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Gene: Amd1 (adenosylmethionine decarboxylase 1) Rattus norvegicus
Symbol: Amd1
Name: adenosylmethionine decarboxylase 1
Description: Exhibits adenosylmethionine decarboxylase activity and putrescine binding activity. Involved in S-adenosylmethionine metabolic process; spermidine biosynthetic process; and spermine biosynthetic process. Localizes to the cytosol. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human AMD1 (adenosylmethionine decarboxylase 1); PARTICIPATES IN methionine cycle/metabolic pathway; polyamine metabolic pathway; putrescine metabolic pathway; INTERACTS WITH 3H-1,2-dithiole-3-thione; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adoMetDC; Amd1a; Amd1b; S-adenosylmethionine decarboxylase 1; S-Adenosylmethionine decarboxylase 1A; S-Adenosylmethionine decarboxylase 1B; S-adenosylmethionine decarboxylase proenzyme; SAMDC
Homo sapiens (human) : AMD1 (adenosylmethionine decarboxylase 1)  HGNC  Alliance
Mus musculus (house mouse) : Amd1 (S-adenosylmethionine decarboxylase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Amd1 (adenosylmethionine decarboxylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AMD1 (adenosylmethionine decarboxylase 1)
Canis lupus familiaris (dog) : AMD1 (adenosylmethionine decarboxylase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Amd1 (adenosylmethionine decarboxylase 1)
Sus scrofa (pig) : AMD1 (adenosylmethionine decarboxylase 1)
more info ...
Related Pseudogenes: Amd1-ps1   Amd1-ps2   Amd1-ps3  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02045,384,000 - 45,399,694 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02047,103,749 - 47,119,386 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42044,452,475 - 44,468,111 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12044,475,485 - 44,491,122 (-)NCBI
Celera2044,399,688 - 44,415,381 (-)NCBICelera
Cytogenetic Map20q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Amd1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2104
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.