Lig1 (ligase I, DNA, ATP-dependent) - Rat Genome Database

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Gene: Lig1 (ligase I, DNA, ATP-dependent) Mus musculus
Analyze
Symbol: Lig1
Name: ligase I, DNA, ATP-dependent
RGD ID: 731764
MGI Page MGI
Description: Predicted to enable DNA ligase (ATP) activity. Acts upstream of or within DNA replication; double-strand break repair via nonhomologous end joining; and response to hydrogen peroxide. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in inherited metabolic disorder and primary immunodeficiency disease. Orthologous to human LIG1 (DNA ligase 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AL033288; DNA ligase 1; DNA ligase I; L; LigI; mL; polydeoxyribonucleotide synthase [ATP] 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39713,011,101 - 13,045,351 (+)NCBIGRCm39mm39
GRCm39 Ensembl713,011,239 - 13,045,350 (+)Ensembl
GRCm38713,277,175 - 13,311,426 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl713,277,283 - 13,311,433 (+)EnsemblGRCm38mm10GRCm38
MGSCv37713,864,175 - 13,896,776 (+)NCBIGRCm37mm9NCBIm37
MGSCv36712,177,462 - 12,211,570 (+)NCBImm8
Celera710,895,505 - 10,928,085 (+)NCBICelera
Cytogenetic Map7A1NCBI
cM Map77.82NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (EXP)
17alpha-ethynylestradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-fluorouracil  (ISO)
acetamide  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
aurintricarboxylic acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
biphenyl-4-amine  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (ISO)
Brevetoxin B  (ISO)
cadmium dichloride  (EXP)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
carmustine  (ISO)
cefaloridine  (ISO)
choline  (EXP)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (ISO)
cyclosporin A  (EXP,ISO)
deoxynivalenol  (EXP)
dexamethasone  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (EXP)
dicrotophos  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (EXP)
furan  (EXP,ISO)
hexadecanoic acid  (ISO)
imiquimod  (EXP)
indometacin  (ISO)
ivermectin  (ISO)
L-methionine  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
miconazole  (ISO)
mitomycin C  (ISO)
N(6),N(6)-dimethyladenine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP)
nickel sulfate  (EXP)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (EXP)
perfluorononanoic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (EXP)
progesterone  (EXP,ISO)
resveratrol  (ISO)
rotenone  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP,ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
tebufenpyrad  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
tioguanine  (ISO)
titanium dioxide  (EXP)
toluene 2,4-diisocyanate  (EXP)
topotecan  (ISO)
Tributyltin oxide  (EXP)
trimellitic anhydride  (EXP)
triptonide  (EXP)
troglitazone  (ISO)
valproic acid  (ISO)
vorinostat  (EXP)
wortmannin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:7576101   PMID:7642116   PMID:7671812   PMID:8039710   PMID:8674531   PMID:8696349   PMID:8812484   PMID:8889548   PMID:9001252   PMID:9149948   PMID:9363683   PMID:9859227  
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11896201   PMID:12124343   PMID:12477932   PMID:12904583   PMID:14610273   PMID:14681479   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:18784354   PMID:20300987   PMID:21267068   PMID:21378394   PMID:21390131   PMID:21655080   PMID:21677750   PMID:21873635   PMID:23154201   PMID:23469164   PMID:24457600  
PMID:24726358   PMID:26365490   PMID:26878798   PMID:27694478   PMID:28378742   PMID:28803780   PMID:30457570   PMID:30550785   PMID:32325033  


Genomics

Comparative Map Data
Lig1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39713,011,101 - 13,045,351 (+)NCBIGRCm39mm39
GRCm39 Ensembl713,011,239 - 13,045,350 (+)Ensembl
GRCm38713,277,175 - 13,311,426 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl713,277,283 - 13,311,433 (+)EnsemblGRCm38mm10GRCm38
MGSCv37713,864,175 - 13,896,776 (+)NCBIGRCm37mm9NCBIm37
MGSCv36712,177,462 - 12,211,570 (+)NCBImm8
Celera710,895,505 - 10,928,085 (+)NCBICelera
Cytogenetic Map7A1NCBI
cM Map77.82NCBI
LIG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381948,115,445 - 48,170,344 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1948,115,445 - 48,170,603 (-)EnsemblGRCh38hg38GRCh38
GRCh371948,618,702 - 48,673,601 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361953,310,515 - 53,365,372 (-)NCBINCBI36hg18NCBI36
Build 341953,310,514 - 53,365,372NCBI
Celera1945,483,843 - 45,538,716 (-)NCBI
Cytogenetic Map19q13.33NCBI
HuRef1945,000,496 - 45,055,385 (-)NCBIHuRef
CHM1_11948,620,871 - 48,675,746 (-)NCBICHM1_1
T2T-CHM13v2.01951,109,368 - 51,164,335 (-)NCBI
Lig1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2174,165,688 - 74,204,400 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl174,165,842 - 74,204,413 (+)Ensembl
Rnor_6.0175,356,212 - 75,394,757 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl175,356,220 - 75,394,758 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0176,723,841 - 76,762,378 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4173,728,892 - 73,767,429 (+)NCBIRGSC3.4rn4RGSC3.4
Celera169,539,708 - 69,578,250 (+)NCBICelera
Cytogenetic Map1q21NCBI
Lig1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955609126,278 - 160,063 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955609118,442 - 160,009 (+)NCBIChiLan1.0ChiLan1.0
LIG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11953,706,778 - 53,761,088 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1953,706,778 - 53,761,088 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01945,056,737 - 45,110,867 (-)NCBIMhudiblu_PPA_v0panPan3
LIG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11108,105,523 - 108,143,954 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1108,105,987 - 108,143,953 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1107,588,229 - 107,626,678 (+)NCBI
ROS_Cfam_1.01108,631,409 - 108,669,892 (+)NCBI
ROS_Cfam_1.0 Ensembl1108,631,442 - 108,669,892 (+)Ensembl
UMICH_Zoey_3.11108,276,098 - 108,314,538 (+)NCBI
UNSW_CanFamBas_1.01107,944,424 - 107,982,875 (+)NCBI
UU_Cfam_GSD_1.01108,812,276 - 108,850,757 (+)NCBI
Lig1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934920,624,726 - 20,658,139 (-)NCBI
SpeTri2.0NW_0049366642,242,916 - 2,276,286 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl653,620,483 - 53,686,562 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1653,620,483 - 53,660,020 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2649,204,975 - 49,270,718 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LIG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1641,354,701 - 41,405,417 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl641,351,389 - 41,403,421 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607321,141,181 - 21,192,034 (-)NCBIVero_WHO_p1.0
Lig1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,665,493 - 5,712,258 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248325,665,855 - 5,708,824 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
U04674  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7A1UniSTS
cM Map74.0UniSTS
Whitehead_YAC11 UniSTS
RH124191  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38713,311,227 - 13,311,328UniSTSGRCm38
MGSCv37713,896,576 - 13,896,677UniSTSGRCm37
Celera710,927,885 - 10,927,986UniSTS
Cytogenetic Map7A1UniSTS
cM Map74.0UniSTS
Lig1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37713,870,627 - 13,872,032UniSTSGRCm37
Celera710,901,958 - 10,903,363UniSTS
Cytogenetic Map7A1UniSTS
cM Map74.0UniSTS
Lig1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38713,285,278 - 13,286,683UniSTSGRCm38
MGSCv37713,870,627 - 13,872,032UniSTSGRCm37
Celera710,901,958 - 10,903,363UniSTS
Cytogenetic Map7A1UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301177Vent3_mventricular size 3 (mouse)Not determined7120511925Mouse
10054067Sle20_msystematic lupus erythematosus susceptibility 20 (mouse)Not determined7120511925Mouse
1302188Lxw6_mlupus BXSB x NZW 6 (mouse)Not determined7121698146Mouse
12904941Edlmmq6_mextensor digitorum longus muscle mass QTL 6 (mouse)7121821047Mouse
12904948Tammq5_mtibialis anterior muscle mass QTL 5 (mouse)7121821047Mouse
12904953Gmmq5_mgastrocnemius muscle mass QTL 5 (mouse)7121821047Mouse
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1302115Abhr3_mallergen-induced bronchial hyperresponsiveness 3 (mouse)Not determined7331599616637423Mouse
1301115Lrdm1_mlymphoproliferation (Fas) renal disease modifier 1 (mouse)Not determined7335204824879418Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25394569Skmw57_mskeletal muscle weight 57, gastroc (mouse)7458046916687861Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1678
Count of miRNA genes:520
Interacting mature miRNAs:618
Transcripts:ENSMUST00000098814, ENSMUST00000123025, ENSMUST00000123846, ENSMUST00000131294, ENSMUST00000138453, ENSMUST00000146998, ENSMUST00000147735, ENSMUST00000148471, ENSMUST00000156525, ENSMUST00000165964, ENSMUST00000177588, ENSMUST00000185145
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001083188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001199310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC161792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC028287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE996000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY099263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG954305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U04674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U19604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000098814   ⟹   ENSMUSP00000096411
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl713,012,752 - 13,045,350 (+)Ensembl
GRCm38.p6 Ensembl713,278,826 - 13,311,425 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123025   ⟹   ENSMUSP00000114872
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl713,280,146 - 13,291,244 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123846
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl713,279,265 - 13,311,433 (+)Ensembl
RefSeq Acc Id: ENSMUST00000131294
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl713,041,112 - 13,045,290 (+)Ensembl
GRCm38.p6 Ensembl713,307,187 - 13,311,365 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138453
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl713,036,738 - 13,039,936 (+)Ensembl
GRCm38.p6 Ensembl713,302,812 - 13,306,011 (+)Ensembl
RefSeq Acc Id: ENSMUST00000146998   ⟹   ENSMUSP00000121102
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl713,012,761 - 13,025,443 (+)Ensembl
GRCm38.p6 Ensembl713,278,835 - 13,291,517 (+)Ensembl
RefSeq Acc Id: ENSMUST00000147735
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl713,280,146 - 13,311,433 (+)Ensembl
RefSeq Acc Id: ENSMUST00000148471
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl713,277,283 - 13,311,425 (+)Ensembl
RefSeq Acc Id: ENSMUST00000156525
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl713,278,865 - 13,311,426 (+)Ensembl
RefSeq Acc Id: ENSMUST00000165964   ⟹   ENSMUSP00000126525
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl713,013,191 - 13,045,350 (+)Ensembl
GRCm38.p6 Ensembl713,279,265 - 13,311,425 (+)Ensembl
RefSeq Acc Id: ENSMUST00000177588   ⟹   ENSMUSP00000136972
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl713,011,239 - 13,045,350 (+)Ensembl
GRCm38.p6 Ensembl713,277,313 - 13,311,425 (+)Ensembl
RefSeq Acc Id: ENSMUST00000185145   ⟹   ENSMUSP00000138907
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl713,278,855 - 13,292,498 (+)Ensembl
RefSeq Acc Id: NM_001083188   ⟹   NP_001076657
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39713,013,191 - 13,045,351 (+)NCBI
GRCm38713,279,265 - 13,311,426 (+)NCBI
MGSCv37713,864,175 - 13,896,776 (+)RGD
Celera710,893,993 - 10,928,085 (+)ENTREZGENE
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001199310   ⟹   NP_001186239
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39713,011,101 - 13,045,351 (+)NCBI
GRCm38713,277,175 - 13,311,426 (+)NCBI
Celera710,893,993 - 10,928,085 (+)ENTREZGENE
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_010715   ⟹   NP_034845
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39713,012,752 - 13,045,351 (+)NCBI
GRCm38713,278,826 - 13,311,426 (+)NCBI
MGSCv37713,864,175 - 13,896,776 (+)RGD
Celera710,893,993 - 10,928,085 (+)ENTREZGENE
cM Map7 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034845   ⟸   NM_010715
- Sequence:
RefSeq Acc Id: NP_001076657   ⟸   NM_001083188
- Sequence:
RefSeq Acc Id: NP_001186239   ⟸   NM_001199310
- Sequence:
RefSeq Acc Id: ENSMUSP00000096411   ⟸   ENSMUST00000098814
RefSeq Acc Id: ENSMUSP00000136972   ⟸   ENSMUST00000177588
RefSeq Acc Id: ENSMUSP00000121102   ⟸   ENSMUST00000146998
RefSeq Acc Id: ENSMUSP00000138907   ⟸   ENSMUST00000185145
RefSeq Acc Id: ENSMUSP00000126525   ⟸   ENSMUST00000165964
RefSeq Acc Id: ENSMUSP00000114872   ⟸   ENSMUST00000123025
Protein Domains
DNA_LIGASE_A3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P37913-F1-model_v2 AlphaFold P37913 1-916 view protein structure

Promoters
RGD ID:6891858
Promoter ID:EPDNEW_M9380
Type:initiation region
Name:Lig1_1
Description:Mus musculus ligase I, DNA, ATP-dependent , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38713,278,826 - 13,278,886EPDNEW
RGD ID:6841421
Promoter ID:MM_KWN:48783
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:NM_001083188,   NM_001083188_LIG1,   NM_010715,   OTTMUST00000075952,   OTTMUST00000075954,   OTTMUST00000075956,   UC009FFP.1,   UC009FFQ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36713,864,201 - 13,864,701 (+)MPROMDB
RGD ID:6841424
Promoter ID:MM_KWN:48785
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000075982
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36713,888,086 - 13,888,586 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:101789 AgrOrtholog
Ensembl Genes ENSMUSG00000056394 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000096411 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000121102 UniProtKB/TrEMBL
  ENSMUSP00000126525 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000136972 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000098814 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000146998 UniProtKB/TrEMBL
  ENSMUST00000165964 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000177588 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.10.3260.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DNA_ligase_ATP-dep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_ligase_ATP-dep_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_ligase_ATP-dep_cent UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_ligase_ATP-dep_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_ligase_ATP-dep_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_ligase_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16881 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:101789 ENTREZGENE
NCBI Gene 16881 ENTREZGENE
Pfam DNA_ligase_A_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_ligase_A_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_ligase_A_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB LIG1 RGD
PhenoGen Lig1 PhenoGen
PROSITE DNA_LIGASE_A1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_LIGASE_A2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_LIGASE_A3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF117018 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50249 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs dnl1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt DNLI1_MOUSE UniProtKB/Swiss-Prot
  E9PV36_MOUSE UniProtKB/TrEMBL
  P37913 ENTREZGENE
  Q3TSU8_MOUSE UniProtKB/TrEMBL
  Q3U4X8_MOUSE UniProtKB/TrEMBL
  Q8BPJ2_MOUSE UniProtKB/TrEMBL
  Q8R055_MOUSE UniProtKB/TrEMBL