(+)-catechin multiple interactions ISO RGD:731763 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of LIG1 mRNA CTD PMID:24763279 1,1-dichloroethene increases expression ISO RGD:731764 6480464 vinylidene chloride results in increased expression of LIG1 mRNA CTD PMID:26682919 1,2-dimethylhydrazine multiple interactions ISO RGD:731764 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of LIG1 mRNA CTD PMID:22206623 1-chloro-2,4-dinitrobenzene increases expression ISO RGD:731764 6480464 Dinitrochlorobenzene results in increased expression of LIG1 mRNA CTD PMID:21404309 17alpha-ethynylestradiol affects expression ISO RGD:731764 6480464 Ethinyl Estradiol affects the expression of LIG1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol multiple interactions ISO RGD:731764 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LIG1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO RGD:731764 6480464 Ethinyl Estradiol results in increased expression of LIG1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:731764 6480464 Tetrachlorodibenzodioxin affects the expression of LIG1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of LIG1 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:731764 6480464 Tetrachlorodibenzodioxin results in decreased expression of LIG1 mRNA CTD PMID:15034205 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:731764 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LIG1 mRNA, AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of LIG1 mRNA] CTD PMID:15034205 , PMID:17942748 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:23196670 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:731763 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of LIG1 mRNA CTD PMID:28628672 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression ISO RGD:731764 6480464 Oxazolone results in increased expression of LIG1 mRNA CTD PMID:21404309 4-hydroxyphenyl retinamide increases expression ISO RGD:731764 6480464 Fenretinide results in increased expression of LIG1 mRNA CTD PMID:28973697 5-fluorouracil affects response to substance ISO RGD:731763 6480464 LIG1 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 acetamide increases expression EXP 6480464 acetamide results in increased expression of LIG1 mRNA CTD PMID:31881176 acrolein multiple interactions ISO RGD:731763 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of LIG1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of LIG1 mRNA CTD PMID:32699268 acrylamide decreases expression ISO RGD:731763 6480464 Acrylamide results in decreased expression of LIG1 mRNA CTD PMID:32763439 aflatoxin B1 affects expression ISO RGD:731763 6480464 Aflatoxin B1 affects the expression of LIG1 protein CTD PMID:20106945 aflatoxin B1 increases methylation ISO RGD:731763 6480464 Aflatoxin B1 results in increased methylation of LIG1 gene CTD PMID:27153756 all-trans-retinoic acid decreases expression ISO RGD:731763 6480464 Tretinoin results in decreased expression of LIG1 mRNA CTD PMID:16249480 , PMID:33167477 alpha-pinene multiple interactions ISO RGD:731763 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of LIG1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of LIG1 mRNA CTD PMID:32699268 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of LIG1 mRNA CTD PMID:16483693 arsane affects methylation ISO RGD:731763 6480464 Arsenic affects the methylation of LIG1 gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:731763 6480464 Arsenic affects the methylation of LIG1 gene CTD PMID:25304211 arsenite(3-) increases expression ISO RGD:731763 6480464 arsenite results in increased expression of LIG1 mRNA CTD PMID:15996700 aurintricarboxylic acid decreases activity ISO RGD:731763 6480464 Aurintricarboxylic Acid results in decreased activity of LIG1 protein CTD PMID:15134906 benzo[a]pyrene increases expression ISO RGD:731764 6480464 Benzo(a)pyrene results in increased expression of LIG1 mRNA CTD PMID:22228805 benzo[a]pyrene increases expression ISO RGD:731763 6480464 Benzo(a)pyrene results in increased expression of LIG1 mRNA CTD PMID:32234424 benzo[a]pyrene decreases methylation ISO RGD:731763 6480464 Benzo(a)pyrene results in decreased methylation of LIG1 5' UTR CTD PMID:27901495 benzo[a]pyrene affects methylation ISO RGD:731763 6480464 Benzo(a)pyrene affects the methylation of LIG1 intron CTD PMID:30157460 benzo[a]pyrene multiple interactions ISO RGD:731764 6480464 AHR protein inhibits the reaction [Benzo(a)pyrene results in decreased expression of LIG1 mRNA] CTD PMID:15034205 benzo[a]pyrene decreases expression ISO RGD:731764 6480464 Benzo(a)pyrene results in decreased expression of LIG1 mRNA CTD PMID:15034205 more ... biphenyl-4-amine decreases expression ISO RGD:731763 6480464 4-biphenylamine results in decreased expression of LIG1 mRNA CTD PMID:24857880 bis(2-chloroethyl) sulfide multiple interactions ISO RGD:731763 6480464 CASP3 protein affects the reaction [Mustard Gas results in increased phosphorylation of LIG1 protein] CTD PMID:16906506 bis(2-chloroethyl) sulfide increases phosphorylation ISO RGD:731763 6480464 Mustard Gas results in increased phosphorylation of LIG1 protein CTD PMID:16906506 , PMID:19845377 bis(2-chloroethyl) sulfide increases activity ISO RGD:731763 6480464 Mustard Gas results in increased activity of LIG1 protein CTD PMID:11428624 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of LIG1 mRNA CTD PMID:25181051 bisphenol A affects expression ISO RGD:731763 6480464 bisphenol A affects the expression of LIG1 mRNA CTD PMID:30903817 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of LIG1 mRNA CTD PMID:30816183 more ... bisphenol A decreases expression ISO RGD:731763 6480464 bisphenol A results in decreased expression of LIG1 mRNA CTD PMID:29275510 bisphenol A multiple interactions ISO RGD:731763 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of LIG1 mRNA CTD PMID:28628672 Brevetoxin B increases expression ISO RGD:731763 6480464 brevetoxin 2 results in increased expression of LIG1 mRNA CTD PMID:20498034 bromoacetate decreases expression ISO RGD:731763 6480464 bromoacetate results in decreased expression of LIG1 mRNA CTD PMID:19753638 cadmium dichloride increases expression ISO RGD:731764 6480464 Cadmium Chloride results in increased expression of LIG1 mRNA CTD PMID:15501611 caffeine affects phosphorylation ISO RGD:731763 6480464 Caffeine affects the phosphorylation of LIG1 protein CTD PMID:35688186 calcitriol decreases expression ISO RGD:731763 6480464 Calcitriol results in decreased expression of LIG1 mRNA CTD PMID:21592394 calcitriol multiple interactions ISO RGD:731763 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of LIG1 mRNA CTD PMID:21592394 carbamazepine affects expression ISO RGD:731763 6480464 Carbamazepine affects the expression of LIG1 mRNA CTD PMID:25979313 carbon nanotube increases expression ISO RGD:731764 6480464 Nanotubes more ... CTD PMID:25554681 carbon nanotube affects expression ISO RGD:731764 6480464 Nanotubes, Carbon affects the expression of LIG1 mRNA CTD PMID:31978390 carmustine decreases expression EXP 6480464 Carmustine results in decreased expression of LIG1 mRNA CTD PMID:16005536 cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of LIG1 mRNA CTD PMID:18500788 CGP 52608 multiple interactions ISO RGD:731763 6480464 CGP 52608 promotes the reaction [RORA protein binds to LIG1 gene] CTD PMID:28238834 choline multiple interactions ISO RGD:731764 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of LIG1 mRNA CTD PMID:22872676 cisplatin increases expression ISO RGD:731763 6480464 Cisplatin results in increased expression of LIG1 mRNA CTD PMID:27392435 , PMID:27594783 cisplatin multiple interactions ISO RGD:731763 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of LIG1 mRNA CTD PMID:27392435 copper atom multiple interactions ISO RGD:731763 6480464 [NSC 689534 binds to Copper] which results in decreased expression of LIG1 mRNA CTD PMID:20971185 copper(0) multiple interactions ISO RGD:731763 6480464 [NSC 689534 binds to Copper] which results in decreased expression of LIG1 mRNA CTD PMID:20971185 copper(II) sulfate decreases expression ISO RGD:731763 6480464 Copper Sulfate results in decreased expression of LIG1 mRNA CTD PMID:19549813 coumarin affects phosphorylation ISO RGD:731763 6480464 coumarin affects the phosphorylation of LIG1 protein CTD PMID:35688186 coumestrol multiple interactions ISO RGD:731763 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 coumestrol increases expression ISO RGD:731763 6480464 Coumestrol results in increased expression of LIG1 mRNA CTD PMID:19167446 CU-O LINKAGE increases expression ISO RGD:731763 6480464 cupric oxide results in increased expression of LIG1 mRNA CTD PMID:32285662 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of LIG1 mRNA CTD PMID:26577399 cyclosporin A decreases expression ISO RGD:731764 6480464 Cyclosporine results in decreased expression of LIG1 mRNA CTD PMID:17942131 cyclosporin A decreases expression ISO RGD:731763 6480464 Cyclosporine results in decreased expression of LIG1 mRNA CTD PMID:20106945 more ... deoxynivalenol affects phosphorylation ISO RGD:731764 6480464 deoxynivalenol affects the phosphorylation of LIG1 protein CTD PMID:23811945 dexamethasone multiple interactions ISO RGD:731763 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of LIG1 mRNA CTD PMID:28628672 diazinon increases methylation ISO RGD:731763 6480464 Diazinon results in increased methylation of LIG1 gene CTD PMID:22964155 dibutyl phthalate decreases expression ISO RGD:731764 6480464 Dibutyl Phthalate results in decreased expression of LIG1 mRNA CTD PMID:21266533 dichloroacetic acid increases expression ISO RGD:731764 6480464 Dichloroacetic Acid results in increased expression of LIG1 mRNA CTD PMID:28962523 dicrotophos increases expression ISO RGD:731763 6480464 dicrotophos results in increased expression of LIG1 mRNA CTD PMID:28302478 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of LIG1 mRNA CTD PMID:27181935 doxorubicin decreases expression ISO RGD:731763 6480464 Doxorubicin results in decreased expression of LIG1 mRNA CTD PMID:29803840 doxorubicin multiple interactions EXP 6480464 Fungal Polysaccharides inhibits the reaction [Doxorubicin results in decreased expression of LIG1 mRNA] CTD PMID:27181935 Enterolactone multiple interactions ISO RGD:731763 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LIG1 mRNA CTD PMID:19167446 ethyl methanesulfonate increases expression ISO RGD:731763 6480464 Ethyl Methanesulfonate results in increased expression of LIG1 mRNA CTD PMID:23649840 folic acid multiple interactions ISO RGD:731764 6480464 [1 more ... CTD PMID:22206623 , PMID:22872676 furan increases expression EXP 6480464 furan results in increased expression of LIG1 mRNA CTD PMID:22079235 , PMID:25539665 furan increases expression ISO RGD:731764 6480464 furan results in increased expression of LIG1 mRNA CTD PMID:20194422 hexadecanoic acid decreases phosphorylation ISO RGD:731763 6480464 Palmitic Acid results in decreased phosphorylation of LIG1 protein CTD PMID:28073184 imiquimod decreases expression ISO RGD:731764 6480464 imiquimod results in decreased expression of LIG1 mRNA CTD PMID:21878529 indometacin multiple interactions ISO RGD:731763 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of LIG1 mRNA CTD PMID:28628672 ivermectin decreases expression ISO RGD:731763 6480464 Ivermectin results in decreased expression of LIG1 protein CTD PMID:32959892 L-methionine multiple interactions ISO RGD:731764 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of LIG1 mRNA CTD PMID:22872676 methotrexate decreases expression EXP 6480464 Methotrexate results in decreased expression of LIG1 mRNA CTD PMID:16005536 methyl methanesulfonate increases expression ISO RGD:731763 6480464 Methyl Methanesulfonate results in increased expression of LIG1 mRNA CTD PMID:23649840 miconazole decreases expression EXP 6480464 Miconazole results in decreased expression of LIG1 mRNA CTD PMID:22262564 mitomycin C decreases expression ISO RGD:731763 6480464 Mitomycin results in decreased expression of LIG1 mRNA CTD PMID:12760830 N(6),N(6)-dimethyladenine multiple interactions ISO RGD:731763 6480464 N(6), N(6)-dimethyladenine inhibits the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of LIG1 protein] CTD PMID:16700562 N-methyl-4-phenylpyridinium decreases expression ISO RGD:731763 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of LIG1 mRNA CTD PMID:24810058 N-methyl-N'-nitro-N-nitrosoguanidine decreases expression ISO RGD:731763 6480464 Methylnitronitrosoguanidine results in decreased expression of LIG1 mRNA CTD PMID:12634122 N-nitrosodiethylamine multiple interactions ISO RGD:731764 6480464 RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of LIG1 mRNA] CTD PMID:17854601 N-nitrosodiethylamine increases expression ISO RGD:731764 6480464 Diethylnitrosamine results in increased expression of LIG1 mRNA CTD PMID:17854601 nickel sulfate increases expression ISO RGD:731764 6480464 nickel sulfate results in increased expression of LIG1 mRNA CTD PMID:16100012 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of LIG1 mRNA CTD PMID:25729387 oxaliplatin decreases expression EXP 6480464 oxaliplatin results in decreased expression of LIG1 mRNA CTD PMID:25729387 ozone multiple interactions ISO RGD:731764 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of LIG1 mRNA more ... CTD PMID:25658374 , PMID:34911549 ozone multiple interactions ISO RGD:731763 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of LIG1 mRNA more ... CTD PMID:32699268 paclitaxel decreases expression ISO RGD:731763 6480464 Paclitaxel results in decreased expression of LIG1 mRNA CTD PMID:15000894 paracetamol decreases expression ISO RGD:731764 6480464 Acetaminophen results in decreased expression of LIG1 mRNA CTD PMID:17942131 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of LIG1 mRNA CTD PMID:33387578 paracetamol increases expression ISO RGD:731763 6480464 Acetaminophen results in increased expression of LIG1 mRNA CTD PMID:22230336 paracetamol multiple interactions ISO RGD:731764 6480464 O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1, 2-diolate inhibits the reaction [Acetaminophen results in increased expression of LIG1 mRNA] CTD PMID:12540782 paracetamol increases expression ISO RGD:731764 6480464 Acetaminophen results in increased expression of LIG1 mRNA CTD PMID:12540782 pentachlorophenol increases expression ISO RGD:731764 6480464 Pentachlorophenol results in increased expression of LIG1 mRNA CTD PMID:23892564 perfluorononanoic acid decreases expression ISO RGD:731763 6480464 perfluoro-n-nonanoic acid results in decreased expression of LIG1 mRNA CTD PMID:32588087 phenethyl isothiocyanate decreases expression ISO RGD:731763 6480464 phenethyl isothiocyanate results in decreased expression of LIG1 mRNA CTD PMID:26678675 phenobarbital multiple interactions ISO RGD:731764 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of LIG1 mRNA] CTD PMID:19482888 phenobarbital affects expression ISO RGD:731763 6480464 Phenobarbital affects the expression of LIG1 mRNA CTD PMID:19159669 phenobarbital increases expression ISO RGD:731764 6480464 Phenobarbital results in increased expression of LIG1 mRNA CTD PMID:19482888 , PMID:23091169 pirinixic acid increases expression ISO RGD:731764 6480464 pirinixic acid results in increased expression of LIG1 mRNA CTD PMID:23811191 progesterone decreases expression ISO RGD:731764 6480464 Progesterone results in decreased expression of LIG1 mRNA CTD PMID:16966611 progesterone decreases expression EXP 6480464 Progesterone results in decreased expression of LIG1 mRNA CTD PMID:20726854 resveratrol multiple interactions ISO RGD:731763 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of LIG1 mRNA CTD PMID:19167446 resveratrol decreases expression EXP 6480464 Resveratrol results in decreased expression of LIG1 mRNA CTD PMID:33775663 rotenone decreases expression ISO RGD:731763 6480464 Rotenone results in decreased expression of LIG1 mRNA CTD PMID:33512557 sodium arsenite decreases expression ISO RGD:731763 6480464 sodium arsenite results in decreased expression of LIG1 mRNA CTD PMID:12760830 sodium arsenite affects expression ISO RGD:731763 6480464 sodium arsenite affects the expression of LIG1 mRNA CTD PMID:34032870 sodium arsenite increases expression ISO RGD:731763 6480464 sodium arsenite results in increased expression of LIG1 mRNA CTD PMID:28595984 , PMID:29301061 sodium arsenite increases expression ISO RGD:731764 6480464 sodium arsenite results in increased expression of LIG1 mRNA CTD PMID:20643705 sodium arsenite decreases expression ISO RGD:731764 6480464 sodium arsenite results in decreased expression of LIG1 mRNA CTD PMID:20643705 sodium dichromate increases expression ISO RGD:731764 6480464 sodium bichromate results in increased expression of LIG1 mRNA CTD PMID:22155349 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of LIG1 mRNA CTD PMID:22110744 sodium dichromate decreases expression ISO RGD:731764 6480464 sodium bichromate results in decreased expression of LIG1 mRNA CTD PMID:22155349 sunitinib decreases expression ISO RGD:731763 6480464 Sunitinib results in decreased expression of LIG1 mRNA CTD PMID:31533062 tamoxifen affects expression ISO RGD:731764 6480464 Tamoxifen affects the expression of LIG1 mRNA CTD PMID:17555576 tebufenpyrad increases expression ISO RGD:731763 6480464 4-chloro-N-((4-(1, 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of LIG1 mRNA CTD PMID:33512557 tert-butyl hydroperoxide decreases expression ISO RGD:731763 6480464 tert-Butylhydroperoxide results in decreased expression of LIG1 mRNA CTD PMID:15336504 tert-butyl hydroperoxide increases methylation ISO RGD:731763 6480464 tert-Butylhydroperoxide results in increased methylation of LIG1 gene CTD PMID:29432895 testosterone decreases expression ISO RGD:731763 6480464 Testosterone results in decreased expression of LIG1 mRNA CTD PMID:21592394 testosterone multiple interactions ISO RGD:731763 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of LIG1 mRNA CTD PMID:21592394 tetrachloromethane increases expression ISO RGD:731764 6480464 Carbon Tetrachloride results in increased expression of LIG1 mRNA CTD PMID:27339419 , PMID:31919559 thapsigargin decreases expression EXP 6480464 Thapsigargin results in decreased expression of LIG1 protein CTD PMID:35544339 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of LIG1 mRNA CTD PMID:34492290 tioguanine decreases expression EXP 6480464 Thioguanine results in decreased expression of LIG1 mRNA CTD PMID:16005536 titanium dioxide affects expression ISO RGD:731764 6480464 titanium dioxide affects the expression of LIG1 mRNA CTD PMID:17656681 titanium dioxide increases expression ISO RGD:731764 6480464 titanium dioxide results in increased expression of LIG1 mRNA CTD PMID:23557971 toluene 2,4-diisocyanate increases expression ISO RGD:731764 6480464 Toluene 2, 4-Diisocyanate results in increased expression of LIG1 mRNA CTD PMID:21404309 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of LIG1 mRNA CTD PMID:25729387 topotecan affects expression EXP 6480464 Topotecan affects the expression of LIG1 mRNA CTD PMID:25729387 Tributyltin oxide decreases expression ISO RGD:731764 6480464 bis(tri-n-butyltin)oxide results in decreased expression of LIG1 mRNA CTD PMID:17942131 trimellitic anhydride increases expression ISO RGD:731764 6480464 trimellitic anhydride results in increased expression of LIG1 mRNA CTD PMID:19042947 triptonide decreases expression ISO RGD:731764 6480464 triptonide results in decreased expression of LIG1 mRNA CTD PMID:33045310 troglitazone decreases expression ISO RGD:731763 6480464 troglitazone results in decreased expression of LIG1 mRNA CTD PMID:19140230 trovafloxacin decreases expression ISO RGD:731764 6480464 trovafloxacin results in decreased expression of LIG1 mRNA CTD PMID:35537566 valproic acid increases methylation ISO RGD:731763 6480464 Valproic Acid results in increased methylation of LIG1 gene CTD PMID:29154799 vorinostat decreases expression ISO RGD:731764 6480464 Vorinostat results in decreased expression of LIG1 mRNA CTD PMID:32512035 wortmannin multiple interactions ISO RGD:731763 6480464 wortmannin inhibits the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of LIG1 protein] CTD PMID:16700562