Gene: Mllt11 (MLLT11, transcription factor 7 cofactor) Rattus norvegicus
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Symbol: Mllt11
Name: MLLT11, transcription factor 7 cofactor
Description: INVOLVED IN extrinsic apoptotic signaling pathway (ortholog); intrinsic apoptotic signaling pathway (ortholog); positive regulation of apoptotic process (ortholog); ASSOCIATED WITH acute myelomonocytic leukemia; FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil
AGR Description: Predicted to be involved in several processes, including apoptotic signaling pathway, positive regulation of mitochondrial depolarization, and positive regulation of release of cytochrome c from mitochondria; predicted to localize to the cytosol and nucleoplasm; orthologous to human MLLT11 (MLLT11 transcription factor 7 cofactor).
Merged Description: Predicted to be involved in several processes, including apoptotic signaling pathway, positive regulation of mitochondrial depolarization, and positive regulation of release of cytochrome c from mitochondria; predicted to localize to the cytosol and nucleoplasm; orthologous to human MLLT11 (MLLT11 transcription factor 7 cofactor); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AF1Q protein; LOC295264; myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11; protein AF1q; RGD1305525; similar to AF1q; translocated to, 11
Orthologs:
Homo sapiens (human) : MLLT11 (MLLT11 transcription factor 7 cofactor)  HGNC  Alliance
Mus musculus (house mouse) : Mllt11 (myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mllt11 (MLLT11 transcription factor 7 cofactor)
Pan paniscus (bonobo/pygmy chimpanzee) : MLLT11 (MLLT11 transcription factor 7 cofactor)
Canis lupus familiaris (dog) : MLLT11 (MLLT11, transcription factor 7 cofactor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mllt11 (MLLT11 transcription factor 7 cofactor)
Sus scrofa (pig) : MLLT11 (MLLT11 transcription factor 7 cofactor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02196,392,936 - 196,402,106 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02215,889,654 - 215,898,937 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42190,127,887 - 190,137,658 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12190,090,642 - 190,100,412 (-)NCBI
Celera2175,329,532 - 175,338,610 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mllt11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305525
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.