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Gene: Arx (aristaless related homeobox) Rattus norvegicus
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Symbol: Arx
Name: aristaless related homeobox
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II distal enhancer sequence-specific DNA binding activity; and chromatin binding activity. Involved in brain development and neuron development. Localizes to the nucleus. Biomarker of type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Partington syndrome; early infantile epileptic encephalopathy 1; lissencephaly; non-syndromic X-linked intellectual disability; and syndromic X-linked intellectual disability Hedera type. Orthologous to human ARX (aristaless related homeobox); INTERACTS WITH 6-propyl-2-thiouracil; dibutyl phthalate; gentamycin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: aristaless related homeobox gene (Drosophila); aristaless-related homeobox; homeobox protein ARX; LOC317268; RGD1562672; similar to Arx homeoprotein
Orthologs:
Homo sapiens (human) : ARX (aristaless related homeobox)  HGNC  Alliance
Mus musculus (house mouse) : Arx (aristaless related homeobox)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arx (aristaless related homeobox)
Pan paniscus (bonobo/pygmy chimpanzee) : ARX (aristaless related homeobox)
Canis lupus familiaris (dog) : ARX (aristaless related homeobox)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arx (aristaless related homeobox)
Sus scrofa (pig) : ARX (aristaless related homeobox)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X62,363,757 - 62,376,139 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX62,363,757 - 62,376,143 (+)Ensembl
Rnor_5.0X62,957,562 - 62,969,944 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X80,631,375 - 80,643,989 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX58,455,664 - 58,467,636 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Arx
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1562672
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.