(+)-catechin multiple interactions ISO RGD:1604850 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of CASP2 mRNA CTD PMID:24763279 (+)-dexrazoxane increases expression ISO RGD:731460 6480464 Dexrazoxane results in increased expression of CASP2 mRNA CTD PMID:26873546 (-)-citrinin decreases expression ISO RGD:1604850 6480464 Citrinin results in decreased expression of CASP2 mRNA CTD PMID:30428381 (-)-citrinin multiple interactions ISO RGD:1604850 6480464 [Citrinin co-treated with ochratoxin A] results in decreased expression of CASP2 mRNA CTD PMID:30428381 (-)-demecolcine decreases expression ISO RGD:1604850 6480464 Demecolcine results in decreased expression of CASP2 mRNA CTD PMID:23649840 (R)-noradrenaline multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP2 protein], Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP2 protein] CTD PMID:15158148 , PMID:17041759 (R)-noradrenaline increases activity EXP 6480464 Norepinephrine results in increased activity of CASP2 protein CTD PMID:14732211 more ... (S)-naringenin multiple interactions ISO RGD:1604850 6480464 [naringenin co-treated with bisphenol A] results in increased expression of CASP2 mRNA, [naringenin metabolite co-treated with bisphenol A] results in increased expression of CASP2 mRNA CTD PMID:36235125 (S)-naringenin increases expression ISO RGD:1604850 6480464 naringenin results in increased expression of CASP2 mRNA CTD PMID:36235125 (S)-nicotine affects expression EXP 6480464 Nicotine affects the expression of CASP2 mRNA CTD PMID:20426880 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression EXP 6480464 o more ... CTD PMID:22937105 1,2-dimethylhydrazine decreases expression ISO RGD:731460 6480464 1, 2-Dimethylhydrazine results in decreased expression of CASP2 mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO RGD:731460 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CASP2 mRNA CTD PMID:22206623 1-nitropyrene increases activity ISO RGD:731460 6480464 1-nitropyrene results in increased activity of CASP2 protein CTD PMID:21872649 17alpha-ethynylestradiol affects expression ISO RGD:731460 6480464 Ethinyl Estradiol affects the expression of CASP2 mRNA CTD PMID:17555576 17alpha-ethynylestradiol multiple interactions ISO RGD:731460 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of CASP2 mRNA CTD PMID:17942748 17beta-estradiol affects expression ISO RGD:731460 6480464 Estradiol affects the expression of CASP2 mRNA CTD PMID:15598610 17beta-estradiol decreases expression ISO RGD:1604850 6480464 Estradiol results in decreased expression of CASP2 mRNA CTD PMID:20106945 , PMID:21632981 17beta-estradiol affects expression ISO RGD:1604850 6480464 Estradiol affects the expression of CASP2 mRNA CTD PMID:21826169 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:731460 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of CASP2 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1604850 6480464 Tetrachlorodibenzodioxin affects the expression of CASP2 mRNA CTD PMID:22574217 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:731460 6480464 Tetrachlorodibenzodioxin affects the expression of CASP2 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:731460 6480464 Tetrachlorodibenzodioxin results in increased expression of CASP2 mRNA CTD PMID:12167310 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of CASP2 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of CASP2 mRNA CTD PMID:21346803 2-methoxyethanol increases expression EXP 6480464 methyl cellosolve results in increased expression of CASP2 mRNA CTD PMID:22008535 3,3',5,5'-tetraiodothyroacetic acid increases expression ISO RGD:1604850 6480464 tetraiodothyroacetic acid results in increased expression of CASP2 mRNA CTD PMID:35151786 3,3',5,5'-tetraiodothyroacetic acid decreases expression ISO RGD:1604850 6480464 tetraiodothyroacetic acid results in decreased expression of CASP2 mRNA CTD PMID:35151786 3,3',5,5'-tetraiodothyroacetic acid multiple interactions ISO RGD:1604850 6480464 heteronemin inhibits the reaction [tetraiodothyroacetic acid results in increased expression of CASP2 mRNA] more ... CTD PMID:35151786 3-chloropropane-1,2-diol decreases expression ISO RGD:1604850 6480464 alpha-Chlorohydrin results in decreased expression of CASP2 mRNA CTD PMID:27732882 3-chloropropane-1,2-diol multiple interactions ISO RGD:1604850 6480464 alpha-Chlorohydrin results in increased expression of and results in increased cleavage of and results in increased activity of CASP2 protein, quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP2 protein] CTD PMID:27732882 3-nitropropanoic acid increases activity EXP 6480464 3-nitropropionic acid results in increased activity of CASP2 protein CTD PMID:15571979 4,4'-sulfonyldiphenol decreases methylation ISO RGD:1604850 6480464 bis(4-hydroxyphenyl)sulfone results in decreased methylation of CASP2 gene CTD PMID:31601247 4-hydroxyphenyl retinamide multiple interactions ISO RGD:1604850 6480464 4-((4-(4-ethylphenyl)-2 more ... CTD PMID:16972258 4-hydroxyphenyl retinamide increases activity ISO RGD:1604850 6480464 Fenretinide results in increased activity of CASP2 protein CTD PMID:16972258 4-nitrophenol increases expression ISO RGD:731460 6480464 4-nitrophenol results in increased expression of CASP2 mRNA CTD PMID:34673133 4-nonylphenol increases expression EXP 6480464 4-nonylphenol results in increased expression of CASP2 mRNA CTD PMID:27087316 4-vinylcyclohexene dioxide increases expression ISO RGD:731460 6480464 4-vinyl-1-cyclohexene dioxide results in increased expression of CASP2 protein modified form CTD PMID:20829426 5-fluorouracil decreases expression ISO RGD:1604850 6480464 Fluorouracil results in decreased expression of CASP2 mRNA CTD PMID:34151400 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of CASP2 mRNA CTD PMID:24780913 7,12-dimethyltetraphene increases expression ISO RGD:731460 6480464 9 more ... CTD PMID:21785161 acrolein decreases expression ISO RGD:731460 6480464 Acrolein results in decreased expression of CASP2 mRNA CTD PMID:18515264 actinomycin D increases cleavage ISO RGD:1604850 6480464 Dactinomycin results in increased cleavage of CASP2 protein CTD PMID:10663630 ammonium chloride increases activity EXP 6480464 Ammonium Chloride results in increased activity of CASP2 protein CTD PMID:18722528 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CASP2 mRNA CTD PMID:16483693 amphetamine increases activity EXP 6480464 Amphetamine results in increased activity of CASP2 protein CTD PMID:16638611 amsacrine increases expression ISO RGD:1604850 6480464 Amsacrine results in increased expression of CASP2 mRNA alternative form CTD PMID:14757846 amsacrine increases splicing ISO RGD:1604850 6480464 Amsacrine results in increased splicing of CASP2 mRNA CTD PMID:14757846 anthra[1,9-cd]pyrazol-6(2H)-one decreases activity ISO RGD:1604850 6480464 pyrazolanthrone results in decreased activity of CASP2 protein CTD PMID:17317842 arsane increases expression ISO RGD:1604850 6480464 Arsenic results in increased expression of CASP2 mRNA CTD PMID:19962721 , PMID:27838757 arsenic atom increases expression ISO RGD:1604850 6480464 Arsenic results in increased expression of CASP2 mRNA CTD PMID:19962721 , PMID:27838757 arsenous acid increases expression ISO RGD:1604850 6480464 Arsenic Trioxide results in increased expression of CASP2, Arsenic Trioxide results in increased expression of CASP2 mRNA CTD PMID:17530438 , PMID:9801394 arsenous acid decreases expression ISO RGD:731460 6480464 Arsenic Trioxide results in decreased expression of CASP2 mRNA CTD PMID:15073043 benzene increases expression EXP 6480464 Benzene results in increased expression of CASP2 protein CTD PMID:17171516 benzo[a]pyrene increases activity EXP 6480464 Benzo(a)pyrene results in increased activity of CASP2 protein CTD PMID:22051199 benzo[a]pyrene increases expression ISO RGD:1604850 6480464 Benzo(a)pyrene results in increased expression of CASP2 mRNA CTD PMID:32234424 benzo[a]pyrene increases expression ISO RGD:731460 6480464 Benzo(a)pyrene results in increased expression of CASP2 protein CTD PMID:22342234 benzo[a]pyrene multiple interactions EXP 6480464 Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in increased activity of CASP2 protein] CTD PMID:22051199 bis(2-chloroethyl) sulfide increases activity ISO RGD:1604850 6480464 Mustard Gas results in increased activity of CASP2 protein CTD PMID:16738803 bisphenol A affects expression ISO RGD:1604850 6480464 bisphenol A affects the expression of CASP2 mRNA CTD PMID:21826169 bisphenol A multiple interactions ISO RGD:1604850 6480464 [naringenin co-treated with bisphenol A] results in increased expression of CASP2 mRNA, [naringenin metabolite co-treated with bisphenol A] results in increased expression of CASP2 mRNA CTD PMID:36235125 bisphenol A increases expression ISO RGD:1604850 6480464 bisphenol A results in increased expression of CASP2 mRNA CTD PMID:36235125 bisphenol A increases expression ISO RGD:731460 6480464 bisphenol A results in increased expression of CASP2 mRNA CTD PMID:33221593 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CASP2 mRNA CTD PMID:30816183 more ... bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of CASP2 mRNA CTD PMID:25181051 bortezomib multiple interactions ISO RGD:1604850 6480464 benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Bortezomib results in increased cleavage of and results in increased activity of CASP2 protein] more ... CTD PMID:16446371 , PMID:18723477 bortezomib increases response to substance ISO RGD:1604850 6480464 CASP2 results in increased susceptibility to Bortezomib CTD PMID:18723477 bortezomib increases cleavage ISO RGD:1604850 6480464 Bortezomib results in increased cleavage of CASP2 protein CTD PMID:15509775 brefeldin A multiple interactions ISO RGD:1604850 6480464 Bortezomib promotes the reaction [Brefeldin A results in increased cleavage of and results in increased activity of CASP2 protein] more ... CTD PMID:18723477 butan-1-ol multiple interactions ISO RGD:1604850 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of CASP2 mRNA CTD PMID:29432896 butanal increases expression ISO RGD:1604850 6480464 butyraldehyde results in increased expression of CASP2 mRNA CTD PMID:26079696 cadmium atom multiple interactions ISO RGD:1604850 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CASP2 mRNA CTD PMID:35301059 cadmium dichloride increases expression ISO RGD:1604850 6480464 Cadmium Chloride results in increased expression of CASP2 mRNA CTD PMID:12160620 cadmium dichloride multiple interactions ISO RGD:1604850 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CASP2 mRNA CTD PMID:35301059 cadmium dichloride decreases expression ISO RGD:1604850 6480464 Cadmium Chloride results in decreased expression of CASP2 mRNA CTD PMID:19426795 caffeine multiple interactions ISO RGD:1604850 6480464 Caffeine inhibits the reaction [silybin results in increased cleavage of and results in increased activity of CASP2 protein] CTD PMID:16777994 caffeine increases phosphorylation ISO RGD:1604850 6480464 Caffeine results in increased phosphorylation of CASP2 protein CTD PMID:35688186 camptothecin increases splicing ISO RGD:1604850 6480464 Camptothecin results in increased splicing of CASP2 mRNA CTD PMID:14757846 camptothecin increases expression ISO RGD:1604850 6480464 Camptothecin results in increased expression of CASP2 mRNA alternative form CTD PMID:14757846 cannabidiol multiple interactions ISO RGD:1604850 6480464 [Cannabidiol co-treated with moringin] results in increased expression of CASP2 mRNA CTD PMID:30096889 capsaicin multiple interactions ISO RGD:1604850 6480464 [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP2 protein CTD PMID:19939880 carbamazepine affects expression ISO RGD:1604850 6480464 Carbamazepine affects the expression of CASP2 mRNA CTD PMID:24752500 carbon nanotube increases expression ISO RGD:1604850 6480464 Nanotubes, Carbon results in increased expression of CASP2 mRNA CTD PMID:23634900 carboplatin decreases expression EXP 6480464 Carboplatin results in decreased expression of CASP2 mRNA CTD PMID:18172885 casticin increases expression ISO RGD:1604850 6480464 casticin results in increased expression of CASP2 protein CTD PMID:27862857 CGP 52608 multiple interactions ISO RGD:1604850 6480464 CGP 52608 promotes the reaction [RORA protein binds to CASP2 gene] CTD PMID:28238834 chelerythrine increases cleavage ISO RGD:1604850 6480464 chelerythrine results in increased cleavage of CASP2 protein CTD PMID:26124276 chromium(6+) increases activity ISO RGD:1604850 6480464 chromium hexavalent ion results in increased activity of CASP2 protein CTD PMID:15831465 chromium(6+) multiple interactions ISO RGD:1604850 6480464 MLH1 protein affects the reaction [chromium hexavalent ion results in increased activity of CASP2 protein] CTD PMID:15831465 Cinobufotalin increases cleavage ISO RGD:1604850 6480464 cinobufotalin results in increased cleavage of CASP2 protein CTD PMID:22898211 cisplatin increases cleavage ISO RGD:1604850 6480464 Cisplatin results in increased cleavage of CASP2 protein CTD PMID:10663630 cisplatin multiple interactions ISO RGD:1604850 6480464 ESR2 protein promotes the reaction [Cisplatin results in increased expression of CASP2 protein] CTD PMID:20623183 cisplatin increases expression ISO RGD:1604850 6480464 Cisplatin results in increased expression of CASP2 protein CTD PMID:20623183 cisplatin multiple interactions ISO RGD:731460 6480464 pifithrin inhibits the reaction [Cisplatin results in increased activity of CASP2 protein] CTD PMID:15983031 cisplatin increases activity ISO RGD:731460 6480464 Cisplatin results in increased activity of CASP2 protein CTD PMID:15983031 clonidine increases activity ISO RGD:1604850 6480464 Clonidine results in increased activity of CASP2 protein CTD PMID:28115640 clonidine (amino form) increases activity ISO RGD:1604850 6480464 Clonidine results in increased activity of CASP2 protein CTD PMID:28115640 clonidine (imino form) increases activity ISO RGD:1604850 6480464 Clonidine results in increased activity of CASP2 protein CTD PMID:28115640 cocaine increases activity EXP 6480464 Cocaine results in increased activity of CASP2 protein CTD PMID:16638611 cocaine increases expression EXP 6480464 Cocaine results in increased expression of CASP2 mRNA CTD PMID:16076954 copper(II) sulfate decreases expression ISO RGD:1604850 6480464 Copper Sulfate results in decreased expression of CASP2 mRNA CTD PMID:19549813 coumarin increases phosphorylation ISO RGD:1604850 6480464 coumarin results in increased phosphorylation of CASP2 protein CTD PMID:35688186 crocidolite asbestos increases expression EXP 6480464 Asbestos, Crocidolite results in increased expression of CASP2 mRNA CTD PMID:12909582 curcumin increases expression ISO RGD:1604850 6480464 Curcumin results in increased expression of CASP2 mRNA CTD PMID:16101141 cyclosporin A decreases expression ISO RGD:1604850 6480464 Cyclosporine results in decreased expression of CASP2 mRNA CTD PMID:25562108 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of CASP2 mRNA CTD PMID:14618091 dexamethasone decreases expression ISO RGD:731460 6480464 Dexamethasone results in decreased expression of CASP2 mRNA CTD PMID:21041162 diarsenic trioxide increases expression ISO RGD:1604850 6480464 Arsenic Trioxide results in increased expression of CASP2, Arsenic Trioxide results in increased expression of CASP2 mRNA CTD PMID:17530438 , PMID:9801394 diarsenic trioxide decreases expression ISO RGD:731460 6480464 Arsenic Trioxide results in decreased expression of CASP2 mRNA CTD PMID:15073043 diazinon affects expression EXP 6480464 Diazinon affects the expression of CASP2 mRNA CTD PMID:22546817 diclofenac multiple interactions ISO RGD:1604850 6480464 Diclofenac inhibits the reaction [Thapsigargin results in increased activity of CASP2 protein], Diclofenac inhibits the reaction [Tunicamycin results in increased activity of CASP2 protein] CTD PMID:16388830 diclofenac affects expression ISO RGD:1604850 6480464 Diclofenac affects the expression of CASP2 mRNA CTD PMID:24752500 dicrotophos increases expression ISO RGD:1604850 6480464 dicrotophos results in increased expression of CASP2 mRNA CTD PMID:28302478 diepoxybutane increases expression ISO RGD:1604850 6480464 diepoxybutane results in increased expression of CASP2 mRNA CTD PMID:29792945 diethyl maleate increases expression ISO RGD:1604850 6480464 diethyl maleate results in increased expression of CASP2 mRNA CTD PMID:11875189 diethylstilbestrol decreases expression ISO RGD:731460 6480464 Diethylstilbestrol results in decreased expression of CASP2 mRNA CTD PMID:21041162 dimethylarsinic acid increases expression ISO RGD:1604850 6480464 Cacodylic Acid analog results in increased expression of CASP2 protein CTD PMID:23994116 doxorubicin increases response to substance ISO RGD:1604850 6480464 CASP2 protein results in increased susceptibility to Doxorubicin CTD PMID:15917298 doxorubicin increases activity ISO RGD:1604850 6480464 Doxorubicin results in increased activity of CASP2 protein CTD PMID:15917298 more ... doxorubicin increases activity EXP 6480464 Doxorubicin results in increased activity of CASP2 protein CTD PMID:19801490 doxorubicin multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [NRG1 protein inhibits the reaction [Doxorubicin results in increased activity of CASP2 protein]] more ... CTD PMID:16687611 , PMID:19801490 doxorubicin decreases expression ISO RGD:731460 6480464 Doxorubicin results in decreased expression of CASP2 mRNA CTD PMID:16439991 doxorubicin increases splicing ISO RGD:1604850 6480464 Doxorubicin results in increased splicing of CASP2 mRNA CTD PMID:14757846 doxorubicin increases expression ISO RGD:1604850 6480464 Doxorubicin results in increased expression of CASP2 mRNA alternative form CTD PMID:14757846 doxorubicin multiple interactions ISO RGD:1604850 6480464 benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Doxorubicin promotes the reaction [CASP2 protein results in increased cleavage of PRKCD protein]] more ... CTD PMID:15917298 , PMID:30769864 endosulfan multiple interactions EXP 6480464 [Endosulfan results in increased activity of CASP2 protein] which results in increased cleavage of BECN1 protein, Endosulfan results in increased cleavage of and results in increased activity of CASP2 protein CTD PMID:30796443 epichlorohydrin decreases expression ISO RGD:1604850 6480464 Epichlorohydrin results in decreased expression of CASP2 mRNA CTD PMID:29792945 ethanol multiple interactions ISO RGD:1604850 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of CASP2 mRNA CTD PMID:29432896 etoposide increases expression ISO RGD:1604850 6480464 Etoposide results in increased expression of CASP2 mRNA alternative form CTD PMID:14757846 etoposide increases splicing ISO RGD:1604850 6480464 Etoposide results in increased splicing of CASP2 mRNA CTD PMID:14757846 flavanones increases cleavage ISO RGD:1604850 6480464 Flavanones results in increased cleavage of CASP2 protein CTD PMID:21616090 flavanones multiple interactions ISO RGD:1604850 6480464 U 0126 promotes the reaction [Flavanones results in increased cleavage of CASP2 protein] CTD PMID:21616090 folic acid multiple interactions ISO RGD:731460 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CASP2 mRNA CTD PMID:22206623 furan increases expression EXP 6480464 furan results in increased expression of CASP2 mRNA CTD PMID:22079235 furosemide affects expression EXP 6480464 Furosemide affects the expression of CASP2 mRNA CTD PMID:17497460 gardenin B multiple interactions ISO RGD:1604850 6480464 gardenin B results in increased cleavage of and results in increased activity of CASP2 protein CTD PMID:27423764 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of CASP2 mRNA CTD PMID:22061828 glycyrrhizinic acid multiple interactions EXP 6480464 Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in increased activity of CASP2 protein] CTD PMID:22051199 glyphosate decreases expression ISO RGD:1604850 6480464 glyphosate results in decreased expression of CASP2 mRNA CTD PMID:31295307 hydrogen peroxide multiple interactions ISO RGD:1604850 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of CASP2 protein, [sodium cyanate co-treated with Hydrogen Peroxide] results in increased activity of CASP2 protein CTD PMID:18951874 , PMID:28400100 hydrogen peroxide increases activity ISO RGD:1604850 6480464 Hydrogen Peroxide results in increased activity of CASP2 protein CTD PMID:28400100 isobutanol multiple interactions ISO RGD:1604850 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of CASP2 mRNA CTD PMID:29432896 isoflurane increases expression EXP 6480464 Isoflurane results in increased expression of CASP2 mRNA CTD PMID:16978161 isoprenaline decreases expression EXP 6480464 Isoproterenol results in decreased expression of CASP2 mRNA CTD PMID:24286936 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of CASP2 mRNA CTD PMID:24286936 L-ascorbic acid multiple interactions EXP 6480464 Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP2 protein] CTD PMID:15158148 leflunomide decreases expression ISO RGD:1604850 6480464 leflunomide results in decreased expression of CASP2 mRNA CTD PMID:28988120 lipopolysaccharide decreases expression ISO RGD:731460 6480464 Lipopolysaccharides results in decreased expression of CASP2 mRNA CTD PMID:12057914 lithocholic acid multiple interactions ISO RGD:1604850 6480464 benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Lithocholic Acid results in increased cleavage of and results in increased activity of CASP2 protein], Lithocholic Acid results in increased cleavage of and results in increased activity of CASP2 protein CTD PMID:19054763 lovastatin increases activity ISO RGD:1604850 6480464 Lovastatin results in increased activity of CASP2 protein CTD PMID:12933658 lovastatin multiple interactions ISO RGD:731460 6480464 Lovastatin promotes the reaction [RHOB protein binds to CASP2 protein] CTD PMID:16234849 lovastatin increases activity ISO RGD:731460 6480464 Lovastatin results in increased activity of CASP2 protein CTD PMID:16234849 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [NRG1 protein inhibits the reaction [Doxorubicin results in increased activity of CASP2 protein]] CTD PMID:19801490 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of CASP2 mRNA CTD PMID:28801915 mechlorethamine increases activity ISO RGD:1604850 6480464 Mechlorethamine results in increased activity of CASP2 protein CTD PMID:16738803 menadione increases expression ISO RGD:731460 6480464 Vitamin K 3 results in increased expression of CASP2 protein modified form CTD PMID:20829426 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of CASP2 mRNA CTD PMID:19564919 methotrexate increases expression ISO RGD:1604850 6480464 Methotrexate results in increased expression of CASP2 mRNA CTD PMID:24449571 methoxychlor increases expression ISO RGD:731460 6480464 Methoxychlor results in increased expression of CASP2 protein modified form CTD PMID:20829426 methyl methanesulfonate increases expression ISO RGD:1604850 6480464 Methyl Methanesulfonate results in increased expression of CASP2 mRNA CTD PMID:23649840 Mitotane increases expression EXP 6480464 Mitotane results in increased expression of CASP2 mRNA CTD PMID:23485034 mitoxantrone increases expression ISO RGD:1604850 6480464 Mitoxantrone results in increased expression of CASP2 mRNA alternative form CTD PMID:14757846 mitoxantrone increases splicing ISO RGD:1604850 6480464 Mitoxantrone results in increased splicing of CASP2 mRNA CTD PMID:14757846 Myrtucommulone A decreases expression ISO RGD:731460 6480464 myrtucommulone A results in decreased expression of CASP2 mRNA CTD PMID:26032814 N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester decreases expression ISO RGD:1604850 6480464 flupirtine results in decreased expression of CASP2 protein CTD PMID:9804146 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP2 protein] CTD PMID:15158148 , PMID:17041759 N-acetyl-L-cysteine multiple interactions ISO RGD:1604850 6480464 Acetylcysteine inhibits the reaction [2-hydroxy-3' more ... CTD PMID:30408460 N-acetyl-L-cysteine multiple interactions ISO RGD:731460 6480464 Acetylcysteine inhibits the reaction [[CASP2 protein affects the susceptibility to Rotenone] which results in increased expression of BECN1 protein], Acetylcysteine inhibits the reaction [Rotenone results in increased cleavage of CASP2 protein] CTD PMID:21216964 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of CASP2 mRNA CTD PMID:22546817 nicotine affects expression EXP 6480464 Nicotine affects the expression of CASP2 mRNA CTD PMID:20426880 norfloxacin affects activity ISO RGD:1604850 6480464 Norfloxacin affects the activity of CASP2 protein CTD PMID:32320760 NS-398 multiple interactions ISO RGD:1604850 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased expression of CASP2 mRNA], SUMO1 protein affects the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased expression of CASP2 mRNA]] CTD PMID:29242151 ochratoxin A multiple interactions ISO RGD:1604850 6480464 [Citrinin co-treated with ochratoxin A] results in decreased expression of CASP2 mRNA CTD PMID:30428381 ochratoxin A decreases expression ISO RGD:1604850 6480464 ochratoxin A results in decreased expression of CASP2 mRNA CTD PMID:30428381 orphenadrine affects expression EXP 6480464 Orphenadrine affects the expression of CASP2 mRNA CTD PMID:23665939 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of CASP2 mRNA CTD PMID:25729387 oxybenzone increases expression EXP 6480464 oxybenzone results in increased expression of CASP2 mRNA CTD PMID:30316929 p-menthan-3-ol decreases expression ISO RGD:1604850 6480464 Menthol results in decreased expression of CASP2 mRNA CTD PMID:26760959 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of CASP2 mRNA CTD PMID:16701773 paraquat decreases expression ISO RGD:1604850 6480464 Paraquat results in decreased expression of CASP2 mRNA CTD PMID:18836921 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of CASP2 mRNA CTD PMID:19162173 phenylephrine affects activity ISO RGD:1604850 6480464 Phenylephrine affects the activity of CASP2 protein CTD PMID:31605733 picoxystrobin decreases expression ISO RGD:1604850 6480464 picoxystrobin results in decreased expression of CASP2 mRNA CTD PMID:33512557 picrotoxin increases expression EXP 6480464 Picrotoxin results in increased expression of CASP2 mRNA CTD PMID:15170462 podophyllotoxin increases activity ISO RGD:1604850 6480464 Podophyllotoxin results in increased activity of CASP2 protein CTD PMID:21916509 Pranoprofen increases activity ISO RGD:1604850 6480464 pyranoprofen results in increased activity of CASP2 protein CTD PMID:31765691 propylparaben increases expression ISO RGD:1604850 6480464 propylparaben results in increased expression of CASP2 mRNA CTD PMID:24481588 quercetin increases activity ISO RGD:1604850 6480464 Quercetin results in increased activity of CASP2 protein CTD PMID:22555976 resveratrol multiple interactions ISO RGD:1604850 6480464 [resveratrol co-treated with TNFSF10 protein] results in increased activity of CASP2 protein more ... CTD PMID:15763656 more ... resveratrol increases expression ISO RGD:1604850 6480464 resveratrol results in increased expression of CASP2 mRNA CTD PMID:25436977 more ... resveratrol decreases expression ISO RGD:1604850 6480464 resveratrol results in decreased expression of CASP2 protein CTD PMID:18089832 rotenone decreases expression ISO RGD:731460 6480464 Rotenone results in decreased expression of CASP2 mRNA CTD PMID:23186747 rotenone multiple interactions ISO RGD:731460 6480464 [CASP2 protein affects the susceptibility to Rotenone] which results in increased expression of BECN1 protein more ... CTD PMID:21216964 rotenone affects response to substance ISO RGD:731460 6480464 CASP2 protein affects the susceptibility to Rotenone CTD PMID:21216964 silibinin multiple interactions ISO RGD:1604850 6480464 benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP2 protein] more ... CTD PMID:16777994 silicon dioxide decreases expression ISO RGD:731460 6480464 Silicon Dioxide results in decreased expression of CASP2 mRNA CTD PMID:19073995 , PMID:33720480 sirolimus multiple interactions ISO RGD:1604850 6480464 [Boc-D-FMK co-treated with Sirolimus] results in increased cleavage of CASP2 protein, Boc-D-FMK inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] results in increased cleavage of CASP2 protein] CTD PMID:15767555 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of CASP2 mRNA CTD PMID:19072884 sodium arsenite decreases expression ISO RGD:1604850 6480464 sodium arsenite results in decreased expression of CASP2 mRNA CTD PMID:12760830 sodium arsenite increases cleavage ISO RGD:1604850 6480464 sodium arsenite results in increased cleavage of CASP2 protein CTD PMID:21642427 sodium chloride increases expression ISO RGD:1604850 6480464 Sodium Chloride results in increased expression of CASP2 mRNA CTD PMID:23634900 sodium cyanate multiple interactions ISO RGD:1604850 6480464 [sodium cyanate co-treated with Hydrogen Peroxide] results in increased activity of CASP2 protein CTD PMID:28400100 sodium cyanate increases activity ISO RGD:1604850 6480464 sodium cyanate results in increased activity of CASP2 protein CTD PMID:28400100 sodium dichromate increases expression ISO RGD:731460 6480464 sodium bichromate results in increased expression of CASP2 mRNA CTD PMID:31558096 staurosporine increases cleavage ISO RGD:1604850 6480464 Staurosporine results in increased cleavage of CASP2 protein CTD PMID:10663630 , PMID:26124276 tamoxifen affects expression ISO RGD:731460 6480464 Tamoxifen affects the expression of CASP2 mRNA CTD PMID:17555576 tauroursodeoxycholic acid multiple interactions ISO RGD:1604850 6480464 ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased activity of CASP2 protein], ursodoxicoltaurine inhibits the reaction [APP gene mutant form results in increased activity of CASP2 protein] CTD PMID:16923170 Terfenadine increases activity ISO RGD:1604850 6480464 Terfenadine results in increased activity of CASP2 protein CTD PMID:16569656 testosterone increases expression ISO RGD:731460 6480464 Testosterone deficiency results in increased expression of CASP2 mRNA CTD PMID:33848595 tetrachloromethane increases expression ISO RGD:731460 6480464 Carbon Tetrachloride results in increased expression of CASP2 mRNA CTD PMID:15056808 , PMID:31919559 thapsigargin multiple interactions ISO RGD:1604850 6480464 Diclofenac inhibits the reaction [Thapsigargin results in increased activity of CASP2 protein] CTD PMID:16388830 thapsigargin increases activity ISO RGD:1604850 6480464 Thapsigargin results in increased activity of CASP2 protein CTD PMID:16388830 theophylline multiple interactions ISO RGD:1604850 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of CASP2 protein CTD PMID:18951874 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of CASP2 mRNA CTD PMID:23411599 , PMID:34492290 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of CASP2 mRNA CTD PMID:25729387 topotecan multiple interactions ISO RGD:1604850 6480464 benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Topotecan results in increased cleavage of CASP2 protein] more ... CTD PMID:19812371 topotecan increases cleavage ISO RGD:1604850 6480464 Topotecan results in increased cleavage of CASP2 protein CTD PMID:19812371 topotecan multiple interactions ISO RGD:731460 6480464 APAF1 promotes the reaction [Topotecan results in increased cleavage of CASP2 protein] more ... CTD PMID:19812371 topotecan increases cleavage ISO RGD:731460 6480464 Topotecan results in increased cleavage of CASP2 protein CTD PMID:19812371 Tributyltin oxide decreases expression EXP 6480464 bis(tri-n-butyltin)oxide results in decreased expression of CASP2 mRNA CTD PMID:17553608 tunicamycin multiple interactions ISO RGD:1604850 6480464 Diclofenac inhibits the reaction [Tunicamycin results in increased activity of CASP2 protein] CTD PMID:16388830 tunicamycin decreases expression ISO RGD:1604850 6480464 Tunicamycin results in decreased expression of CASP2 mRNA CTD PMID:22378314 tunicamycin increases activity ISO RGD:1604850 6480464 Tunicamycin results in increased activity of CASP2 protein CTD PMID:16388830 undecane decreases expression EXP 6480464 undecane results in decreased expression of CASP2 protein CTD PMID:17337753 urethane increases expression EXP 6480464 Urethane results in increased expression of CASP2 mRNA CTD PMID:16978161 valproic acid affects expression ISO RGD:1604850 6480464 Valproic Acid affects the expression of CASP2 mRNA CTD PMID:25979313 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of CASP2 mRNA CTD PMID:23034163 violacein increases activity ISO RGD:731460 6480464 violacein results in increased activity of CASP2 protein CTD PMID:20416285 vorinostat increases cleavage ISO RGD:1604850 6480464 vorinostat results in increased cleavage of CASP2 protein CTD PMID:15897598 zoledronic acid affects expression ISO RGD:1604850 6480464 zoledronic acid affects the expression of CASP2 mRNA CTD PMID:19036117
