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Gene: Asah1 (N-acylsphingosine amidohydrolase 1) Rattus norvegicus
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Symbol: Asah1
Name: N-acylsphingosine amidohydrolase 1
Description: Predicted to have N-acylsphingosine amidohydrolase activity; nuclear receptor binding activity; and transcription corepressor activity. Involved in lung development and response to organic substance. Predicted to localize to the extracellular space; lysosome; and nucleus. Human ortholog(s) of this gene implicated in Farber lipogranulomatosis and sphingolipidosis. Orthologous to human ASAH1 (N-acylsphingosine amidohydrolase 1); PARTICIPATES IN ceramide signaling pathway; sphingolipid metabolic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AC; ACDase; acid CDase; acid ceramidase; acylsphingosine deacylase; Asah; N-acylethanolamine hydrolase ASAH1; N-acylsphingosine amidohydrolase (acid ceramidase); N-acylsphingosine amidohydrolase (acid ceramidase) 1
Orthologs:
Homo sapiens (human) : ASAH1 (N-acylsphingosine amidohydrolase 1)  HGNC  Alliance
Mus musculus (house mouse) : Asah1 (N-acylsphingosine amidohydrolase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Asah1 (N-acylsphingosine amidohydrolase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ASAH1 (N-acylsphingosine amidohydrolase 1)
Canis lupus familiaris (dog) : ASAH1 (N-acylsphingosine amidohydrolase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Asah1 (N-acylsphingosine amidohydrolase 1)
Sus scrofa (pig) : ASAH1 (N-acylsphingosine amidohydrolase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01653,998,604 - 54,030,006 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01653,712,315 - 53,743,717 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41654,279,253 - 54,311,084 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11654,279,327 - 54,311,158 (+)NCBI
Celera1648,861,616 - 48,893,051 (+)NCBICelera
Cytogenetic Map16q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Asah1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621568
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.