(-)-epigallocatechin 3-gallate multiple interactions ISO MMP1 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of MMP1 mRNA and epigallocatechin gallate inhibits the reaction [Particulate Matter results in increased expression of MMP1 protein] CTD PMID:22079256 and PMID:31252129 (S)-nicotine increases expression ISO MMP1 (Homo sapiens) 6480464 Nicotine results in increased expression of MMP1 mRNA and Nicotine results in increased expression of MMP1 protein CTD PMID:17151781 and PMID:18986645 (S)-nicotine multiple interactions ISO MMP1 (Homo sapiens) 6480464 lipopolysaccharide more ... CTD PMID:17151781 and PMID:18986645 1-chloro-2,4-dinitrobenzene increases expression ISO MMP1 (Homo sapiens) 6480464 Dinitrochlorobenzene results in increased expression of MMP1 mRNA CTD PMID:20146380 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO MMP1 (Homo sapiens) 6480464 15-deoxy-delta(12 more ... CTD PMID:19136476 15-deoxy-Delta(12,14)-prostaglandin J2 increases expression ISO MMP1 (Homo sapiens) 6480464 15-deoxy-delta(12 and 14)-prostaglandin J2 results in increased expression of MMP1 mRNA CTD PMID:19136476 17beta-estradiol multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of MMP1 mRNA more ... CTD PMID:17157789 more ... 17beta-estradiol decreases expression ISO MMP1 (Homo sapiens) 6480464 Estradiol results in decreased expression of MMP1 mRNA CTD PMID:21795739 17beta-estradiol increases expression ISO MMP1 (Homo sapiens) 6480464 Estradiol results in increased expression of MMP1 mRNA CTD PMID:20106945 and PMID:32844545 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO MMP1 (Homo sapiens) 6480464 Metribolone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA] CTD PMID:8798622 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO MMP1 (Homo sapiens) 6480464 Dihydrotestosterone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA] CTD PMID:8798622 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO MMP1 (Homo sapiens) 6480464 2 more ... CTD PMID:30202865 more ... 2,2',4,4'-Tetrabromodiphenyl ether increases secretion ISO MMP1 (Homo sapiens) 6480464 2 more ... CTD PMID:32142752 2,2',5,5'-tetrachlorobiphenyl increases expression ISO MMP1 (Homo sapiens) 6480464 2 more ... CTD PMID:36804509 2,2',5,5'-tetrachlorobiphenyl decreases expression ISO MMP1 (Homo sapiens) 6480464 2 more ... CTD PMID:36804509 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO MMP1 (Homo sapiens) 6480464 1 more ... CTD PMID:15075337 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO MMP1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of MMP1 more ... CTD PMID:12377990 more ... 2,4,6-tribromophenol increases expression ISO MMP1 (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 2,4,6-trinitrobenzenesulfonic acid increases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA and Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein CTD PMID:18837084 2,4,6-trinitrobenzenesulfonic acid multiple interactions EXP 6480464 ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein] and ilomastat inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA] CTD PMID:18837084 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO MMP1 (Homo sapiens) 6480464 2 more ... CTD PMID:26705709 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO MMP1 (Homo sapiens) 6480464 Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1] more ... CTD PMID:15144122 more ... 2-hydroxypropanoic acid affects expression ISO MMP1 (Homo sapiens) 6480464 Lactic Acid affects the expression of MMP1 mRNA CTD PMID:30851411 2-palmitoylglycerol increases expression ISO MMP1 (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of MMP1 mRNA CTD PMID:37199045 2-trans,6-trans,10-trans-geranylgeranyl diphosphate multiple interactions ISO MMP1 (Homo sapiens) 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP1]] more ... CTD PMID:17303772 and PMID:18625914 3,3',4,4',5-pentachlorobiphenyl increases expression ISO MMP1 (Homo sapiens) 6480464 3 more ... CTD PMID:35618242 3,3',5,5'-tetrabromobisphenol A increases expression ISO MMP1 (Homo sapiens) 6480464 tetrabromobisphenol A results in increased expression of MMP1 protein CTD PMID:31675489 3,4-dichloroaniline increases expression ISO MMP1 (Homo sapiens) 6480464 3 and 4-dichloroaniline results in increased expression of MMP1 mRNA CTD PMID:24172598 3-hydroxypicolinic acid decreases activity ISO MMP1 (Homo sapiens) 6480464 3-hydroxypicolinic acid results in decreased activity of MMP1 protein CTD PMID:21189019 3-methylcholanthrene increases expression ISO Mmp1b (Mus musculus) 6480464 Methylcholanthrene results in increased expression of MMP1 mRNA CTD PMID:29554273 4-hydroxynon-2-enal increases activity ISO MMP1 (Homo sapiens) 6480464 4-hydroxy-2-nonenal results in increased activity of MMP1 protein CTD PMID:14672615 4-hydroxynon-2-enal increases expression ISO MMP1 (Homo sapiens) 6480464 4-hydroxy-2-nonenal results in increased expression of MMP1 mRNA CTD PMID:14672615 5-aminolevulinic acid affects expression ISO MMP1 (Homo sapiens) 6480464 Aminolevulinic Acid affects the expression of MMP1 mRNA and Aminolevulinic Acid affects the expression of MMP1 protein CTD PMID:12542540 5-aminolevulinic acid multiple interactions ISO MMP1 (Homo sapiens) 6480464 Sodium Azide inhibits the reaction [Aminolevulinic Acid affects the expression of MMP1 protein] CTD PMID:12542540 5-aza-2'-deoxycytidine affects expression ISO MMP1 (Homo sapiens) 6480464 Decitabine affects the expression of MMP1 mRNA CTD PMID:17145863 5-azacytidine increases expression ISO MMP1 (Homo sapiens) 6480464 Azacitidine results in increased expression of MMP1 mRNA CTD PMID:20823114 5-fluorouracil multiple interactions ISO MMP1 (Homo sapiens) 6480464 TP53 protein affects the reaction [Fluorouracil results in decreased expression of MMP1 mRNA] CTD PMID:15016801 5-fluorouracil increases expression ISO MMP1 (Homo sapiens) 6480464 Fluorouracil results in increased expression of MMP1 mRNA CTD PMID:19528421 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO MMP1 (Homo sapiens) 6480464 6-chloro-2 more ... CTD PMID:20426787 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide increases expression ISO MMP1 (Homo sapiens) 6480464 6-chloro-2 more ... CTD PMID:20426787 acetaldehyde decreases expression ISO MMP1 (Homo sapiens) 6480464 Acetaldehyde results in decreased expression of MMP1 mRNA CTD PMID:7934638 acrolein increases secretion ISO MMP1 (Homo sapiens) 6480464 Acrolein results in increased secretion of MMP1 protein CTD PMID:21742783 acrolein increases expression ISO MMP1 (Homo sapiens) 6480464 Acrolein results in increased expression of MMP1 mRNA CTD PMID:21742783 actinomycin D multiple interactions ISO MMP1 (Homo sapiens) 6480464 Dactinomycin inhibits the reaction [15-deoxy-delta(12 and 14)-prostaglandin J2 results in increased expression of MMP1 protein] CTD PMID:19136476 aflatoxin M1 decreases expression ISO MMP1 (Homo sapiens) 6480464 Aflatoxin M1 results in decreased expression of MMP1 mRNA CTD PMID:30928695 aldehydo-D-glucosamine multiple interactions ISO MMP1 (Homo sapiens) 6480464 Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1] more ... CTD PMID:15144122 more ... aldehydo-D-glucose multiple interactions ISO MMP1 (Homo sapiens) 6480464 CD14 protein affects the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]] CTD PMID:18180316 aldehydo-D-glucose multiple interactions ISO Mmp1b (Mus musculus) 6480464 Glucose inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA] and Glucose inhibits the reaction [IL1B protein results in increased expression of MMP1 protein] CTD PMID:30098273 aldehydo-D-glucose decreases expression ISO MMP1 (Homo sapiens) 6480464 Glucose results in decreased expression of MMP1 mRNA CTD PMID:31655124 all-trans-retinoic acid multiple interactions ISO MMP1 (Homo sapiens) 6480464 AHR protein promotes the reaction [Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]] more ... CTD PMID:15075337 and PMID:16176868 all-trans-retinoic acid decreases expression ISO MMP1 (Homo sapiens) 6480464 Tretinoin results in decreased expression of MMP1 mRNA CTD PMID:16467367 all-trans-retinoic acid decreases degradation ISO MMP1 (Homo sapiens) 6480464 Tretinoin results in decreased degradation of MMP1 mRNA CTD PMID:15075337 alpha-naphthoflavone multiple interactions EXP 6480464 alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP1 mRNA] CTD PMID:19022365 alpha-naphthoflavone multiple interactions ISO MMP1 (Homo sapiens) 6480464 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA] and alpha-naphthoflavone inhibits the reaction [Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]] CTD PMID:15075337 aluminium oxide increases expression ISO MMP1 (Homo sapiens) 6480464 Aluminum Oxide results in increased expression of MMP1 mRNA CTD PMID:16488289 amitrole multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Amitrole co-treated with SOD2 protein] results in increased expression of MMP1 mRNA and Deferoxamine inhibits the reaction [[Amitrole co-treated with SOD2 protein] results in increased expression of MMP1 mRNA] CTD PMID:10464329 Ammothamnine multiple interactions ISO MMP1 (Homo sapiens) 6480464 oxymatrine analog inhibits the reaction [TNF protein results in increased expression of MMP1 protein] CTD PMID:34459104 anandamide increases expression ISO MMP1 (Homo sapiens) 6480464 anandamide results in increased expression of MMP1 mRNA CTD PMID:16330497 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO MMP1 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of and results in increased activity of MMP1 protein] more ... CTD PMID:12832416 more ... apigenin decreases expression ISO MMP1 (Homo sapiens) 6480464 Apigenin results in decreased expression of MMP1 mRNA and Apigenin results in decreased expression of MMP1 protein CTD PMID:21112745 Arg-Gly-Asp increases expression ISO MMP1 (Homo sapiens) 6480464 arginyl-glycyl-aspartic acid results in increased expression of MMP1 CTD PMID:15547672 arotinoid acid multiple interactions ISO MMP1 (Homo sapiens) 6480464 [4-(2-(5 more ... CTD PMID:34480604 arsane increases expression ISO MMP1 (Homo sapiens) 6480464 Arsenic results in increased expression of MMP1 mRNA CTD PMID:12928151 arsenic atom increases expression ISO MMP1 (Homo sapiens) 6480464 Arsenic results in increased expression of MMP1 mRNA CTD PMID:12928151 arsenous acid decreases expression ISO MMP1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of MMP1 mRNA CTD PMID:15761015 and PMID:23253724 arsenous acid multiple interactions ISO MMP1 (Homo sapiens) 6480464 [acetyl-11-ketoboswellic acid co-treated with Arsenic Trioxide] results in decreased activity of MMP1 protein more ... CTD PMID:21078271 and PMID:23253724 Azaspiracid increases expression ISO MMP1 (Homo sapiens) 6480464 azaspiracid results in increased expression of MMP1 mRNA CTD PMID:28939011 azithromycin increases secretion ISO MMP1 (Homo sapiens) 6480464 Azithromycin results in increased secretion of MMP1 protein CTD PMID:24890593 azithromycin decreases secretion ISO MMP1 (Homo sapiens) 6480464 Azithromycin results in decreased secretion of MMP1 protein CTD PMID:24890593 benzo[a]pyrene multiple interactions EXP 6480464 alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP1 mRNA] CTD PMID:19022365 benzo[a]pyrene affects methylation ISO MMP1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of MMP1 promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO MMP1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of MMP1 mRNA and Benzo(a)pyrene results in increased expression of MMP1 protein CTD PMID:15808406 more ... benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of MMP1 mRNA CTD PMID:19022365 benzo[a]pyrene diol epoxide I increases expression ISO MMP1 (Homo sapiens) 6480464 7 more ... CTD PMID:20382639 Benzo[k]fluoranthene multiple interactions ISO MMP1 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of MMP1 mRNA] and SB 203580 inhibits the reaction [benzo(k)fluoranthene results in increased expression of MMP1 mRNA] CTD PMID:21635667 Benzo[k]fluoranthene increases expression ISO MMP1 (Homo sapiens) 6480464 benzo(k)fluoranthene results in increased expression of MMP1 mRNA CTD PMID:21635667 benzylpenicillin decreases expression ISO MMP1 (Homo sapiens) 6480464 Penicillin G results in decreased expression of MMP1 mRNA CTD PMID:24737281 beta-D-glucosamine multiple interactions ISO MMP1 (Homo sapiens) 6480464 Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1] more ... CTD PMID:15144122 more ... bexarotene decreases expression ISO MMP1 (Homo sapiens) 6480464 bexarotene results in decreased expression of MMP1 mRNA CTD PMID:17178900 Bis-(1-chloro-2-propyl) phosphate multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Flame Retardants results in increased abundance of bis(1-chloro-2-propyl)phosphate] which affects the expression of MMP1 protein CTD PMID:33677611 bisphenol A multiple interactions ISO MMP1 (Homo sapiens) 6480464 bisphenol A inhibits the reaction [Estradiol inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]] CTD PMID:20600708 bisphenol A decreases expression ISO MMP1 (Homo sapiens) 6480464 bisphenol A results in decreased expression of MMP1 mRNA CTD PMID:36232920 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of MMP1 mRNA and bisphenol A results in decreased expression of MMP1B mRNA CTD PMID:25181051 bleomycin A2 increases expression ISO MMP1 (Homo sapiens) 6480464 Bleomycin results in increased expression of MMP1 mRNA and Bleomycin results in increased expression of MMP1 protein CTD PMID:18684396 bufalin decreases expression ISO MMP1 (Homo sapiens) 6480464 bufalin results in decreased expression of MMP1 protein CTD PMID:23949904 butanal increases expression ISO MMP1 (Homo sapiens) 6480464 butyraldehyde results in increased expression of MMP1 mRNA CTD PMID:26079696 cadmium atom increases expression ISO MMP1 (Homo sapiens) 6480464 Cadmium results in increased expression of MMP1 mRNA CTD PMID:22562489 cadmium dichloride multiple interactions ISO MMP1 (Homo sapiens) 6480464 Cadmium Chloride inhibits the reaction [Oxygen deficiency results in decreased expression of MMP1 mRNA] CTD PMID:20193091 cadmium dichloride increases secretion ISO MMP1 (Homo sapiens) 6480464 Cadmium Chloride results in increased secretion of MMP1 protein CTD PMID:30572105 cadmium dichloride decreases expression ISO MMP1 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of MMP1 mRNA CTD PMID:26472689 calcitriol increases expression ISO MMP1 (Homo sapiens) 6480464 Calcitriol results in increased expression of MMP1 mRNA CTD PMID:12040012 and PMID:16002434 calcium atom affects expression ISO MMP1 (Homo sapiens) 6480464 Calcium affects the expression of MMP1 mRNA and Calcium affects the expression of MMP1 protein CTD PMID:17508023 calcium(0) affects expression ISO MMP1 (Homo sapiens) 6480464 Calcium affects the expression of MMP1 mRNA and Calcium affects the expression of MMP1 protein CTD PMID:17508023 cannabidiol increases expression ISO MMP1 (Homo sapiens) 6480464 Cannabidiol results in increased expression of MMP1 mRNA CTD PMID:36519830 capsaicin increases expression ISO MMP1 (Homo sapiens) 6480464 Capsaicin results in increased expression of MMP1 mRNA and Capsaicin results in increased expression of MMP1 protein CTD PMID:17508023 and PMID:21310942 capsaicin multiple interactions ISO MMP1 (Homo sapiens) 6480464 capsazepine inhibits the reaction [Capsaicin results in increased expression of MMP1 protein] CTD PMID:17508023 capsazepine multiple interactions ISO MMP1 (Homo sapiens) 6480464 capsazepine inhibits the reaction [Capsaicin results in increased expression of MMP1 protein] CTD PMID:17508023 capsazepine affects expression ISO MMP1 (Homo sapiens) 6480464 capsazepine affects the expression of MMP1 mRNA and capsazepine affects the expression of MMP1 protein CTD PMID:17508023 carazolol multiple interactions ISO MMP1 (Homo sapiens) 6480464 carazolol inhibits the reaction [[Particulate Matter co-treated with Methylene Chloride] results in increased expression of MMP1 mRNA] CTD PMID:30503853 carbamazepine affects expression ISO MMP1 (Homo sapiens) 6480464 Carbamazepine affects the expression of MMP1 mRNA CTD PMID:25979313 CGP 52608 multiple interactions ISO MMP1 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to MMP1 gene] CTD PMID:28238834 chalcones decreases expression ISO MMP1 (Homo sapiens) 6480464 Chalcones analog results in decreased expression of MMP1 mRNA CTD PMID:32856275 CHIR 99021 multiple interactions ISO MMP1 (Homo sapiens) 6480464 [4-(2-(5 more ... CTD PMID:34480604 chloropicrin increases expression ISO MMP1 (Homo sapiens) 6480464 chloropicrin results in increased expression of MMP1 mRNA CTD PMID:26352163 and PMID:28476498 chlorothalonil decreases expression ISO MMP1 (Homo sapiens) 6480464 tetrachloroisophthalonitrile metabolite results in decreased expression of MMP1 mRNA CTD PMID:32289622 chromium atom multiple interactions ISO MMP1 (Homo sapiens) 6480464 Genistein inhibits the reaction [Chromium results in increased expression of MMP1 mRNA] and herbimycin inhibits the reaction [Chromium results in increased expression of MMP1 mRNA] CTD PMID:15878362 chromium atom increases expression ISO MMP1 (Homo sapiens) 6480464 Chromium results in increased expression of MMP1 mRNA CTD PMID:15878362 chrysin decreases expression ISO MMP1 (Homo sapiens) 6480464 chrysin results in decreased expression of MMP1 protein CTD PMID:30578657 ciprofloxacin multiple interactions ISO MMP1 (Homo sapiens) 6480464 Ciprofloxacin promotes the reaction [IL1B protein results in increased expression of MMP1 mRNA] and Ciprofloxacin promotes the reaction [IL1B protein results in increased secretion of MMP1 protein] CTD PMID:12428247 and PMID:16148020 ciprofloxacin increases expression ISO MMP1 (Homo sapiens) 6480464 Ciprofloxacin results in increased expression of MMP1 mRNA CTD PMID:12428247 cisplatin multiple interactions ISO MMP1 (Homo sapiens) 6480464 6-hydroxy-2 more ... CTD PMID:20705681 and PMID:37497868 cisplatin increases expression ISO MMP1 (Homo sapiens) 6480464 Cisplatin results in increased expression of MMP1 protein CTD PMID:37497868 cobalt atom multiple interactions ISO MMP1 (Homo sapiens) 6480464 [tungsten carbide binds to Cobalt] which results in decreased expression of MMP1 mRNA more ... CTD PMID:15878362 and PMID:20105288 cobalt atom increases expression ISO MMP1 (Homo sapiens) 6480464 Cobalt results in increased expression of MMP1 mRNA CTD PMID:15878362 cobalt dichloride decreases expression ISO MMP1 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of MMP1 mRNA CTD PMID:20105288 copper atom multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Organoselenium Compounds binds to Copper] which results in increased expression of MMP1 mRNA CTD PMID:25167922 copper(0) multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Organoselenium Compounds binds to Copper] which results in increased expression of MMP1 mRNA CTD PMID:25167922 copper(II) sulfate increases expression ISO MMP1 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of MMP1 mRNA CTD PMID:19549813 cordycepin multiple interactions ISO MMP1 (Homo sapiens) 6480464 cordycepin inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA] and cordycepin inhibits the reaction [IL1B protein results in increased expression of MMP1 protein] CTD PMID:19056796 cortisol multiple interactions ISO MMP1 (Homo sapiens) 6480464 [4-(2-(5 more ... CTD PMID:34480604 crocidolite asbestos increases expression ISO MMP1 (Homo sapiens) 6480464 Asbestos more ... CTD PMID:16966607 more ... Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of MMP1 mRNA CTD PMID:27523638 curcumin multiple interactions ISO Mmp1b (Mus musculus) 6480464 Curcumin inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA] CTD PMID:30098273 cycloheximide multiple interactions ISO MMP1 (Homo sapiens) 6480464 Cycloheximide inhibits the reaction [15-deoxy-delta(12 more ... CTD PMID:15075337 and PMID:19136476 cyclosporin A increases expression ISO MMP1 (Homo sapiens) 6480464 Cyclosporine results in increased expression of MMP1 mRNA CTD PMID:10914799 and PMID:20106945 cyclosporin A decreases expression ISO MMP1 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of MMP1 mRNA CTD PMID:22147139 and PMID:34681664 D-glucose multiple interactions ISO MMP1 (Homo sapiens) 6480464 CD14 protein affects the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]] CTD PMID:18180316 D-glucose multiple interactions ISO Mmp1b (Mus musculus) 6480464 Glucose inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA] and Glucose inhibits the reaction [IL1B protein results in increased expression of MMP1 protein] CTD PMID:30098273 D-glucose decreases expression ISO MMP1 (Homo sapiens) 6480464 Glucose results in decreased expression of MMP1 mRNA CTD PMID:31655124 deguelin decreases expression ISO MMP1 (Homo sapiens) 6480464 deguelin results in decreased expression of MMP1 protein CTD PMID:25322282 desferrioxamine B multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Deferoxamine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA more ... CTD PMID:10464329 and PMID:19136476 dexamethasone multiple interactions ISO MMP1 (Homo sapiens) 6480464 Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA] and Mifepristone inhibits the reaction [Dexamethasone results in decreased secretion of MMP1 protein] CTD PMID:15698539 and PMID:20858459 dexamethasone decreases expression ISO MMP1 (Homo sapiens) 6480464 Dexamethasone results in decreased expression of MMP1 mRNA CTD PMID:25047013 dexamethasone decreases secretion ISO MMP1 (Homo sapiens) 6480464 Dexamethasone results in decreased secretion of MMP1 protein CTD PMID:15698539 diarsenic trioxide decreases expression ISO MMP1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of MMP1 mRNA CTD PMID:15761015 and PMID:23253724 diarsenic trioxide multiple interactions ISO MMP1 (Homo sapiens) 6480464 [acetyl-11-ketoboswellic acid co-treated with Arsenic Trioxide] results in decreased activity of MMP1 protein more ... CTD PMID:21078271 and PMID:23253724 dibenziodolium multiple interactions ISO MMP1 (Homo sapiens) 6480464 diphenyleneiodonium inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA] and diphenyleneiodonium inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA] CTD PMID:17449795 dichloromethane multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Particulate Matter co-treated with Methylene Chloride] results in increased expression of MMP1 mRNA and carazolol inhibits the reaction [[Particulate Matter co-treated with Methylene Chloride] results in increased expression of MMP1 mRNA] CTD PMID:30503853 Didecyldimethylammonium multiple interactions ISO MMP1 (Homo sapiens) 6480464 didecyldimethylammonium results in increased expression of and results in increased secretion of MMP1 protein CTD PMID:32763356 Didecyldimethylammonium increases expression ISO MMP1 (Homo sapiens) 6480464 didecyldimethylammonium results in increased expression of MMP1 mRNA CTD PMID:32763356 dieckol decreases expression ISO MMP1 (Homo sapiens) 6480464 dieckol results in decreased expression of MMP1 mRNA and dieckol results in decreased expression of MMP1 protein CTD PMID:19330880 dieckol multiple interactions ISO MMP1 (Homo sapiens) 6480464 dieckol inhibits the reaction [Particulate Matter results in increased expression of MMP1 protein] CTD PMID:33164846 diethyl maleate increases expression ISO MMP1 (Homo sapiens) 6480464 diethyl maleate results in increased expression of MMP1 mRNA CTD PMID:33545341 dimethyl sulfoxide increases expression ISO MMP1 (Homo sapiens) 6480464 Dimethyl Sulfoxide results in increased expression of MMP1 mRNA and Dimethyl Sulfoxide results in increased expression of MMP1 protein CTD PMID:18684396 dimethylarsinous acid increases expression ISO MMP1 (Homo sapiens) 6480464 dimethylarsinous acid results in increased expression of MMP1 mRNA CTD PMID:23487506 and PMID:23876855 dinophysistoxin 1 increases expression ISO MMP1 (Homo sapiens) 6480464 dinophysistoxin 1 results in increased expression of MMP1 mRNA CTD PMID:28939011 dioxygen multiple interactions ISO MMP1 (Homo sapiens) 6480464 Cadmium Chloride inhibits the reaction [Oxygen deficiency results in decreased expression of MMP1 mRNA] CTD PMID:20193091 dioxygen decreases expression ISO MMP1 (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of MMP1 mRNA and Oxygen deficiency results in decreased expression of MMP1 protein CTD PMID:20193091 diuron increases expression ISO MMP1 (Homo sapiens) 6480464 Diuron metabolite results in increased expression of MMP1 mRNA CTD PMID:24172598 dizocilpine maleate multiple interactions EXP 6480464 Dizocilpine Maleate inhibits the reaction [Folic Acid deficiency results in decreased expression of MMP1 mRNA] and Dizocilpine Maleate inhibits the reaction [Homocysteine analog results in decreased expression of and results in decreased activity of MMP1 protein] CTD PMID:20406136 doxorubicin affects response to substance ISO MMP1 (Homo sapiens) 6480464 MMP1 protein affects the susceptibility to Doxorubicin CTD PMID:16217747 doxorubicin decreases expression ISO MMP1 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of MMP1 mRNA CTD PMID:29803840 doxorubicin decreases response to substance ISO MMP1 (Homo sapiens) 6480464 MMP1 protein results in decreased susceptibility to Doxorubicin CTD PMID:11313874 EC 3.1.1.4 (phospholipase A2) inhibitor multiple interactions ISO MMP1 (Homo sapiens) 6480464 Phospholipase A2 Inhibitors inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA] and Phospholipase A2 Inhibitors inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein] CTD PMID:19765281 EC 3.1.1.4 (phospholipase A2) inhibitor decreases expression ISO MMP1 (Homo sapiens) 6480464 Phospholipase A2 Inhibitors results in decreased expression of MMP1 mRNA CTD PMID:19765281 endosulfan increases expression ISO MMP1 (Homo sapiens) 6480464 Endosulfan results in increased expression of MMP1 mRNA CTD PMID:30090376 ethanol increases expression ISO Mmp1b (Mus musculus) 6480464 Ethanol results in increased expression of MMP1B mRNA CTD PMID:37271273 ethanol multiple interactions ISO Mmp1b (Mus musculus) 6480464 [Palmitic Acid co-treated with Ethanol] results in increased expression of MMP1B mRNA CTD PMID:37271273 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO MMP1 (Homo sapiens) 6480464 Egtazic Acid inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA] and Egtazic Acid inhibits the reaction [Vehicle Emissions results in increased secretion of MMP1 protein] CTD PMID:21245013 etoposide decreases expression ISO MMP1 (Homo sapiens) 6480464 Etoposide results in decreased expression of MMP1 protein CTD PMID:18557930 etoposide multiple interactions ISO MMP1 (Homo sapiens) 6480464 pifithrin inhibits the reaction [Etoposide results in decreased expression of MMP1 protein] CTD PMID:18557930 famotidine multiple interactions ISO MMP1 (Homo sapiens) 6480464 Famotidine inhibits the reaction [Histamine results in increased expression of MMP1 mRNA] and Famotidine inhibits the reaction [Histamine results in increased secretion of MMP1 protein] CTD PMID:17656145 fenofibrate decreases expression ISO MMP1 (Homo sapiens) 6480464 Fenofibrate results in decreased expression of MMP1 protein CTD PMID:25545733 flavonoids multiple interactions EXP 6480464 Flavonoids inhibits the reaction [Dimethylnitrosamine results in increased expression of MMP1 mRNA] CTD PMID:16270385 folic acid decreases activity EXP 6480464 Folic Acid deficiency results in decreased activity of MMP1 protein CTD PMID:20406136 folic acid multiple interactions EXP 6480464 Dizocilpine Maleate inhibits the reaction [Folic Acid deficiency results in decreased expression of MMP1 mRNA] CTD PMID:20406136 folic acid decreases expression EXP 6480464 Folic Acid deficiency results in decreased expression of MMP1 mRNA CTD PMID:20406136 formaldehyde multiple interactions ISO MMP1 (Homo sapiens) 6480464 Cystathionine inhibits the reaction [Formaldehyde results in increased expression of MMP1 protein] and Cysteine inhibits the reaction [Formaldehyde results in increased expression of MMP1 protein] CTD PMID:27664576 formaldehyde decreases expression ISO MMP1 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of MMP1 mRNA CTD PMID:28937961 formaldehyde increases expression ISO MMP1 (Homo sapiens) 6480464 Formaldehyde results in increased expression of MMP1 mRNA and Formaldehyde results in increased expression of MMP1 protein CTD PMID:27664576 fulvestrant multiple interactions ISO MMP1 (Homo sapiens) 6480464 fulvestrant inhibits the reaction [Estradiol inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]] CTD PMID:20600708 gadodiamide hydrate increases expression ISO MMP1 (Homo sapiens) 6480464 gadodiamide results in increased expression of MMP1 mRNA and gadodiamide results in increased expression of MMP1 protein CTD PMID:19561517 gadodiamide hydrate multiple interactions ISO MMP1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased expression of MMP1 protein] and U 0126 inhibits the reaction [gadodiamide results in increased expression of MMP1 protein] CTD PMID:19561517 geldanamycin multiple interactions ISO MMP1 (Homo sapiens) 6480464 [geldanamycin co-treated with PTHLH protein modified form] results in increased expression of MMP1 mRNA CTD PMID:12724357 geldanamycin decreases expression ISO MMP1 (Homo sapiens) 6480464 geldanamycin results in decreased expression of MMP1 mRNA CTD PMID:26705709 genistein multiple interactions ISO MMP1 (Homo sapiens) 6480464 Genistein inhibits the reaction [Chromium results in increased expression of MMP1 mRNA] more ... CTD PMID:15878362 genistein decreases expression ISO MMP1 (Homo sapiens) 6480464 Genistein results in decreased expression of MMP1 mRNA CTD PMID:22228119 glucose multiple interactions ISO MMP1 (Homo sapiens) 6480464 CD14 protein affects the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]] CTD PMID:18180316 glucose multiple interactions ISO Mmp1b (Mus musculus) 6480464 Glucose inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA] and Glucose inhibits the reaction [IL1B protein results in increased expression of MMP1 protein] CTD PMID:30098273 glucose decreases expression ISO MMP1 (Homo sapiens) 6480464 Glucose results in decreased expression of MMP1 mRNA CTD PMID:31655124 Heliotrine increases expression ISO MMP1 (Homo sapiens) 6480464 heliotrine results in increased expression of MMP1 mRNA CTD PMID:26100227 hemin increases expression ISO MMP1 (Homo sapiens) 6480464 Hemin results in increased expression of MMP1 protein CTD PMID:19136476 heparin decreases activity ISO MMP1 (Homo sapiens) 6480464 Heparin results in decreased activity of MMP1 protein CTD PMID:10958381 herbimycin multiple interactions ISO MMP1 (Homo sapiens) 6480464 herbimycin inhibits the reaction [Chromium results in increased expression of MMP1 mRNA] more ... CTD PMID:15878362 hexadecanoic acid increases expression ISO Mmp1b (Mus musculus) 6480464 Palmitic Acid results in increased expression of MMP1B mRNA CTD PMID:37271273 hexadecanoic acid multiple interactions ISO Mmp1b (Mus musculus) 6480464 [Palmitic Acid co-treated with Ethanol] results in increased expression of MMP1B mRNA CTD PMID:37271273 histamine multiple interactions ISO MMP1 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Histamine results in increased expression of MMP1 mRNA] more ... CTD PMID:17656145 histamine increases expression ISO MMP1 (Homo sapiens) 6480464 Histamine results in increased expression of MMP1 mRNA CTD PMID:17656145 and PMID:9856766 histamine increases secretion ISO MMP1 (Homo sapiens) 6480464 Histamine results in increased secretion of MMP1 protein CTD PMID:17656145 homocysteine multiple interactions EXP 6480464 Dizocilpine Maleate inhibits the reaction [Homocysteine analog results in decreased expression of and results in decreased activity of MMP1 protein] and Homocysteine analog results in decreased expression of and results in decreased activity of MMP1 protein CTD PMID:20406136 HU-308 multiple interactions ISO MMP1 (Homo sapiens) 6480464 HU 308 inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA] and HU 308 inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA] CTD PMID:34537380 hyaluronic acid multiple interactions ISO Mmp1b (Mus musculus) 6480464 [Hyaluronic Acid co-treated with Resveratrol] results in decreased expression of MMP1 mRNA CTD PMID:23595953 hydrogen chloride increases expression EXP 6480464 Hydrochloric Acid results in increased expression of MMP1 protein CTD PMID:11850527 hydrogen peroxide affects expression ISO MMP1 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of MMP1 mRNA CTD PMID:20044591 hydrogen peroxide multiple interactions ISO MMP1 (Homo sapiens) 6480464 Hydrogen Peroxide inhibits the reaction [ursonic acid results in decreased expression of MMP1 mRNA] and loliolide inhibits the reaction [Hydrogen Peroxide results in increased expression of MMP1 mRNA] CTD PMID:30231594 and PMID:31790661 hydrogen peroxide increases expression ISO MMP1 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of MMP1 mRNA and Hydrogen Peroxide results in increased expression of MMP1 protein CTD PMID:22580338 and PMID:30231594 hydroquinone increases expression ISO MMP1 (Homo sapiens) 6480464 hydroquinone results in increased expression of MMP1 mRNA CTD PMID:31256213 hydroxychloroquine multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Hydroxychloroquine co-treated with Methotrexate co-treated with Sulfasalazine] results in decreased expression of MMP1 mRNA CTD PMID:28863153 ibuprofen increases expression ISO MMP1 (Homo sapiens) 6480464 Ibuprofen results in increased expression of MMP1 mRNA CTD PMID:16580899 ilomastat multiple interactions EXP 6480464 ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein] and ilomastat inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA] CTD PMID:18837084 iron atom multiple interactions ISO MMP1 (Homo sapiens) 6480464 [[15-deoxy-delta(12 more ... CTD PMID:19136476 iron(0) multiple interactions ISO MMP1 (Homo sapiens) 6480464 [[15-deoxy-delta(12 more ... CTD PMID:19136476 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of MMP1 CTD PMID:12883319 isoprenaline multiple interactions EXP 6480464 SI 27 inhibits the reaction [Isoproterenol results in increased expression of MMP1] CTD PMID:12883319 L-ascorbic acid multiple interactions ISO MMP1 (Homo sapiens) 6480464 [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MMP1 mRNA and Ascorbic Acid inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MMP1 mRNA] CTD PMID:10836612 and PMID:34480604 L-ascorbic acid 2-phosphate multiple interactions ISO MMP1 (Homo sapiens) 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MMP1 mRNA CTD PMID:34480604 L-cystathionine multiple interactions ISO MMP1 (Homo sapiens) 6480464 Cystathionine inhibits the reaction [Formaldehyde results in increased expression of MMP1 protein] CTD PMID:27664576 L-cysteine multiple interactions ISO MMP1 (Homo sapiens) 6480464 Cysteine inhibits the reaction [Formaldehyde results in increased expression of MMP1 protein] CTD PMID:27664576 lamivudine increases expression ISO MMP1 (Homo sapiens) 6480464 Lamivudine results in increased expression of MMP1 protein CTD PMID:15309715 lipopolysaccharide multiple interactions ISO MMP1 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein] more ... CTD PMID:18180316 more ... lipopolysaccharide multiple interactions ISO Mmp1b (Mus musculus) 6480464 [Lipopolysaccharides co-treated with Zymosan] results in decreased activity of MMP1 protein and [Lipopolysaccharides co-treated with Zymosan] results in increased activity of MMP1 protein CTD PMID:15259001 lipopolysaccharide multiple interactions EXP 6480464 [sodium arsenite co-treated with Lipopolysaccharides] results in decreased expression of MMP1 mRNA and SERPINH1 protein promotes the reaction [[sodium arsenite co-treated with Lipopolysaccharides] results in decreased expression of MMP1 mRNA] CTD PMID:35963424 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of MMP1 protein CTD PMID:11850527 lipopolysaccharide increases secretion ISO MMP1 (Homo sapiens) 6480464 Lipopolysaccharides results in increased secretion of MMP1 protein CTD PMID:18625914 lipopolysaccharide increases expression ISO MMP1 (Homo sapiens) 6480464 Lipopolysaccharides results in increased expression of MMP1 mRNA and Lipopolysaccharides results in increased expression of MMP1 protein CTD PMID:17303203 more ... loliolide multiple interactions ISO MMP1 (Homo sapiens) 6480464 loliolide inhibits the reaction [Hydrogen Peroxide results in increased expression of MMP1 mRNA] CTD PMID:30231594 lucanthone increases expression ISO MMP1 (Homo sapiens) 6480464 Lucanthone results in increased expression of MMP1 mRNA CTD PMID:21148553 luteolin decreases expression ISO MMP1 (Homo sapiens) 6480464 Luteolin results in decreased expression of MMP1 mRNA and Luteolin results in decreased expression of MMP1 protein CTD PMID:21112745 LY294002 multiple interactions ISO MMP1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased expression of MMP1 protein] more ... CTD PMID:19561517 more ... LY294002 decreases expression ISO Mmp1b (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of MMP1 mRNA CTD PMID:19393235 and PMID:22326785 LY294002 decreases activity ISO Mmp1b (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased activity of MMP1 protein CTD PMID:19393235 and PMID:22326785 malathion increases expression ISO MMP1 (Homo sapiens) 6480464 Malathion results in increased expression of MMP1 mRNA CTD PMID:37047231 medroxyprogesterone acetate decreases expression ISO MMP1 (Homo sapiens) 6480464 Medroxyprogesterone Acetate results in decreased expression of MMP1 mRNA CTD PMID:20843944 mercury dichloride decreases expression EXP 6480464 Mercuric Chloride results in decreased expression of MMP1 mRNA CTD PMID:11817102 Methanandamide increases expression ISO MMP1 (Homo sapiens) 6480464 methanandamide results in increased expression of MMP1 mRNA and methanandamide results in increased expression of MMP1 protein CTD PMID:16330497 methotrexate increases expression ISO MMP1 (Homo sapiens) 6480464 Methotrexate results in increased expression of MMP1 mRNA CTD PMID:21678067 methotrexate affects expression ISO Mmp1b (Mus musculus) 6480464 Methotrexate affects the expression of MMP1B mRNA CTD PMID:18502557 methotrexate multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Hydroxychloroquine co-treated with Methotrexate co-treated with Sulfasalazine] results in decreased expression of MMP1 mRNA CTD PMID:28863153 methylisothiazolinone increases expression ISO MMP1 (Homo sapiens) 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of MMP1 mRNA CTD PMID:31629900 methylisothiazolinone increases secretion ISO MMP1 (Homo sapiens) 6480464 2-methyl-4-isothiazolin-3-one results in increased secretion of MMP1 protein CTD PMID:31629900 mevalonic acid multiple interactions ISO MMP1 (Homo sapiens) 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]] more ... CTD PMID:17303772 and PMID:18625914 mibolerone multiple interactions ISO MMP1 (Homo sapiens) 6480464 [mibolerone binds to and results in increased activity of AR protein] inhibits the reaction [ETS1 protein results in increased expression of MMP1 mRNA] more ... CTD PMID:8798622 mifepristone multiple interactions ISO MMP1 (Homo sapiens) 6480464 Mifepristone inhibits the reaction [Dexamethasone results in decreased secretion of MMP1 protein] CTD PMID:15698539 mono(2-ethyl-5-hydroxyhexyl) phthalate increases expression ISO MMP1 (Homo sapiens) 6480464 mono(2-ethyl-5-hydroxyhexyl) phthalate results in increased expression of MMP1 protein CTD PMID:36113809 mono(2-ethyl-5-oxohexyl) phthalate increases expression ISO MMP1 (Homo sapiens) 6480464 mono(2-ethyl-5-oxohexyl)phthalate results in increased expression of MMP1 protein CTD PMID:36113809 mono(2-ethylhexyl) phthalate increases expression ISO MMP1 (Homo sapiens) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of MMP1 mRNA CTD PMID:36695872 mono(5-carboxy-2-ethylpentyl) phthalate increases expression ISO MMP1 (Homo sapiens) 6480464 2-ethyl-5-carboxypentyl phthalate results in increased expression of MMP1 protein CTD PMID:36113809 Monobutylphthalate increases expression ISO MMP1 (Homo sapiens) 6480464 monobutyl phthalate results in increased expression of MMP1 protein CTD PMID:36113809 moxifloxacin increases secretion ISO MMP1 (Homo sapiens) 6480464 Moxifloxacin results in increased secretion of MMP1 protein CTD PMID:24890593 moxifloxacin decreases secretion ISO MMP1 (Homo sapiens) 6480464 Moxifloxacin results in decreased secretion of MMP1 protein CTD PMID:24890593 N-acetyl-L-cysteine multiple interactions ISO MMP1 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12 more ... CTD PMID:17449795 more ... N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of MMP1 mRNA CTD PMID:16270385 N-nitrosodimethylamine multiple interactions EXP 6480464 Drugs more ... CTD PMID:16270385 nickel atom increases expression ISO MMP1 (Homo sapiens) 6480464 Nickel results in increased expression of MMP1 mRNA CTD PMID:25583101 nickel sulfate increases expression ISO MMP1 (Homo sapiens) 6480464 nickel sulfate results in increased expression of MMP1 mRNA CTD PMID:16780908 nicotine multiple interactions ISO MMP1 (Homo sapiens) 6480464 lipopolysaccharide more ... CTD PMID:17151781 and PMID:18986645 nicotine increases expression ISO MMP1 (Homo sapiens) 6480464 Nicotine results in increased expression of MMP1 mRNA and Nicotine results in increased expression of MMP1 protein CTD PMID:17151781 and PMID:18986645 norfloxacin multiple interactions ISO MMP1 (Homo sapiens) 6480464 Norfloxacin promotes the reaction [IL1B protein results in increased expression of MMP1 mRNA] and Norfloxacin promotes the reaction [IL1B protein results in increased secretion of MMP1 protein] CTD PMID:16148020 NSC 23766 multiple interactions ISO MMP1 (Homo sapiens) 6480464 NSC 23766 inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein] CTD PMID:18625914 NSC 23766 decreases secretion ISO MMP1 (Homo sapiens) 6480464 NSC 23766 results in decreased secretion of MMP1 protein CTD PMID:36009428 okadaic acid increases expression ISO MMP1 (Homo sapiens) 6480464 Okadaic Acid results in increased expression of MMP1 mRNA CTD PMID:28939011 organoselenium compound multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Organoselenium Compounds binds to Copper] which results in increased expression of MMP1 mRNA CTD PMID:25167922 paclitaxel affects response to substance ISO MMP1 (Homo sapiens) 6480464 MMP1 protein affects the susceptibility to Paclitaxel CTD PMID:16217747 paclitaxel multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Cisplatin co-treated with Paclitaxel] results in decreased expression of MMP1 mRNA CTD PMID:20705681 paracetamol increases expression ISO MMP1 (Homo sapiens) 6480464 Acetaminophen results in increased expression of MMP1 mRNA CTD PMID:21420995 paraquat multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Paraquat co-treated with SOD2 protein] results in increased expression of MMP1 mRNA CTD PMID:10464329 paraquat affects expression ISO MMP1 (Homo sapiens) 6480464 Paraquat affects the expression of MMP1 mRNA CTD PMID:34681664 PD 0325901 multiple interactions ISO MMP1 (Homo sapiens) 6480464 [mirdametinib co-treated with (+)-JQ1 compound] results in decreased expression of MMP1 mRNA CTD PMID:25119042 PD 0325901 decreases expression ISO MMP1 (Homo sapiens) 6480464 mirdametinib results in decreased expression of MMP1 mRNA CTD PMID:25119042 pentanal increases expression ISO MMP1 (Homo sapiens) 6480464 pentanal results in increased expression of MMP1 mRNA CTD PMID:26079696 peptidoglycan increases expression ISO MMP1 (Homo sapiens) 6480464 Peptidoglycan results in increased expression of MMP1 mRNA CTD PMID:15860229 perfluorodecanoic acid affects expression ISO MMP1 (Homo sapiens) 6480464 perfluorodecanoic acid affects the expression of MMP1 protein CTD PMID:33677611 perfluorooctanesulfonamide affects expression ISO MMP1 (Homo sapiens) 6480464 perfluorooctanesulfonamide affects the expression of MMP1 protein CTD PMID:33677611 phenobarbital affects expression ISO MMP1 (Homo sapiens) 6480464 Phenobarbital affects the expression of MMP1 mRNA CTD PMID:19159669 phenytoin decreases expression ISO MMP1 (Homo sapiens) 6480464 Phenytoin results in decreased expression of MMP1 mRNA CTD PMID:15948689 phenytoin increases expression ISO MMP1 (Homo sapiens) 6480464 Phenytoin results in increased expression of MMP1 mRNA CTD PMID:10914799 and PMID:14741686 phorbol 13-acetate 12-myristate multiple interactions ISO MMP1 (Homo sapiens) 6480464 BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA] more ... CTD PMID:16176868 more ... phorbol 13-acetate 12-myristate increases expression ISO MMP1 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA and Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein CTD PMID:16176868 more ... phosphocholine multiple interactions ISO MMP1 (Homo sapiens) 6480464 Genistein inhibits the reaction [Phosphorylcholine analog results in increased expression of MMP1 mRNA] and herbimycin inhibits the reaction [Phosphorylcholine analog results in increased expression of MMP1 mRNA] CTD PMID:15878362 phosphocholine increases expression ISO MMP1 (Homo sapiens) 6480464 Phosphorylcholine analog results in increased expression of MMP1 mRNA CTD PMID:15878362 phosphorylcholine chloride multiple interactions ISO MMP1 (Homo sapiens) 6480464 Genistein inhibits the reaction [Phosphorylcholine analog results in increased expression of MMP1 mRNA] and herbimycin inhibits the reaction [Phosphorylcholine analog results in increased expression of MMP1 mRNA] CTD PMID:15878362 phosphorylcholine chloride increases expression ISO MMP1 (Homo sapiens) 6480464 Phosphorylcholine analog results in increased expression of MMP1 mRNA CTD PMID:15878362 platycodin D multiple interactions ISO MMP1 (Homo sapiens) 6480464 platycodin D inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein] CTD PMID:27743553 polymyxin B2 multiple interactions ISO MMP1 (Homo sapiens) 6480464 Polymyxin B inhibits the reaction [lipopolysaccharide more ... CTD PMID:18986645 potassium chromate increases expression ISO MMP1 (Homo sapiens) 6480464 potassium chromate(VI) results in increased expression of MMP1 mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO MMP1 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of MMP1 mRNA CTD PMID:22079256 Praeruptorin A multiple interactions ISO MMP1 (Homo sapiens) 6480464 MAPK1 protein affects the reaction [praeruptorin A results in decreased expression of MMP1 mRNA] CTD PMID:33226171 Praeruptorin A decreases expression ISO MMP1 (Homo sapiens) 6480464 praeruptorin A results in decreased expression of MMP1 mRNA and praeruptorin A results in decreased expression of MMP1 protein CTD PMID:33226171 progesterone multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of MMP1 mRNA more ... CTD PMID:17404688 more ... propanal increases expression ISO MMP1 (Homo sapiens) 6480464 propionaldehyde results in increased expression of MMP1 mRNA CTD PMID:26079696 protein kinase inhibitor multiple interactions ISO Mmp1b (Mus musculus) 6480464 [Protein Kinase Inhibitors results in decreased activity of PTK2 protein] inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA] CTD PMID:30098273 pyrrolidine dithiocarbamate multiple interactions ISO MMP1 (Homo sapiens) 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of MMP1 protein]] and pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]] CTD PMID:32613688 quartz increases expression ISO MMP1 (Homo sapiens) 6480464 Quartz results in increased expression of MMP1 mRNA CTD PMID:27381660 quercetin multiple interactions ISO MMP1 (Homo sapiens) 6480464 Quercetin inhibits the reaction [Cholesterol more ... CTD PMID:11414687 and PMID:22592909 quercetin increases expression ISO MMP1 (Homo sapiens) 6480464 Quercetin results in increased expression of MMP1 mRNA CTD PMID:21632981 quercetin decreases expression ISO MMP1 (Homo sapiens) 6480464 Quercetin results in decreased expression of MMP1 mRNA and Quercetin results in decreased expression of MMP1 protein CTD PMID:11414687 more ... rac-lactic acid affects expression ISO MMP1 (Homo sapiens) 6480464 Lactic Acid affects the expression of MMP1 mRNA CTD PMID:30851411 reactive oxygen species multiple interactions ISO MMP1 (Homo sapiens) 6480464 [[[15-deoxy-delta(12 more ... CTD PMID:19136476 resveratrol multiple interactions ISO MMP1 (Homo sapiens) 6480464 6-chloro-2 more ... CTD PMID:18759268 more ... resveratrol multiple interactions ISO Mmp1b (Mus musculus) 6480464 [Hyaluronic Acid co-treated with Resveratrol] results in decreased expression of MMP1 mRNA CTD PMID:23595953 rofecoxib increases expression ISO MMP1 (Homo sapiens) 6480464 rofecoxib results in increased expression of MMP1 mRNA CTD PMID:16580899 rotenone increases expression ISO MMP1 (Homo sapiens) 6480464 Rotenone results in increased expression of MMP1 mRNA CTD PMID:37394047 ruthenium red multiple interactions ISO MMP1 (Homo sapiens) 6480464 Ruthenium Red inhibits the reaction [Vehicle Emissions results in increased secretion of MMP1 protein] CTD PMID:21245013 ruthenium red affects expression ISO MMP1 (Homo sapiens) 6480464 Ruthenium Red affects the expression of MMP1 mRNA and Ruthenium Red affects the expression of MMP1 protein CTD PMID:17508023 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO MMP1 (Homo sapiens) 6480464 [S-(1 more ... CTD PMID:35811015 S-(1,2-dichlorovinyl)-L-cysteine decreases expression ISO MMP1 (Homo sapiens) 6480464 S-(1 and 2-dichlorovinyl)cysteine results in decreased expression of MMP1 mRNA CTD PMID:35811015 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Buthionine Sulfoximine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA and Deferoxamine inhibits the reaction [[Buthionine Sulfoximine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA] CTD PMID:10464329 SB 203580 multiple interactions ISO MMP1 (Homo sapiens) 6480464 SB 203580 inhibits the reaction [2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of and results in increased activity of MMP1 protein] more ... CTD PMID:20004183 more ... SB 431542 multiple interactions ISO MMP1 (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with EGF protein co-treated with FGF2 protein] results in increased expression of MMP1 mRNA CTD PMID:34480604 selumetinib decreases activity ISO MMP1 (Homo sapiens) 6480464 AZD 6244 results in decreased activity of MMP1 protein CTD PMID:31790661 senecionine increases expression ISO MMP1 (Homo sapiens) 6480464 senecionine results in increased expression of MMP1 mRNA CTD PMID:26100227 Senkirkine increases expression ISO MMP1 (Homo sapiens) 6480464 senkirkine results in increased expression of MMP1 mRNA CTD PMID:26100227 serpentine asbestos increases expression ISO MMP1 (Homo sapiens) 6480464 Asbestos and Serpentine results in increased expression of MMP1 mRNA CTD PMID:24160326 silicon dioxide increases expression ISO MMP1 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of MMP1 mRNA and Silicon Dioxide results in increased expression of MMP1 mRNA CTD PMID:22300531 more ... silicon dioxide multiple interactions ISO MMP1 (Homo sapiens) 6480464 SULF1 mRNA promotes the reaction [Silicon Dioxide results in increased expression of MMP1 mRNA] CTD PMID:29673857 simvastatin multiple interactions ISO MMP1 (Homo sapiens) 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP1]] more ... CTD PMID:17303772 more ... simvastatin increases expression ISO MMP1 (Homo sapiens) 6480464 Simvastatin results in increased expression of MMP1 mRNA CTD PMID:17428261 simvastatin decreases secretion ISO MMP1 (Homo sapiens) 6480464 Simvastatin results in decreased secretion of MMP1 mRNA and Simvastatin results in decreased secretion of MMP1 protein CTD PMID:17303772 simvastatin decreases expression ISO MMP1 (Homo sapiens) 6480464 Simvastatin results in decreased expression of MMP1 protein CTD PMID:17303772 sirolimus increases secretion ISO MMP1 (Homo sapiens) 6480464 Sirolimus results in increased secretion of MMP1 protein CTD PMID:21742783 sirolimus increases expression ISO MMP1 (Homo sapiens) 6480464 Sirolimus results in increased expression of MMP1 mRNA CTD PMID:21742783 sodium arsenite decreases expression ISO MMP1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of MMP1 mRNA CTD PMID:12377979 and PMID:30191986 sodium arsenite multiple interactions ISO MMP1 (Homo sapiens) 6480464 ATF2 protein promotes the reaction [sodium arsenite results in increased expression of MMP1 mRNA] CTD PMID:30090515 sodium arsenite multiple interactions EXP 6480464 [sodium arsenite co-treated with Lipopolysaccharides] results in decreased expression of MMP1 mRNA and SERPINH1 protein promotes the reaction [[sodium arsenite co-treated with Lipopolysaccharides] results in decreased expression of MMP1 mRNA] CTD PMID:35963424 sodium arsenite affects expression ISO MMP1 (Homo sapiens) 6480464 sodium arsenite affects the expression of MMP1 mRNA CTD PMID:34032870 sodium arsenite increases expression ISO MMP1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of MMP1 mRNA and sodium arsenite results in increased expression of MMP1 protein CTD PMID:22714537 more ... sodium azide multiple interactions ISO MMP1 (Homo sapiens) 6480464 Sodium Azide inhibits the reaction [Aminolevulinic Acid affects the expression of MMP1 protein] and Sodium Azide inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MMP1 mRNA] CTD PMID:10836612 and PMID:12542540 sotorasib multiple interactions ISO MMP1 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MMP1 mRNA CTD PMID:36139627 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of MMP1 protein CTD PMID:35993117 sulfasalazine multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Hydroxychloroquine co-treated with Methotrexate co-treated with Sulfasalazine] results in decreased expression of MMP1 mRNA CTD PMID:28863153 sulindac sulfide decreases expression ISO MMP1 (Homo sapiens) 6480464 sulindac sulfide results in decreased expression of MMP1 mRNA CTD PMID:15767558 sulindac sulfide increases expression ISO MMP1 (Homo sapiens) 6480464 sulindac sulfide results in increased expression of MMP1 mRNA CTD PMID:16184548 sunitinib decreases expression ISO MMP1 (Homo sapiens) 6480464 Sunitinib results in decreased expression of MMP1 mRNA CTD PMID:31533062 T-2 toxin increases expression ISO MMP1 (Homo sapiens) 6480464 T-2 Toxin results in increased expression of MMP1 protein CTD PMID:21144892 tamoxifen multiple interactions ISO MMP1 (Homo sapiens) 6480464 Tamoxifen promotes the reaction [ESR1 protein binds to MMP1 promoter] and Tamoxifen promotes the reaction [FOS protein binds to MMP1 promoter] CTD PMID:17157789 tamoxifen decreases activity ISO Mmp1b (Mus musculus) 6480464 Tamoxifen results in decreased activity of MMP1 protein CTD PMID:19393235 tamoxifen decreases expression ISO Mmp1b (Mus musculus) 6480464 Tamoxifen results in decreased expression of MMP1 mRNA CTD PMID:19393235 Tanshinone I multiple interactions ISO Mmp1b (Mus musculus) 6480464 tanshinone inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA] CTD PMID:30098273 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of MMP1 protein CTD PMID:17094476 tetrachloromethane increases expression ISO Mmp1b (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of MMP1 mRNA and Carbon Tetrachloride results in increased expression of MMP1 protein CTD PMID:16508911 tetrachloromethane multiple interactions ISO Mmp1b (Mus musculus) 6480464 POMC protein promotes the reaction [Carbon Tetrachloride results in increased expression of MMP1 protein] CTD PMID:16508911 thioacetamide multiple interactions ISO Mmp1b (Mus musculus) 6480464 POMC protein alternative form promotes the reaction [Thioacetamide results in increased expression of MMP1 mRNA] CTD PMID:16511523 thioacetamide increases expression ISO Mmp1b (Mus musculus) 6480464 Thioacetamide results in increased expression of MMP1 mRNA and Thioacetamide results in increased expression of MMP1 protein CTD PMID:16511523 and PMID:30625377 thymidine multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Thymidine co-treated with TYMP protein] results in increased expression of MMP1 protein and Thymine inhibits the reaction [[Thymidine co-treated with TYMP protein] results in increased expression of MMP1 protein] CTD PMID:11103787 thymine multiple interactions ISO MMP1 (Homo sapiens) 6480464 Thymine inhibits the reaction [[Thymidine co-treated with TYMP protein] results in increased expression of MMP1 protein] CTD PMID:11103787 Tiron multiple interactions ISO MMP1 (Homo sapiens) 6480464 1 more ... CTD PMID:16987005 titanium dioxide multiple interactions ISO MMP1 (Homo sapiens) 6480464 [Vitallium analog binds to titanium dioxide] which results in increased expression of MMP1 mRNA CTD PMID:23825117 tofacitinib decreases expression ISO MMP1 (Homo sapiens) 6480464 tofacitinib results in decreased expression of MMP1 mRNA CTD PMID:25398374 topotecan affects response to substance ISO MMP1 (Homo sapiens) 6480464 MMP1 protein affects the susceptibility to Topotecan CTD PMID:16217747 trametinib multiple interactions ISO MMP1 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of MMP1 mRNA CTD PMID:36139627 trichostatin A multiple interactions ISO MMP1 (Homo sapiens) 6480464 CAT protein affects the reaction [trichostatin A promotes the reaction [SOD2 protein results in increased expression of MMP1 mRNA]] and trichostatin A promotes the reaction [SOD2 protein results in increased expression of MMP1 mRNA] CTD PMID:24973648 triclosan affects expression ISO MMP1 (Homo sapiens) 6480464 Triclosan affects the expression of MMP1 mRNA CTD PMID:34681664 tubocurarine multiple interactions ISO MMP1 (Homo sapiens) 6480464 Tubocurarine inhibits the reaction [lipopolysaccharide more ... CTD PMID:17151781 and PMID:18986645 Tungsten carbide multiple interactions ISO MMP1 (Homo sapiens) 6480464 [tungsten carbide binds to Cobalt] which results in decreased expression of MMP1 mRNA CTD PMID:20105288 Tungsten carbide decreases expression ISO MMP1 (Homo sapiens) 6480464 tungsten carbide results in decreased expression of MMP1 mRNA CTD PMID:20105288 tunicamycin increases expression ISO MMP1 (Homo sapiens) 6480464 Tunicamycin results in increased expression of MMP1 mRNA CTD PMID:33545341 tyrphostin AG 1478 multiple interactions ISO MMP1 (Homo sapiens) 6480464 RTKI cpd inhibits the reaction [EGF protein results in increased secretion of MMP1 protein] more ... CTD PMID:17656145 U-73122 multiple interactions ISO MMP1 (Homo sapiens) 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:21245013 Ursonic acid multiple interactions ISO MMP1 (Homo sapiens) 6480464 Hydrogen Peroxide inhibits the reaction [ursonic acid results in decreased expression of MMP1 mRNA] and ursonic acid results in decreased activity of and results in decreased secretion of MMP1 protein CTD PMID:31790661 Ursonic acid decreases expression ISO MMP1 (Homo sapiens) 6480464 ursonic acid results in decreased expression of MMP1 mRNA CTD PMID:31790661 vanadium atom decreases expression ISO MMP1 (Homo sapiens) 6480464 Vanadium results in decreased expression of MMP1 mRNA CTD PMID:19000753 vanadium(0) decreases expression ISO MMP1 (Homo sapiens) 6480464 Vanadium results in decreased expression of MMP1 mRNA CTD PMID:19000753 vanadyl sulfate increases expression ISO MMP1 (Homo sapiens) 6480464 vanadyl sulfate results in increased expression of MMP1 mRNA and vanadyl sulfate results in increased expression of MMP1 protein CTD PMID:18684396 varespladib methyl multiple interactions ISO MMP1 (Homo sapiens) 6480464 varespladib methyl inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA] and varespladib methyl inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein] CTD PMID:19765281 vemurafenib multiple interactions ISO MMP1 (Homo sapiens) 6480464 [(+)-JQ1 compound co-treated with vemurafenib] results in decreased expression of MMP1 mRNA CTD PMID:27169980 vincaleukoblastine affects response to substance ISO MMP1 (Homo sapiens) 6480464 MMP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 XAV939 multiple interactions ISO MMP1 (Homo sapiens) 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MMP1 mRNA and [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MMP1 mRNA CTD PMID:34480604