Ckm (creatine kinase, M-type) - Rat Genome Database
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Gene: Ckm (creatine kinase, M-type) Rattus norvegicus
Analyze
Symbol: Ckm
Name: creatine kinase, M-type
RGD ID: 2358
Description: Exhibits creatine kinase activity. Involved in phosphocreatine biosynthetic process. Predicted to localize to extracellular space. Orthologous to human CKM (creatine kinase, M-type); PARTICIPATES IN creatine metabolic pathway; arginine and proline metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ckmm; CPK-M; creatine kinase M chain; creatine kinase M-type; Creatine kinase muscle form; creatine kinase, muscle; Creatine kinase, muscle form; creatine phosphokinase M-type; M-CK; muscle creatine kinase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2179,061,390 - 79,071,721 (+)NCBI
Rnor_6.0 Ensembl180,321,585 - 80,331,841 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0180,321,507 - 80,331,841 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0181,587,884 - 81,598,112 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,762,202 - 78,772,681 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1178,840,312 - 78,850,792 (+)NCBI
Celera173,523,369 - 73,533,981 (+)NCBICelera
RH 3.4 Map1787.5RGD
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(2,4,5-trichlorophenoxy)acetic acid  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-methyladenine  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
7H-xanthine  (EXP)
9H-xanthine  (EXP)
acrylamide  (EXP)
albuterol  (ISO)
allopurinol  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
apigenin  (EXP)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
C60 fullerene  (EXP)
cadmium dichloride  (ISO)
captan  (ISO)
carbimazole  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
carvacrol  (EXP)
cetirizine  (ISO)
ciguatoxin CTX1B  (ISO)
Citreoviridin  (EXP,ISO)
clarithromycin  (ISO)
cocaine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
crocin-1  (EXP)
curcumin  (EXP)
daunorubicin  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dichloroacetic acid  (ISO)
dichromium trioxide  (ISO)
dioxygen  (ISO)
disodium selenite  (EXP,ISO)
diuron  (EXP)
doxorubicin  (EXP,ISO)
ethanol  (EXP)
etoposide  (ISO)
Fexofenadine hydrochloride  (ISO)
folpet  (ISO)
furan  (EXP)
gallic acid  (EXP)
genistein  (EXP)
gentamycin  (ISO)
graphite  (ISO)
hydrazine  (ISO)
hydrogen peroxide  (EXP)
isoprenaline  (EXP)
isotretinoin  (ISO)
lead diacetate  (EXP,ISO)
lipopolysaccharide  (EXP)
lithium chloride  (ISO)
loperamide  (EXP)
mitoxantrone  (ISO)
N-acetyl-L-cysteine  (EXP)
nickel atom  (ISO)
ozone  (EXP,ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (ISO)
phenytoin  (ISO)
PhIP  (EXP)
pioglitazone  (ISO)
pluronic P-123  (EXP)
Poloxamer  (EXP)
Pristimerin  (EXP)
progesterone  (EXP)
quercetin  (EXP)
ruthenium atom  (EXP)
silicon dioxide  (ISO)
simvastatin  (EXP,ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sodium fluoride  (EXP,ISO)
spermine  (ISO)
tetrachloromethane  (EXP)
tetrathiomolybdate(2-)  (ISO)
thiamine(1+) chloride  (EXP,ISO)
titanium dioxide  (ISO)
triclosan  (ISO)
tunicamycin  (ISO)
vinclozolin  (EXP)
vitamin E  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
extracellular space  (IBA,IEA,ISO,ISS)

Molecular Function
ATP binding  (IEA)
creatine kinase activity  (IBA,IDA,IEA,ISO,TAS)
kinase activity  (IBA)
protein binding  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:6583703   PMID:12968024   PMID:15489334   PMID:15601660   PMID:16107216   PMID:16371353   PMID:16916915   PMID:17153612   PMID:19182904   PMID:21768101   PMID:24177035   PMID:26116865  
PMID:26316108   PMID:29476059  


Genomics

Comparative Map Data
Ckm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2179,061,390 - 79,071,721 (+)NCBI
Rnor_6.0 Ensembl180,321,585 - 80,331,841 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0180,321,507 - 80,331,841 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0181,587,884 - 81,598,112 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,762,202 - 78,772,681 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1178,840,312 - 78,850,792 (+)NCBI
Celera173,523,369 - 73,533,981 (+)NCBICelera
RH 3.4 Map1787.5RGD
Cytogenetic Map1q21NCBI
CKM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1945,306,413 - 45,322,875 (-)EnsemblGRCh38hg38GRCh38
GRCh381945,306,413 - 45,322,875 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371945,809,671 - 45,826,133 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh371945,809,671 - 45,826,302 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,501,511 - 50,517,974 (-)NCBINCBI36hg18NCBI36
Build 341950,501,511 - 50,517,974NCBI
Celera1942,615,239 - 42,631,814 (-)NCBI
Cytogenetic Map19q13.32NCBI
HuRef1942,241,505 - 42,258,552 (-)NCBIHuRef
CHM1_11945,812,972 - 45,829,550 (-)NCBICHM1_1
Ckm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,145,019 - 19,155,508 (+)NCBIGRCm39mm39
GRCm38719,411,094 - 19,421,583 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,404,776 - 19,422,841 (+)EnsemblGRCm38mm10GRCm38
MGSCv37719,996,443 - 20,006,932 (+)NCBIGRCm37mm9NCBIm37
MGSCv36718,569,616 - 18,580,105 (+)NCBImm8
Celera716,817,487 - 16,827,978 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.67NCBI
Ckm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555552,318,072 - 2,336,811 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555552,318,072 - 2,330,733 (-)NCBIChiLan1.0ChiLan1.0
CKM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11950,854,556 - 50,870,366 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1950,854,556 - 50,870,366 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01942,255,158 - 42,271,467 (-)NCBIMhudiblu_PPA_v0panPan3
CKM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1110,210,152 - 110,343,383 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11110,210,158 - 110,218,937 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ckm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049367061,792,298 - 1,801,063 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CKM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl651,699,165 - 51,714,813 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1651,704,021 - 51,716,935 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Pig Cytomap6q22-6q23NCBI
CKM
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,764,229 - 38,778,718 (-)NCBI
ChlSab1.1 Ensembl638,763,402 - 38,776,301 (-)Ensembl
Ckm
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249072,215,260 - 2,226,891 (-)NCBI

Position Markers
D1Kyo1   No map positions available.
PMC125755P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0180,324,950 - 80,325,143NCBIRnor6.0
Rnor_5.0181,591,222 - 81,591,415UniSTSRnor5.0
RGSC_v3.4178,765,540 - 78,765,733UniSTSRGSC3.4
Celera173,526,734 - 73,526,927UniSTS
Cytogenetic Map1q21UniSTS
D1Bda2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0180,331,552 - 80,331,818NCBIRnor6.0
Rnor_5.0181,597,824 - 81,598,090UniSTSRnor5.0
RGSC_v3.4178,772,393 - 78,772,659UniSTSRGSC3.4
Celera173,533,692 - 73,533,958UniSTS
Cytogenetic Map1q21UniSTS
RH94390  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0180,331,733 - 80,331,830NCBIRnor6.0
Rnor_5.0181,598,005 - 81,598,102UniSTSRnor5.0
RGSC_v3.4178,772,574 - 78,772,671UniSTSRGSC3.4
Celera173,533,873 - 73,533,970UniSTS
RH 3.4 Map1787.5UniSTS
Cytogenetic Map5q36UniSTS
Cytogenetic Map1q21UniSTS
RH138712  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0180,331,582 - 80,331,720NCBIRnor6.0
Rnor_5.0181,597,854 - 81,597,992UniSTSRnor5.0
RGSC_v3.4178,772,423 - 78,772,561UniSTSRGSC3.4
Celera173,533,722 - 73,533,860UniSTS
RH 3.4 Map1819.7UniSTS
Cytogenetic Map1q21UniSTS
Ckmm  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0180,324,960 - 80,326,263NCBIRnor6.0
Rnor_5.0181,591,232 - 81,592,535UniSTSRnor5.0
RGSC_v3.4178,765,550 - 78,766,853UniSTSRGSC3.4
Celera173,526,744 - 73,528,047UniSTS
Cytogenetic Map1q21UniSTS
Ckm  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0180,330,112 - 80,331,592NCBIRnor6.0
Rnor_5.0181,596,384 - 81,597,864UniSTSRnor5.0
Cytogenetic Map1q21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)125439386904217Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15655769122614963Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1565577285706974Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)11131448983657083Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11131448983657083Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11131448983657083Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11131448983657083Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11131448983657083Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11131448983657083Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11131448983657083Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123406428108057505Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)125951907130917265Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134993530173445086Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13537750894364229Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)135377692217372257Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13585416780854167Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13585416780854167Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13585416780854167Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14190724986907249Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143579208126240667Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143579208126240667Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143579208126240667Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143579208126240667Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143579208126240667Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)143579208126240667Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143579208126240667Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)149147799156446783Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14954732883657083Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14957857794578577Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149578577169852184Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149578693217054291Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15052271494225616Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)15385134883657083Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15385134883657083Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)157761301104391981Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)158209327103209327Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)158354072161711996Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)164588516125875986Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)166113339122614963Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)16722768394201552Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)179134941113593716Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)179689548124689548Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17968976594909507Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:52
Interacting mature miRNAs:58
Transcripts:ENSRNOT00000022895
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 21 8 11 8
Medium 2 18 8 5 3 5 3 8
Low 1 4 22 9 15 9 8 20 26 3
Below cutoff 7 7 1 7 13 15 8

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_012530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC062058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR458343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN931989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM053193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM056549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M10140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M27092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000022895   ⟹   ENSRNOP00000022895
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl180,321,585 - 80,331,841 (+)Ensembl
RefSeq Acc Id: NM_012530   ⟹   NP_036662
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2179,061,463 - 79,071,721 (+)NCBI
Rnor_6.0180,321,585 - 80,331,841 (+)NCBI
Rnor_5.0181,587,884 - 81,598,112 (+)NCBI
RGSC_v3.4178,762,202 - 78,772,681 (+)RGD
Celera173,523,369 - 73,533,981 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017588776   ⟹   XP_017444265
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2179,061,390 - 79,071,721 (+)NCBI
Rnor_6.0180,321,507 - 80,331,841 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_036662   ⟸   NM_012530
- UniProtKB: P00564 (UniProtKB/Swiss-Prot),   A0A0G2JSP8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444265   ⟸   XM_017588776
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000022895   ⟸   ENSRNOT00000022895
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689772
Promoter ID:EPDNEW_R296
Type:multiple initiation site
Name:Ckm_1
Description:creatine kinase, M-type
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0180,321,609 - 80,321,669EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2358 AgrOrtholog
Ensembl Genes ENSRNOG00000016837 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000022895 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000022895 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.10.135.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5598226 IMAGE-MGC_LOAD
InterPro ATP-guanido_PTrfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-guanido_PTrfase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-guanido_PTrfase_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-guanido_PTrfase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-guanido_PTrfase_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gln_synth/guanido_kin_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72543 IMAGE-MGC_LOAD
NCBI Gene 24265 ENTREZGENE
PANTHER PTHR11547 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ATP-gua_Ptrans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-gua_PtransN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ckm PhenoGen
PROSITE PHOSPHAGEN_KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHOSPHAGEN_KINASE_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHOSPHAGEN_KINASE_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48034 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55931 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC228777
UniProt A0A0G2JSP8 ENTREZGENE, UniProtKB/TrEMBL
  KCRM_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q6P6R9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-17 Ckm  creatine kinase, M-type  Ckm  creatine kinase, muscle  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-11-06 Ckm  creatine kinase, muscle    Creatine kinase, muscle form  Name updated 625702 APPROVED
2002-06-10 Ckm  Creatine kinase, muscle form      Symbol and Name status set to approved 70586 APPROVED