Gene: Slf1 (SMC5-SMC6 complex localization factor 1) Rattus norvegicus
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Symbol: Slf1
Name: SMC5-SMC6 complex localization factor 1
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN cellular response to DNA damage stimulus (ortholog); positive regulation of double-strand break repair (ortholog); positive regulation of maintenance of mitotic sister chromatid cohesion (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); nuclear inclusion body (ortholog); INTERACTS WITH bisphenol A; trichloroethene; 2,3,7,8-tetrachlorodibenzodioxine (ortholog)
AGR Description: Predicted to have ubiquitin protein ligase binding activity; predicted to be involved in several processes, including cellular response to DNA damage stimulus, positive regulation of cellular component organization, and positive regulation of double-strand break repair; predicted to localize to several cellular components, including the cytoplasm and intracellular organelle; orthologous to human SLF1 (SMC5-SMC6 complex localization factor 1).
Merged Description: Predicted to have ubiquitin protein ligase binding activity; predicted to be involved in several processes, including cellular response to DNA damage stimulus, positive regulation of cellular component organization, and positive regulation of double-strand break repair; predicted to localize to several cellular components, including the cytoplasm and intracellular organelle; orthologous to human SLF1 (SMC5-SMC6 complex localization factor 1); INTERACTS WITH bisphenol A; trichloroethene; 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ankrd32; ankyrin repeat domain 32; ankyrin repeat domain-containing protein 32; LOC294601; SMC5-SMC6 complex localization factor protein 1
Orthologs:
Homo sapiens (human) : SLF1 (SMC5-SMC6 complex localization factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Slf1 (SMC5-SMC6 complex localization factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slf1 (SMC5-SMC6 complex localization factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLF1 (SMC5-SMC6 complex localization factor 1)
Canis lupus familiaris (dog) : SLF1 (SMC5-SMC6 complex localization factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slf1 (SMC5-SMC6 complex localization factor 1)
Sus scrofa (pig) : SLF1 (SMC5-SMC6 complex localization factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.024,095,126 - 4,195,819 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.024,092,109 - 4,193,740 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.424,361,776 - 4,469,805 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.124,436,397 - 4,492,122 (-)NCBI
Celera23,225,433 - 3,326,221 (-)NCBICelera
Cytogenetic Map2q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Slf1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304857
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.