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Gene: Dusp4 (dual specificity phosphatase 4) Rattus norvegicus
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Symbol: Dusp4
Name: dual specificity phosphatase 4
Description: Exhibits MAP kinase tyrosine/serine/threonine phosphatase activity and protein tyrosine/threonine phosphatase activity. Involved in protein dephosphorylation. Predicted to localize to the cytoplasm and nucleoplasm. Orthologous to human DUSP4 (dual specificity phosphatase 4); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH (+)-schisandrin B; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: dual specificity protein phosphatase 4; MAP kinase phosphatase; MAP kinase phosphatase 2; mitogen-activated protein kinase phosphatase 2; Mkp-2; Mkp2
Orthologs:
Homo sapiens (human) : DUSP4 (dual specificity phosphatase 4)  HGNC  Alliance
Mus musculus (house mouse) : Dusp4 (dual specificity phosphatase 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dusp4 (dual specificity phosphatase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : DUSP4 (dual specificity phosphatase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dusp4 (dual specificity phosphatase 4)
Sus scrofa (pig) : DUSP4 (dual specificity phosphatase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01661,080,767 - 61,090,973 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1661,078,175 - 61,091,169 (-)Ensembl
Rnor_5.01660,749,903 - 60,769,025 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41661,109,626 - 61,119,981 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11661,109,700 - 61,120,056 (-)NCBI
Celera1655,427,894 - 55,438,053 (-)NCBICelera
Cytogenetic Map16q12.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Dusp4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620625
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.