Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Vegfc (vascular endothelial growth factor C) Rattus norvegicus
Symbol: Vegfc
Name: vascular endothelial growth factor C
Description: Exhibits vascular endothelial growth factor receptor 3 binding activity. Involved in several processes, including positive regulation of blood vessel endothelial cell migration; positive regulation of cell population proliferation; and positive regulation of protein autophosphorylation. Predicted to localize to extracellular space. Biomarker of colon adenocarcinoma. Human ortholog(s) of this gene implicated in breast carcinoma and hereditary lymphedema ID. Orthologous to human VEGFC (vascular endothelial growth factor C); PARTICIPATES IN vascular endothelial growth factor signaling pathway; ceramide signaling pathway; cytokine mediated signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
Also known as: flt4 ligand; flt4-L; vascular endothelial growth factor-related protein; VEGF-C; VRP
Homo sapiens (human) : VEGFC (vascular endothelial growth factor C)  HGNC  Alliance
Mus musculus (house mouse) : Vegfc (vascular endothelial growth factor C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vegfc (vascular endothelial growth factor C)
Pan paniscus (bonobo/pygmy chimpanzee) : VEGFC (vascular endothelial growth factor C)
Canis lupus familiaris (dog) : VEGFC (vascular endothelial growth factor C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vegfc (vascular endothelial growth factor C)
Sus scrofa (pig) : VEGFC (vascular endothelial growth factor C)
Chlorocebus sabaeus (African green monkey) : VEGFC (vascular endothelial growth factor C)
Heterocephalus glaber (naked mole-rat) : Vegfc (vascular endothelial growth factor C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01640,440,371 - 40,555,178 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1640,440,207 - 40,555,576 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01640,216,307 - 40,331,753 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41640,624,435 - 40,739,692 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11640,624,509 - 40,739,767 (-)NCBI
Celera1635,834,400 - 35,949,683 (-)NCBICelera
Cytogenetic Map16p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Vegfc
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619800
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.