TFF3 (trefoil factor 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: TFF3 (trefoil factor 3) Pan paniscus
Analyze
Symbol: TFF3
Name: trefoil factor 3
RGD ID: 11908540
Description: ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN response to peptide hormone (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Animal Hepatitis (ortholog); cataract 9 multiple types (ortholog); FOUND IN cytoplasm (inferred); extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22238,375,036 - 38,379,891 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12133,229,675 - 33,234,530 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02128,627,191 - 28,631,341 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12141,948,674 - 41,952,207 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2141,948,696 - 41,952,268 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TFF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22238,375,036 - 38,379,891 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12133,229,675 - 33,234,530 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02128,627,191 - 28,631,341 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12141,948,674 - 41,952,207 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2141,948,696 - 41,952,268 (-)Ensemblpanpan1.1panPan2
TFF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382142,311,667 - 42,315,409 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2142,311,667 - 42,315,409 (-)EnsemblGRCh38hg38GRCh38
GRCh372143,731,777 - 43,735,519 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362142,605,232 - 42,608,775 (-)NCBINCBI36Build 36hg18NCBI36
Build 342142,605,232 - 42,608,775NCBI
Celera2128,880,742 - 28,884,671 (-)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2129,149,059 - 29,152,988 (-)NCBIHuRef
CHM1_12143,291,988 - 43,295,917 (-)NCBICHM1_1
T2T-CHM13v2.02140,701,121 - 40,704,863 (-)NCBIT2T-CHM13v2.0
Tff3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391731,344,280 - 31,348,585 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1731,344,280 - 31,348,620 (-)EnsemblGRCm39 Ensembl
GRCm381731,125,306 - 31,129,611 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1731,125,306 - 31,129,646 (-)EnsemblGRCm38mm10GRCm38
MGSCv371731,262,251 - 31,266,556 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361730,852,327 - 30,856,623 (-)NCBIMGSCv36mm8
Celera1732,042,584 - 32,046,915 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1715.8NCBI
Tff3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8209,194,623 - 9,199,333 (-)NCBIGRCr8
mRatBN7.2209,193,259 - 9,197,969 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl209,193,262 - 9,198,054 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx209,888,414 - 9,893,424 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0209,249,594 - 9,254,604 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0209,724,117 - 9,728,984 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0209,850,800 - 9,855,481 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl209,850,803 - 9,855,481 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02012,030,957 - 12,035,638 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4209,469,888 - 9,474,604 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1209,470,114 - 9,474,831 (-)NCBI
Celera2010,718,676 - 10,723,298 (-)NCBICelera
Cytogenetic Map20p12NCBI
Tff3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540739,398,074 - 39,401,248 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540739,398,534 - 39,401,085 (+)NCBIChiLan1.0ChiLan1.0
TFF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13136,638,762 - 36,641,696 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3135,789,681 - 35,792,613 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03136,155,220 - 36,158,156 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3136,155,093 - 36,158,196 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13136,048,305 - 36,051,229 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03136,028,347 - 36,031,279 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03136,523,422 - 36,526,353 (-)NCBIUU_Cfam_GSD_1.0
TFF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13205,641,038 - 205,644,333 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113205,641,038 - 205,644,333 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213216,043,521 - 216,046,817 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003823887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000036779   ⟹   ENSPPAP00000014103
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2141,948,696 - 41,952,268 (-)Ensembl
RefSeq Acc Id: XM_003823887   ⟹   XP_003823935
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22238,375,036 - 38,379,891 (-)NCBI
NHGRI_mPanPan12133,229,675 - 33,234,530 (-)NCBI
Mhudiblu_PPA_v02128,627,191 - 28,631,341 (-)NCBI
PanPan1.12141,948,674 - 41,952,207 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003823935 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000014103.1
Reference Protein Sequences
RefSeq Acc Id: XP_003823935   ⟸   XM_003823887
- Sequence:
RefSeq Acc Id: ENSPPAP00000014103   ⟸   ENSPPAT00000036779
Protein Domains
P-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030214 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000036779.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.110.10 UniProtKB/TrEMBL
InterPro P_trefoil_chordata UniProtKB/TrEMBL
  P_trefoil_CS UniProtKB/TrEMBL
  P_trefoil_dom UniProtKB/TrEMBL
  P_trefoil_dom_sf UniProtKB/TrEMBL
NCBI Gene TFF3 ENTREZGENE
PANTHER PTHR13826 UniProtKB/TrEMBL
  TREFOIL FACTOR 3 UniProtKB/TrEMBL
Pfam Trefoil UniProtKB/TrEMBL
PRINTS PTREFOIL UniProtKB/TrEMBL
PROSITE P_TREFOIL_1 UniProtKB/TrEMBL
  P_TREFOIL_2 UniProtKB/TrEMBL
SMART SM00018 UniProtKB/TrEMBL
Superfamily-SCOP SSF57492 UniProtKB/TrEMBL
UniProt A0A2R9AEZ5_PANPA UniProtKB/TrEMBL