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Gene: Ccnb1 (cyclin B1) Rattus norvegicus
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Symbol: Ccnb1
Name: cyclin B1
Description: Exhibits protein kinase binding activity. Contributes to histone kinase activity. Involved in several processes, including gamete generation; regulation of gene expression; and regulation of protein phosphorylation. Localizes to the cytoplasm and nucleus. Predicted to colocalize with the mitochondrial matrix. Biomarker of visual epilepsy. Human ortholog(s) of this gene implicated in breast cancer and prostate cancer. Orthologous to human CCNB1 (cyclin B1); PARTICIPATES IN cell cycle pathway, mitotic; G1/S transition pathway; G2/M checkpoint pathway; INTERACTS WITH (-)-citrinin; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G2/mitotic-specific cyclin-B1
Orthologs:
Homo sapiens (human) : CCNB1 (cyclin B1)  HGNC  Alliance
Mus musculus (house mouse) : Ccnb1 (cyclin B1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccnb1 (cyclin B1)
Pan paniscus (bonobo/pygmy chimpanzee) : CCNB1 (cyclin B1)
Canis lupus familiaris (dog) : CCNB1 (cyclin B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccnb1 (cyclin B1)
Sus scrofa (pig) : CCNB1 (cyclin B1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0230,782,133 - 30,791,106 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0249,941,586 - 49,948,770 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4231,574,600 - 31,581,784 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1231,493,947 - 31,502,123 (-)NCBI
Celera227,925,441 - 27,934,414 (-)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ccnb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2291
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.