(-)-demecolcine increases expression ISO RGD:1316757 6480464 Demecolcine results in increased expression of SESN1 mRNA CTD PMID:23649840 (S)-colchicine increases expression EXP 6480464 Colchicine results in increased expression of SESN1 mRNA CTD PMID:20624997 (S)-colchicine decreases expression ISO RGD:1316757 6480464 Colchicine results in decreased expression of SESN1 mRNA CTD PMID:24211769 17alpha-ethynylestradiol affects expression ISO RGD:1316758 6480464 Ethinyl Estradiol affects the expression of SESN1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol increases expression ISO RGD:1316758 6480464 Ethinyl Estradiol results in increased expression of SESN1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol multiple interactions ISO RGD:1316758 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SESN1 mRNA CTD PMID:17942748 17beta-estradiol affects expression ISO RGD:1316757 6480464 Estradiol affects the expression of SESN1 mRNA CTD PMID:22574217 17beta-estradiol decreases expression ISO RGD:1316757 6480464 Estradiol results in decreased expression of SESN1 mRNA CTD PMID:31614463 17beta-estradiol multiple interactions ISO RGD:1316757 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of SESN1 mRNA CTD PMID:30165855 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO RGD:1316757 6480464 AR protein affects the reaction [Metribolone results in decreased expression of SESN1 protein] CTD PMID:16751804 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one decreases expression ISO RGD:1316757 6480464 Metribolone results in decreased expression of SESN1 mRNA, Metribolone results in decreased expression of SESN1 protein CTD PMID:16751804 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1316758 6480464 [Tetrachlorodibenzodioxin affects the methylation of SESN1 intron] which results in decreased expression of SESN1 mRNA, [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SESN1 mRNA CTD PMID:17942748 , PMID:33017471 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of SESN1 mRNA CTD PMID:21724226 , PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1316758 6480464 Tetrachlorodibenzodioxin affects the expression of SESN1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1316757 6480464 Tetrachlorodibenzodioxin results in decreased expression of SESN1 mRNA CTD PMID:20106945 , PMID:21632981 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of SESN1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1316758 6480464 Tetrachlorodibenzodioxin results in decreased expression of SESN1 mRNA CTD PMID:19770486 2-methoxyethanol increases expression EXP 6480464 methyl cellosolve results in increased expression of SESN1 mRNA CTD PMID:21061450 4-hydroxyphenyl retinamide decreases expression ISO RGD:1316758 6480464 Fenretinide results in decreased expression of SESN1 mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine affects expression ISO RGD:1316757 6480464 Decitabine affects the expression of SESN1 mRNA CTD PMID:23300844 5-fluorouracil multiple interactions ISO RGD:1316757 6480464 TP53 protein affects the reaction [Fluorouracil results in increased expression of SESN1 mRNA], TP53 protein promotes the reaction [Fluorouracil results in increased expression of SESN1 mRNA] CTD PMID:15016801 , PMID:17982676 5-fluorouracil increases expression ISO RGD:1316757 6480464 Fluorouracil results in increased expression of SESN1 mRNA, Fluorouracil results in increased expression of SESN1 protein CTD PMID:14665630 more ... acrylamide affects expression EXP 6480464 Acrylamide affects the expression of SESN1 mRNA CTD PMID:28959563 adefovir pivoxil increases expression ISO RGD:1316757 6480464 adefovir dipivoxil results in increased expression of SESN1 mRNA CTD PMID:25596134 adenine decreases expression ISO RGD:1316757 6480464 Adenine results in decreased expression of SESN1 mRNA CTD PMID:24211769 afimoxifene multiple interactions ISO RGD:1316757 6480464 afimoxifene inhibits the reaction [Estrogens results in decreased expression of SESN1 mRNA] CTD PMID:21233418 aflatoxin B1 affects expression ISO RGD:1316757 6480464 Aflatoxin B1 affects the expression of SESN1 protein CTD PMID:20106945 aflatoxin B1 increases expression ISO RGD:1316757 6480464 Aflatoxin B1 results in increased expression of SESN1 mRNA CTD PMID:21632981 more ... amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of SESN1 mRNA CTD PMID:30779732 arsenous acid increases expression ISO RGD:1316757 6480464 Arsenic Trioxide results in increased expression of SESN1 mRNA CTD PMID:22521957 benzo[a]pyrene affects expression ISO RGD:1316757 6480464 Benzo(a)pyrene affects the expression of SESN1 mRNA CTD PMID:21873647 benzo[a]pyrene increases expression ISO RGD:1316757 6480464 Benzo(a)pyrene results in increased expression of SESN1 mRNA CTD PMID:20064835 more ... benzo[a]pyrene decreases expression ISO RGD:1316758 6480464 Benzo(a)pyrene results in decreased expression of SESN1 mRNA CTD PMID:19770486 benzo[a]pyrene diol epoxide I increases expression ISO RGD:1316757 6480464 7 more ... CTD PMID:20382639 , PMID:26238291 bilirubin IXalpha decreases expression ISO RGD:1316757 6480464 Bilirubin results in decreased expression of SESN1 mRNA CTD PMID:20196124 bis(2-chloroethyl) sulfide increases expression ISO RGD:1316757 6480464 Mustard Gas results in increased expression of SESN1 mRNA CTD PMID:25102026 bisphenol A decreases expression ISO RGD:1316758 6480464 bisphenol A results in decreased expression of SESN1 mRNA CTD PMID:26063408 bisphenol A decreases expression ISO RGD:1316757 6480464 bisphenol A analog results in decreased expression of SESN1 mRNA CTD PMID:32387340 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SESN1 mRNA CTD PMID:30816183 , PMID:32528016 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SESN1 mRNA CTD PMID:25181051 Brusatol multiple interactions ISO RGD:1316757 6480464 brusatol inhibits the reaction [Saponins inhibits the reaction [Hydrogen Peroxide results in decreased expression of SESN1 mRNA]] CTD PMID:29274434 cadmium dichloride decreases expression ISO RGD:1316757 6480464 Cadmium Chloride results in decreased expression of SESN1 mRNA CTD PMID:25596134 calcitriol multiple interactions ISO RGD:1316757 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of SESN1 mRNA CTD PMID:21592394 calcitriol decreases expression ISO RGD:1316757 6480464 Calcitriol results in decreased expression of SESN1 mRNA CTD PMID:21592394 carbamazepine affects expression ISO RGD:1316757 6480464 Carbamazepine affects the expression of SESN1 mRNA CTD PMID:25979313 carbon nanotube decreases expression ISO RGD:1316758 6480464 Nanotubes more ... CTD PMID:25554681 , PMID:25620056 celastrol decreases expression ISO RGD:1316757 6480464 celastrol results in decreased expression of SESN1 mRNA CTD PMID:17010675 chloroacetaldehyde increases expression ISO RGD:1316757 6480464 chloroacetaldehyde results in increased expression of SESN1 mRNA CTD PMID:25596134 chlorpromazine decreases expression EXP 6480464 Chlorpromazine results in decreased expression of SESN1 mRNA CTD PMID:25596134 cidofovir anhydrous increases expression ISO RGD:1316757 6480464 Cidofovir results in increased expression of SESN1 mRNA CTD PMID:25596134 cisplatin multiple interactions ISO RGD:1316757 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of SESN1 mRNA, [Piroxicam co-treated with Cisplatin] results in decreased expression of SESN1 mRNA CTD PMID:21858171 , PMID:27392435 cisplatin increases expression ISO RGD:1316757 6480464 Cisplatin results in increased expression of SESN1 mRNA CTD PMID:19561079 more ... cisplatin affects expression ISO RGD:1316757 6480464 Cisplatin affects the expression of SESN1 mRNA CTD PMID:23300844 cobalt dichloride increases expression ISO RGD:1316757 6480464 cobaltous chloride results in increased expression of SESN1 mRNA CTD PMID:19376846 colforsin daropate hydrochloride decreases expression ISO RGD:1316757 6480464 Colforsin results in decreased expression of SESN1 mRNA, Colforsin results in decreased expression of SESN1 protein CTD PMID:16751804 colforsin daropate hydrochloride multiple interactions ISO RGD:1316757 6480464 AR protein affects the reaction [Colforsin results in decreased expression of SESN1 protein] CTD PMID:16751804 copper(II) sulfate decreases expression ISO RGD:1316757 6480464 Copper Sulfate results in decreased expression of SESN1 mRNA CTD PMID:19549813 cyclosporin A decreases expression ISO RGD:1316758 6480464 Cyclosporine results in decreased expression of SESN1 mRNA CTD PMID:19770486 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of SESN1 mRNA CTD PMID:25596134 cyclosporin A affects expression ISO RGD:1316757 6480464 Cyclosporine affects the expression of SESN1 mRNA CTD PMID:25596134 cyclosporin A decreases expression ISO RGD:1316757 6480464 Cyclosporine results in decreased expression of SESN1 mRNA CTD PMID:25562108 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of SESN1 mRNA CTD PMID:20032058 dexamethasone increases expression ISO RGD:1316758 6480464 Dexamethasone results in increased expression of SESN1, Dexamethasone results in increased expression of SESN1 mRNA CTD PMID:22733784 , PMID:33567340 dexamethasone multiple interactions EXP 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of SESN1 mRNA] CTD PMID:20032058 diarsenic trioxide increases expression ISO RGD:1316757 6480464 Arsenic Trioxide results in increased expression of SESN1 mRNA CTD PMID:22521957 dicrotophos decreases expression ISO RGD:1316757 6480464 dicrotophos results in decreased expression of SESN1 mRNA CTD PMID:28302478 dioxygen decreases expression ISO RGD:1316757 6480464 Oxygen deficiency results in decreased expression of SESN1 mRNA CTD PMID:25596134 dioxygen multiple interactions ISO RGD:1316758 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of SESN1 mRNA CTD PMID:30529165 disodium selenite increases expression ISO RGD:1316757 6480464 Sodium Selenite results in increased expression of SESN1 mRNA CTD PMID:24383545 diuron increases expression EXP 6480464 Diuron results in increased expression of SESN1 mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO RGD:1316757 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SESN1 mRNA CTD PMID:27188386 doxorubicin affects expression ISO RGD:1316757 6480464 Doxorubicin affects the expression of SESN1 mRNA CTD PMID:25529476 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of SESN1 mRNA CTD PMID:29391264 erastin multiple interactions ISO RGD:1316757 6480464 SESN1 protein inhibits the reaction [erastin results in decreased expression of GPX4 protein] CTD PMID:31323261 ethyl methanesulfonate increases expression ISO RGD:1316757 6480464 Ethyl Methanesulfonate results in increased expression of SESN1 mRNA CTD PMID:23649840 etoposide increases expression ISO RGD:1316757 6480464 Etoposide results in increased expression of SESN1 mRNA CTD PMID:24211769 fenofibrate decreases expression EXP 6480464 Fenofibrate results in decreased expression of SESN1 mRNA CTD PMID:25596134 fluoranthene multiple interactions ISO RGD:1316758 6480464 [1-methylanthracene co-treated with fluoranthene] results in decreased expression of SESN1 mRNA CTD PMID:28329830 folpet decreases expression ISO RGD:1316758 6480464 folpet results in decreased expression of SESN1 mRNA CTD PMID:31558096 formaldehyde decreases expression ISO RGD:1316757 6480464 Formaldehyde results in decreased expression of SESN1 mRNA CTD PMID:20655997 formaldehyde increases expression ISO RGD:1316757 6480464 Formaldehyde results in increased expression of SESN1 mRNA CTD PMID:23649840 gedunin decreases expression ISO RGD:1316757 6480464 gedunin results in decreased expression of SESN1 mRNA CTD PMID:17010675 genistein increases expression ISO RGD:1316757 6480464 Genistein results in increased expression of SESN1 mRNA CTD PMID:18847459 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of SESN1 mRNA CTD PMID:22061828 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of SESN1 mRNA CTD PMID:33387578 hydrogen peroxide affects expression ISO RGD:1316757 6480464 Hydrogen Peroxide affects the expression of SESN1 mRNA CTD PMID:20044591 hydrogen peroxide decreases expression ISO RGD:1316757 6480464 Hydrogen Peroxide results in decreased expression of SESN1 mRNA CTD PMID:29274434 hydrogen peroxide multiple interactions ISO RGD:1316757 6480464 brusatol inhibits the reaction [Saponins inhibits the reaction [Hydrogen Peroxide results in decreased expression of SESN1 mRNA]], Saponins inhibits the reaction [Hydrogen Peroxide results in decreased expression of SESN1 mRNA] CTD PMID:29274434 hydroquinone increases expression ISO RGD:1316757 6480464 hydroquinone results in increased expression of SESN1 mRNA CTD PMID:23416264 hydroxyurea increases expression ISO RGD:1316757 6480464 Hydroxyurea results in increased expression of SESN1 mRNA CTD PMID:24211769 ibuprofen decreases expression EXP 6480464 Ibuprofen results in decreased expression of SESN1 mRNA CTD PMID:25596134 ifosfamide increases expression ISO RGD:1316757 6480464 Ifosfamide results in increased expression of SESN1 mRNA CTD PMID:25596134 isoflavones increases expression ISO RGD:1316757 6480464 Isoflavones results in increased expression of SESN1 mRNA CTD PMID:17374662 isoprenaline increases expression ISO RGD:1316758 6480464 Isoproterenol results in increased expression of SESN1 mRNA CTD PMID:20003209 ketamine increases expression EXP 6480464 Ketamine results in increased expression of SESN1 mRNA CTD PMID:20080153 leflunomide decreases expression ISO RGD:1316757 6480464 leflunomide results in decreased expression of SESN1 mRNA CTD PMID:28988120 leptomycin B increases expression ISO RGD:1316757 6480464 leptomycin B results in increased expression of SESN1 mRNA CTD PMID:20803015 lipopolysaccharide decreases expression ISO RGD:1316758 6480464 Lipopolysaccharides results in decreased expression of SESN1 mRNA CTD PMID:26582142 mercury dibromide increases expression ISO RGD:1316757 6480464 mercuric bromide results in increased expression of SESN1 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:1316757 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SESN1 mRNA CTD PMID:27188386 mercury dichloride decreases expression EXP 6480464 Mercuric Chloride results in decreased expression of SESN1 mRNA CTD PMID:16507785 metformin decreases expression EXP 6480464 Metformin results in decreased expression of SESN1 mRNA CTD PMID:25596134 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of SESN1 mRNA CTD PMID:30467583 methyl methanesulfonate increases expression ISO RGD:1316757 6480464 Methyl Methanesulfonate results in increased expression of SESN1 mRNA CTD PMID:23649840 methylisothiazolinone increases expression ISO RGD:1316757 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of SESN1 mRNA CTD PMID:31629900 myristicin decreases expression ISO RGD:1316757 6480464 myristicin results in decreased expression of SESN1 mRNA CTD PMID:24792648 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine decreases expression ISO RGD:1316757 6480464 N more ... CTD PMID:12756304 N-nitrosodiethylamine multiple interactions ISO RGD:1316758 6480464 [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of SESN1 gene CTD PMID:23968726 nickel atom decreases expression ISO RGD:1316757 6480464 Nickel results in decreased expression of SESN1 mRNA CTD PMID:24768652 , PMID:25583101 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of SESN1 mRNA CTD PMID:22546817 ozone decreases expression ISO RGD:1316758 6480464 Ozone results in decreased expression of SESN1 mRNA CTD PMID:12763052 paracetamol affects expression ISO RGD:1316758 6480464 Acetaminophen affects the expression of SESN1 mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of SESN1 mRNA CTD PMID:33387578 paracetamol increases expression ISO RGD:1316757 6480464 Acetaminophen results in increased expression of SESN1 mRNA CTD PMID:21420995 , PMID:22230336 paraquat increases expression ISO RGD:1316758 6480464 Paraquat results in increased expression of SESN1 mRNA CTD PMID:12595580 phenobarbital increases expression ISO RGD:1316758 6480464 Phenobarbital results in increased expression of SESN1 mRNA CTD PMID:19270015 picoxystrobin increases expression ISO RGD:1316757 6480464 picoxystrobin results in increased expression of SESN1 mRNA CTD PMID:33512557 piperonyl butoxide multiple interactions ISO RGD:1316758 6480464 [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of SESN1 gene CTD PMID:23968726 pirinixic acid multiple interactions ISO RGD:1316758 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SESN1 mRNA CTD PMID:19710929 piroxicam multiple interactions ISO RGD:1316757 6480464 [Piroxicam co-treated with Cisplatin] results in decreased expression of SESN1 mRNA CTD PMID:21858171 potassium bromate increases expression ISO RGD:1316757 6480464 potassium bromate results in increased expression of SESN1 mRNA CTD PMID:30559759 propanal increases expression ISO RGD:1316757 6480464 propionaldehyde results in increased expression of SESN1 mRNA CTD PMID:26079696 Ptaquiloside increases expression ISO RGD:1316757 6480464 ptaquiloside results in increased expression of SESN1 mRNA CTD PMID:22143989 quercetin increases expression ISO RGD:1316757 6480464 Quercetin results in increased expression of SESN1 mRNA CTD PMID:21632981 resveratrol increases expression ISO RGD:1316757 6480464 resveratrol results in increased expression of SESN1 mRNA CTD PMID:15767336 SB 431542 multiple interactions ISO RGD:1316757 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SESN1 mRNA CTD PMID:27188386 silicon dioxide decreases expression ISO RGD:1316758 6480464 Silicon Dioxide results in decreased expression of SESN1 mRNA CTD PMID:19073995 silver atom decreases expression ISO RGD:1316757 6480464 Silver results in decreased expression of SESN1 mRNA CTD PMID:26014281 silver(0) decreases expression ISO RGD:1316757 6480464 Silver results in decreased expression of SESN1 mRNA CTD PMID:26014281 sodium arsenite multiple interactions ISO RGD:1316757 6480464 pifithrin inhibits the reaction [sodium arsenite results in increased expression of SESN1 mRNA], sodium arsenite promotes the reaction [TP53 protein binds to SESN1 promoter] CTD PMID:26148435 sodium arsenite affects methylation ISO RGD:1316757 6480464 sodium arsenite affects the methylation of SESN1 gene CTD PMID:28589171 sodium arsenite increases expression ISO RGD:1316757 6480464 sodium arsenite results in increased expression of SESN1 mRNA CTD PMID:26148435 succimer multiple interactions ISO RGD:1316758 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of SESN1 mRNA CTD PMID:21641980 sunitinib increases expression ISO RGD:1316757 6480464 Sunitinib results in increased expression of SESN1 mRNA CTD PMID:31533062 tamoxifen affects expression ISO RGD:1316758 6480464 Tamoxifen affects the expression of SESN1 mRNA CTD PMID:17555576 testosterone decreases expression ISO RGD:1316757 6480464 Testosterone results in decreased expression of SESN1 mRNA CTD PMID:21592394 testosterone multiple interactions EXP 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of SESN1 mRNA] CTD PMID:20032058 testosterone multiple interactions ISO RGD:1316757 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of SESN1 mRNA CTD PMID:21592394 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of SESN1 mRNA CTD PMID:31150632 tetrachloromethane decreases expression ISO RGD:1316758 6480464 Carbon Tetrachloride results in decreased expression of SESN1 mRNA CTD PMID:31919559 tremolite asbestos decreases expression ISO RGD:1316758 6480464 tremolite results in decreased expression of SESN1 mRNA CTD PMID:29279043 triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of SESN1 mRNA CTD PMID:30589522 troglitazone decreases expression ISO RGD:1316758 6480464 troglitazone results in decreased expression of SESN1 mRNA CTD PMID:17569031 , PMID:28973697 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of SESN1 mRNA CTD PMID:25596134 tungsten increases expression ISO RGD:1316758 6480464 Tungsten results in increased expression of SESN1 mRNA CTD PMID:30912803 valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of SESN1 mRNA CTD PMID:24136188 valproic acid decreases methylation ISO RGD:1316757 6480464 Valproic Acid results in decreased methylation of SESN1 gene CTD PMID:29154799 valproic acid affects expression ISO RGD:1316757 6480464 Valproic Acid affects the expression of SESN1 mRNA CTD PMID:25979313 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of SESN1 mRNA CTD PMID:22570695 vincristine increases expression EXP 6480464 Vincristine results in increased expression of SESN1 mRNA CTD PMID:20624997 zoledronic acid decreases expression ISO RGD:1316757 6480464 zoledronic acid results in decreased expression of SESN1 mRNA CTD PMID:25596134