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Gene: Xrcc1 (X-ray repair cross complementing 1) Rattus norvegicus
Symbol: Xrcc1
Name: X-ray repair cross complementing 1
Description: Predicted to contribute to 3' overhang single-stranded DNA endodeoxyribonuclease activity. Involved in several processes, including base-excision repair; response to drug; and response to hypoxia. Localizes to nucleus. Used to study in situ carcinoma. Biomarker of asphyxia neonatorum; transient cerebral ischemia; and visual epilepsy. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive spinocerebellar ataxia 26; hematologic cancer (multiple); hepatobiliary system cancer (multiple); reproductive organ cancer (multiple); and urinary system cancer (multiple). Orthologous to human XRCC1 (X-ray repair cross complementing 1); PARTICIPATES IN base excision repair pathway; nucleotide excision repair pathway; INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: DNA repair protein XRCC1; X-ray repair complementing defective repair in Chinese hamster cells 1; x-ray repair cross-complementing group 1 protein; X-ray repair cross-complementing protein 1
Homo sapiens (human) : XRCC1 (X-ray repair cross complementing 1)  HGNC  Alliance
Mus musculus (house mouse) : Xrcc1 (X-ray repair complementing defective repair in Chinese hamster cells 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xrcc1 (X-ray repair cross complementing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : XRCC1 (X-ray repair cross complementing 1)
Canis lupus familiaris (dog) : XRCC1 (X-ray repair cross complementing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xrcc1 (X-ray repair cross complementing 1)
Sus scrofa (pig) : XRCC1 (X-ray repair cross complementing 1)
Chlorocebus sabaeus (African green monkey) : XRCC1 (X-ray repair cross complementing 1)
Heterocephalus glaber (naked mole-rat) : Xrcc1 (X-ray repair cross complementing 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0181,412,635 - 81,441,680 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl181,413,353 - 81,441,678 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0182,673,571 - 82,701,082 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4179,834,167 - 79,860,300 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1179,912,277 - 79,938,411 (+)NCBI
Celera174,594,313 - 74,621,523 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Xrcc1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619823
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.