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Gene: Ccnb1 (cyclin B1) Mus musculus
Symbol: Ccnb1
Name: cyclin B1
Description: Predicted to have cyclin-dependent protein serine/threonine kinase activator activity; enzyme binding activity; and patched binding activity. Involved in several processes, including histone H3-S10 phosphorylation involved in chromosome condensation; in utero embryonic development; and positive regulation of fibroblast proliferation. Localizes to cytoplasm; membrane; and nucleus. Colocalizes with mitochondrial matrix. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; eye; and genitourinary system. Human ortholog(s) of this gene implicated in breast cancer and prostate cancer. Orthologous to human CCNB1 (cyclin B1); PARTICIPATES IN cell cycle pathway, mitotic; p53 signaling pathway; INTERACTS WITH (S)-nicotine; 1,2-dichloroethane; 1,2-dimethylhydrazine.
Type: protein-coding
Also known as: Ccnb1-rs1; Ccnb1-rs13; Cycb-4; Cycb-5; CycB1; Cycb1-rs1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; MGC18763; MGC90915
Homo sapiens (human) : CCNB1 (cyclin B1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ccnb1 (cyclin B1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccnb1 (cyclin B1)
Pan paniscus (bonobo/pygmy chimpanzee) : CCNB1 (cyclin B1)
Canis lupus familiaris (dog) : CCNB1 (cyclin B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccnb1 (cyclin B1)
Sus scrofa (pig) : CCNB1 (cyclin B1)
Chlorocebus sabaeus (African green monkey) : CCNB1 (cyclin B1)
more info ...
Related Pseudogenes: Gm12856   Gm4870   Gm7067   Gm7483   Gm8416  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl13100,778,650 - 100,786,570 (-)EnsemblGRCm38mm10GRCm38
GRCm3813100,778,739 - 100,786,486 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3713101,548,694 - 101,556,441 (-)NCBIGRCm37mm9NCBIm37
MGSCv3613101,878,996 - 101,886,743 (-)NCBImm8
Celera13104,387,574 - 104,395,322 (-)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1353.23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Ccnb1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735742
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.