoform X1

- Sequence:

show sequence

MLLERKEHGRVFREGPLHEVGPGGQRMATGKARCTRKLRNWIVEQVESGQFPGVCWDDAAKTMF
RIPWKHAGKQDFREDQDAAIFKAWALFKEKHKDGDIGNPAVWKTRLRCALNKSSEFEEVPERGR
MDVAEPYKVYRILPAGTLPTQPRNQKSPFKRSISSVSPERGECKENGIVSHSDSGSNVCGGGSN
GGGSSDSCGSTSSSELEEGAGTTEATVQEDPVFMENPLPPNSDYSLLLTFIYGGRVVHEIQVHS
LDCRLVAEPSDPESSMVQQVVFPRPDPLEPTQSLLNQLERGILVASNSRGLFVQRLCPIPISWN
APEAPPGPGPHLLPSNKCVELFSTTYFCRDLAQYFQGQGPLPKYQATLHFWDRSPSSSHTQENL
ITVRMEQAFARNLLEKIPEEEKAALFLVQHTEHQPATLAL

hide sequence

RefSeq Acc Id:

ENSRNOP00000026364 ⟸ ENSRNOT00000026364

Protein Domains

IRF tryptophan pentad repeat

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699676

Promoter ID:

EPDNEW_R10199

Type:

multiple initiation site

Name:

Irf9_1

Description:

interferon regulatory factor 9

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	15	34,282,920 - 34,282,980	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Damaging Variants

Assembly: Rnor_6.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
15	34287738	34287739	A	C	snv	SR/JrHsd (RGD)

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308766	AgrOrtholog
Ensembl Genes	ENSRNOG00000019478	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000026364	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000026364	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
	2.60.200.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7121327	IMAGE-MGC_LOAD
InterPro	Interferon_reg_fac_CS	UniProtKB/TrEMBL
	Interferon_reg_fact_DNA-bd_dom	UniProtKB/TrEMBL
	Interferon_reg_factor-3	UniProtKB/TrEMBL
	SMAD_dom-like	UniProtKB/TrEMBL
	SMAD_FHA_domain	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
KEGG Report	rno:305896	UniProtKB/TrEMBL
MGC_CLONE	MGC:95006	IMAGE-MGC_LOAD
NCBI Gene	305896	ENTREZGENE
PANTHER	PTHR11949	UniProtKB/TrEMBL
Pfam	IRF	UniProtKB/TrEMBL
	IRF-3	UniProtKB/TrEMBL
PhenoGen	Irf9	PhenoGen
PRINTS	INTFRNREGFCT	UniProtKB/TrEMBL
PROSITE	IRF_1	UniProtKB/TrEMBL
	IRF_2	UniProtKB/TrEMBL
SMART	IRF	UniProtKB/TrEMBL
	IRF-3	UniProtKB/TrEMBL
Superfamily-SCOP	SMAD_FHA	UniProtKB/TrEMBL
	SSF46785	UniProtKB/TrEMBL
UniGene	Rn.163277	ENTREZGENE
UniProt	G3V8J4	ENTREZGENE, UniProtKB/TrEMBL
	Q68FP4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-04	Irf9	interferon regulatory factor 9	Isgf3g	interferon dependent positive acting transcription factor 3 gamma	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Isgf3g	interferon dependent positive acting transcription factor 3 gamma	Isgf3g_predicted	interferon dependent positive acting transcription factor 3 gamma (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Isgf3g_predicted	interferon dependent positive acting transcription factor 3 gamma (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)