CCNB1 (cyclin B1) - Rat Genome Database

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Gene: CCNB1 (cyclin B1) Canis lupus familiaris
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Symbol: CCNB1
Name: cyclin B1
RGD ID: 12274567
Description: ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase activator activity (ortholog); histone kinase activity (ortholog); patched binding (ortholog); INVOLVED IN cellular response to fatty acid (ortholog); cellular response to hypoxia (ortholog); cellular response to iron(III) ion (ortholog); ASSOCIATED WITH breast cancer (ortholog); cervical cancer (ortholog); COVID-19 (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: G2/mitotic-specific cyclin-B1; LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Related Pseudogenes: LOC485338  
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1254,256,957 - 54,264,749 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha251,223,809 - 51,231,591 (+)NCBI
ROS_Cfam_1.0254,767,756 - 54,775,584 (+)NCBI
UMICH_Zoey_3.1251,827,069 - 51,834,879 (+)NCBI
UNSW_CanFamBas_1.0252,602,043 - 52,609,862 (+)NCBI
UU_Cfam_GSD_1.0253,489,618 - 53,497,458 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to fatty acid  (ISO)
cellular response to hypoxia  (ISO)
cellular response to iron(III) ion  (ISO)
cellular response to organic cyclic compound  (ISO)
digestive tract development  (ISO)
histone H3-S10 phosphorylation involved in chromosome condensation  (ISO)
in utero embryonic development  (ISO)
mitotic cell cycle  (ISO)
mitotic cell cycle phase transition  (IBA)
mitotic metaphase plate congression  (IBA)
mitotic spindle organization  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of meiotic cell cycle process involved in oocyte maturation  (ISO)
negative regulation of protein phosphorylation  (ISO)
oocyte maturation  (ISO)
positive regulation of attachment of spindle microtubules to kinetochore  (ISO)
positive regulation of cardiac muscle cell proliferation  (ISO)
positive regulation of cell cycle  (ISO)
positive regulation of fibroblast proliferation  (ISO)
positive regulation of G2/M transition of mitotic cell cycle  (ISO)
positive regulation of histone phosphorylation  (ISO)
positive regulation of mitochondrial ATP synthesis coupled electron transport  (ISO)
positive regulation of mitotic cell cycle  (ISO)
positive regulation of mRNA 3'-end processing  (ISO)
protein phosphorylation  (ISO)
protein-containing complex assembly  (ISO)
regulation of cell cycle  (ISO)
regulation of chromosome condensation  (ISO)
regulation of cyclin-dependent protein serine/threonine kinase activity  (IBA)
regulation of mitotic cell cycle spindle assembly checkpoint  (ISO)
response to DDT  (ISO)
response to mechanical stimulus  (ISO)
response to toxic substance  (ISO)
response to xenobiotic stimulus  (ISO)
spermatogenesis  (ISO)
tissue regeneration  (ISO)
ventricular cardiac muscle cell development  (ISO)

Cellular Component

References

Genomics

Comparative Map Data
CCNB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1254,256,957 - 54,264,749 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha251,223,809 - 51,231,591 (+)NCBI
ROS_Cfam_1.0254,767,756 - 54,775,584 (+)NCBI
UMICH_Zoey_3.1251,827,069 - 51,834,879 (+)NCBI
UNSW_CanFamBas_1.0252,602,043 - 52,609,862 (+)NCBI
UU_Cfam_GSD_1.0253,489,618 - 53,497,458 (+)NCBI
CCNB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl569,167,135 - 69,178,245 (+)EnsemblGRCh38hg38GRCh38
GRCh38569,167,150 - 69,178,245 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37568,462,977 - 68,474,072 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36568,498,669 - 68,509,828 (+)NCBINCBI36hg18NCBI36
Build 34568,498,668 - 68,509,824NCBI
Celera565,462,166 - 65,473,328 (+)NCBI
Cytogenetic Map5q13.2NCBI
HuRef565,418,249 - 65,429,485 (+)NCBIHuRef
CHM1_1568,462,558 - 68,473,793 (+)NCBICHM1_1
Ccnb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913100,915,247 - 100,922,994 (-)NCBIGRCm39mm39
GRCm39 Ensembl13100,915,158 - 100,923,078 (-)Ensembl
GRCm3813100,778,739 - 100,786,486 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13100,778,650 - 100,786,570 (-)EnsemblGRCm38mm10GRCm38
MGSCv3713101,548,694 - 101,556,441 (-)NCBIGRCm37mm9NCBIm37
MGSCv3613101,878,996 - 101,886,743 (-)NCBImm8
Celera13104,387,574 - 104,395,322 (-)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1353.23NCBI
Ccnb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2231,912,190 - 31,921,163 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl231,912,193 - 31,921,172 (-)Ensembl
Rnor_6.0230,782,133 - 30,791,106 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl230,783,915 - 30,791,221 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0249,941,586 - 49,948,770 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4231,574,600 - 31,581,784 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1231,493,947 - 31,502,123 (-)NCBI
Celera227,925,441 - 27,934,414 (-)NCBICelera
Cytogenetic Map2q12NCBI
Ccnb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955446140,093 - 149,500 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955446140,661 - 149,500 (-)NCBIChiLan1.0ChiLan1.0
CCNB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1546,394,362 - 46,405,332 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl546,394,362 - 46,405,332 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0544,826,103 - 44,836,832 (-)NCBIMhudiblu_PPA_v0panPan3
Ccnb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213191,463,462 - 191,471,154 (-)NCBI
SpeTri2.0NW_004936480400,287 - 407,677 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCNB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1647,338,110 - 47,348,381 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11647,338,239 - 47,348,385 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21651,155,615 - 51,165,760 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCNB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1465,265,798 - 65,276,465 (+)NCBI
ChlSab1.1 Ensembl465,265,844 - 65,277,085 (+)Ensembl
Vero_WHO_p1.0NW_02366604913,995,123 - 14,005,792 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 3 3 8
Low 2 14 6 3 9 9 3
Below cutoff 5 8 6 6 6 3 1 3

Sequence


Reference Sequences
RefSeq Acc Id: XM_038469964   ⟹   XP_038325892
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1251,827,069 - 51,834,879 (+)NCBI
RefSeq Acc Id: XM_038530772   ⟹   XP_038386700
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0253,489,618 - 53,497,458 (+)NCBI
RefSeq Acc Id: XM_038594994   ⟹   XP_038450922
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0252,602,043 - 52,609,862 (+)NCBI
RefSeq Acc Id: XM_038659070   ⟹   XP_038514998
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0254,767,756 - 54,775,584 (+)NCBI
RefSeq Acc Id: XM_845305   ⟹   XP_850398
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1254,256,957 - 54,264,749 (+)NCBI
Dog10K_Boxer_Tasha251,223,809 - 51,231,591 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038325892 (Get FASTA)   NCBI Sequence Viewer  
  XP_038386700 (Get FASTA)   NCBI Sequence Viewer  
  XP_038450922 (Get FASTA)   NCBI Sequence Viewer  
  XP_038514998 (Get FASTA)   NCBI Sequence Viewer  
  XP_850398 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_850398   ⟸   XM_845305
- UniProtKB: E2R3S2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038325892   ⟸   XM_038469964
RefSeq Acc Id: XP_038450922   ⟸   XM_038594994
RefSeq Acc Id: XP_038514998   ⟸   XM_038659070
RefSeq Acc Id: XP_038386700   ⟸   XM_038530772


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007705 ENTREZGENE
Ensembl Protein ENSCAFP00000030904 ENTREZGENE
NCBI Gene CCNB1 ENTREZGENE
UniProt E2R3S2 ENTREZGENE