Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


go back to main search page
Accession:CHEBI:4429 term browser browse the term
Definition:A member of the class of furonaphthodioxoles that is (5R,5aR,8aR)-5,8,8a,9-tetrahydro-2H-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one substituted at position 5 by a 3,4,5-trimethoxyphenyl group.
Synonyms:exact_synonym: (5R,5aR,8aR)-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydro-2H-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
 related_synonym: 4-Deoxypodophyllotoxin;   Anthricin;   Desoxypodophyllotoxin;   Formula=C22H22O7;   Hernandin;   Hernandion;   InChI=1S/C22H22O7/c1-24-17-6-12(7-18(25-2)21(17)26-3)19-14-8-16-15(28-10-29-16)5-11(14)4-13-9-27-22(23)20(13)19/h5-8,13,19-20H,4,9-10H2,1-3H3/t13-,19+,20-/m0/s1;   InChIKey=ZGLXUQQMLLIKAN-SVIJTADQSA-N;   SMILES=[C@H]1(C2=C(C[C@@]3([C@@]1(C(OC3)=O)[H])[H])C=C4OCOC4=C2)C5=CC(=C(OC)C(=C5)OC)OC;   Silicicolin
 xref: CAS:19186-35-7 "ChemIDplus";   CAS:19186-35-7 "KEGG COMPOUND";   CAS:19186-35-7 "NIST Chemistry WebBook";   KEGG:C10556;   KNApSAcK:C00002597
 xref_mesh: MESH:C014451
 xref: MetaCyc:CPD-8958;   PMID:24176745 "Europe PMC";   PMID:24913660 "Europe PMC";   PMID:25608854 "Europe PMC";   PMID:25712646 "Europe PMC";   PMID:25720974 "Europe PMC";   PMID:26470595 "Europe PMC";   PMID:26573436 "Europe PMC";   PMID:26683770 "Europe PMC";   Reaxys:98060 "Reaxys"

show annotations for term's descendants       view all columns           Sort by:
deoxypodophyllotoxin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acaca acetyl-CoA carboxylase alpha JBrowse link 10 71,519,392 71,719,910 RGD:6480464
G Fasn fatty acid synthase JBrowse link 10 109,987,735 110,005,901 RGD:6480464
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:6480464
G Scd stearoyl-CoA desaturase JBrowse link 1 264,159,966 264,173,061 RGD:6480464
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:6480464
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      biological role 19604
        biochemical role 19133
          apoptosis inducer 10823
            deoxypodophyllotoxin 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      carbon group element atom 19422
                        carbon atom 19414
                          organic molecular entity 19414
                            organic group 18340
                              organic divalent group 18330
                                organodiyl group 18330
                                  carbonyl group 18217
                                    carbonyl compound 18217
                                      carboxylic ester 13954
                                        lactone 5864
                                          gamma-lactone 1196
                                            deoxypodophyllotoxin 6
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.