Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ccnb1 (cyclin B1) Rattus norvegicus
Symbol: Ccnb1
Name: cyclin B1
RGD ID: 2291
Description: Exhibits protein kinase binding activity. Involved in several processes, including gamete generation; regulation of gene expression; and regulation of protein phosphorylation. Localizes to cytoplasm and nucleus. Predicted to colocalize with mitochondrial matrix. Biomarker of visual epilepsy. Human ortholog(s) of this gene implicated in breast cancer and prostate cancer. Orthologous to human CCNB1 (cyclin B1); PARTICIPATES IN cell cycle pathway, mitotic; G1/S transition pathway; G2/M checkpoint pathway; INTERACTS WITH (-)-citrinin; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G2/mitotic-specific cyclin-B1
Homo sapiens (human) : CCNB1 (cyclin B1)  HGNC  Alliance
Mus musculus (house mouse) : Ccnb1 (cyclin B1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccnb1 (cyclin B1)
Pan paniscus (bonobo/pygmy chimpanzee) : CCNB1 (cyclin B1)
Canis lupus familiaris (dog) : CCNB1 (cyclin B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccnb1 (cyclin B1)
Sus scrofa (pig) : CCNB1 (cyclin B1)
Chlorocebus sabaeus (African green monkey) : CCNB1 (cyclin B1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0230,782,133 - 30,791,106 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl230,783,915 - 30,791,221 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0249,941,586 - 49,948,770 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4231,574,600 - 31,581,784 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1231,493,947 - 31,502,123 (-)NCBI
Celera227,925,441 - 27,934,414 (-)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ccnb1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2291
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.