GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Xrcc1 | affects response to substance | ISO | XRCC1 (Homo sapiens) | 6480464 | CTD | XRCC1 protein affects the susceptibility to Etoposide | PMID:26046675 | Xrcc1 | increases expression | ISO | XRCC1 (Homo sapiens) | 6480464 | CTD | Etoposide results in increased expression of XRCC1 mRNA; Etoposide results in increased expression of XRCC1 protein | PMID:26046675 | Xrcc1 | multiple interactions | ISO | XRCC1 (Homo sapiens) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Etoposide results in increased expression of XRCC1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Etoposide results in increased expression of XRCC1 protein]; resveratrol inhibits the reaction [Etoposide results in increased expression of XRCC1 mRNA]; resveratrol inhibits the reaction [Etoposide results in increased expression of XRCC1 protein]; U 0126 inhibits the reaction [Etoposide results in increased expression of XRCC1 mRNA]; U 0126 inhibits the reaction [Etoposide results in increased expression of XRCC1 protein] | PMID:26046675 | | ||||||||||||||||||||||
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