Cks2 (CDC28 protein kinase regulatory subunit 2)

Gene: Cks2 (CDC28 protein kinase regulatory subunit 2) Rattus norvegicus

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Symbol:

Cks2

Name:

CDC28 protein kinase regulatory subunit 2

Description:

Predicted to have several functions, including cyclin-dependent protein serine/threonine kinase activator activity; histone binding activity; and ubiquitin binding activity. Predicted to be involved in several processes, including cell population proliferation; meiosis I; and mitotic cell cycle phase transition. Predicted to localize to the SCF ubiquitin ligase complex and cyclin-dependent protein kinase holoenzyme complex. Orthologous to human CKS2 (CDC28 protein kinase regulatory subunit 2); PARTICIPATES IN small cell lung carcinoma pathway; INTERACTS WITH (+)-schisandrin B; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

cyclin-dependent kinases regulatory subunit 2; LOC498709; RGD1562047; similar to Cyclin-dependent kinases regulatory subunit 2 (CKS-2)

Orthologs:

Homo sapiens (human) : CKS2 (CDC28 protein kinase regulatory subunit 2) HGNC Alliance
Mus musculus (house mouse) : Cks2 (CDC28 protein kinase regulatory subunit 2) MGI Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cks2 (CDC28 protein kinase regulatory subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CKS2 (CDC28 protein kinase regulatory subunit 2)
Canis lupus familiaris (dog) : CKS2 (CDC28 protein kinase regulatory subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cks2 (CDC28 protein kinase regulatory subunit 2)
Sus scrofa (pig) : CKS2 (CDC28 protein kinase regulatory subunit 2)

more info ...

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CKS2 (CDC28 protein kinase regulatory subunit 2)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Cks2 (CDC28 protein kinase regulatory subunit 2)	HGNC	Treefam, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Cks2 (CDC28 protein kinase regulatory subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CKS2 (CDC28 protein kinase regulatory subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CKS2 (CDC28 protein kinase regulatory subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cks2 (CDC28 protein kinase regulatory subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CKS2 (CDC28 protein kinase regulatory subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CKS2 (CDC28 protein kinase regulatory subunit 2)	Alliance	DIOPT (HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Mus musculus (house mouse):	Cks2 (CDC28 protein kinase regulatory subunit 2)	Alliance	DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):	cks2 (CDC28 protein kinase regulatory subunit 2)	Alliance	DIOPT (OrthoFinder, PANTHER, PhylomeDB, TreeFam)
Saccharomyces cerevisiae (baker's yeast):	CKS1	Alliance	DIOPT (Ensembl Compara, Hieranoid, InParanoid, OrthoFinder, OrthoInspector, PANTHER, TreeFam)
Drosophila melanogaster (fruit fly):	Cks30A	Alliance	DIOPT (Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PhylomeDB, TreeFam)
Drosophila melanogaster (fruit fly):	Cks85A	Alliance	DIOPT (Ensembl Compara, Hieranoid, OMA, OrthoFinder, TreeFam)
Caenorhabditis elegans (roundworm):	cks-1	Alliance	DIOPT (Hieranoid, OMA, OrthoFinder, OrthoInspector, TreeFam)
Caenorhabditis elegans (roundworm):	Y71G12B.27	Alliance	DIOPT (InParanoid, OrthoFinder, OrthoInspector, PANTHER, TreeFam)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	17	13,587,664 - 13,593,423 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	17	15,662,365 - 15,667,466 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	19,423,502 - 19,429,451 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	17	13,326,389 - 13,331,548 (-)	NCBI		Celera
Cytogenetic Map	17	p14	NCBI

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View Region in Genome Browser (JBrowse)

Model

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Disease Annotations

Gene-Chemical Interaction Annotations

Gene Ontology Annotations

Molecular Pathway Annotations

References - curated

References - uncurated

Genomics

Comparative Map Data

QTLs in Region (Rnor_6.0)

miRNA Target Status

Sequence

Nucleotide Sequences

Protein Sequences

Transcriptome

Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links

Nomenclature History

More on Cks2
	Alliance Gene
	NCBI Gene
	Ensembl Gene
	JBrowse: rn5 rn6
	NCBI Genome Data Viewer

RGD Object Information
RGD ID:	1562047
Created:	2006-02-09
Species:	Rattus norvegicus
Last Modified:	2019-08-20
Status:	ACTIVE

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

Functional Annotation unavailable	Annotation Distribution unavailable	Genomic Variants unavailble Genomic Variants unavailable
Functional Annotation	Annotation Distribution	Genomic Variants

Protein-Protein Interactions unavailable	Genome Viewer unavailable	Damaging Variants unavailble Damaging Variants unavailable
Protein-Protein Interactions	Genome Viewer	Damaging Variants

Annotation Comparison unavailable	OLGA unavailable
Annotation Comparison	OLGA	Excel (Download)

Gene Enrichment unavailable	Ortholog Finder unavailable
Gene Enrichment	Ortholog Finder

Imported Annotations - CTD

Imported Annotations - KEGG (archival)