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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(-)-lariciresinol
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Accession:CHEBI:67244 term browser browse the term
Definition:A lignan that is tetrahydrofuran substituted at positions 2, 3 and 4 by 4-hydroxy-3-methoxyphenyl, hydroxymethyl and 4-hydroxy-3-methoxybenzyl groups respectively (the 2R,3S,4S-diastereomer).
Synonyms:exact_synonym: 4-[(2R,3S,4S)-4-(4-hydroxy-3-methoxybenzyl)-3-(hydroxymethyl)tetrahydrofuran-2-yl]-2-methoxyphenol
 related_synonym: Formula=C20H24O6;   InChI=1S/C20H24O6/c1-24-18-8-12(3-5-16(18)22)7-14-11-26-20(15(14)10-21)13-4-6-17(23)19(9-13)25-2/h3-6,8-9,14-15,20-23H,7,10-11H2,1-2H3/t14-,15-,20+/m1/s1;   InChIKey=MHXCIKYXNYCMHY-SXGZJXTBSA-N;   SMILES=COc1cc(C[C@@H]2CO[C@H]([C@@H]2CO)c2ccc(O)c(OC)c2)ccc1O
 xref: CAS:83327-19-9
 xref_mesh: MESH:C060282
 xref: MetaCyc:CPD-8908;   PMID:21679690;   PMID:22218086;   PMID:22466741;   PMID:8262939;   Reaxys:5622895
 cyclic_relationship: is_enantiomer_of CHEBI:67246


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(-)-lariciresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 increases expression ISO lariciresinol results in increased expression of ANXA1 protein CTD PMID:27417256 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 decreases expression ISO lariciresinol results in decreased expression of BASP1 protein CTD PMID:27417256 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043 		JBrowse link
G Gale UDP-galactose-4-epimerase increases expression ISO lariciresinol results in increased expression of GALE protein CTD PMID:27417256 NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388 		JBrowse link
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic increases expression ISO lariciresinol results in increased expression of GAPDHS protein CTD PMID:27417256 NCBI chr 1:85,979,096...85,994,153
Ensembl chr 1:85,979,098...85,993,640 		JBrowse link
G Hp haptoglobin decreases expression ISO lariciresinol results in decreased expression of HP protein CTD PMID:27417256 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression ISO lariciresinol results in decreased expression of HSPB1 protein CTD PMID:27417256 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Tmod2 tropomodulin 2 decreases expression ISO lariciresinol results in decreased expression of TMOD2 protein CTD PMID:27417256 NCBI chr 8:76,316,736...76,366,003
Ensembl chr 8:76,325,667...76,365,720 		JBrowse link
G Tuba1a tubulin, alpha 1A decreases expression ISO lariciresinol results in decreased expression of TUBA1A protein CTD PMID:27417256 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Ubc ubiquitin C increases expression ISO lariciresinol results in increased expression of UBC protein CTD PMID:27417256 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20845
    chemical entity 20843
      molecular entity 20842
        polyatomic entity 20786
          heteroatomic molecular entity 20723
            hydroxides 20216
              organic hydroxy compound 19754
                phenols 19420
                  (-)-lariciresinol 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 20845
    subatomic particle 20843
      composite particle 20843
        hadron 20843
          baryon 20843
            nucleon 20843
              atomic nucleus 20843
                atom 20843
                  main group element atom 20766
                    p-block element atom 20766
                      carbon group element atom 20699
                        carbon atom 20693
                          organic molecular entity 20693
                            organic molecule 20637
                              organic cyclic compound 20387
                                organic aromatic compound 20222
                                  phenylpropanoid 11384
                                    lignan 1711
                                      (-)-lariciresinol 9
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