Gene: Txnip (thioredoxin interacting protein) Rattus norvegicus
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Symbol: Txnip
Name: thioredoxin interacting protein
Description: ENCODES a protein that exhibits enzyme inhibitor activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN positive regulation of apoptotic process; regulation of cell proliferation; response to calcium ion; ASSOCIATED WITH Colorectal Neoplasms; Diabetes Mellitus, Experimental ; glaucoma; FOUND IN cytoplasm; mitochondrial intermembrane space; nucleus; INTERACTS WITH 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC94673; thioredoxin-interacting protein; upregulated by 1,25-dihydroxyvitamin D-3; Vdup1; vitamin D3 up-regulated protein 1
Orthologs:
Homo sapiens (human) : TXNIP (thioredoxin interacting protein)  HGNC  Alliance
Mus musculus (house mouse) : Txnip (thioredoxin interacting protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Txnip (thioredoxin interacting protein)
Pan paniscus (bonobo/pygmy chimpanzee) : TXNIP (thioredoxin interacting protein)
Canis lupus familiaris (dog) : TXNIP (thioredoxin interacting protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Txnip (thioredoxin interacting protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02198,683,168 - 198,686,971 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02218,170,102 - 218,173,905 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42191,356,954 - 191,360,757 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12191,319,631 - 191,323,506 (+)NCBI
Celera2176,618,301 - 176,622,104 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Txnip
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620886
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-10-09
Status: ACTIVE