Gene: Tff3 (trefoil factor 3) Rattus norvegicus
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Symbol: Tff3
Name: trefoil factor 3
Description: INVOLVED IN response to peptide hormone; regulation of glucose metabolic process (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH colon cancer; Fetal Growth Retardation; pre-malignant neoplasm; FOUND IN extracellular region (ortholog); secretory granule (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol
AGR Description: Involved in response to peptide hormone; predicted to localize to the extracellular space and secretory granule; biomarker of colon cancer and pre-malignant neoplasm; orthologous to human TFF3 (trefoil factor 3).
Merged Description: Involved in response to peptide hormone; predicted to localize to the extracellular space and secretory granule; biomarker of colon cancer and pre-malignant neoplasm; orthologous to human TFF3 (trefoil factor 3); PARTICIPATES IN hypoxia inducible factor pathway; interleukin-4 signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: intestinal trefoil factor; ITF; polypeptide P1.B; rITF; rP1.B; TREFOIL; Trefoil factor (intestinal); trefoil factor 3, intestinal
Orthologs:
Homo sapiens (human) : TFF3 (trefoil factor 3)  HGNC  Alliance
Mus musculus (house mouse) : Tff3 (trefoil factor 3, intestinal)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tff3 (trefoil factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TFF3 (trefoil factor 3)
Canis lupus familiaris (dog) : TFF3 (trefoil factor 3)
Sus scrofa (pig) : TFF3 (trefoil factor 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0209,850,800 - 9,855,481 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02012,030,957 - 12,035,638 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4209,469,888 - 9,474,604 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1209,470,114 - 9,474,831 (-)NCBI
Celera2010,718,676 - 10,723,298 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tff3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3847
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.