Cracd (capping protein inhibiting regulator of actin dynamics) - Rat Genome Database

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Gene: Cracd (capping protein inhibiting regulator of actin dynamics) Rattus norvegicus
Analyze
Symbol: Cracd
Name: capping protein inhibiting regulator of actin dynamics
RGD ID: 1311575
Description: Predicted to be involved in maintenance of gastrointestinal epithelium and negative regulation of barbed-end actin filament capping. Orthologous to human CRACD (capping protein inhibiting regulator of actin dynamics); INTERACTS WITH 17beta-estradiol; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: MODEL
Also known as: hypothetical LOC289568; LOC289568; RGD1311575; uncharacterized protein KIAA1211 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21431,284,066 - 31,520,103 (-)NCBI
Rnor_6.0 Ensembl1433,649,637 - 33,677,031 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01433,649,989 - 33,783,794 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01433,440,443 - 33,572,091 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41433,579,288 - 33,607,176 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11433,580,497 - 33,603,246 (-)NCBI
Celera1430,598,428 - 30,835,727 (-)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

Additional References at PubMed
PMID:30361697  


Genomics

Comparative Map Data
Cracd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21431,284,066 - 31,520,103 (-)NCBI
Rnor_6.0 Ensembl1433,649,637 - 33,677,031 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01433,649,989 - 33,783,794 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01433,440,443 - 33,572,091 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41433,579,288 - 33,607,176 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11433,580,497 - 33,603,246 (-)NCBI
Celera1430,598,428 - 30,835,727 (-)NCBICelera
Cytogenetic Map14p11NCBI
CRACD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl456,049,073 - 56,328,625 (+)EnsemblGRCh38hg38GRCh38
GRCh38456,049,098 - 56,330,622 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37457,036,361 - 57,196,890 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36456,731,118 - 56,891,647 (+)NCBINCBI36hg18NCBI36
Celera454,542,821 - 54,703,255 (+)NCBI
Cytogenetic Map4q12NCBI
HuRef452,990,321 - 53,150,672 (+)NCBIHuRef
CHM1_1457,071,533 - 57,232,004 (+)NCBICHM1_1
Cracd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39576,803,225 - 77,021,401 (+)NCBIGRCm39mm39
GRCm39 Ensembl576,804,359 - 77,021,401 (+)Ensembl
GRCm38576,657,629 - 76,873,554 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl576,656,512 - 76,873,554 (+)EnsemblGRCm38mm10GRCm38
MGSCv37577,269,624 - 77,302,579 (+)NCBIGRCm37mm9NCBIm37
MGSCv36577,915,374 - 77,948,329 (+)NCBImm8
Celera574,119,956 - 74,149,740 (+)NCBICelera
Cytogenetic Map5C3.3NCBI
Cracd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544714,650,035 - 14,672,593 (-)NCBIChiLan1.0ChiLan1.0
CRACD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1474,167,488 - 74,317,354 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl474,167,488 - 74,199,802 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0467,598,880 - 67,880,269 (-)NCBIMhudiblu_PPA_v0panPan3
Cracd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528527,740,917 - 27,989,201 (-)NCBI
SpeTri2.0NW_00493648218,309,078 - 18,557,335 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRACD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl855,463,441 - 55,600,939 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1855,336,363 - 55,600,931 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2857,919,085 - 57,976,199 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CRACD
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1712,293,366 - 12,570,793 (-)NCBI
ChlSab1.1 Ensembl712,296,214 - 12,325,965 (-)Ensembl
Cracd
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476113,065,318 - 13,367,504 (-)NCBI

Position Markers
RH132249  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21431,284,264 - 31,284,467 (+)MAPPER
Rnor_6.01433,649,731 - 33,649,933NCBIRnor6.0
Rnor_5.01433,440,644 - 33,440,846UniSTSRnor5.0
RGSC_v3.41433,577,884 - 33,578,086UniSTSRGSC3.4
Celera1430,598,170 - 30,598,372UniSTS
RH 3.4 Map14425.9UniSTS
Cytogenetic Map14p11UniSTS
RH141277  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21431,286,266 - 31,286,482 (+)MAPPER
Rnor_6.01433,651,733 - 33,651,948NCBIRnor6.0
Rnor_5.01433,442,646 - 33,442,861UniSTSRnor5.0
RGSC_v3.41433,579,886 - 33,580,101UniSTSRGSC3.4
Celera1430,600,172 - 30,600,387UniSTS
RH 3.4 Map14381.98UniSTS
Cytogenetic Map14p11UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
619619Rf4Renal disease susceptibility QTL 44.10.002total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14134403399Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14141333960Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14141333960Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14142766285Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14975643572854397Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin141053997755539977Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)141053997755539977Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)141072926861873323Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1412680424106641756Rat
631528Scl11Serum cholesterol level QTL 114.9blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)141915991938289187Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)141916189343957503Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141919154143957628Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)142018938665189386Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)142026622343957628Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)142145756566457565Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143259392686191589Rat
2324617Coatc2Coat color QTL 20.001coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)143303991261783215Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143316331673391571Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1222
Count of miRNA genes:319
Interacting mature miRNAs:432
Transcripts:ENSRNOT00000002908, ENSRNOT00000074534
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 8 8 1 8 73 12 24
Low 1 24 33 17 18 17 2 2 1 23 17 11 2
Below cutoff 19 14 14 14 6 8 6

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_006221709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000002908   ⟹   ENSRNOP00000002908
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1433,649,637 - 33,677,031 (-)Ensembl
RefSeq Acc Id: XM_006221709   ⟹   XP_006221771
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1430,598,428 - 30,627,428 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250863   ⟹   XP_006250925
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01433,649,989 - 33,679,158 (-)NCBI
Rnor_5.01433,440,443 - 33,572,091 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765222   ⟹   XP_008763444
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1430,598,428 - 30,627,428 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765226   ⟹   XP_008763448
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1430,598,428 - 30,645,056 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765232   ⟹   XP_008763454
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1430,598,428 - 30,659,401 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765235   ⟹   XP_008763457
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1430,598,428 - 30,634,764 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770114   ⟹   XP_008768336
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01433,649,989 - 33,679,158 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770115   ⟹   XP_008768337
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01433,649,989 - 33,717,863 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770116   ⟹   XP_008768338
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01433,649,989 - 33,783,794 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770117   ⟹   XP_008768339
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01433,649,989 - 33,696,786 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770118   ⟹   XP_008768340
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01433,649,989 - 33,686,495 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599439   ⟹   XP_017454928
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01433,649,989 - 33,678,934 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599440   ⟹   XP_017454929
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01433,649,989 - 33,679,158 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017604774   ⟹   XP_017460263
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1430,598,428 - 30,835,727 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017604775   ⟹   XP_017460264
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1430,598,428 - 30,796,426 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017604776   ⟹   XP_017460265
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1430,598,428 - 30,627,204 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017604777   ⟹   XP_017460266
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1430,598,428 - 30,627,428 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039092919   ⟹   XP_038948847
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21431,284,066 - 31,313,653 (-)NCBI
RefSeq Acc Id: XM_039092920   ⟹   XP_038948848
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21431,284,066 - 31,313,653 (-)NCBI
RefSeq Acc Id: XM_039092921   ⟹   XP_038948849
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21431,284,066 - 31,520,103 (-)NCBI
RefSeq Acc Id: XM_039092922   ⟹   XP_038948850
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21431,284,066 - 31,500,611 (-)NCBI
RefSeq Acc Id: XM_039092923   ⟹   XP_038948851
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21431,284,066 - 31,500,611 (-)NCBI
RefSeq Acc Id: XM_039092924   ⟹   XP_038948852
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21431,284,066 - 31,520,103 (-)NCBI
RefSeq Acc Id: XM_039092925   ⟹   XP_038948853
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21431,284,066 - 31,345,270 (-)NCBI
RefSeq Acc Id: XM_039092926   ⟹   XP_038948854
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21431,284,066 - 31,321,007 (-)NCBI
RefSeq Acc Id: XM_039092927   ⟹   XP_038948855
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21431,284,066 - 31,313,458 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_006221771   ⟸   XM_006221709
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006250925   ⟸   XM_006250863
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008763454   ⟸   XM_008765232
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_008763448   ⟸   XM_008765226
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_008763457   ⟸   XM_008765235
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_008763444   ⟸   XM_008765222
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008768338   ⟸   XM_008770116
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008768337   ⟸   XM_008770115
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008768339   ⟸   XM_008770117
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008768340   ⟸   XM_008770118
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008768336   ⟸   XM_008770114
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017460263   ⟸   XM_017604774
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_017460264   ⟸   XM_017604775
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_017460266   ⟸   XM_017604777
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_017460265   ⟸   XM_017604776
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_017454929   ⟸   XM_017599440
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017454928   ⟸   XM_017599439
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000002908   ⟸   ENSRNOT00000002908
RefSeq Acc Id: XP_038948849   ⟸   XM_039092921
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038948852   ⟸   XM_039092924
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038948851   ⟸   XM_039092923
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038948850   ⟸   XM_039092922
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038948853   ⟸   XM_039092925
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038948854   ⟸   XM_039092926
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038948848   ⟸   XM_039092920
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038948847   ⟸   XM_039092919
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038948855   ⟸   XM_039092927
- Peptide Label: isoform X4
Protein Domains
DUF4592

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
14 33453773 33453774 T G snv ZFDM (KyushuU)
14 33454104 33454105 C T snv IS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311575 AgrOrtholog
Ensembl Genes ENSRNOG00000002139 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000002908 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002908 UniProtKB/TrEMBL
InterPro DUF4592 UniProtKB/TrEMBL
NCBI Gene 289568 ENTREZGENE
Pfam DUF4592 UniProtKB/TrEMBL
PhenoGen Cracd PhenoGen
UniProt D4A5F4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-13 Cracd  capping protein inhibiting regulator of actin dynamics  RGD1311575  hypothetical LOC289568  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1311575  hypothetical LOC289568   RGD1311575_predicted  hypothetical LOC289568 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1311575_predicted  hypothetical LOC289568 (predicted)  LOC289568_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC289568_predicted  hypothetical LOC289568 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL