Sgk3 (serum/glucocorticoid regulated kinase family, member 3)

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Gene: Sgk3 (serum/glucocorticoid regulated kinase family, member 3) Rattus norvegicus

Analyze

Symbol:

Sgk3

Name:

serum/glucocorticoid regulated kinase family, member 3

RGD ID:

620242

Description:

Predicted to enable molecular adaptor activity; potassium channel regulator activity; and protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction; localization; and peptidyl-serine phosphorylation. Predicted to act upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in cytoplasmic vesicle and nucleoplasm. Orthologous to several human genes including SGK3 (serum/glucocorticoid regulated kinase family member 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Cuprizon.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Cisk; cytokine-independent survival kinase; LOC103692278; serine/threonine protein kinase CISK; serine/threonine-protein kinase Sgk3; serum/glucocorticoid regulated kinase 3; serum/glucocorticoid regulated kinase-like; serum/glucocorticoid-regulated kinase 3; serum/glucocorticoid-regulated kinase-like; Sgkl; uncharacterized LOC103692278

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	9,345,761 - 9,472,243 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	9,346,040 - 9,415,476 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	11,502,631 - 11,568,922 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	5	13,132,573 - 13,200,616 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	5	12,837,301 - 12,903,595 (-)	NCBI	Rnor_WKY
Rnor_6.0	5	9,046,889 - 9,094,740 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	9,048,614 - 9,094,616 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	13,847,906 - 13,941,451 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	5	8,858,341 - 8,925,021 (-)	NCBI		Celera
Cytogenetic Map	5	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hypotrichosis (ISO)

prostate cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-nitrophenol (ISO)

acrylamide (ISO)

afimoxifene (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

barium(0) (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

choline (ISO)

cisplatin (ISO)

clomiphene (ISO)

cocaine (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

Cuprizon (EXP)

diethylstilbestrol (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

Enterolactone (ISO)

entinostat (ISO)

estrone (ISO)

ethanol (ISO)

folic acid (ISO)

fulvestrant (ISO)

genistein (ISO)

gentamycin (EXP)

glyphosate (ISO)

hexestrol (ISO)

L-methionine (ISO)

mercury dibromide (ISO)

mestranol (ISO)

methamphetamine (ISO)

methyl methanesulfonate (ISO)

nickel dichloride (EXP)

ouabain (ISO)

panobinostat (ISO)

paracetamol (EXP)

paraquat (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

potassium atom (ISO)

progesterone (ISO)

quercetin (ISO)

raloxifene (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

streptozocin (ISO)

testosterone enanthate (ISO)

thapsigargin (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular signal transduction (IBA)

localization (ISO)

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand (IEA,ISO)

peptidyl-serine phosphorylation (IBA)

protein phosphorylation (IEA)

Cellular Component

cytoplasmic vesicle (IEA,ISO)

early endosome (IEA)

intracellular membrane-bounded organelle (ISO)

nucleoplasm (ISO)

recycling endosome (IEA)

Molecular Function

ATP binding (IEA)

molecular adaptor activity (ISO)

phosphatidylinositol binding (IEA)

potassium channel regulator activity (IBA)

protein binding (ISO)

protein serine kinase activity (IEA)

protein serine/threonine kinase activity (IBA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Cloning and mapping of a novel human serum/glucocorticoid regulated kinase-like gene, SGKL, to chromosome 8q12.3-q13.1.	Dai F, etal., Genomics 1999 Nov 15;62(1):95-7.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Information Derived from GenBank Report	RGD, Sept. 2003

Additional References at PubMed

PMID:11050396	PMID:15057822	PMID:23589291	PMID:26823753

Genomics

Comparative Map Data

Sgk3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	9,345,761 - 9,472,243 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	9,346,040 - 9,415,476 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	11,502,631 - 11,568,922 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	5	13,132,573 - 13,200,616 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	5	12,837,301 - 12,903,595 (-)	NCBI	Rnor_WKY
Rnor_6.0	5	9,046,889 - 9,094,740 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	9,048,614 - 9,094,616 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	13,847,906 - 13,941,451 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	5	8,858,341 - 8,925,021 (-)	NCBI		Celera
Cytogenetic Map	5	q11	NCBI

SGK3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	66,712,781 - 66,862,022 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	8	66,712,734 - 66,862,022 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	67,625,016 - 67,774,257 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	67,787,445 - 67,936,811 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	67,850,015 - 67,936,809	NCBI
Celera	8	63,617,793 - 63,767,751 (+)	NCBI		Celera
Cytogenetic Map	8	q13.1	NCBI
HuRef	8	63,116,616 - 63,266,844 (+)	NCBI		HuRef
CHM1_1	8	67,679,569 - 67,829,231 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	67,138,550 - 67,288,509 (+)	NCBI		T2T-CHM13v2.0

Sgk3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	9,868,355 - 9,972,795 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	9,868,332 - 9,971,070 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	9,798,130 - 9,902,570 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	9,798,107 - 9,900,845 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	9,788,211 - 9,892,651 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	9,783,344 - 9,887,784 (+)	NCBI		MGSCv36	mm8
Celera	1	9,770,220 - 9,875,393 (+)	NCBI		Celera
Cytogenetic Map	1	A2	NCBI
cM Map	1	2.08	NCBI

Sgk3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955444	12,385,747 - 12,445,740 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955444	12,385,747 - 12,501,589 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOC100987089
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	8	64,982,973 - 65,067,296 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	64,982,973 - 65,067,296 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	8	63,210,279 - 63,403,991 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

SGK3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	29	16,236,197 - 16,418,225 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	29	16,274,352 - 16,415,598 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	29	16,661,140 - 16,731,156 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	29	16,355,030 - 16,498,290 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	29	16,355,068 - 16,506,875 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	29	16,457,800 - 16,527,880 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	29	16,557,222 - 16,627,460 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	29	16,813,736 - 16,884,005 (+)	NCBI		UU_Cfam_GSD_1.0

Sgk3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	67,520,278 - 67,588,541 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936496	7,195,777 - 7,265,186 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936496	7,196,936 - 7,287,367 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

Sgk3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624744	24,476,626 - 24,539,480 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624744	24,476,880 - 24,613,442 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Sgk3
979 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	90
Count of miRNA genes:	73
Interacting mature miRNAs:	79
Transcripts:	ENSRNOT00000072210
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	1	90450412	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	1	131345958	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	729470	86724018	Rat
2312562	Pur18	Proteinuria QTL 18	2.6	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	5	2138965	32656739	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	2282226	69540447	Rat
2313085	Bss59	Bone structure and strength QTL 59	2.9	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	5	3844018	26141981	Rat
1300117	Hrtrt8	Heart rate QTL 8	3.49		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	3844018	47869213	Rat
61462	Niddm10	Non-insulin dependent diabetes mellitus QTL 10	3.9	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	5	5112159	47171491	Rat
631827	Alc4	Alcohol consumption QTL 4	3.5		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	5	8187501	18616199	Rat
2293666	Bmd38	Bone mineral density QTL 38	4.4		femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	5	8948228	53948228	Rat

Markers in Region

D5Rat215

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	9,359,693 - 9,359,791 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	9,060,224 - 9,060,321	NCBI	Rnor6.0
Rnor_5.0	5	13,861,050 - 13,861,147	UniSTS	Rnor5.0
Celera	5	8,869,263 - 8,869,360	UniSTS
RH 3.4 Map	5	55.5	UniSTS
RH 3.4 Map	5	55.5	RGD
RH 2.0 Map	5	73.6	RGD
SHRSP x BN Map	5	4.56	RGD

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1		21	5	19	5			14	35	28	11
Low	2	43	36	36		36	8	10	60		13		8
Below cutoff								1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001376043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003753981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593903	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109231	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109232	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109233	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF361755	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213720	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000157	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000072210 ⟹ ENSRNOP00000064540

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	9,346,040 - 9,415,476 (-)	Ensembl
Rnor_6.0 Ensembl	5	9,048,614 - 9,094,616 (-)	Ensembl

RefSeq Acc Id:

NM_001376043 ⟹ NP_001362972

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	9,346,040 - 9,415,476 (-)	NCBI

RefSeq Acc Id:

XM_039109231 ⟹ XP_038965159

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	9,345,761 - 9,472,237 (-)	NCBI

RefSeq Acc Id:

XM_039109232 ⟹ XP_038965160

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	9,345,761 - 9,472,237 (-)	NCBI

RefSeq Acc Id:

XM_039109233 ⟹ XP_038965161

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	9,345,761 - 9,472,243 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001362972	(Get FASTA)	NCBI Sequence Viewer
	XP_038965159	(Get FASTA)	NCBI Sequence Viewer
	XP_038965160	(Get FASTA)	NCBI Sequence Viewer
	XP_038965161	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAL91350	(Get FASTA)	NCBI Sequence Viewer
	Q8R4V0	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

ENSRNOP00000064540 ⟸ ENSRNOT00000072210

RefSeq Acc Id:	XP_038965161 ⟸ XM_039109233
- Peptide Label:	isoform X1
- UniProtKB:	M0R582 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038965160 ⟸ XM_039109232
- Peptide Label:	isoform X1
- UniProtKB:	M0R582 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038965159 ⟸ XM_039109231
- Peptide Label:	isoform X1
- UniProtKB:	M0R582 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001362972 ⟸ NM_001376043
- UniProtKB:	M0R582 (UniProtKB/TrEMBL)

Protein Domains

AGC-kinase C-terminal Protein kinase PX

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8R4V0-F1-model_v2	AlphaFold	Q8R4V0	1-496	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620242	AgrOrtholog
BioCyc Gene	G2FUF-42200	BioCyc
Ensembl Genes	ENSRNOG00000049052	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000064540	ENTREZGENE
	ENSRNOP00000064540.3	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000072210	ENTREZGENE
	ENSRNOT00000072210.3	UniProtKB/TrEMBL
Gene3D-CATH	3.30.1520.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	AGC-kinase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CISK_PX	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Phox	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Pkinase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PX_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SGK3_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	171498	ENTREZGENE
Pfam	PF00787	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Pkinase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Pkinase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Sgk3	PhenoGen
PROSITE	AGC_KINASE_CTER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PS50195	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	S_TK_X	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	S_TKc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SM00312	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF64268	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	M0R582	ENTREZGENE, UniProtKB/TrEMBL
	Q8R4V0	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Sgk3	serum/glucocorticoid regulated kinase family, member 3	LOC103692278	uncharacterized LOC103692278	Data Merged	737654	PROVISIONAL
2014-08-25	LOC103692278	uncharacterized LOC103692278			Symbol and Name status set to provisional	70820	PROVISIONAL
2013-08-02	Sgk3	serum/glucocorticoid regulated kinase family, member 3	Sgk3	serum/glucocorticoid regulated kinase 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-11	Sgk3	serum/glucocorticoid regulated kinase 3	Sgk3	serum/glucocorticoid regulated kinase family, member 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-22	Sgk3	serum/glucocorticoid regulated kinase family, member 3	Sgkl	serum/glucocorticoid regulated kinase-like	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Sgkl	serum/glucocorticoid regulated kinase-like		serine/threonine protein kinase CISK	Name updated	1299863	APPROVED
2002-08-07	Sgkl	serine/threonine protein kinase CISK			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIA

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIA